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Gene: Unc119b (unc-119 lipid binding chaperone B) Rattus norvegicus

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Symbol:

Unc119b (Ensembl: Mlec)

Name:

unc-119 lipid binding chaperone B (Ensembl:malectin)

RGD ID:

1309359

Description:

Predicted to enable lipid binding activity. Predicted to be involved in cilium assembly; lipoprotein transport; and nervous system development. Predicted to be located in ciliary transition zone. Predicted to be active in cilium. Orthologous to human UNC119B (unc-119 lipid binding chaperone B); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC288702; RGD1309359; similar to Unc-119 protein homolog (Retinal protein 4) (RRG4); unc-119 homolog B; unc-119 homolog B (C. elegans)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UNC119B (unc-119 lipid binding chaperone B)	HGNC	HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Unc119b (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Unc119b (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UNC119B (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UNC119B (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Unc119b (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UNC119B (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UNC119B (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Unc119b (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Unc119b (unc-119 lipid binding chaperone B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MLEC (malectin)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Unc119b (unc-119 lipid binding chaperone B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	UNC119B (unc-119 lipid binding chaperone B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	UNC119B (unc-119 lipid binding chaperone B)	Alliance	DIOPT (HGNC)
Danio rerio (zebrafish):	unc119.1 (unc-119 homolog 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-119	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	unc-119	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	unc119b	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	unc119b	Alliance	DIOPT (OMA\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	47,139,492 - 47,152,115 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	47,139,545 - 47,152,112 (+)	Ensembl				GRCr8
mRatBN7.2	12	41,478,808 - 41,491,432 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,478,808 - 41,491,432 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	42,646,301 - 42,658,923 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	43,259,958 - 43,272,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	42,320,523 - 42,333,145 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	47,239,663 - 47,252,286 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	47,218,969 - 47,252,286 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	49,034,761 - 49,047,383 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	42,750,444 - 42,763,067 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	43,097,509 - 43,110,154 (+)	NCBI		Celera
RGSC_v3.1	12	42,613,896 - 42,623,617 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

chlorpyrifos (ISO)

clothianidin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diuron (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

gentamycin (EXP)

leflunomide (ISO)

methidathion (ISO)

nitrates (ISO)

okadaic acid (ISO)

phenobarbital (ISO)

propiconazole (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

tributylstannane (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell projection organization (IEA)

cilium assembly (IBA,IEA,ISO)

lipoprotein transport (IBA,IEA,ISO)

nervous system development (IBA)

protein transport (IEA)

Cellular Component

ciliary transition zone (IEA,ISO)

cilium (IBA)

sperm end piece (IEA,ISO)

sperm midpiece (IEA,ISO)

sperm principal piece (IEA,ISO)

Molecular Function

lipid binding (IBA,IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22085962

Genomics

Comparative Map Data

Unc119b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	47,139,492 - 47,152,115 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	47,139,545 - 47,152,112 (+)	Ensembl				GRCr8
mRatBN7.2	12	41,478,808 - 41,491,432 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,478,808 - 41,491,432 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	42,646,301 - 42,658,923 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	43,259,958 - 43,272,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	42,320,523 - 42,333,145 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	47,239,663 - 47,252,286 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	47,218,969 - 47,252,286 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	49,034,761 - 49,047,383 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	42,750,444 - 42,763,067 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	43,097,509 - 43,110,154 (+)	NCBI		Celera
RGSC_v3.1	12	42,613,896 - 42,623,617 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

UNC119B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	120,710,458 - 120,723,640 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	120,710,440 - 120,723,640 (+)	Ensembl			hg38	GRCh38
GRCh37	12	121,148,261 - 121,161,443 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	119,632,214 - 119,645,826 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	120,782,096 - 120,795,706 (+)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	118,157,594 - 118,170,796 (+)	NCBI		HuRef
CHM1_1	12	121,117,014 - 121,130,218 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	120,699,614 - 120,712,778 (+)	NCBI		T2T-CHM13v2.0

Unc119b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	115,260,625 - 115,273,034 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	115,260,609 - 115,273,034 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	115,122,566 - 115,134,975 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	115,122,550 - 115,134,975 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	115,572,575 - 115,584,984 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	115,383,565 - 115,395,974 (-)	NCBI		MGSCv36	mm8
Celera	5	112,218,822 - 112,231,256 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.99	NCBI

Unc119b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	10,950,126 - 10,963,803 (-)	Ensembl
ChiLan1.0	NW_004955455	10,950,126 - 10,963,803 (-)	NCBI	ChiLan1.0	ChiLan1.0

UNC119B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	128,780,704 - 128,793,897 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	128,777,077 - 128,790,270 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	118,293,984 - 118,307,156 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	121,667,039 - 121,679,936 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	121,667,064 - 121,676,321 (+)	Ensembl			panPan2	panpan1.1

UNC119B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	16,557,721 - 16,569,695 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	16,557,742 - 16,566,257 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	16,560,262 - 16,572,241 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	16,823,682 - 16,835,670 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	16,823,673 - 16,835,670 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	16,784,230 - 16,796,212 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	16,859,974 - 16,871,944 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	16,902,310 - 16,914,299 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Unc119b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	145,776,684 - 145,797,693 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936668	275,512 - 289,971 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936668	275,573 - 289,938 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UNC119B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	40,627,730 - 40,638,493 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	40,624,196 - 40,638,497 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	43,091,946 - 43,106,246 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UNC119B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	116,067,717 - 116,081,164 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	116,067,753 - 116,081,437 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	129,015,734 - 129,029,306 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Unc119b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	12,975,298 - 12,988,912 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	12,974,046 - 12,988,927 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Unc119b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	38,690,044 - 38,699,661 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	847
Count of miRNA genes:	314
Interacting mature miRNAs:	407
Transcripts:	ENSRNOT00000001553
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	44139558	52308831	Rat

Markers in Region

RH130093

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	41,491,237 - 41,491,421 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	47,252,092 - 47,252,275	NCBI	Rnor6.0
Rnor_5.0	12	49,047,189 - 49,047,372	UniSTS	Rnor5.0
RGSC_v3.4	12	42,762,873 - 42,763,056	UniSTS	RGSC3.4
Celera	12	43,109,960 - 43,110,143	UniSTS
Cytogenetic Map	12	q16	UniSTS

RH141829

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	41,488,631 - 41,488,827 (+)	MAPPER	mRatBN7.2
mRatBN7.2	12	41,488,631 - 41,488,931 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	47,249,486 - 47,249,785	NCBI	Rnor6.0
Rnor_6.0	12	47,249,486 - 47,249,681	NCBI	Rnor6.0
Rnor_5.0	12	49,044,583 - 49,044,882	UniSTS	Rnor5.0
Rnor_5.0	12	49,044,583 - 49,044,778	UniSTS	Rnor5.0
RGSC_v3.4	12	42,760,267 - 42,760,566	UniSTS	RGSC3.4
RGSC_v3.4	12	42,760,267 - 42,760,462	UniSTS	RGSC3.4
Celera	12	43,107,354 - 43,107,549	UniSTS
Celera	12	43,107,354 - 43,107,653	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC105804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000077871 ⟹ ENSRNOP00000072503

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	47,139,545 - 47,152,112 (+)	Ensembl
mRatBN7.2 Ensembl	12	41,478,808 - 41,491,432 (+)	Ensembl

RefSeq Acc Id:

NM_001105934 ⟹ NP_001099404

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	47,139,492 - 47,152,115 (+)	NCBI
mRatBN7.2	12	41,478,808 - 41,491,432 (+)	NCBI
Rnor_6.0	12	47,239,663 - 47,252,286 (+)	NCBI
Rnor_5.0	12	49,034,761 - 49,047,383 (+)	NCBI
RGSC_v3.4	12	42,750,444 - 42,763,067 (+)	RGD
Celera	12	43,097,509 - 43,110,154 (+)	RGD

Sequence:

show sequence

GGGCCCCGCCCCCGCTCTCCATAGTTACGGCGCCCTGAGGTGGCGGCCATCTTGGCGGTGGAGC
GATGAGCGGGTCGAACCCGAAGGCTACGACCGCGGGGTCGCAGGCTGGGCCCGGCGGGCTGGTA
GCTGGCAAGGAGGAGAAGAAGAAGGCGGGCGGCGGCGTCCTGAACCGGCTTAAGGCGCGGCGGC
AGGGGCCGCCACACACGTCGGACGACGGCCCCGGGACCGCGGTCACGGAGCAGGAGCTGCTGGC
ACTGGACACGATCCGCCCTGAGCACGTCCTACGCCTCAACCGGGTCACCGAGAATTATTTATGT
AAACCCGAGGACAATGTCTACAGTATTGACTTTACCCGCTTCAAAATCCGAGATCTGGAGACAG
GGACGGTGCTCTTCGAGATTGCCAAACCTTGCATCTCAGACCAAGACCAGGACACAGAGGAGGA
GAGTGTGGACGTAGACATCAGCGTGGGGCGTTTCGTCCGCTATCAGTTCACGCCAGCGTTCCTC
CGCCTGCGGACCGTCGGTGCCACGGTAGAGTTCACCGTGGGCGACAGGCCGGTGACAGGCTTCC
GGATGATCGAGCGGCACTACTTCCGGGAGCGGCTACTGAAGACCTTTGACTTTGATTTCGGCTT
CTGCATCCCTAGCAGCAGAAACACGTGTGAGCACATCTATGAGTTCCCGCAGCTCTCAGAGGAC
GTCATCCGTCTGATGATCGAGAACCCCTATGAGACGCGCTCCGACAGCTTCTACTTTGTGGACA
ACAAGCTGATCATGCACAACAAGGCCGACTATGCCTATAACGGAGGCCAGTAAGCGCTGCACAG
TGGACGGGAGGTCCTCTGCTGCCACCACGAGGCTCACAGCGGAACTGCAGCTGCTGCCCGTCAA
CACCCACCTTGAACCTGGTCCAGGAGGCTGCATCTGGGGCGGTGATGGTTTGTGCTCCAAGGCG
GTGCCAGGCGGCAGTTTCTCTTCCCAGTGTTTGTTCTCTGCCCCTGGTTCACAGAGGTTTACAG
TGAGGGAAAGATTAGGGTAAGGTTCCCGGATCCAGATAAAAGCTTATTTCTGTGTAGTCTTCCC
AGTGTTTGTTCCCTGCCCCTGGTTCACGGAGGCTTTACAGTGAGGTAAAGATTAGGGTAAGGTT
CCCAGATCCAGATAAAAGCTTATTTCTGTGTAGTCTTAGCCGTGCACTGCTTATCCCGACAAGC
CTGCCGGTCCAGGCACAGCTGTGTCAGCCAGAAGGCTTGGGCTGGGCCGGCCCGCAGGTTACCA
GCCCTCTGCAGGCTCCTGGATGCTGTGGGCAGCTGAGAGCGGCTCACTTCTCCCTCATCCTGTG
TCCTCGCTATGCAGTTAGGCCAACTGGAAGAAACTTGAAGAGAGACTCTGGTAGGGCGGAGCCC
AAGCTAAGGCACTGGGCTGGAAGGTCAAAGACAAAGTTTTTGAGGAGGCTTCTTACCTGCCTTT
GAGAAGCCACATCCAGGCCTCGGGGAGCCACAGTCTCAGCCTGACGGCACCCTCTGTTCTTGCT
CTAGAAGCCGTGAGCTGCTCTGCTCTCCTGGCTGTGACCTTAACATGTCCTGCTGTGGCCCTTG
TCAGTTTTGTTCACAGAACGTGGTGTCGCTCTAGTTCAGTGCAGGCGGGTTGTGCTTTGTGCTC
CTTATTCTCAGACTTCTTTGGGGAATTTTACAGTGTCAGTGTTTAGTGCCCAGGAGGCCGATAG
ATCTCCGATAGGACTGATTGGCTAATGGGGCTCCTGTGGGAAGGCACAGTCGAGCTTTAGAGAG
AGAGCTGACTGTACAGTGAGCCTGCAGGAGGCTCTGAGTGGGGATTTGGCTCCAGAGCAGAGGC
TCGTGTTTAGGAAGACTTTCCTACTGTTTGCCTTCCTTCCGCTGAAGTCCTTCCTCGAACCATC
TGCCACAGCATGGTCCTGAGGAATGACCAGTCTGACCTGCTGTCAAATTGATGCATGTTTGGGT
TTGGGAAGGGGCAGCATAGGCTTCCTACACTTGTGGGCCTCAGGTGTCCTCAGTTCCCCACTGA
CCGACTCCCACCTCTTTGGCTCCCTTGGTTGTCCCTGTGGGTGGCTCTAGGACTCTGCTTGGCT
GGGGTCTATTTGGCATTGAATGAGGTGCAGGAGGGGCGCGTGTGCATAAAGTGTCTCTGCGGCA
CCACATCACCTGTTATGTCACCTGTGACACGACCAGGGCCCCAAAGCAAAAGGACTTGCTTTGT
CCAGTGTCGCTCTGCTGGCCTCTAAAGCATTAGTGGGCTTGGATTTGGACCCTTATTCTATGTC
TGGCCAGCACCTGATGGCCACGTGTGGGCAGCGTTGGGAATGAGGAAGCCTGGCTCACCCTTCA
TGCTGCACTGGATTTATCCACTGAGATAAGCGAGCCCAGGTGACCATTCCAGTGATCTCAGAGC
TGGAGTCCACTCCAAATCTAGTGCCTTAAGTGTGGCTCTGCCCTATGTGCTGCTGGGAGCTGCG
GGGCCATTGTCCTCCCTTTCCTATATACAGACATGAGCAGTCTCTGCTTTCCCTCACCCGGCTC
CTCTGGTGAGATTTCCATGTTCTTGACAAGCTTCAGAGCCCTTGCCCTGTTCCAGTCTGGTGAG
GTATTTGGTTCCCAGTGAGTGAGTGAGAACTACCAGGATGTGCTTCCTGGGGCTGCGTGAGCTT
TGCTCAGTGGAGCGCAGCCTGGGCTGCTCCTGTTTCCTGGCACTGTTTCCTGCCCGTCGTGCTG
GCTTTTACTTGGAGAGTCCCGGGTGGAGGAGCTGGGCACACTGGCTTGAGACGGGTGGCAGCCT
CTTGCTCACCAGCCTGTTCTCAGTGAGCGCACACTGAGGCCGGTGCTCAGTCAGCCTGCTAGGA
TGGAGCAGTCTCCTTAGCTCCTGAAGGGCCAGGAATCCCTGTCTGGCTGCGAACGGATGCATCT
GCTCTTTGCTAGAGAGTTTGAAATCCCGGCTTTTGTGCCTGACTTGAGGAAACTGGAAGTCCTC
TTGGTGAACGACTGACAGCAGAGGCATGTGCAGGAGCCCCAGTGGTTAGAGCAGCTTCCTGTGA
CACCGAGGGAGACAGAGTCAGTGCTGGGGGCGCATGCCCCTTGCCCAGAGCAGCCCCAGGGGAC
CTCCCCGCAGCTGGGCAGAAGCCCCCCTGGTACGAGGCAGGTTCTGCTTGGTCTCTATCCTTGG
CCTATGCCTTGGGGCCAAGCTGCCTAAACCATGAACACAGGAGTAAAGATAGCCAGTACCTGGG
CTGGTGTCAGCTGTTGTCTCAGCTCAGCTCAGCACTGTCTCGTACGAACCTTCTGAAGCTTCTC
TAGGCTCTGGGCATCTGATTCCCAGTTCCTGGGGACAGCACCTTGTTGTGTCCGGGATGGGCCA
TAGACTCAGATTCTGAAAACATCCACATTCCGTGTCCAGAGCATCATAGCCAGGGAGTCTGGAA
GAGGTGGGCTCACCCTTGTTTCATAAAGGATCATGTGGTGATGTCCCTCGAGTTGTGAAAGTCT
ATTTTCCCTGTAAATCTATTTTTCACAGAATTTTAGAAACATCTCTGTCCTTAAAATCCTCATT
TCAAAAACCTAGGTGATTCTATTTGTATGAGATGCTATTTTACCACCAGAGACGGTAATAAAGA
TTTTTCACAAT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099404	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13906	(Get FASTA)	NCBI Sequence Viewer
	EDM13907	(Get FASTA)	NCBI Sequence Viewer
	EDM13908	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072503
	ENSRNOP00000072503.2

RefSeq Acc Id:

NP_001099404 ⟸ NM_001105934

- UniProtKB:

A0A0G2K351 (UniProtKB/TrEMBL), A6J1W7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGSNPKATTAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTSDDGPGTAVTEQELLA
LDTIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQDTEEE
SVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGF
CIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000072503 ⟸ ENSRNOT00000077871

Protein Domains

GMP phosphodiesterase delta subunit

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698700

Promoter ID:

EPDNEW_R9225

Type:

initiation region

Name:

Mlec_1

Description:

malectin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R9224

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	47,239,711 - 47,239,771	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309359	AgrOrtholog
BioCyc Gene	G2FUF-18973	BioCyc
Ensembl Genes	ENSRNOG00000021725	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000077871	ENTREZGENE
	ENSRNOT00000077871.3	UniProtKB/TrEMBL
Gene3D-CATH	2.70.50.40	UniProtKB/TrEMBL
InterPro	GMP_PDE_delta	UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/TrEMBL
	PDE6D_unc-119_myristoyl-bd	UniProtKB/TrEMBL
	PDED_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:288702	UniProtKB/TrEMBL
NCBI Gene	288702	ENTREZGENE
PANTHER	PROTEIN UNC-119 HOMOLOG B	UniProtKB/TrEMBL
	RETINAL PROTEIN 4	UniProtKB/TrEMBL
Pfam	GMP_PDE_delta	UniProtKB/TrEMBL
PhenoGen	Unc119b	PhenoGen
RatGTEx	ENSRNOG00000021725	RatGTEx
Superfamily-SCOP	Ig_E-set	UniProtKB/TrEMBL
UniProt	A0A0G2K351	ENTREZGENE, UniProtKB/TrEMBL
	A6J1W7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-26	Unc119b	unc-119 lipid binding chaperone B	Unc119b	unc-119 homolog B (C. elegans)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-26	Unc119b	unc-119 homolog B (C. elegans)	RGD1309359_predicted	similar to Unc-119 protein homolog (Retinal protein 4) (RRG4) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1309359_predicted	similar to Unc-119 protein homolog (Retinal protein 4) (RRG4) (predicted)	LOC288702_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC288702_predicted	similar to Unc-119 protein homolog (Retinal protein 4) (RRG4) (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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