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Gene: Flywch1 (FLYWCH-type zinc finger 1) Rattus norvegicus

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Symbol:

Flywch1

Name:

FLYWCH-type zinc finger 1

RGD ID:

1309385

Description:

Predicted to enable transcription coactivator binding activity and transcription corepressor activity. Predicted to be involved in DNA damage response and negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body and pericentric heterochromatin. Predicted to be part of transcription regulator complex. Orthologous to human FLYWCH1 (FLYWCH-type zinc finger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

FLYWCH-type zinc finger-containing protein 1; LOC360488; RGD1309385; similar to RIKEN cDNA E030034P13

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FLYWCH1 (FLYWCH-type zinc finger 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Flywch1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Flywch1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FLYWCH1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FLYWCH1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Flywch1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FLYWCH1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FLYWCH1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Flywch1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Flywch1 (FLYWCH-type zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC22A4 (solute carrier family 22 member 4)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	FLYWCH1 (FLYWCH-type zinc finger 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Flywch1 (FLYWCH-type zinc finger 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	pre-mod(mdg4)-J	Alliance	DIOPT (OrthoFinder\|PhylomeDB)
Drosophila melanogaster (fruit fly):	pre-mod(mdg4)-J	Alliance	DIOPT (OrthoFinder\|PhylomeDB)
Drosophila melanogaster (fruit fly):	pre-mod(mdg4)-B	Alliance	DIOPT (OrthoFinder\|PhylomeDB)
Drosophila melanogaster (fruit fly):	pre-mod(mdg4)-O	Alliance	DIOPT (OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	13,279,232 - 13,298,955 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	13,279,232 - 13,298,925 (-)	Ensembl				GRCr8
mRatBN7.2	10	12,774,644 - 12,794,373 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	12,774,653 - 12,794,267 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	17,518,924 - 17,539,034 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	17,007,713 - 17,027,823 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	12,507,291 - 12,527,000 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	13,087,925 - 13,107,833 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	13,087,914 - 13,107,771 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	12,907,389 - 12,927,264 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	13,013,234 - 13,036,965 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	12,469,943 - 12,489,573 (-)	NCBI		Celera
RGSC_v3.1	10	13,009,876 - 13,021,779 (-)	NCBI
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Silver-Russell syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

cocaine (EXP)

DDE (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

N-nitrosodiethylamine (ISO)

nefazodone (EXP)

Nutlin-3 (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorononanoic acid (ISO)

piperonyl butoxide (ISO)

propanal (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

Cellular Component

chromosome, centromeric region (IEA)

nuclear body (IEA,ISO)

nucleus (IEA)

pericentric heterochromatin (IEA,ISO)

transcription regulator complex (IEA,ISO)

Molecular Function

DNA binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

transcription coactivator binding (IEA,ISO)

transcription corepressor activity (IEA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Flywch1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	13,279,232 - 13,298,955 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	13,279,232 - 13,298,925 (-)	Ensembl				GRCr8
mRatBN7.2	10	12,774,644 - 12,794,373 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	12,774,653 - 12,794,267 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	17,518,924 - 17,539,034 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	17,007,713 - 17,027,823 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	12,507,291 - 12,527,000 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	13,087,925 - 13,107,833 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	13,087,914 - 13,107,771 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	12,907,389 - 12,927,264 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	13,013,234 - 13,036,965 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	12,469,943 - 12,489,573 (-)	NCBI		Celera
RGSC_v3.1	10	13,009,876 - 13,021,779 (-)	NCBI
Cytogenetic Map	10	q12	NCBI

FLYWCH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	2,911,931 - 2,951,208 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	2,911,599 - 2,951,208 (+)	Ensembl			hg38	GRCh38
GRCh37	16	2,961,932 - 3,001,209 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	2,901,981 - 2,941,210 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	3,167,373 - 3,206,655 (+)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	2,933,879 - 2,973,694 (+)	NCBI		HuRef
CHM1_1	16	2,961,929 - 3,001,182 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	2,938,537 - 2,977,878 (+)	NCBI		T2T-CHM13v2.0

Flywch1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	23,971,767 - 23,993,504 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	23,971,767 - 23,990,576 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	23,752,795 - 23,774,530 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	23,752,793 - 23,771,602 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	23,892,390 - 23,908,558 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	23,483,045 - 23,491,398 (-)	NCBI		MGSCv36	mm8
Celera	17	24,249,349 - 24,265,342 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.04	NCBI

Flywch1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	14,386,276 - 14,418,328 (-)	Ensembl
ChiLan1.0	NW_004955442	14,392,901 - 14,419,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

FLYWCH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	3,458,497 - 3,494,400 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	7,236,907 - 7,272,783 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	1,827,105 - 1,892,885 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	3,027,645 - 3,064,557 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	3,027,656 - 3,064,557 (+)	Ensembl			panPan2	panpan1.1

FLYWCH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	38,223,341 - 38,246,991 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	38,224,825 - 38,244,866 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	39,463,838 - 39,487,336 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	38,533,925 - 38,571,052 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	38,533,934 - 38,557,430 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	38,219,679 - 38,243,168 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	38,192,197 - 38,229,284 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	38,667,982 - 38,691,473 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Flywch1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	105,472,907 - 105,496,946 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	1,215,774 - 1,236,606 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	1,212,517 - 1,236,576 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FLYWCH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	39,225,365 - 39,242,675 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	39,223,885 - 39,244,743 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	40,660,183 - 40,680,188 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FLYWCH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	2,654,583 - 2,689,184 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	2,670,081 - 2,690,582 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666068	28,145,121 - 28,220,247 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Flywch1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624824	680,554 - 695,025 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624824	659,892 - 695,997 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Flywch1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	1,054,092 - 1,076,830 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Flywch1
135 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	129
Count of miRNA genes:	75
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000005879, ENSRNOT00000067269
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
631828	Alc5	Alcohol consumption QTL 5	2.4		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	1	17749933	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat

Markers in Region

RH136914

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	12,774,747 - 12,774,928 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	13,088,029 - 13,088,209	NCBI	Rnor6.0
Rnor_5.0	10	12,907,491 - 12,907,671	UniSTS	Rnor5.0
RGSC_v3.4	10	13,009,981 - 13,010,161	UniSTS	RGSC3.4
Celera	10	12,470,047 - 12,470,227	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001056224	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006220586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006220587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC129118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005879 ⟹ ENSRNOP00000005879

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	13,279,232 - 13,298,925 (-)	Ensembl
mRatBN7.2 Ensembl	10	12,774,653 - 12,794,267 (-)	Ensembl
Rnor_6.0 Ensembl	10	13,087,914 - 13,107,771 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134358 ⟹ ENSRNOP00000108628

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	13,279,232 - 13,298,925 (-)	Ensembl

RefSeq Acc Id:

NM_001398792 ⟹ NP_001385721

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,232 - 13,298,925 (-)	NCBI
mRatBN7.2	10	12,774,644 - 12,794,338 (-)	NCBI

RefSeq Acc Id:

XM_006245882 ⟹ XP_006245944

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI
mRatBN7.2	10	12,774,644 - 12,794,373 (-)	NCBI
Rnor_6.0	10	13,087,925 - 13,107,833 (-)	NCBI
Rnor_5.0	10	12,907,389 - 12,927,264 (-)	NCBI

Sequence:

show sequence

TAGGCTTTCCAAGCCAGTGTCTCGCGGGGGCGCGCGCGCGCGCGCGGGCACGGGCTCGCTCCCC
AGGGGGCAGTTGGCGGCGGGAGCGGGCGGCGGGGTCGTGGTTCTTAGAGCAGCACCGGCTGCTA
GGCCGGCGCCTCCATTAGCGGACATTTACACGAAGGACCGGGTGGCTCAGCCGCCGGAGAGGCA
GGGCCCGCTGCCGTCGATAGGGCTTTTCTATGTAGCCCTGATCTGTGGGCCTTGGGTGGGCCTC
ACGATCACAGAGATCTTCCACCCCCTGCCTCCTGAGTGCCAGGATTAAAGGACCGAGGCTCTGA
GTCTCACATTCTGGCCTAGGAGGAGGAAGAGGAGAGACCCATTTGCCAGAGGGCTGAAGGTGGC
CTTGAGGGCCATGCTCTCGGTCCCAGGATGCCCCTGCCTGAGCCCAGTGAGCAGGAGGGTGAGA
GCCTGAGAGCTGGCCAGGAGCCATCCCGTGGAGCTCGGAAACCTCAAGAGTCCTCTAGTCTGGT
CCCGGCCAGGGACAAGGAGAAACCCAAGCCGACAGATGTCATGTCCCAGGAGACGTCCAGCACC
ACCACCCTACCTAACAACACCCTCCAGGCCTTGCCGGCCAAGAAGCAGGGACGGATAATTCACC
GGAAACGTAGTAGGGTAGATGCAGTTGCCCCCCAGCCCCTGGAGTTCCTGAAGACCCCATCTGG
GAGCCGCCTTCTGGTGCACAAGTCGTTCCTTTACAAGCAGGAGAAGGCCGTGGGGGACAAGGTG
TACTGGAAATGCCGCCAGCACTCAGAGCTGGGCTGCCGGGGCCGGGCCATCACTCGTGGCTTTC
GAGTCACAGAGATGCGGGACCATTGTCACCCACCTGAAAAGGAAGGCCTGGGAAAGAAAAGGCG
CCAGAAGGAAAAGCTGCCCAGCTCGGGCACTGAAGGCCAAGGAGATGGGGTGAGCTTGTGGCTG
TACCCTGTGGAGCCGGAACCCACCCCTCAGCCAAGCATCGAAACCCCAGAGGAGGAGCAGGGGT
ACCGCTCCCTGGCACTGCAGAGCCTGCCTCCCAAGAAACGCCCCACCCCAGGAGTGGTACGGTA
TCGGCCTCTTGAGTTCCTGAAGACCTGCTACGGGGGGACCTTCCTGGTGCACCAGTCCTTCCTC
TACAAGCGGGAGAAGACAGTAGGAAGCAAGGTGTACTGGACCTGCCGGGAACATGCGGTCCATG
GCTGCCGCAGCCGTGCCATCACCCAGGGCCAGCGCGTGACGGTGATGCGCAGCCACTGCCACTC
ACCTGACATGGAAGGCTTGCAGGCCCGGCGGCAGCAGGAGAAGACCATAAAGAAGATACAGGCA
AGGCGGATTGGGGCTGGGGACCTGGAGGATTGTGATGACATTGAAGACACACTGCTGCAAGGGG
TGGACAGCCTGTTCTACCGCAGAGGGCCAGGCACACTGACTCTCAGTAGATCCAGGTCCAGGAA
ACGAGCAAAGAAGCAGCAGGAACCCTTGCAGGAATCCCCCGAGGAGGAGGACCAGGATGTGGAC
CCCAAAGGCCCAGAGTTCCTGAAGACCCCTCTGGGGGGCAACTTCCTGGTGTACGAGTCCTTCC
TCTACAGACGGGAAAAAGTGGCCGGAGAGAAGGTGTACTGGACTTGCCGGGACCAGGCACGCAT
GGGCTGCCGCAGCCGGGCCATCACCCAGGGCAGGCAGGTGACTGTGATGCGAGGCCACTGTCAC
CCACCTGACCTGTTAGGATTGGAGACTCTGAGGCAGCGGCAGAAACGCCCAGGCCCTGCTCAGT
GGGATGGCCCAGAAGGGCCTGAGTTCCTGAAGACCCCTCTGGGGGGCAGCTTCCTGGTGTACGA
GTCCTTCCTCTACAGGCGGGAGAAAGCGACCGGCGATAAGGTGTACTGGACTTGCCGGGACCAG
GCACGCATGGGTTGCCGCAGCCGCGCCATCACCCAGGGCCAGCGGGTGATGGTCATGCGCAGGC
ACTGCCACCCACCAGACATGGGTGGCCTGGAAGCCCTGCGGCAGAGGGAGAACTTCCCTAACCT
GACCCACTGGGAAGGCCCAGAGCCCGTGCAGCCGCTGGAGTTCCTGCAGACATCCCTTGGAGGC
CGCTTCCTGGTGTACGAGTCCTTCCTGTACAGGAAGGAGAAGGCCGCCGGCGAGAAGGTGTACT
GGATGTGCCGGGACCAGGCTCGGCTGGGCTGCCGCAGCCGCGCCATTACCCAGGGCCGTCGGGT
CATGGTGATGCGAAGCCACTGCCATTCCCCTGACCTGGCTGGCCTGGAGGCCCTGAGGCAGCGG
GAGAGGGAGAAGGCCCGGGAGAGGGAGAAGGCCCGGGAGAGGGAGAAGGCCCCCAGTGCAGCCA
AGAAGAAAAAGAAGAAGAAGAAGAAGAAAGGAAAATCAAAGAGCTAAAACCGATCAGCCAGTCC
TGCTGCAGTATCTTCTCTGGAACAACAGAGGAGCAGCGGGCACCCCAGATGCTTCCCATCCACA
CAGGCGTTCCCATCCATTCAGATGCGCTTGGTGACAACTCTTTCCACTCTTCCAAACACCCAGG
ACCGTCACATTTCCTCAGAGGTCTCCCCGGAGGAGCGCTTGGACTTTGGGTGGTAACCAAGCCG
GATGGGTGGCCTGCAGGCCTGCCCCATGCTGCTCTCACCGTGACCTGAGCTGTGGAGAAGTGTG
TGTGGACTGATAGACCTCTGCCCACTCTGCTGTCCAGGCCTCAGCACCATCTGCTTTCAGAGCA
TGCTGTCTGAGCTTTCCAGTGGGGTGTGACCCTGTGCGAGTGAGCATGAACTTCAGCAAAATGG
AAGTCATCCCAAGTCAGGATATGTACGGGGACTTCCTGCCACTCTCTGAAGACAGTGCAAGTCA
TAGCAGGGTTTTGTTTTGTTATCTTTTAGGGACAGGTGTGAGGCCTTCCTGGTCTTTTGTCACT
TGCTGCTTACTAAGGCACATCCAGCCCTGACCGTGGCAGAGCAGGCCAGGCTGAAGGCTTCGCT
GTACCTTCCTGGCCGACTTTGCATCCTGTGTTCTTTGCTACCTTAAACCTATGTCCACAGTTCT
TGGGCGCCAGCCCAGAGGTCAGGAGGAGGTGACACCAGGTAGGCATGCTCTGGTGGCAGCAGCA
CCACCGAGAGTTGCCCACCTAGTGTCACATGATACACAAGGTCAGTAGGTGGCATCAAGCCCAC
CTCCTGTAGAAGAGGCTAGCAGGACTAAGGAGCCATGTTAGCAGTGGCATTCTAGTGTCCCTGG
GAATGCAGAATCTCCTGTGTGCTGCCCCTGGCCAGAGCTGTCCTCACCCTGTCTCAGAGCTGCA
TGCTCCTCTCCCTTAGCAAGCAAGCCATGGAGCAGCCACCCCTGTGGGATAGTAATGGCCTGGT
GCCTACCACTGGCTTCTGCTCATCTGCTTCCCTCAATAAACCCTATGTAGTCTCACGGTACAGA

hide sequence

RefSeq Acc Id:

XM_039087076 ⟹ XP_038943004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,955 (-)	NCBI
mRatBN7.2	10	12,774,644 - 12,794,373 (-)	NCBI

RefSeq Acc Id:

XM_063269299 ⟹ XP_063125369

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI

RefSeq Acc Id:

XM_063269300 ⟹ XP_063125370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,297,286 (-)	NCBI

RefSeq Acc Id:

XM_063269301 ⟹ XP_063125371

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI

RefSeq Acc Id:

XM_063269302 ⟹ XP_063125372

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI

RefSeq Acc Id:

XM_063269303 ⟹ XP_063125373

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI

RefSeq Acc Id:

XM_063269304 ⟹ XP_063125374

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,297,286 (-)	NCBI

RefSeq Acc Id:

XM_063269305 ⟹ XP_063125375

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	13,279,236 - 13,298,954 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001385721	(Get FASTA)	NCBI Sequence Viewer
	XP_006245944	(Get FASTA)	NCBI Sequence Viewer
	XP_038943004	(Get FASTA)	NCBI Sequence Viewer
	XP_063125369	(Get FASTA)	NCBI Sequence Viewer
	XP_063125370	(Get FASTA)	NCBI Sequence Viewer
	XP_063125371	(Get FASTA)	NCBI Sequence Viewer
	XP_063125372	(Get FASTA)	NCBI Sequence Viewer
	XP_063125373	(Get FASTA)	NCBI Sequence Viewer
	XP_063125374	(Get FASTA)	NCBI Sequence Viewer
	XP_063125375	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI29119	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005879
	ENSRNOP00000005879.7
	ENSRNOP00000108628.1

RefSeq Acc Id:	XP_006245944 ⟸ XM_006245882
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLPEPSEQEGESLRAGQEPSRGARKPQESSSLVPARDKEKPKPTDVMSQETSSTTTLPNNTLQ ALPAKKQGRIIHRKRSRVDAVAPQPLEFLKTPSGSRLLVHKSFLYKQEKAVGDKVYWKCRQHSE LGCRGRAITRGFRVTEMRDHCHPPEKEGLGKKRRQKEKLPSSGTEGQGDGVSLWLYPVEPEPTP QPSIETPEEEQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGS KVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLE DCDDIEDTLLQGVDSLFYRRGPGTLTLSRSRSRKRAKKQQEPLQESPEEEDQDVDPKGPEFLKT PLGGNFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLET LRQRQKRPGPAQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGDKVYWTCRDQARMGCRSRA ITQGQRVMVMRRHCHPPDMGGLEALRQRENFPNLTHWEGPEPVQPLEFLQTSLGGRFLVYESFL YRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHSPDLAGLEALRQREREKARERE KAREREKAPSAAKKKKKKKKKKGKSKS hide sequence

Ensembl Acc Id:

ENSRNOP00000005879 ⟸ ENSRNOT00000005879

RefSeq Acc Id:	XP_038943004 ⟸ XM_039087076
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385721 ⟸ NM_001398792
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125372 ⟸ XM_063269302
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125375 ⟸ XM_063269305
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125371 ⟸ XM_063269301
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125373 ⟸ XM_063269303
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125369 ⟸ XM_063269299
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125370 ⟸ XM_063269300
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125374 ⟸ XM_063269304
- Peptide Label:	isoform X1
- UniProtKB:	F7FDF2 (UniProtKB/TrEMBL), A1L1L4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000108628 ⟸ ENSRNOT00000134358

Protein Domains

FLYWCH-type FLYWCH-type zinc finger-containing protein N-

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F7FDF2-F1-model_v2	AlphaFold	F7FDF2	1-667	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697007

Promoter ID:

EPDNEW_R7521

Type:

initiation region

Name:

Flywch1_1

Description:

FLYWCH-type zinc finger 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	13,107,788 - 13,107,848	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309385	AgrOrtholog
BioCyc Gene	G2FUF-25906	BioCyc
Ensembl Genes	ENSRNOG00000004333	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005879	ENTREZGENE
	ENSRNOT00000005879.9	UniProtKB/TrEMBL
	ENSRNOT00000134358.1	UniProtKB/TrEMBL
Gene3D-CATH	2.20.25.240	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7114597	IMAGE-MGC_LOAD
InterPro	FLYWCH_N	UniProtKB/TrEMBL
	FWCH1/FWCH2	UniProtKB/TrEMBL
	Znf_FLYWCH	UniProtKB/TrEMBL
MGC_CLONE	MGC:156766	IMAGE-MGC_LOAD
NCBI Gene	360488	ENTREZGENE
PANTHER	FLYWCH-TYPE ZINC FINGER-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	PTHR31665	UniProtKB/TrEMBL
Pfam	FLYWCH	UniProtKB/TrEMBL
	FLYWCH_N	UniProtKB/TrEMBL
	FLYWCH_u	UniProtKB/TrEMBL
PhenoGen	Flywch1	PhenoGen
RatGTEx	ENSRNOG00000004333	RatGTEx
UniProt	A0ABK0LD31_RAT	UniProtKB/TrEMBL
	A1L1L4	ENTREZGENE, UniProtKB/TrEMBL
	F7FDF2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-26	Flywch1	FLYWCH-type zinc finger 1	RGD1309385_predicted	similar to RIKEN cDNA E030034P13 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1309385_predicted	similar to RIKEN cDNA E030034P13 (predicted)	LOC360488_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC360488_predicted	similar to RIKEN cDNA E030034P13 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar