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Gene: Ncln (nicalin) Rattus norvegicus

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Symbol:

Ncln

Name:

nicalin

RGD ID:

1309355

Description:

Predicted to enable ribosome binding activity. Predicted to be involved in several processes, including multi-pass transmembrane protein insertion into ER membrane; protein stabilization; and regulation of protein complex stability. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of multi-pass translocon complex. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human NCLN (nicalin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

BOS complex subunit NCLN; LOC314648; nicalin homolog; nicalin homolog (zebrafish); nicastrin-like protein; RGD1309355; similar to hypothetical protein from EUROIMAGE 2021883

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NCLN (nicalin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ncln (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ncln (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NCLN (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NCLN (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ncln (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NCLN (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NCLN (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ncln (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ncln (nicalin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RELT (RELT TNF receptor)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NCLN (nicalin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ncln (nicalin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nra-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4972	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ncln	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ncln	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ncln	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	8,862,324 - 8,872,699 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	8,862,751 - 8,872,698 (+)	Ensembl				GRCr8
mRatBN7.2	7	8,211,978 - 8,221,938 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	8,211,996 - 8,221,934 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	11,098,042 - 11,107,974 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	12,973,525 - 12,983,457 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	10,840,645 - 10,850,578 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	11,081,544 - 11,091,583 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,081,536 - 11,091,584 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	11,248,733 - 11,258,772 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	9,695,951 - 9,705,989 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	6,402,537 - 6,412,474 (+)	NCBI		Celera
RGSC_v3.1	7	9,695,950 - 9,705,988 (+)	NCBI
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hirschsprung's disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (EXP,ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

cisplatin (ISO)

clobetasol (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

dimethyl sulfoxide (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

eugenol (EXP)

fulvestrant (ISO)

ivermectin (ISO)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

miconazole (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

multi-pass transmembrane protein insertion into ER membrane (IEA,ISO,ISS)

protein stabilization (IEA,ISO)

regulation of protein complex stability (IEA,ISO)

regulation of protein-containing complex assembly (IEA,ISO)

regulation of signal transduction (IBA,IEA)

Cellular Component

endoplasmic reticulum membrane (IBA,IEA,ISO)

membrane (IEA)

multi-pass translocon complex (IEA,ISO,ISS)

protein-containing complex (IEA,ISO)

Molecular Function

protein binding (ISO)

ribosome binding (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:19946888	PMID:20538592

Genomics

Comparative Map Data

Ncln
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	8,862,324 - 8,872,699 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	8,862,751 - 8,872,698 (+)	Ensembl				GRCr8
mRatBN7.2	7	8,211,978 - 8,221,938 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	8,211,996 - 8,221,934 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	11,098,042 - 11,107,974 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	12,973,525 - 12,983,457 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	10,840,645 - 10,850,578 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	11,081,544 - 11,091,583 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,081,536 - 11,091,584 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	11,248,733 - 11,258,772 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	9,695,951 - 9,705,989 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	6,402,537 - 6,412,474 (+)	NCBI		Celera
RGSC_v3.1	7	9,695,950 - 9,705,988 (+)	NCBI
Cytogenetic Map	7	q11	NCBI

NCLN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	3,185,930 - 3,209,575 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	3,185,563 - 3,209,575 (+)	Ensembl			hg38	GRCh38
GRCh37	19	3,185,928 - 3,209,573 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	3,136,875 - 3,160,573 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	3,136,874 - 3,160,572	NCBI
Celera	19	3,122,250 - 3,145,978 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	2,952,961 - 2,976,782 (+)	NCBI		HuRef
CHM1_1	19	3,184,524 - 3,208,222 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	3,160,750 - 3,184,441 (+)	NCBI		T2T-CHM13v2.0

Ncln
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	81,322,289 - 81,333,178 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	81,322,083 - 81,332,226 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	81,486,455 - 81,496,954 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,486,249 - 81,496,392 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	80,949,204 - 80,959,108 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,889,378 - 80,899,485 (-)	NCBI		MGSCv36	mm8
Celera	10	82,509,842 - 82,519,746 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Ncln
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	5,222,808 - 5,238,643 (-)	Ensembl
ChiLan1.0	NW_004955495	5,222,990 - 5,238,644 (-)	NCBI	ChiLan1.0	ChiLan1.0

NCLN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	7,581,716 - 7,605,672 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	6,815,021 - 6,838,924 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	2,211,474 - 2,235,691 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	3,166,042 - 3,189,681 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	3,166,042 - 3,189,681 (+)	Ensembl			panPan2	panpan1.1

NCLN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	56,088,017 - 56,104,723 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	56,088,017 - 56,104,723 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	55,811,878 - 55,828,580 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	56,746,690 - 56,763,396 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	56,745,969 - 56,763,411 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	55,802,155 - 55,818,810 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	56,286,144 - 56,302,913 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	56,484,881 - 56,501,641 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ncln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	215,994,392 - 216,008,251 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,826,045 - 1,840,411 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	1,826,065 - 1,840,391 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NCLN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	75,369,955 - 75,390,545 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	75,369,926 - 75,390,609 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	75,891,204 - 75,909,206 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NCLN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	2,948,723 - 2,975,465 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	2,948,212 - 2,975,596 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666081	5,608,300 - 5,633,124 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ncln
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,018,439 - 6,035,446 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624828	6,018,438 - 6,035,310 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ncln
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	153,392,652 - 153,402,736 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ncln
47 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	159
Count of miRNA genes:	107
Interacting mature miRNAs:	130
Transcripts:	ENSRNOT00000007110
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1669658	46669658	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	1	23748937	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	1	31777942	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1709527	46709527	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	32612984	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	29716167	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34650782	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	32612984	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FB794080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FB826799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB664139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB696858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007110 ⟹ ENSRNOP00000007110

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	8,862,766 - 8,872,698 (+)	Ensembl
mRatBN7.2 Ensembl	7	8,211,996 - 8,221,934 (+)	Ensembl
Rnor_6.0 Ensembl	7	11,081,536 - 11,091,584 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094550 ⟹ ENSRNOP00000077163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	8,862,751 - 8,872,696 (+)	Ensembl
mRatBN7.2 Ensembl	7	8,211,996 - 8,221,934 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106364 ⟹ ENSRNOP00000088639

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	8,862,751 - 8,872,696 (+)	Ensembl
mRatBN7.2 Ensembl	7	8,211,996 - 8,221,934 (+)	Ensembl

RefSeq Acc Id:

NM_001014082 ⟹ NP_001014104

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	8,862,770 - 8,872,699 (+)	NCBI
mRatBN7.2	7	8,212,009 - 8,221,938 (+)	NCBI
Rnor_6.0	7	11,081,653 - 11,091,582 (+)	NCBI
Rnor_5.0	7	11,248,733 - 11,258,772 (+)	NCBI
RGSC_v3.4	7	9,695,951 - 9,705,989 (+)	RGD
Celera	7	6,402,537 - 6,412,474 (+)	RGD

Sequence:

show sequence

TGCTGAGCTGAGTCCGCGGAACCGCGGTCGTTCCTTGTCGCCGTCCGCCGCCGCCGCCTTTGCG
GCCTGCCGCCCACCGGGATGCTGGAGGAAGCGGGCGAGGTGCTCGAGAACGTGCTGAAGGCGTC
GTGCCTGCCGCTCGGCTTTATCGTCTTCTTGCCCGCTGTGCTGCTGCTCGTGGCGCCGCCGCTG
CCCGCCGCCGACGCCGCGCACGAGTTCACCGTGTACCGCATGCAGCAGTACGACCTGCAGGGCC
AGCCATACGGCACACGGAATGCTGTACTCAACACAGAGGCGCGCACAGTGGACGCGGATGTGCT
GAGCCGCCGCTGCGTGCTCATGCGGCTCCTGGATTTTTCCTATGAGCACTATCAGAAGGCCCTG
CGGCAGTCGGCAGGTGCTGTGGTCATCATCCTGCCCCGTGCCATGGCTGCGGTGCCTCAGGATG
TTGTACGGCAATTCATGGAGATCGAGCCTGAGATGCTGGCCATGGAGACTGTGGTCCCCGTGTA
CTTTGCTGTGGAGGATGAGGCCCTGCTGTCCATCTATGAGCAGACCCAGGCTGCCTCTGCCTCC
CAGGGCTCTGCCTCTGCGGCCGAAGTACTGCTGCACACAGCCACAGCCAATGGCTTCCAGATGG
TGACCAGTGGAGCCCAGAGCCAGGCAGTGAGTGACTGGCTCATCACCAGTGTGGAGGGGCGGCT
GACAGGGCTGGGAGGGGAGGACCTCCCCACCATCGTCATCGTAGCTCACTACGACGCCTTTGGG
GTAGCTCCATGGCTGTCACTGGGTGCAGACTCGAACGGGAGTGGCATCTCTGTACTGCTGGAGC
TGGCTCGCCTCTTCTCACGCCTCTACACGTACAAGCGCACTCATGCAGCGTACAACCTTCTGTT
CTTCGCATCTGGAGGGGGCAAGTTCAACTACCAGGGCACCAAGCGCTGGCTTGAGGACAGCCTG
GATCACACAGACTCCAGCCTCCTGCAGGACAACGTAGCCTTTGTTCTATGCCTGGACACCGTGG
GACGTGGCAGCCACCTGCGGCTGCATGTGTCCAAGCCTCCGCGGGAGGGGACACTGCAGCATGT
CTTCCTGCGCGAGCTGGAGATGGTGGCTGCGCACCAGTTCCCTGACGTCAGCTTCTCCATGGTA
CACAAGAAAATCAATCTAGCAGATGACGTGCTGGCCTGGGAGCATGAGCGCTTTGCCATCCGGA
GGCTGCCCGCCTTCACGCTGTCCCATCTGGAGAACCACCGCGCAGGGCCCCGCAGCAGCATCAT
GGATGTGCGGTCCCGGGTGGACTCCAAGACCCTGACTCGGAACACAAGGATCATCGCTGAGGCC
CTAACAAGGGTCATCTACAACCTGACAGAGAAGGGGACGCCCCCAGACATGCCAGTGTTCACGG
AGCAGATGCAGGTCCAGCAGGAGCAGATAGACTCAGTCATGGACTGGCTCACCAACCAGCCCCG
GGCCGCCCAACTGCTGGACAAGGACGGGACGTTCCTGAGTACACTGGAGCACTTCCTGAGCCGC
TACCTGAAGGACGTGCGGCAGCACCACGTGAAGGCCGACAAGCGGGACCCTGAGTTTGTCTTCT
ATGACCAGCTGAAGCAAGTGATGAACGCTTACAGGGTCAAGCCAGCCATCTTTGACCTGCTGCT
GGCCTTGTGCATTGGGGCGTACCTGGGCATGGCATACACAGCCGTCCAGCACTTCCATGTGCTG
TACAAGACGGTGCAGAGACTGCTGCTCAAGGCCAAGGCACAGTGACAGTGGCCATGCACAGGTG
GCCCAGGAGGTCCTAGCCCACGCACCCACAGCAGCCAGACTGAACCACAGAGGGTTTGGATGGG
TCACTAGGATGCAGGGACACCTCTCCCTGTCCATTTCTTTGTCCCTGGAGGAGAGCCCCGCCCG
CCTGCAGACGAGCCCACTGGGATGGAATGATGACCCGGGCCACATGCACTGAAGGGCCGCACAC
TGCTGTTGGCCTCCCCAGTGGCTGGGTCCCAGAAGCCTGTCTCTGCAGTTCCCCAGAGGCAGCC
ACCGTCAGCCTGCCTCGCCCCAGCACTGGCCAGCACCCGACAATGTCTCCCTGATGCTCCTCCT
CATACCCCTGTCCCGCCTGTTGTCACCTCTGCCACCATTGAACCCACCTGGTCCCCCAGCTGGA
TCTGAGCCACCTGAGGTTCTGGCCCCTCCTGCAAGCGTCCCTTCGCTCAGTCCCAGTGCTGGTG
ACTGAGCAGGAGTTGGCCCTGGTCTGGAGTGTGTGCAGTTCTGAGGTCTCCCCACCTTCTACAC
TGCCCCCCCAGCCTCAGTTTCCCTACCTGAGATACATTCTGGGAAGTCCAGTCCTCTGTCATAG
TGTCTGATGGGACAACCAGGCCTAGCACAGCCCTGGATGTCCCCAACAGGATGGCCTTGGGAGG
GGGACACCGGTGCTGATGGTTGACCTCAGGGACCCCACAGTGAATTGATTCAATTGATTCAATA
GCAATATGACCCAGGAGGTGTCAGGCGGGGCAGCGGAGGCCATCTGAAGACCAGCTGCTTGCAT
CCCTCTAGCACCTGCTGAGGCCTGGCTCCCCCCACCCACCGTAGGCTGCCTCGGTTCAGCAGTG
GTGGCTGCCACCCTGGTGGCACTCGTGTCATAGGACGAGGGGGGTCAGCCTCCTGCCCTGGCCC
TGGGCACTCTCGTTCCCCTCACTACTCTTAACCTGGCAGCTGGTTACGGGTCTGAGGCCAGTGC
CACCTGCCACTGAAGAAGTACACAGGGCATGTGCCACCTCCCTCTGTCCCGATGGGTCATGGGG
ATGGATTGGCCCCTTGGGGTGGCCGTGGGTCTGCAGTTGGTGGGTTACAAAATAAAAGCCATAT
TGAAGGACCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006240943 ⟹ XP_006241005

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	8,862,324 - 8,872,699 (+)	NCBI
mRatBN7.2	7	8,211,978 - 8,221,874 (+)	NCBI
Rnor_6.0	7	11,081,544 - 11,091,583 (+)	NCBI
Rnor_5.0	7	11,248,733 - 11,258,772 (+)	NCBI

Sequence:

show sequence

TCCCGAAAAGCGATGCGGCAGACAGGGACGTCCGCAGCGCTGCCCGAAGGACCCTAGGGCAGGC
GCGGGTTATCCGTGGTTCTGCCCGAAGGACCTCAGCAGCCGCCCATGCTGAGCTGAGTCCGCGG
AACCGCGGTCGTTCCTTGTCGCCGTCCGCCGCCGCCGCCTTTGCGGCCTGCCGCCCACCGGGAT
GCTGGAGGAAGCGGGCGAGGTGCTCGAGAACGTGCTGAAGGCGTCGTGCCTGCCGCTCGGCTTT
ATCGTCTTCTTGCCCGCTGTGCTGCTGCTCGTGGCGCCGCCGCTGCCCGCCGCCGACGCCGCGC
ACGAGTTCACCGTGTACCGCATGCAGCAGTACGACCTGCAGGGCCAGCCATACGGCACACGGAA
TGCTGTACTCAACACAGAGGCGCGCACAGTGGACGCGGATGTGCTGAGCCGCCGCTGCGTGCTC
ATGCGGCTCCTGGATTTTTCCTATGAGCACTATCAGAAGGCCCTGCGGCAGTCGGCAGGTGCTG
TGGTCATCATCCTGCCCCGTGCCATGGCTGCGGTGCCTCAGGATGTTGTACGGCAATTCATGGA
GATCGAGCCTGAGATGCTGGCCATGGAGACTGTGGTCCCCGTGTACTTTGCTGTGGAGGATGAG
GCCCTGCTGTCCATCTATGAGCAGACCCAGGCTGCCTCTGCCTCCCAGGGCTCTGCCTCTGCGG
CCGAAGTACTGCTGCACACAGCCACAGCCAATGGCTTCCAGATGGTGACCAGTGGAGCCCAGAG
CCAGGCAGTGAGTGACTGGCTCATCACCAGTGTGGAGGGGCGGCTGACAGGGCTGGGAGGGGAG
GACCTCCCCACCATCGTCATCGTAGCTCACTACGACGCCTTTGGGGTAGCTCCATGGCTGTCAC
TGGGTGCAGACTCGAACGGGAGTGGCATCTCTGTACTGCTGGAGCTGGCTCGCCTCTTCTCACG
CCTCTACACGTACAAGCGCACTCATGCAGCGTACAACCTTCTGTTCTTCGCATCTGGAGGGGGC
AAGTTCAACTACCAGGGCACCAAGCGCTGGCTTGAGGACAGCCTGGATCACACAGACTCCAGCC
TCCTGCAGGACAACGTAGCCTTTGTTCTATGCCTGGACACCGTGGGACGTGGCAGCCACCTGCG
GCTGCATGTGTCCAAGCCTCCGCGGGAGGGGACACTGCAGCATGTCTTCCTGCGCGAGCTGGAG
ATGGTGGCTGCGCACCAGTTCCCTGACGTCAGCTTCTCCATGGTACACAAGAAAATCAATCTAG
CAGATGACGTGCTGGCCTGGGAGCATGAGCGCTTTGCCATCCGGAGGCTGCCCGCCTTCACGCT
GTCCCATCTGGAGAACCACCGCGCAGGGCCCCGCAGCAGCATCATGGATGTGCGGTCCCGGGTG
GACTCCAAGACCCTGACTCGGAACACAAGGATCATCGCTGAGGCCCTAACAAGGGTCATCTACA
ACCTGACAGAGAAGGGGACGCCCCCAGACATGCCAGTGTTCACGGAGCAGATGGTCCAGCAGGA
GCAGATAGACTCAGTCATGGACTGGCTCACCAACCAGCCCCGGGCCGCCCAACTGCTGGACAAG
GACGGGACGTTCCTGAGTACACTGGAGCACTTCCTGAGCCGCTACCTGAAGGACGTGCGGCAGC
ACCACGTGAAGGCCGACAAGCGGGACCCTGAGTTTGTCTTCTATGACCAGCTGAAGCAAGTGAT
GAACGCTTACAGGGTCAAGCCAGCCATCTTTGACCTGCTGCTGGCCTTGTGCATTGGGGCGTAC
CTGGGCATGGCATACACAGCCGTCCAGCACTTCCATGTGCTGTACAAGACGGTGCAGAGACTGC
TGCTCAAGGCCAAGGCACAGTGACAGTGGCCATGCACAGGTGGCCCAGGAGGTCCTAGCCCACG
CACCCACAGCAGCCAGACTGAACCACAGAGGGTTTGGATGGGTCACTAGGATGCAGGGACACCT
CTCCCTGTCCATTTCTTTGTCCCTGGAGGAGAGCCCCGCCCGCCTGCAGACGAGCCCACTGGGA
TGGAATGATGACCCGGGCCACATGCACTGAAGGGCCGCACACTGCTGTTGGCCTCCCCAGTGGC
TGGGTCCCAGAAGCCTGTCTCTGCAGTTCCCCAGAGGCAGCCACCGTCAGCCTGCCTCGCCCCA
GCACTGGCCAGCACCCGACAATGTCTCCCTGATGCTCCTCCTCATACCCCTGTCCCGCCTGTTG
TCACCTCTGCCACCATTGAACCCACCTGGTCCCCCAGCTGGATCTGAGCCACCTGAGGTTCTGG
CCCCTCCTGCAAGCGTCCCTTCGCTCAGTCCCAGTGCTGGTGACTGAGCAGGAGTTGGCCCTGG
TCTGGAGTGTGTGCAGTTCTGAGGTCTCCCCACCTTCTACACTGCCCCCCCAGCCTCAGTTTCC
CTACCTGAGATACATTCTGGGAAGTCCAGTCCTCTGTCATAGTGTCTGATGGGACAACCAGGCC
TAGCACAGCCCTGGATGTCCCCAACAGGATGGCCTTGGGAGGGGGACACCGGTGCTGATGGTTG
ACCTCAGGGACCCCACAGTGAATTGATTCAATTGATTCAATAGCAATATGACCCAGGAGGTGTC
AGGCGGGGCAGCGGAGGCCATCTGAAGACCAGCTGCTTGCATCCCTCTAGCACCTGCTGAGGCC
TGGCTCCCCCCACCCACCGTAGGCTGCCTCGGTTCAGCAGTGGTGGCTGCCACCCTGGTGGCAC
TCGTGTCATAGGACGAGGGGGGTCAGCCTCCTGCCCTGGCCCTGGGCACTCTCGTTCCCCTCAC
TACTCTTAACCTGGCAGCTGGTTACGGGTCTGAGGCCAGTGCCACCTGCCACTGAAGAAGTACA
CAGGGCATGTGCCACCTCCCTCTGTCCCGATGGGTCATGGGGATGGATTGGCCCCTTGGGGTGG
CCGTGGGTCTGCAGTTGGTGGGTTACAAAATAAAAGCCATATTGAAGGACCGAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001014104	(Get FASTA)	NCBI Sequence Viewer
	XP_006241005	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83785	(Get FASTA)	NCBI Sequence Viewer
	CAW38768	(Get FASTA)	NCBI Sequence Viewer
	CAW54089	(Get FASTA)	NCBI Sequence Viewer
	CBC04640	(Get FASTA)	NCBI Sequence Viewer
	CBC26783	(Get FASTA)	NCBI Sequence Viewer
	EDL89145	(Get FASTA)	NCBI Sequence Viewer
	EDL89146	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000077163
GenBank Protein	Q5XIA1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001014104 ⟸ NM_001014082
- Peptide Label:	precursor
- UniProtKB:	Q5XIA1 (UniProtKB/Swiss-Prot), A6K875 (UniProtKB/TrEMBL), A6K876 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTR NAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFM EIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQGSASAAEVLLHTATANGFQMVTSGAQ SQAVSDWLITSVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFS RLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGRGSHL RLHVSKPPREGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFT LSHLENHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQ QEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQ VMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ hide sequence

RefSeq Acc Id:	XP_006241005 ⟸ XM_006240943
- Peptide Label:	isoform X1
- UniProtKB:	A0A0H2UHD9 (UniProtKB/TrEMBL), A6K876 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTR NAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFM EIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQGSASAAEVLLHTATANGFQMVTSGAQ SQAVSDWLITSVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFS RLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGRGSHL RLHVSKPPREGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFT LSHLENHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMVQQ EQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQV MNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ hide sequence

Ensembl Acc Id:

ENSRNOP00000007110 ⟸ ENSRNOT00000007110

Ensembl Acc Id:

ENSRNOP00000077163 ⟸ ENSRNOT00000094550

Ensembl Acc Id:

ENSRNOP00000088639 ⟸ ENSRNOT00000106364

Protein Domains

Peptidase M28

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIA1-F1-model_v2	AlphaFold	Q5XIA1	1-563	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694969

Promoter ID:

EPDNEW_R5494

Type:

initiation region

Name:

Ncln_1

Description:

nicalin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	11,081,641 - 11,081,701	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309355	AgrOrtholog
BioCyc Gene	G2FUF-35036	BioCyc
Ensembl Genes	ENSRNOG00000004793	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000094550	ENTREZGENE
Gene3D-CATH	Zn peptidases	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7096595	IMAGE-MGC_LOAD
InterPro	Nicalin	UniProtKB/Swiss-Prot
	Peptidase_M28	UniProtKB/Swiss-Prot
KEGG Report	rno:314648	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94760	IMAGE-MGC_LOAD
NCBI Gene	314648	ENTREZGENE
PANTHER	PTHR31826	UniProtKB/Swiss-Prot
Pfam	Peptidase_M28	UniProtKB/Swiss-Prot
PhenoGen	Ncln	PhenoGen
PIRSF	Nicalin	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004793	RatGTEx
Superfamily-SCOP	Zn-dependent exopeptidases	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHD9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5YC79_RAT	UniProtKB/TrEMBL
	A0A8I6AB62_RAT	UniProtKB/TrEMBL
	A6K875	ENTREZGENE, UniProtKB/TrEMBL
	A6K876	ENTREZGENE, UniProtKB/TrEMBL
	NCLN_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Ncln	nicalin	Ncln	nicalin homolog (zebrafish)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Ncln	nicalin homolog (zebrafish)	RGD1309355	similar to hypothetical protein from EUROIMAGE 2021883	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1309355	similar to hypothetical protein from EUROIMAGE 2021883	RGD1309355_predicted	similar to hypothetical protein from EUROIMAGE 2021883 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309355_predicted	similar to hypothetical protein from EUROIMAGE 2021883 (predicted)	LOC314648_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC314648_predicted	similar to hypothetical protein from EUROIMAGE 2021883 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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