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Gene: Mmel1 (membrane metallo-endopeptidase-like 1) Rattus norvegicus

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Symbol:

Mmel1

Name:

membrane metallo-endopeptidase-like 1

RGD ID:

1309299

Description:

Enables metalloendopeptidase activity and zinc ion binding activity. Predicted to be involved in protein processing. Located in extracellular space. Orthologous to human MMEL1 (membrane metalloendopeptidase like 1); INTERACTS WITH 6-propyl-2-thiouracil; allethrin; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313755; mel transforming oncogene-like 1; Mell1; NEP2; NEP2(m); NEPII; neprilysin 2; neprilysin II; neprilysin-2; NL2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MMEL1 (membrane metalloendopeptidase like 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Mmel1 (membrane metallo-endopeptidase-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mmel1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MMEL1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MMEL1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mmel1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MMEL1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MMEL1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mmel1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mmel1 (membrane metalloendopeptidase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ADAM8 (ADAM metallopeptidase domain 8)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Mmel1 (membrane metallo-endopeptidase-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mmel1 (membrane metallo-endopeptidase-like 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MMEL1 (membrane metalloendopeptidase like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MMEL1 (membrane metalloendopeptidase like 1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mmel1 (membrane metallo-endopeptidase-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mmel1 (membrane metallo-endopeptidase-like 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nep4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	nep-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nep-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nep1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nep1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mmel1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	mmel1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Mmel1^{Tn(sb-T2/Bart3)2.255Mcwi}

Genetic Models:

F344-Mmel1^{Tn(sb-T2/Bart3)2.255Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	170,713,602 - 170,744,058 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	170,713,627 - 170,744,058 (+)	Ensembl				GRCr8
mRatBN7.2	5	165,431,278 - 165,461,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	165,431,343 - 165,461,716 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	168,136,416 - 168,166,854 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	169,957,822 - 169,988,264 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	169,920,362 - 169,950,802 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	172,273,450 - 172,303,905 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	172,273,459 - 172,304,225 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	175,729,143 - 175,759,868 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	171,675,007 - 171,703,353 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	163,639,889 - 163,668,234 (+)	NCBI		Celera
RGSC_v3.1	5	171,683,479 - 171,713,539 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

primary biliary cholangitis (ISO)

rheumatoid arthritis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

6-propyl-2-thiouracil (EXP)

allethrin (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

candoxatrilat (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclophosphamide (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

dimethylselenide (ISO)

fenvalerate (EXP)

furan (EXP)

hydroxyl (ISO)

mono(2-ethylhexyl) phthalate (ISO)

naphthalene (EXP)

omapatrilat (ISO)

propanal (ISO)

pyrethrins (EXP)

sodium arsenite (ISO)

Soman (EXP)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

protein processing (IBA)

proteolysis (IEA,ISO)

Cellular Component

endoplasmic reticulum (ISO)

extracellular region (IEA)

extracellular space (IDA,IEA,ISO)

Golgi apparatus (ISO)

membrane (IEA,ISO)

plasma membrane (IBA)

Molecular Function

endopeptidase activity (IEA,ISO)

hydrolase activity (IEA)

metal ion binding (IEA)

metalloendopeptidase activity (IBA,IDA,IEA)

metallopeptidase activity (IEA)

peptidase activity (IEA)

zinc ion binding (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin.	Rose C, etal., Biochem J. 2002 May 1;363(Pt 3):697-705.
7.	A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2.	Voisin S, etal., J Biol Chem. 2004 Oct 29;279(44):46172-81. Epub 2004 Aug 4.

Additional References at PubMed

PMID:10542292	PMID:10814502	PMID:12477932	PMID:12710972	PMID:15057822	PMID:16081046	PMID:18539150

Genomics

Comparative Map Data

Mmel1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	170,713,602 - 170,744,058 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	170,713,627 - 170,744,058 (+)	Ensembl				GRCr8
mRatBN7.2	5	165,431,278 - 165,461,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	165,431,343 - 165,461,716 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	168,136,416 - 168,166,854 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	169,957,822 - 169,988,264 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	169,920,362 - 169,950,802 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	172,273,450 - 172,303,905 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	172,273,459 - 172,304,225 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	175,729,143 - 175,759,868 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	171,675,007 - 171,703,353 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	163,639,889 - 163,668,234 (+)	NCBI		Celera
RGSC_v3.1	5	171,683,479 - 171,713,539 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

MMEL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	2,590,639 - 2,633,016 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	2,590,639 - 2,633,016 (-)	Ensembl			hg38	GRCh38
GRCh37	1	2,522,078 - 2,564,455 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	2,511,941 - 2,554,289 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	21,530 - 63,919 (+)	NCBI		Celera
Cytogenetic Map	1	p36.32	NCBI
HuRef	1	1,801,317 - 1,843,691 (-)	NCBI		HuRef
CHM1_1	1	2,509,160 - 2,551,374 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	2,032,284 - 2,074,662 (-)	NCBI		T2T-CHM13v2.0

Mmel1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	154,954,042 - 154,979,987 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	154,954,042 - 154,979,985 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	154,869,585 - 154,895,530 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	154,869,585 - 154,895,528 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	154,243,694 - 154,269,639 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	153,713,436 - 153,739,330 (+)	NCBI		MGSCv36	mm8
Celera	4	157,143,798 - 157,167,036 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	85.54	NCBI

Mmel1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	8,638,233 - 8,663,053 (+)	Ensembl
ChiLan1.0	NW_004955486	8,635,727 - 8,662,793 (+)	NCBI	ChiLan1.0	ChiLan1.0

MMEL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	225,614,185 - 225,656,859 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	224,274,769 - 224,317,395 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	1,323,914 - 1,362,178 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	2,462,621 - 2,504,213 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	2,462,621 - 2,504,213 (-)	Ensembl			panPan2	panpan1.1

MMEL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	57,434,880 - 57,467,973 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	57,434,886 - 57,465,911 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	57,448,632 - 57,481,167 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	57,638,951 - 57,671,485 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	57,638,957 - 57,669,464 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	57,630,277 - 57,662,801 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	57,522,566 - 57,555,107 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	57,912,337 - 57,944,882 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mmel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	28,468,571 - 28,499,453 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936737	970,504 - 997,067 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936737	970,504 - 997,452 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MMEL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	64,436,642 - 64,472,759 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	64,436,778 - 64,470,888 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,819,225 - 58,855,455 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MMEL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	128,916,051 - 128,963,545 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	128,921,369 - 128,963,188 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	33,291,779 - 33,306,944 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mmel1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	7,453,177 - 7,485,439 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	7,451,213 - 7,481,988 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mmel1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	5,819,744 - 5,847,326 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	672
Count of miRNA genes:	152
Interacting mature miRNAs:	172
Transcripts:	ENSRNOT00000017957, ENSRNOT00000064266, ENSRNOT00000064738
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	160111176	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat

Markers in Region

D5Got120

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	170,738,117 - 170,738,248 (+)	Marker Load Pipeline
mRatBN7.2	5	165,455,774 - 165,455,905 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	172,297,964 - 172,298,094	NCBI	Rnor6.0
Rnor_5.0	5	175,753,927 - 175,754,057	UniSTS	Rnor5.0
RGSC_v3.4	5	171,697,411 - 171,697,542	RGD	RGSC3.4
RGSC_v3.4	5	171,697,412 - 171,697,542	UniSTS	RGSC3.4
Celera	5	163,662,293 - 163,662,423	UniSTS
RGSC_v3.1	5	171,707,907 - 171,708,037	RGD
RH 3.4 Map	5	1153.6	RGD
RH 3.4 Map	5	1153.6	UniSTS
RH 2.0 Map	5	1144.4	RGD
Cytogenetic Map	5	q36	UniSTS

AU047969

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	165,431,956 - 165,432,116 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	172,274,149 - 172,274,308	NCBI	Rnor6.0
Rnor_5.0	5	175,729,802 - 175,729,961	UniSTS	Rnor5.0
RGSC_v3.4	5	171,673,597 - 171,673,756	UniSTS	RGSC3.4
Celera	5	163,638,479 - 163,638,638	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH138040

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	165,461,470 - 165,461,682 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	172,303,660 - 172,303,871	NCBI	Rnor6.0
Rnor_5.0	5	175,759,623 - 175,759,834	UniSTS	Rnor5.0
RGSC_v3.4	5	171,703,108 - 171,703,319	UniSTS	RGSC3.4
Celera	5	163,667,989 - 163,668,200	UniSTS
RH 3.4 Map	5	1153.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

Genetic Models

This gene Mmel1 is modified in the following models/strains:

F344-Mmel1^{Tn(sb-T2/Bart3)2.255Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	10	27	129	67	64	36	51	36	5	180	104	6	105	23	63	28	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC134160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017957 ⟹ ENSRNOP00000017957

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	170,713,629 - 170,744,058 (+)	Ensembl
mRatBN7.2 Ensembl	5	165,431,343 - 165,461,715 (+)	Ensembl
Rnor_6.0 Ensembl	5	172,273,459 - 172,304,225 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000064266 ⟹ ENSRNOP00000062904

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	170,715,689 - 170,744,050 (+)	Ensembl
mRatBN7.2 Ensembl	5	165,433,367 - 165,461,716 (+)	Ensembl
Rnor_6.0 Ensembl	5	172,275,734 - 172,303,596 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000151829 ⟹ ENSRNOP00000100706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	170,713,627 - 170,744,050 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000163920 ⟹ ENSRNOP00000101044

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	170,713,627 - 170,744,050 (+)	Ensembl

RefSeq Acc Id:

NM_001107997 ⟹ NP_001101467

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,629 - 170,744,058 (+)	NCBI
mRatBN7.2	5	165,431,283 - 165,461,715 (+)	NCBI
Rnor_6.0	5	172,275,559 - 172,303,905 (+)	NCBI
Rnor_5.0	5	175,729,143 - 175,759,868 (+)	NCBI
RGSC_v3.4	5	171,675,007 - 171,703,353 (+)	RGD
Celera	5	163,639,889 - 163,668,234 (+)	RGD

Sequence:

show sequence

CACGGGGTCCCCCGGGCACTCAGGGCACAGCTTAAAGCGTCGAGAGCGGAGACCAGGACAGAGC
ATTCCCCAAAGCACTAGCTTCAGTGTGCTCAAGGCATCCAAGCTCCAGCTGCCTCCCTCCTGGC
CCTGGCCCTGGGTGCTCAGCTGTGTGCCTTCCACCCAGAACCGGCTGATGGGGAAGTCGGAGAG
CTCAGTGGGGATGATGGAGAGAGCGGACAACTGTGGGAGGAGGCGCCTAGGCTTCGTGGAGTGT
GGGCTGCTGGTACTGCTGACACTGCTGTTGATGGGAGCCATAGTGACTCTGGGTGTCTTCTACA
GCATAGGGAAGCAGCTGCCCCTCTTAAATAGCCTGCTGCACGTCTCCCGGCATGAGAGGACGGT
TGTAAAACGAGCCGCCCTCAGAGATTCATCGCAGAAGAGTGACATCTGTACTACCCCAAGCTGC
GTGATAGCAGCTGCCAGAATCCTCCAGAACATGGACCAGTCAAAGAAACCCTGCGACAACTTCT
ATCAGTATGCTTGCGGAGGCTGGCTACGGCACCATGTGATCCCCGAGACCAACTCCAGATACAG
CGTCTTTGACATCCTTCGGGATGAGCTGGAGGTCATCCTCAAAGGGGTGCTGGAGGATTCCTCT
GTCCAGCACCGCCCAGCTGTGGAGAAGGCCAAGACACTGTACCGCTCCTGCATGAACCAGAGTG
TGATAGAGAAGAGAGACTCTGAGCCCCTGCTGAACGTCTTAGATATGATAGGAGGTTGGCCTGT
AGCCATGGACAAGTGGAATGAGACCATGGGCCCCAAGTGGGAACTGGAGCGGCAGTTGGCTGTG
TTGAACTCGCAGTTCAACAGGCGCGTCCTCATCGACCTCTTCATCTGGAATGATGACCAGAACT
CCAGCCGGCACGTCATCTACATAGACCAGCCCACCTTGGGCATGCCCTCCCGGGAGTACTATTT
CAAGGAAGACAGCCACCGGGTACGGGAAGCCTACCTGCAGTTCATGACATCAGTGGCCACTATG
CTGAGGAGAGACCTGAACCTGCCCGGGGAGACCGATTTGGTGCAGGAGGAAATGGCACAGGTGC
TGCATCTGGAGACACATCTGGCCAACGCCACGGTCCCCCAGGAGAAAAGGCATGATGTCACCGC
CCTGTATCACCGAATGGGCCTGGAGGAGCTGCAGGAAAGGTTTGGTCTGAAGGGGTTTAACTGG
ACTCTCTTCATACAAAACGTGCTGTCTTCTGTGCAAGTTGAGCTGCTCCCGAATGAGGAGGTGG
TGGTCTATGGCATCCCCTACCTGGAGAATCTTGAGGAGATCATTGACGTCTTCCCAGCACAGAC
CTTGCAAAACTACCTGGTGTGGCGCCTGGTGCTAGATCGCATCGGCAGCCTGAGCCAGAGATTC
AAAGAAGCGCGTGTGGACTACCGCAAGGCGCTGTACGGTACAACCATGGAGGAAGTACGCTGGC
GGGAGTGTGTCAGCTATGTCAACAGCAACATGGAGAGTGCCGTGGGCTCCCTCTACATCAAGCG
GGCCTTCTCCAAGGACAGCAAGAGCATAGTCAGTGAGCTTATCGAGAAGATACGGTCCGTGTTT
GTGGATAACCTGGACGAGTTGAACTGGATGGATGAGGAATCCAAGAAAAAGGCCCAGGAAAAGG
CCTTGAATATCCGGGAACAGATCGGCTACCCTGACTACATTTTGGAAGACAATAACAGACACCT
GGATGAGGAATACTCCAGTCTGACTTTCTCAGAGGACCTGTATTTTGAGAACGGGCTTCAGAAC
CTCAAGAACAATGCCCAAAGGAGCCTCAAGAAACTTCGGGAAAAGGTGGACCAGAATCTCTGGA
TCATTGGGGCTGCAGTGGTCAATGCATTCTACTCCCCAAACAGAAACCTGATCGTCTTTCCAGC
GGGGATCCTCCAGCCACCCTTCTTCAGCAAGGACCAACCACAGGCCTTGAATTTCGGGGGCATC
GGGATGGTGATTGGACACGAGATCACACACGGCTTTGATGATAACGGTCGGAACTTTGACAAGA
ATGGCAACATGCTGGACTGGTGGAGCAACTTCTCGGCCCGGCACTTCCGACAGCAGTCACAGTG
TATGATTTATCAGTACAGCAACTTCTCTTGGGAACTAGCAGACAACCAGAATGTGAACGGATTC
AGCACCCTCGGGGAGAACATCGCCGACAACGGCGGTGTGCGGCAGGCATACAAGGCTTACCTAC
AGTGGCTAGCTGAAGGCGGCAGAGACCAGAGACTGCCGGGACTGAACCTGACCTATGCTCAGCT
TTTCTTCATTAACTATGCCCAGGTGTGGTGTGGGTCCTACAGGCCGGAGTTCGCCATCCAGTCC
ATCAAGACAGATGTCCACAGTCCTCTTAAGTACAGGGTGCTGGGCTCACTACAGAACCTACCAG
GCTTCTCTGAGGCGTTCCACTGCCCACGAGGCAGCCCCATGCACCCTATGAATCGATGTCGCAT
CTGGTAGCCAAGGCTGAGCTATGCTGCGGCCCACGCCCCGCCACCCAGAGGCTTCGTGAATGGT
GTAGCCGGCATAGATGTGCAGGTTGTTGCCTGAAGGCCACTGGAGCCACCAGCCAGCCCTCCGC
GCCCAGCCTAGAGGGCAGCCACCCGCCCACATCTGGGATGAGTGGTGGTGCCTGGTCCTGCGCC
TTTTCCGGCCAGTGAGGGTCAGCGGCCCGGTAGGAGCAGTCAGCTGTCCCCCACCCTCTTCATA
GTGTGTGGCTAAATGTCCTCGAGCTTCAGACTTGAGCTAAGTAAACGCTTCAAAGAAGGC

hide sequence

RefSeq Acc Id:

XM_006239569 ⟹ XP_006239631

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,605 - 170,744,058 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,461,716 (+)	NCBI
Rnor_6.0	5	172,273,450 - 172,303,902 (+)	NCBI
Rnor_5.0	5	175,729,143 - 175,759,868 (+)	NCBI

Sequence:

show sequence

TCATCATAAAGGTGGGCCAGAAGCCAGCTCCATGTGACCTCACAGCCAGCTCGGCCTGACCGCT
GCTCTACTCCACCCAGAGCCTACCTTGGCCAGCTCACCCCAGCTCTGCGAGGTCCCAAACTAGC
CTATAGGACTTGCCAAGTGGCAGCTGACAGCACTAGAACCGGCTGATGGGGAAGTCGGAGAGCT
CAGTGGGGATGATGGAGAGAGCGGACAACTGTGGGAGGAGGCGCCTAGGCTTCGTGGAGTGTGG
GCTGCTGGTACTGCTGACACTGCTGTTGATGGGAGCCATAGTGACTCTGGGTGTCTTCTACAGC
ATAGGGAAGCAGCTGCCCCTCTTAAATAGCCTGCTGCACGTCTCCCGGCATGAGAGGACGGTTG
TAAAACGAGTCCTCAGAGATTCATCGCAGAAGAGTGACATCTGTACTACCCCAAGCTGCGTGAT
AGCAGCTGCCAGAATCCTCCAGAACATGGACCAGTCAAAGAAACCCTGCGACAACTTCTATCAG
TATGCTTGCGGAGGCTGGCTACGGCACCATGTGATCCCCGAGACCAACTCCAGATACAGCGTCT
TTGACATCCTTCGGGATGAGCTGGAGGTCATCCTCAAAGGGGTGCTGGAGGATTCCTCTGTCCA
GCACCGCCCAGCTGTGGAGAAGGCCAAGACACTGTACCGCTCCTGCATGAACCAGAGTGTGATA
GAGAAGAGAGACTCTGAGCCCCTGCTGAACGTCTTAGATATGATAGGAGGTTGGCCTGTAGCCA
TGGACAAGTGGAATGAGACCATGGGCCCCAAGTGGGAACTGGAGCGGCAGTTGGCTGTGTTGAA
CTCGCAGTTCAACAGGCGCGTCCTCATCGACCTCTTCATCTGGAATGATGACCAGAACTCCAGC
CGGCACGTCATCTACGTACGGGAAGCCTACCTGCAGTTCATGACATCAGTGGCCACTATGCTGA
GGAGAGACCTGAACCTGCCCGGGGAGACCGATTTGGTGCAGGAGGAAATGGCACAGGTGCTGCA
TCTGGAGACACATCTGGCCAACGCCACGGTCCCCCAGGAGAAAAGGCATGATGTCACCGCCCTG
TATCACCGAATGGGCCTGGAGGAGCTGCAGGAAAGGTTTGGTCTGAAGGGGTTTAACTGGACTC
TCTTCATACAAAACGTGCTGTCTTCTGTGCAAGTTGAGCTGCTCCCGAATGAGGAGGTGGTGGT
CTATGGCATCCCCTACCTGGAGAATCTTGAGGAGATCATTGACGTCTTCCCAGCACAGACCTTG
CAAAACTACCTGGTGTGGCGCCTGGTGCTAGATCGCATCGGCAGCCTGAGCCAGAGATTCAAAG
AAGCGCGTGTGGACTACCGCAAGGCGCTGTACGGTACAACCATGGAGGAAGTACGCTGGCGGGA
GTGTGTCAGCTATGTCAACAGCAACATGGAGAGTGCCGTGGGCTCCCTCTACATCAAGCGGGCC
TTCTCCAAGGACAGCAAGAGCATAGTCAGTGAGCTTATCGAGAAGATACGGTCCGTGTTTGTGG
ATAACCTGGACGAGTTGAACTGGATGGATGAGGAATCCAAGAAAAAGGCCCAGGAAAAGGCCTT
GAATATCCGGGAACAGATCGGCTACCCTGACTACATTTTGGAAGACAATAACAGACACCTGGAT
GAGGAATACTCCAGTCTGACTTTCTCAGAGGACCTGTATTTTGAGAACGGGCTTCAGAACCTCA
AGAACAATGCCCAAAGGAGCCTCAAGAAACTTCGGGAAAAGGTGGACCAGAATCTCTGGATCAT
TGGGGCTGCAGTGGTCAATGCATTCTACTCCCCAAACAGAAACCTGATCGTCTTTCCAGCGGGG
ATCCTCCAGCCACCCTTCTTCAGCAAGGACCAACCACAGGCCTTGAATTTCGGGGGCATCGGGA
TGGTGATTGGACACGAGATCACACACGGCTTTGATGATAACGGTCGGAACTTTGACAAGAATGG
CAACATGCTGGACTGGTGGAGCAACTTCTCGGCCCGGCACTTCCGACAGCAGTCACAGTGTATG
ATTTATCAGTACAGCAACTTCTCTTGGGAACTAGCAGACAACCAGAATGTGAACGGATTCAGCA
CCCTCGGGGAGAACATCGCCGACAACGGCGGTGTGCGGCAGGCATACAAGGCTTACCTACAGTG
GCTAGCTGAAGGCGGCAGAGACCAGAGACTGCCGGGACTGAACCTGACCTATGCTCAGCTTTTC
TTCATTAACTATGCCCAGGTGTGGTGTGGGTCCTACAGGCCGGAGTTCGCCATCCAGTCCATCA
AGACAGATGTCCACAGTCCTCTTAAGTACAGGGTGCTGGGCTCACTACAGAACCTACCAGGCTT
CTCTGAGGCGTTCCACTGCCCACGAGGCAGCCCCATGCACCCTATGAATCGATGTCGCATCTGG
TAGCCAAGGCTGAGCTATGCTGCGGCCCACGCCCCGCCACCCAGAGGCTTCGTGAATGGTGTAG
CCGGCATAGATGTGCAGGTTGTTGCCTGAAGGCCACTGGAGCCACCAGCCAGCCCTCCGCGCCC
AGCCTAGAGGGCAGCCACCCGCCCACATCTGGGATGAGTGGTGGTGCCTGGTCCTGCGCCTTTT
CCGGCCAGTGAGGGTCAGCGGCCCGGTAGGAGCAGTCAGCTGTCCCCCACCCTCTTCATAGTGT
GTGGCTAAATGTCCTCGAGCTTCAGACTTGAGCTAAGTAAACGCTTCAAAGAA

hide sequence

RefSeq Acc Id:

XM_006239570 ⟹ XP_006239632

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,605 - 170,744,058 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,461,710 (+)	NCBI
Rnor_6.0	5	172,273,450 - 172,303,904 (+)	NCBI
Rnor_5.0	5	175,729,143 - 175,759,868 (+)	NCBI

Sequence:

show sequence

TCATCATAAAGGTGGGCCAGAAGCCAGCTCCATGTGACCTCACAGCCAGCTCGGCCTGACCGCT
GCTCTACTCCACCCAGAGCCTACCTTGGCCAGCTCACCCCAGCTCTGCGAGGTCCCAAACTAGC
CTATAGGACTTGCCAAGTGGCAGCTGACAGCACTAGAACCGGCTGATGGGGAAGTCGGAGAGCT
CAGTGGGGATGATGGAGAGAGCGGACAACTGTGGGAGGAGGCGCCTAGGCTTCGTGGAGTGTGG
GCTGCTGGTACTGCTGACACTGCTGTTGATGGGAGCCATAGTGACTCTGGGTGTCTTCTACAGC
ATAGTCCTCAGAGATTCATCGCAGAAGAGTGACATCTGTACTACCCCAAGCTGCGTGATAGCAG
CTGCCAGAATCCTCCAGAACATGGACCAGTCAAAGAAACCCTGCGACAACTTCTATCAGTATGC
TTGCGGAGGCTGGCTACGGCACCATGTGATCCCCGAGACCAACTCCAGATACAGCGTCTTTGAC
ATCCTTCGGGATGAGCTGGAGGTCATCCTCAAAGGGGTGCTGGAGGATTCCTCTGTCCAGCACC
GCCCAGCTGTGGAGAAGGCCAAGACACTGTACCGCTCCTGCATGAACCAGAGTGTGATAGAGAA
GAGAGACTCTGAGCCCCTGCTGAACGTCTTAGATATGATAGGAGGTTGGCCTGTAGCCATGGAC
AAGTGGAATGAGACCATGGGCCCCAAGTGGGAACTGGAGCGGCAGTTGGCTGTGTTGAACTCGC
AGTTCAACAGGCGCGTCCTCATCGACCTCTTCATCTGGAATGATGACCAGAACTCCAGCCGGCA
CGTCATCTACATAGACCAGCCCACCTTGGGCATGCCCTCCCGGGAGTACTATTTCAAGGAAGAC
AGCCACCGGGTACGGGAAGCCTACCTGCAGTTCATGACATCAGTGGCCACTATGCTGAGGAGAG
ACCTGAACCTGCCCGGGGAGACCGATTTGGTGCAGGAGGAAATGGCACAGGTGCTGCATCTGGA
GACACATCTGGCCAACGCCACGGTCCCCCAGGAGAAAAGGCATGATGTCACCGCCCTGTATCAC
CGAATGGGCCTGGAGGAGCTGCAGGAAAGGTTTGGTCTGAAGGGGTTTAACTGGACTCTCTTCA
TACAAAACGTGCTGTCTTCTGTGCAAGTTGAGCTGCTCCCGAATGAGGAGGTGGTGGTCTATGG
CATCCCCTACCTGGAGAATCTTGAGGAGATCATTGACGTCTTCCCAGCACAGACCTTGCAAAAC
TACCTGGTGTGGCGCCTGGTGCTAGATCGCATCGGCAGCCTGAGCCAGAGATTCAAAGAAGCGC
GTGTGGACTACCGCAAGGCGCTGTACGGTACAACCATGGAGGAAGTACGCTGGCGGGAGTGTGT
CAGCTATGTCAACAGCAACATGGAGAGTGCCGTGGGCTCCCTCTACATCAAGCGGGCCTTCTCC
AAGGACAGCAAGAGCATAGTCAGTGAGCTTATCGAGAAGATACGGTCCGTGTTTGTGGATAACC
TGGACGAGTTGAACTGGATGGATGAGGAATCCAAGAAAAAGGCCCAGGAAAAGGCCTTGAATAT
CCGGGAACAGATCGGCTACCCTGACTACATTTTGGAAGACAATAACAGACACCTGGATGAGGAA
TACTCCAGTCTGACTTTCTCAGAGGACCTGTATTTTGAGAACGGGCTTCAGAACCTCAAGAACA
ATGCCCAAAGGAGCCTCAAGAAACTTCGGGAAAAGGTGGACCAGAATCTCTGGATCATTGGGGC
TGCAGTGGTCAATGCATTCTACTCCCCAAACAGAAACCTGATCGTCTTTCCAGCGGGGATCCTC
CAGCCACCCTTCTTCAGCAAGGACCAACCACAGGCCTTGAATTTCGGGGGCATCGGGATGGTGA
TTGGACACGAGATCACACACGGCTTTGATGATAACGGTCGGAACTTTGACAAGAATGGCAACAT
GCTGGACTGGTGGAGCAACTTCTCGGCCCGGCACTTCCGACAGCAGTCACAGTGTATGATTTAT
CAGTACAGCAACTTCTCTTGGGAACTAGCAGACAACCAGAATGTGAACGGATTCAGCACCCTCG
GGGAGAACATCGCCGACAACGGCGGTGTGCGGCAGGCATACAAGGCTTACCTACAGTGGCTAGC
TGAAGGCGGCAGAGACCAGAGACTGCCGGGACTGAACCTGACCTATGCTCAGCTTTTCTTCATT
AACTATGCCCAGGTGTGGTGTGGGTCCTACAGGCCGGAGTTCGCCATCCAGTCCATCAAGACAG
ATGTCCACAGTCCTCTTAAGTACAGGGTGCTGGGCTCACTACAGAACCTACCAGGCTTCTCTGA
GGCGTTCCACTGCCCACGAGGCAGCCCCATGCACCCTATGAATCGATGTCGCATCTGGTAGCCA
AGGCTGAGCTATGCTGCGGCCCACGCCCCGCCACCCAGAGGCTTCGTGAATGGTGTAGCCGGCA
TAGATGTGCAGGTTGTTGCCTGAAGGCCACTGGAGCCACCAGCCAGCCCTCCGCGCCCAGCCTA
GAGGGCAGCCACCCGCCCACATCTGGGATGAGTGGTGGTGCCTGGTCCTGCGCCTTTTCCGGCC
AGTGAGGGTCAGCGGCCCGGTAGGAGCAGTCAGCTGTCCCCCACCCTCTTCATAGTGTGTGGCT
AAATGTCCTCGAGCTTCAGACTTGAGCTAAGTAAACGCTTCAAAGAAGG

hide sequence

RefSeq Acc Id:

XM_008764360 ⟹ XP_008762582

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,605 - 170,744,058 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,461,710 (+)	NCBI
Rnor_6.0	5	172,290,395 - 172,303,904 (+)	NCBI

Sequence:

show sequence

GTAGCCTTTACCTTCCCTGCCAGGCAGCCCTGAGGAGTCCTCAGAGATTCATCGCAGAAGAGTG
ACATCTGTACTACCCCAAGCTGCGTGATAGCAGCTGCCAGAATCCTCCAGAACATGGACCAGTC
AAAGAAACCCTGCGACAACTTCTATCAGTATGCTTGCGGAGGCTGGCTACGGCACCATGTGATC
CCCGAGACCAACTCCAGATACAGCGTCTTTGACATCCTTCGGGATGAGCTGGAGGTCATCCTCA
AAGGGGTGCTGGAGGATTCCTCTGTCCAGCACCGCCCAGCTGTGGAGAAGGCCAAGACACTGTA
CCGCTCCTGCATGAACCAGAGTGTGATAGAGAAGAGAGACTCTGAGCCCCTGCTGAACGTCTTA
GATATGATAGGAGGTTGGCCTGTAGCCATGGACAAGTGGAATGAGACCATGGGCCCCAAGTGGG
AACTGGAGCGGCAGTTGGCTGTGTTGAACTCGCAGTTCAACAGGCGCGTCCTCATCGACCTCTT
CATCTGGAATGATGACCAGAACTCCAGCCGGCACGTCATCTACATAGACCAGCCCACCTTGGGC
ATGCCCTCCCGGGAGTACTATTTCAAGGAAGACAGCCACCGGGTACGGGAAGCCTACCTGCAGT
TCATGACATCAGTGGCCACTATGCTGAGGAGAGACCTGAACCTGCCCGGGGAGACCGATTTGGT
GCAGGAGGAAATGGCACAGGTGCTGCATCTGGAGACACATCTGGCCAACGCCACGGTCCCCCAG
GAGAAAAGGCATGATGTCACCGCCCTGTATCACCGAATGGGCCTGGAGGAGCTGCAGGAAAGGT
TTGGTCTGAAGGGGTTTAACTGGACTCTCTTCATACAAAACGTGCTGTCTTCTGTGCAAGTTGA
GCTGCTCCCGAATGAGGAGGTGGTGGTCTATGGCATCCCCTACCTGGAGAATCTTGAGGAGATC
ATTGACGTCTTCCCAGCACAGACCTTGCAAAACTACCTGGTGTGGCGCCTGGTGCTAGATCGCA
TCGGCAGCCTGAGCCAGAGATTCAAAGAAGCGCGTGTGGACTACCGCAAGGCGCTGTACGGTAC
AACCATGGAGGAAGTACGCTGGCGGGAGTGTGTCAGCTATGTCAACAGCAACATGGAGAGTGCC
GTGGGCTCCCTCTACATCAAGCGGGCCTTCTCCAAGGACAGCAAGAGCATAGTCAGTGAGCTTA
TCGAGAAGATACGGTCCGTGTTTGTGGATAACCTGGACGAGTTGAACTGGATGGATGAGGAATC
CAAGAAAAAGGCCCAGGAAAAGGCCTTGAATATCCGGGAACAGATCGGCTACCCTGACTACATT
TTGGAAGACAATAACAGACACCTGGATGAGGAATACTCCAGTCTGACTTTCTCAGAGGACCTGT
ATTTTGAGAACGGGCTTCAGAACCTCAAGAACAATGCCCAAAGGAGCCTCAAGAAACTTCGGGA
AAAGGTGGACCAGAATCTCTGGATCATTGGGGCTGCAGTGGTCAATGCATTCTACTCCCCAAAC
AGAAACCTGATCGTCTTTCCAGCGGGGATCCTCCAGCCACCCTTCTTCAGCAAGGACCAACCAC
AGGCCTTGAATTTCGGGGGCATCGGGATGGTGATTGGACACGAGATCACACACGGCTTTGATGA
TAACGGTCGGAACTTTGACAAGAATGGCAACATGCTGGACTGGTGGAGCAACTTCTCGGCCCGG
CACTTCCGACAGCAGTCACAGTGTATGATTTATCAGTACAGCAACTTCTCTTGGGAACTAGCAG
ACAACCAGAATGTGAACGGATTCAGCACCCTCGGGGAGAACATCGCCGACAACGGCGGTGTGCG
GCAGGCATACAAGGCTTACCTACAGTGGCTAGCTGAAGGCGGCAGAGACCAGAGACTGCCGGGA
CTGAACCTGACCTATGCTCAGCTTTTCTTCATTAACTATGCCCAGGTGTGGTGTGGGTCCTACA
GGCCGGAGTTCGCCATCCAGTCCATCAAGACAGATGTCCACAGTCCTCTTAAGTACAGGGTGCT
GGGCTCACTACAGAACCTACCAGGCTTCTCTGAGGCGTTCCACTGCCCACGAGGCAGCCCCATG
CACCCTATGAATCGATGTCGCATCTGGTAGCCAAGGCTGAGCTATGCTGCGGCCCACGCCCCGC
CACCCAGAGGCTTCGTGAATGGTGTAGCCGGCATAGATGTGCAGGTTGTTGCCTGAAGGCCACT
GGAGCCACCAGCCAGCCCTCCGCGCCCAGCCTAGAGGGCAGCCACCCGCCCACATCTGGGATGA
GTGGTGGTGCCTGGTCCTGCGCCTTTTCCGGCCAGTGAGGGTCAGCGGCCCGGTAGGAGCAGTC
AGCTGTCCCCCACCCTCTTCATAGTGTGTGGCTAAATGTCCTCGAGCTTCAGACTTGAGCTAAG
TAAACGCTTCAAAGAAGG

hide sequence

RefSeq Acc Id:

XM_039110112 ⟹ XP_038966040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,605 - 170,744,058 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,461,710 (+)	NCBI

RefSeq Acc Id:

XM_039110114 ⟹ XP_038966042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,604 - 170,741,027 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,458,684 (+)	NCBI

RefSeq Acc Id:

XM_039110115 ⟹ XP_038966043

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,604 - 170,741,030 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,458,672 (+)	NCBI

RefSeq Acc Id:

XM_039110116 ⟹ XP_038966044

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,602 - 170,739,393 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,457,041 (+)	NCBI

RefSeq Acc Id:

XM_039110117 ⟹ XP_038966045

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,713,603 - 170,739,392 (+)	NCBI
mRatBN7.2	5	165,431,278 - 165,457,041 (+)	NCBI

RefSeq Acc Id:

XM_063287836 ⟹ XP_063143906

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	170,734,162 - 170,744,058 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101467	(Get FASTA)	NCBI Sequence Viewer
	XP_006239631	(Get FASTA)	NCBI Sequence Viewer
	XP_006239632	(Get FASTA)	NCBI Sequence Viewer
	XP_008762582	(Get FASTA)	NCBI Sequence Viewer
	XP_038966040	(Get FASTA)	NCBI Sequence Viewer
	XP_038966042	(Get FASTA)	NCBI Sequence Viewer
	XP_038966043	(Get FASTA)	NCBI Sequence Viewer
	XP_038966044	(Get FASTA)	NCBI Sequence Viewer
	XP_038966045	(Get FASTA)	NCBI Sequence Viewer
	XP_063143906	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL81276	(Get FASTA)	NCBI Sequence Viewer
	EDL81277	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017957
	ENSRNOP00000062904
	ENSRNOP00000101044
GenBank Protein	P0C1T0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001101467 ⟸ NM_001107997

- UniProtKB:

A0A0H2UHK7 (UniProtKB/TrEMBL), A0A8L2QVP5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGKSESSVGMMERADNCGRRRLGFVECGLLVLLTLLLMGAIVTLGVFYSIGKQLPLLNSLLHVS
RHERTVVKRAALRDSSQKSDICTTPSCVIAAARILQNMDQSKKPCDNFYQYACGGWLRHHVIPE
TNSRYSVFDILRDELEVILKGVLEDSSVQHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDM
IGGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMP
SREYYFKEDSHRVREAYLQFMTSVATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEK
RHDVTALYHRMGLEELQERFGLKGFNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIID
VFPAQTLQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTMEEVRWRECVSYVNSNMESAVG
SLYIKRAFSKDSKSIVSELIEKIRSVFVDNLDELNWMDEESKKKAQEKALNIREQIGYPDYILE
DNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRN
LIVFPAGILQPPFFSKDQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHF
RQQSQCMIYQYSNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLQWLAEGGRDQRLPGLN
LTYAQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHP
MNRCRIW

hide sequence

RefSeq Acc Id:	XP_006239631 ⟸ XM_006239569
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QVP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKSESSVGMMERADNCGRRRLGFVECGLLVLLTLLLMGAIVTLGVFYSIGKQLPLLNSLLHVS RHERTVVKRVLRDSSQKSDICTTPSCVIAAARILQNMDQSKKPCDNFYQYACGGWLRHHVIPET NSRYSVFDILRDELEVILKGVLEDSSVQHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDMI GGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYVREAYLQFMT SVATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGL KGFNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGS LSQRFKEARVDYRKALYGTTMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSIVSELIEK IRSVFVDNLDELNWMDEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFE NGLQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRNLIVFPAGILQPPFFSKDQPQAL NFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQ NVNGFSTLGENIADNGGVRQAYKAYLQWLAEGGRDQRLPGLNLTYAQLFFINYAQVWCGSYRPE FAIQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW hide sequence

RefSeq Acc Id:	XP_006239632 ⟸ XM_006239570
- Peptide Label:	isoform X2
- UniProtKB:	A6IUM6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKSESSVGMMERADNCGRRRLGFVECGLLVLLTLLLMGAIVTLGVFYSIVLRDSSQKSDICTT PSCVIAAARILQNMDQSKKPCDNFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLE DSSVQHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDMIGGWPVAMDKWNETMGPKWELERQ LAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFKEDSHRVREAYLQFMTSV ATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGLKG FNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLS QRFKEARVDYRKALYGTTMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSIVSELIEKIR SVFVDNLDELNWMDEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENG LQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRNLIVFPAGILQPPFFSKDQPQALNF GGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQNV NGFSTLGENIADNGGVRQAYKAYLQWLAEGGRDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFA IQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW hide sequence

RefSeq Acc Id:	XP_008762582 ⟸ XM_008764360
- Peptide Label:	isoform X3
- UniProtKB:	A6IUM6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDQSKKPCDNFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSSVQHRPAVEKA KTLYRSCMNQSVIEKRDSEPLLNVLDMIGGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVL IDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFKEDSHRVREAYLQFMTSVATMLRRDLNLPGE TDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGLKGFNWTLFIQNVLSS VQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLSQRFKEARVDYRKA LYGTTMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSIVSELIEKIRSVFVDNLDELNWM DEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLK KLREKVDQNLWIIGAAVVNAFYSPNRNLIVFPAGILQPPFFSKDQPQALNFGGIGMVIGHEITH GFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQNVNGFSTLGENIADN GGVRQAYKAYLQWLAEGGRDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLK YRVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW hide sequence

Ensembl Acc Id:

ENSRNOP00000062904 ⟸ ENSRNOT00000064266

Ensembl Acc Id:

ENSRNOP00000017957 ⟸ ENSRNOT00000017957

RefSeq Acc Id:	XP_038966040 ⟸ XM_039110112
- Peptide Label:	isoform X3
- UniProtKB:	A6IUM6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038966042 ⟸ XM_039110114
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038966043 ⟸ XM_039110115
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038966044 ⟸ XM_039110116
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038966045 ⟸ XM_039110117
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063143906 ⟸ XM_063287836
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000100706 ⟸ ENSRNOT00000151829

Ensembl Acc Id:

ENSRNOP00000101044 ⟸ ENSRNOT00000163920

Protein Domains

Peptidase M13 Peptidase M13 C-terminal Peptidase M13 N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0C1T0-F1-model_v2	AlphaFold	P0C1T0	1-774	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694312

Promoter ID:

EPDNEW_R4837

Type:

initiation region

Name:

Mmel1_1

Description:

membrane metallo-endopeptidase-like 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	172,273,514 - 172,273,574	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309299	AgrOrtholog
BioCyc Gene	G2FUF-38946	BioCyc
Ensembl Genes	ENSRNOG00000012593	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000017957	ENTREZGENE
	ENSRNOT00000064266	ENTREZGENE
	ENSRNOT00000163920	ENTREZGENE
Gene3D-CATH	1.10.1380.10	UniProtKB/Swiss-Prot
	3.40.390.10	UniProtKB/Swiss-Prot
InterPro	MetalloPept_cat_dom_sf	UniProtKB/Swiss-Prot
	Peptidase_M13	UniProtKB/Swiss-Prot
	Peptidase_M13_C	UniProtKB/Swiss-Prot
	Peptidase_M13_dom_2	UniProtKB/Swiss-Prot
	Peptidase_M13_N	UniProtKB/Swiss-Prot
NCBI Gene	313755	ENTREZGENE
PANTHER	PTHR11733	UniProtKB/Swiss-Prot
	PTHR11733:SF141	UniProtKB/Swiss-Prot
Pfam	Peptidase_M13	UniProtKB/Swiss-Prot
	Peptidase_M13_N	UniProtKB/Swiss-Prot
PhenoGen	Mmel1	PhenoGen
PRINTS	NEPRILYSIN	UniProtKB/Swiss-Prot
PROSITE	NEPRILYSIN	UniProtKB/Swiss-Prot
	ZINC_PROTEASE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000012593	RatGTEx
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHK7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QVP5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0KZM8_RAT	UniProtKB/TrEMBL
	A0ABK0KZT9_RAT	UniProtKB/TrEMBL
	A6IUM5_RAT	UniProtKB/TrEMBL
	A6IUM6	ENTREZGENE, UniProtKB/TrEMBL
	MMEL1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Mmel1	membrane metallo-endopeptidase-like 1	Mell1_predicted	mel transforming oncogene-like 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Mell1_predicted	mel transforming oncogene-like 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD