Tmem26 (transmembrane protein 26) - Rat Genome Database

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Pathways
Gene: Tmem26 (transmembrane protein 26) Rattus norvegicus
Analyze
Symbol: Tmem26
Name: transmembrane protein 26
RGD ID: 1309273
Description: Predicted to be located in membrane. Orthologous to human TMEM26 (transmembrane protein 26); INTERACTS WITH acetamide; bisphenol A; bromobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC309724
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82019,819,780 - 19,872,978 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2019,821,991 - 19,871,041 (-)EnsemblGRCr8
mRatBN7.22019,820,768 - 19,872,561 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2019,822,975 - 19,872,023 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2020,551,919 - 20,600,969 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02019,904,377 - 19,953,425 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02020,379,620 - 20,428,657 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02021,640,655 - 21,689,655 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2021,642,484 - 21,689,553 (-)Ensemblrn6Rnor6.0
Rnor_5.02023,740,900 - 23,789,900 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42020,629,275 - 20,680,206 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2021,190,396 - 21,239,448 (-)NCBICelera
RGSC_v3.12020,644,950 - 20,693,757 (-)NCBI
Cytogenetic Map20p11NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tmem26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82019,819,780 - 19,872,978 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2019,821,991 - 19,871,041 (-)EnsemblGRCr8
mRatBN7.22019,820,768 - 19,872,561 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2019,822,975 - 19,872,023 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2020,551,919 - 20,600,969 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02019,904,377 - 19,953,425 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02020,379,620 - 20,428,657 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02021,640,655 - 21,689,655 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2021,642,484 - 21,689,553 (-)Ensemblrn6Rnor6.0
Rnor_5.02023,740,900 - 23,789,900 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42020,629,275 - 20,680,206 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2021,190,396 - 21,239,448 (-)NCBICelera
RGSC_v3.12020,644,950 - 20,693,757 (-)NCBI
Cytogenetic Map20p11NCBI
TMEM26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381061,406,642 - 61,453,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1061,406,642 - 61,453,381 (-)Ensemblhg38GRCh38
GRCh371063,166,400 - 63,213,139 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361062,836,414 - 62,883,214 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341062,836,413 - 62,883,214NCBI
Celera1056,433,398 - 56,480,207 (-)NCBICelera
Cytogenetic Map10q21.2NCBI
HuRef1057,155,405 - 57,202,187 (-)NCBIHuRef
CHM1_11063,448,585 - 63,495,392 (-)NCBICHM1_1
T2T-CHM13v2.01062,263,409 - 62,310,147 (-)NCBIT2T-CHM13v2.0
Tmem26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391068,559,576 - 68,618,485 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1068,559,476 - 68,618,480 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381068,723,746 - 68,782,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1068,723,646 - 68,782,650 (+)Ensemblmm10GRCm38
MGSCv371068,186,494 - 68,245,402 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361068,119,125 - 68,175,971 (+)NCBIMGSCv36mm8
Celera1069,821,833 - 69,878,470 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1035.64NCBI
Tmem26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542514,789,351 - 14,828,758 (-)Ensembl
ChiLan1.0NW_00495542514,787,440 - 14,828,596 (-)NCBIChiLan1.0ChiLan1.0
TMEM26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2873,621,621 - 73,667,142 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11073,626,755 - 73,672,347 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01057,943,726 - 57,990,163 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11060,274,519 - 60,320,369 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1060,274,208 - 60,320,369 (-)EnsemblpanPan2panpan1.1
TMEM26
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1413,461,953 - 13,508,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl413,464,262 - 13,509,232 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha413,666,146 - 13,714,125 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0413,723,403 - 13,771,511 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl413,723,429 - 13,772,479 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1413,712,739 - 13,760,665 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0413,828,001 - 13,875,960 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0414,193,121 - 14,241,168 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmem26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721367,573,001 - 67,617,989 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366141,659,426 - 1,703,182 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1464,877,935 - 64,925,505 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11464,881,216 - 64,925,449 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21469,957,059 - 70,001,294 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1969,824,830 - 69,871,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl969,842,831 - 69,868,283 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604830,711,890 - 30,760,239 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem26
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247912,258,289 - 2,297,599 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247912,256,585 - 2,297,603 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmem26
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11818,066,804 - 18,110,929 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tmem26
290 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:584
Count of miRNA genes:275
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000038095
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
BE104822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22019,824,403 - 19,824,616 (+)MAPPERmRatBN7.2
Rnor_6.02021,642,084 - 21,642,296NCBIRnor6.0
Rnor_5.02023,742,329 - 23,742,541UniSTSRnor5.0
RGSC_v3.42020,630,704 - 20,630,916UniSTSRGSC3.4
Celera2021,191,825 - 21,192,037UniSTS
Cytogenetic Map20p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 65 162 91 90 59 30 59 6 288 127 11 141 78 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000038095   ⟹   ENSRNOP00000038308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2019,821,991 - 19,871,041 (-)Ensembl
mRatBN7.2 Ensembl2019,822,975 - 19,872,023 (-)Ensembl
Rnor_6.0 Ensembl2021,642,484 - 21,689,553 (-)Ensembl
RefSeq Acc Id: NM_001107623   ⟹   NP_001101093
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82019,821,991 - 19,871,041 (-)NCBI
mRatBN7.22019,822,975 - 19,872,023 (-)NCBI
Rnor_6.02021,640,655 - 21,689,655 (-)NCBI
Rnor_5.02023,740,900 - 23,789,900 (-)NCBI
RGSC_v3.42020,629,275 - 20,680,206 (-)RGD
Celera2021,190,396 - 21,239,448 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098744   ⟹   XP_038954672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82019,819,780 - 19,854,470 (-)NCBI
mRatBN7.22019,820,768 - 19,855,451 (-)NCBI
RefSeq Acc Id: XR_005497258
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82019,824,256 - 19,872,978 (-)NCBI
mRatBN7.22019,825,208 - 19,872,561 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101093 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954672 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL97308 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038308
  ENSRNOP00000038308.2
RefSeq Acc Id: NP_001101093   ⟸   NM_001107623
- UniProtKB: D4ADJ8 (UniProtKB/TrEMBL),   A6JKU2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000038308   ⟸   ENSRNOT00000038095
RefSeq Acc Id: XP_038954672   ⟸   XM_039098744
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADJ8-F1-model_v2 AlphaFold D4ADJ8 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309273 AgrOrtholog
BioCyc Gene G2FUF-3927 BioCyc
Ensembl Genes ENSRNOG00000027859 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038095 ENTREZGENE
  ENSRNOT00000038095.5 UniProtKB/TrEMBL
InterPro Transmembrane_protein_26 UniProtKB/TrEMBL
KEGG Report rno:309724 UniProtKB/TrEMBL
NCBI Gene 309724 ENTREZGENE
PANTHER PTHR22168 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 26 UniProtKB/TrEMBL
Pfam Tmem26 UniProtKB/TrEMBL
PhenoGen Tmem26 PhenoGen
RatGTEx ENSRNOG00000027859 RatGTEx
UniProt A6JKU2 ENTREZGENE, UniProtKB/TrEMBL
  D4ADJ8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tmem26  transmembrane protein 26   Tmem26_predicted  transmembrane protein 26 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tmem26_predicted  transmembrane protein 26 (predicted)      Symbol and Name status set to approved 70820 APPROVED