Spred2 (sprouty-related, EVH1 domain containing 2) - Rat Genome Database

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Gene: Spred2 (sprouty-related, EVH1 domain containing 2) Rattus norvegicus
Analyze
Symbol: Spred2
Name: sprouty-related, EVH1 domain containing 2
RGD ID: 1309304
Description: Predicted to enable protein kinase binding activity; protein serine/threonine kinase inhibitor activity; and stem cell factor receptor binding activity. Predicted to be involved in negative regulation of cell differentiation and regulation of signal transduction. Predicted to act upstream of or within negative regulation of MAPK cascade. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305539; spred-2; sprouty-related, EVH1 domain-containing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,350,577 - 98,452,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1498,350,290 - 98,452,143 (+)EnsemblGRCr8
mRatBN7.21494,149,210 - 94,250,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,148,837 - 94,249,162 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1498,490,319 - 98,591,853 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01499,730,616 - 99,832,149 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,197,976 - 96,299,521 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,268,362 - 104,290,206 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,191,517 - 104,290,456 (+)Ensemblrn6Rnor6.0
Rnor_5.014104,002,472 - 104,024,316 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414100,775,869 - 100,797,717 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1493,246,801 - 93,268,145 (+)NCBICelera
RGSC_v3.114100,717,198 - 100,818,203 (+)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
atrazine  (EXP,ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
deguelin  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thifluzamide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytoplasmic vesicle  (IEA,ISO)
cytosol  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)
transport vesicle membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12646235   PMID:15580519   PMID:20736167   PMID:22305891   PMID:23982388   PMID:33124763   PMID:34406574  


Genomics

Comparative Map Data
Spred2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,350,577 - 98,452,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1498,350,290 - 98,452,143 (+)EnsemblGRCr8
mRatBN7.21494,149,210 - 94,250,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,148,837 - 94,249,162 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1498,490,319 - 98,591,853 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01499,730,616 - 99,832,149 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,197,976 - 96,299,521 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,268,362 - 104,290,206 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,191,517 - 104,290,456 (+)Ensemblrn6Rnor6.0
Rnor_5.014104,002,472 - 104,024,316 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414100,775,869 - 100,797,717 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1493,246,801 - 93,268,145 (+)NCBICelera
RGSC_v3.114100,717,198 - 100,818,203 (+)NCBI
Cytogenetic Map14q22NCBI
SPRED2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38265,307,175 - 65,432,599 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl265,310,851 - 65,432,637 (-)Ensemblhg38GRCh38
GRCh37265,537,985 - 65,659,733 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,391,489 - 65,512,815 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34265,449,636 - 65,570,961NCBI
Celera265,384,626 - 65,506,328 (-)NCBICelera
Cytogenetic Map2p14NCBI
HuRef265,272,227 - 65,393,668 (-)NCBIHuRef
CHM1_1265,469,340 - 65,590,964 (-)NCBICHM1_1
T2T-CHM13v2.0265,316,846 - 65,442,268 (-)NCBIT2T-CHM13v2.0
Spred2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391119,874,442 - 19,974,026 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1119,874,375 - 19,974,026 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381119,924,442 - 20,024,026 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1119,924,375 - 20,024,026 (+)Ensemblmm10GRCm38
MGSCv371119,824,445 - 19,922,600 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361119,824,445 - 19,922,600 (+)NCBIMGSCv36mm8
Celera1122,066,219 - 22,164,240 (+)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.79NCBI
Spred2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,133,568 - 19,250,118 (+)Ensembl
ChiLan1.0NW_00495542419,133,568 - 19,250,118 (+)NCBIChiLan1.0ChiLan1.0
SPRED2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21260,961,140 - 61,083,663 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A60,965,098 - 61,087,614 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,380,608 - 65,503,139 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,503,260 - 66,624,840 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,503,260 - 66,624,840 (-)EnsemblpanPan2panpan1.1
SPRED2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,764,275 - 64,815,937 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,764,311 - 64,867,009 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1064,648,640 - 64,763,412 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01065,771,737 - 65,886,366 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,773,399 - 65,886,224 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,450,264 - 65,564,843 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,758,109 - 65,872,866 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01066,053,709 - 66,168,347 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Spred2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,400,544 - 18,517,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649110,053,545 - 10,170,976 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649110,053,546 - 10,170,950 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPRED2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,523,589 - 76,649,651 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1376,527,646 - 76,649,652 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,324,906 - 80,445,715 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPRED2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,574,244 - 41,699,897 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1441,640,758 - 41,700,009 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604570,192,808 - 70,318,539 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spred2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,109,157 - 8,240,543 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247628,109,159 - 8,240,543 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Spred2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11188,183,040 - 88,289,730 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Spred2
571 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:46
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000006573
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)1496755448100078267Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 97 59 6 378 197 11 145 98 95 31 19 19

Sequence


Ensembl Acc Id: ENSRNOT00000006573   ⟹   ENSRNOP00000006573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,208,647 - 94,248,228 (+)Ensembl
Rnor_6.0 Ensembl14104,191,517 - 104,290,207 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079874   ⟹   ENSRNOP00000071793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1498,350,290 - 98,452,139 (+)Ensembl
mRatBN7.2 Ensembl1494,148,837 - 94,249,162 (+)Ensembl
Rnor_6.0 Ensembl14104,250,617 - 104,290,456 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161751   ⟹   ENSRNOP00000102473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1498,409,760 - 98,452,143 (+)Ensembl
RefSeq Acc Id: NM_001047094   ⟹   NP_001040559
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,350,577 - 98,452,143 (+)NCBI
mRatBN7.21494,149,210 - 94,250,787 (+)NCBI
Rnor_6.014104,268,362 - 104,290,206 (+)NCBI
Rnor_5.014104,002,472 - 104,024,316 (+)NCBI
RGSC_v3.414100,775,869 - 100,797,717 (+)RGD
Celera1493,246,801 - 93,268,145 (+)RGD
Sequence:
RefSeq Acc Id: XM_063273235   ⟹   XP_063129305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,391,314 - 98,452,140 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001040559 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129305 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE46587 (Get FASTA)   NCBI Sequence Viewer  
  EDL97928 (Get FASTA)   NCBI Sequence Viewer  
  EDL97929 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071793
  ENSRNOP00000071793.2
  ENSRNOP00000102473
GenBank Protein Q3C2P8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001040559   ⟸   NM_001047094
- UniProtKB: Q3C2P8 (UniProtKB/Swiss-Prot),   A6JQ11 (UniProtKB/TrEMBL),   A0A0G2K1D0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071793   ⟸   ENSRNOT00000079874
Ensembl Acc Id: ENSRNOP00000006573   ⟸   ENSRNOT00000006573
RefSeq Acc Id: XP_063129305   ⟸   XM_063273235
- Peptide Label: isoform X1
- UniProtKB: A0A8L2UHU3 (UniProtKB/TrEMBL),   A0A0G2K1D0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102473   ⟸   ENSRNOT00000161751
Protein Domains
KBD   SPR   WH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3C2P8-F1-model_v2 AlphaFold Q3C2P8 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309304 AgrOrtholog
BioCyc Gene G2FUF-14897 BioCyc
Ensembl Genes ENSRNOG00000004888 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000079874 ENTREZGENE
  ENSRNOT00000079874.2 UniProtKB/Swiss-Prot
  ENSRNOT00000161751 ENTREZGENE
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
InterPro KBD UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  SPRE_EVH1 UniProtKB/Swiss-Prot
  Sprouty UniProtKB/Swiss-Prot
  WH1/EVH1_dom UniProtKB/Swiss-Prot
KEGG Report rno:305539 UniProtKB/Swiss-Prot
NCBI Gene 305539 ENTREZGENE
PANTHER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam Sprouty UniProtKB/Swiss-Prot
  WH1 UniProtKB/Swiss-Prot
PhenoGen Spred2 PhenoGen
PROSITE KBD UniProtKB/Swiss-Prot
  SPR UniProtKB/Swiss-Prot
  WH1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004888 RatGTEx
SMART WH1 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
UniProt A0A0G2K1D0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UHU3 ENTREZGENE
  A0ABK0LCU8_RAT UniProtKB/TrEMBL
  A6JQ11 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ12_RAT UniProtKB/TrEMBL
  Q3C2P8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Spred2  sprouty-related, EVH1 domain containing 2  Spred2_predicted  sprouty-related, EVH1 domain containing 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Spred2_predicted  sprouty-related, EVH1 domain containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED