Erp44 (endoplasmic reticulum protein 44) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Erp44 (endoplasmic reticulum protein 44) Rattus norvegicus
Analyze
Symbol: Erp44
Name: endoplasmic reticulum protein 44
RGD ID: 1309176
Description: Predicted to enable protein disulfide isomerase activity. Predicted to be involved in several processes, including protein folding; response to endoplasmic reticulum stress; and response to unfolded protein. Predicted to be located in cell surface and endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human ERP44 (endoplasmic reticulum protein 44); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BWK4; endoplasmic reticulum resident protein 44; LOC298066; thioredoxin domain containing 4 (endoplasmic reticulum); Txndc4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8567,313,245 - 67,406,207 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl567,312,098 - 67,406,444 (-)EnsemblGRCr8
mRatBN7.2562,516,550 - 62,610,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl562,516,551 - 62,610,761 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx564,492,222 - 64,585,236 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0566,311,515 - 66,404,538 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0566,280,980 - 66,374,000 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd567,447,068 - 67,540,018 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive569,019,316 - 69,112,270 (-)NCBILyon_Normotensive
Lyon_Hypertensive568,337,647 - 68,430,603 (-)NCBILyon_Hypertensive
F344_StmMcwi562,204,908 - 62,297,885 (-)NCBIF344_StmMcwi
Rnor_6.0563,937,866 - 64,030,827 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,937,784 - 64,030,901 (-)Ensemblrn6Rnor6.0
Rnor_5.0568,455,221 - 68,548,182 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4564,869,536 - 64,962,569 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera564,984,853 - 65,077,468 (+)NCBICelera
RGSC_v3.1564,874,574 - 64,967,608 (-)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
clofibrate  (ISO)
clozapine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
furfural  (ISO)
glafenine  (EXP)
ivermectin  (ISO)
L-serine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
morphine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosomorpholine  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (ISO)
permethrin  (EXP)
PhIP  (EXP)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11847130   PMID:15308636   PMID:19199708   PMID:19995400   PMID:22215678  


Genomics

Comparative Map Data
Erp44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8567,313,245 - 67,406,207 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl567,312,098 - 67,406,444 (-)EnsemblGRCr8
mRatBN7.2562,516,550 - 62,610,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl562,516,551 - 62,610,761 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx564,492,222 - 64,585,236 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0566,311,515 - 66,404,538 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0566,280,980 - 66,374,000 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd567,447,068 - 67,540,018 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive569,019,316 - 69,112,270 (-)NCBILyon_Normotensive
Lyon_Hypertensive568,337,647 - 68,430,603 (-)NCBILyon_Hypertensive
F344_StmMcwi562,204,908 - 62,297,885 (-)NCBIF344_StmMcwi
Rnor_6.0563,937,866 - 64,030,827 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,937,784 - 64,030,901 (-)Ensemblrn6Rnor6.0
Rnor_5.0568,455,221 - 68,548,182 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4564,869,536 - 64,962,569 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera564,984,853 - 65,077,468 (+)NCBICelera
RGSC_v3.1564,874,574 - 64,967,608 (-)NCBI
Cytogenetic Map5q22NCBI
ERP44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38999,979,185 - 100,099,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl999,979,185 - 100,099,052 (-)Ensemblhg38GRCh38
GRCh379102,741,467 - 102,861,282 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369101,781,282 - 101,901,151 (-)NCBIBuild 36Build 36hg18NCBI36
Celera973,254,858 - 73,374,731 (-)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef972,340,490 - 72,460,508 (-)NCBIHuRef
CHM1_19102,887,925 - 103,007,771 (-)NCBICHM1_1
T2T-CHM13v2.09112,150,810 - 112,270,620 (-)NCBIT2T-CHM13v2.0
Erp44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39448,190,711 - 48,279,635 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl448,193,323 - 48,279,558 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38448,190,711 - 48,279,635 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl448,193,323 - 48,279,558 (-)Ensemblmm10GRCm38
MGSCv37448,206,203 - 48,292,461 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36448,215,467 - 48,300,658 (-)NCBIMGSCv36mm8
Celera448,215,114 - 48,301,229 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.09NCBI
Erp44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541925,584,404 - 25,665,590 (+)Ensembl
ChiLan1.0NW_00495541925,584,404 - 25,665,590 (+)NCBIChiLan1.0ChiLan1.0
ERP44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21139,362,223 - 39,481,896 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1939,364,594 - 39,484,267 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0971,062,078 - 71,185,195 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1999,182,352 - 99,301,938 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl999,182,352 - 99,301,938 (-)EnsemblpanPan2panpan1.1
ERP44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11156,957,064 - 57,039,898 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1156,958,817 - 57,039,741 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1155,389,180 - 55,483,471 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01158,066,652 - 58,161,012 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1158,065,994 - 58,160,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11156,570,877 - 56,665,156 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01156,595,729 - 56,690,009 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01157,295,165 - 57,389,544 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Erp44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947171,839,892 - 171,923,197 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365248,383,891 - 8,470,855 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365248,387,234 - 8,470,776 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERP44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1241,785,146 - 241,897,539 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11241,788,801 - 241,897,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21270,077,943 - 270,216,303 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERP44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11239,333,924 - 39,448,994 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1239,333,944 - 39,448,535 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660353,103,895 - 3,218,823 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erp44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624825866,077 - 959,146 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624825865,901 - 962,661 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Erp44
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11101,286,771 - 101,375,247 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Erp44
636 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:592
Count of miRNA genes:292
Interacting mature miRNAs:368
Transcripts:ENSRNOT00000007711
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat

Markers in Region
D5Rat195  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8567,400,995 - 67,401,132 (+)Marker Load Pipeline
mRatBN7.2562,605,452 - 62,605,589 (+)MAPPERmRatBN7.2
Rnor_6.0564,025,844 - 64,025,980NCBIRnor6.0
Rnor_5.0568,543,199 - 68,543,335UniSTSRnor5.0
RGSC_v3.4564,957,359 - 64,957,495UniSTSRGSC3.4
RGSC_v3.4564,957,358 - 64,957,495RGDRGSC3.4
Celera564,989,911 - 64,990,043UniSTS
RGSC_v3.1564,962,398 - 64,962,534RGD
RH 3.4 Map5413.0RGD
RH 3.4 Map5413.0UniSTS
SHRSP x BN Map537.0299RGD
SHRSP x BN Map537.0299UniSTS
Cytogenetic Map5q22UniSTS
RH143564  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,549,044 - 62,550,358 (+)MAPPERmRatBN7.2
Rnor_6.0563,969,212 - 63,970,525NCBIRnor6.0
Rnor_5.0568,486,567 - 68,487,880UniSTSRnor5.0
RGSC_v3.4564,901,067 - 64,902,380UniSTSRGSC3.4
Celera565,045,135 - 65,046,448UniSTS
RH 3.4 Map5413.0UniSTS
Cytogenetic Map5q22UniSTS
RH127879  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,517,357 - 62,517,563 (+)MAPPERmRatBN7.2
Rnor_6.0563,937,526 - 63,937,731NCBIRnor6.0
Rnor_5.0568,454,881 - 68,455,086UniSTSRnor5.0
RGSC_v3.4564,869,196 - 64,869,401UniSTSRGSC3.4
Celera565,077,603 - 65,077,808UniSTS
RH 3.4 Map5402.1UniSTS
Cytogenetic Map5q22UniSTS
RH129120  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,517,756 - 62,517,914 (+)MAPPERmRatBN7.2
Rnor_6.0563,937,925 - 63,938,082NCBIRnor6.0
Rnor_5.0568,455,280 - 68,455,437UniSTSRnor5.0
RGSC_v3.4564,869,595 - 64,869,752UniSTSRGSC3.4
Celera565,077,252 - 65,077,409UniSTS
RH 3.4 Map5413.6UniSTS
Cytogenetic Map5q22UniSTS
RH132223  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,516,688 - 62,516,908 (+)MAPPERmRatBN7.2
Rnor_6.0563,936,857 - 63,937,076NCBIRnor6.0
Rnor_5.0568,454,212 - 68,454,431UniSTSRnor5.0
RGSC_v3.4564,868,527 - 64,868,746UniSTSRGSC3.4
Celera565,078,258 - 65,078,477UniSTS
RH 3.4 Map5413.8UniSTS
Cytogenetic Map5q22UniSTS
BE098131  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,516,805 - 62,516,961 (+)MAPPERmRatBN7.2
Rnor_6.0563,936,974 - 63,937,129NCBIRnor6.0
Rnor_5.0568,454,329 - 68,454,484UniSTSRnor5.0
RGSC_v3.4564,868,644 - 64,868,799UniSTSRGSC3.4
Celera565,078,205 - 65,078,360UniSTS
RH 3.4 Map5414.2UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007711   ⟹   ENSRNOP00000007711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl567,312,098 - 67,406,304 (-)Ensembl
mRatBN7.2 Ensembl562,516,551 - 62,610,761 (-)Ensembl
Rnor_6.0 Ensembl563,937,784 - 64,030,901 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139765   ⟹   ENSRNOP00000102730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl567,312,098 - 67,406,295 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150331   ⟹   ENSRNOP00000102997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl567,312,098 - 67,406,444 (-)Ensembl
RefSeq Acc Id: NM_001008317   ⟹   NP_001008318
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,313,245 - 67,406,207 (-)NCBI
mRatBN7.2562,517,698 - 62,610,664 (-)NCBI
Dahl_SR_JrHsd567,447,068 - 67,540,018 (-)NCBI
Lyon_Normotensive569,019,316 - 69,112,270 (-)NCBI
Lyon_Hypertensive568,337,647 - 68,430,603 (-)NCBI
F344_StmMcwi562,204,908 - 62,297,885 (-)NCBI
Rnor_6.0563,937,866 - 64,030,827 (-)NCBI
Rnor_5.0568,455,221 - 68,548,182 (-)NCBI
RGSC_v3.4564,869,536 - 64,962,569 (-)RGD
Celera564,984,853 - 65,077,468 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001008318 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO17785 (Get FASTA)   NCBI Sequence Viewer  
  EDL78194 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007711
  ENSRNOP00000007711.3
  ENSRNOP00000102730.1
  ENSRNOP00000102997.1
RefSeq Acc Id: NP_001008318   ⟸   NM_001008317
- Peptide Label: precursor
- UniProtKB: Q5VLR5 (UniProtKB/TrEMBL),   A6KJF6 (UniProtKB/TrEMBL),   F7FLN3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007711   ⟸   ENSRNOT00000007711
Ensembl Acc Id: ENSRNOP00000102997   ⟸   ENSRNOT00000150331
Ensembl Acc Id: ENSRNOP00000102730   ⟸   ENSRNOT00000139765
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5VLR5-F1-model_v2 AlphaFold Q5VLR5 1-406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693724
Promoter ID:EPDNEW_R4248
Type:initiation region
Name:Erp44_1
Description:endoplasmic reticulum protein 44
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0564,030,885 - 64,030,945EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309176 AgrOrtholog
BioCyc Gene G2FUF-41359 BioCyc
Ensembl Genes ENSRNOG00000005841 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007711 ENTREZGENE
  ENSRNOT00000007711.7 UniProtKB/TrEMBL
  ENSRNOT00000139765.1 UniProtKB/TrEMBL
  ENSRNOT00000150331.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro ERP44 UniProtKB/TrEMBL
  ERp44_PDI_b UniProtKB/TrEMBL
  ERp44_PDI_b' UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
KEGG Report rno:298066 UniProtKB/TrEMBL
NCBI Gene 298066 ENTREZGENE
PANTHER ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 UniProtKB/TrEMBL
  ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/TrEMBL
  Thioredoxin_6 UniProtKB/TrEMBL
PhenoGen Erp44 PhenoGen
PROSITE THIOREDOXIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005841 RatGTEx
Superfamily-SCOP Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A0ABK0L2G2_RAT UniProtKB/TrEMBL
  A0ABK0LH05_RAT UniProtKB/TrEMBL
  A6KJF6 ENTREZGENE, UniProtKB/TrEMBL
  F7FLN3 ENTREZGENE, UniProtKB/TrEMBL
  Q5VLR5 ENTREZGENE
UniProt Secondary Q5VLR5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Erp44  endoplasmic reticulum protein 44  Txndc4  thioredoxin domain containing 4 (endoplasmic reticulum)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Txndc4  thioredoxin domain containing 4 (endoplasmic reticulum)  Txndc4_predicted  thioredoxin domain containing 4 (endoplasmic reticulum) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Txndc4_predicted  thioredoxin domain containing 4 (endoplasmic reticulum) (predicted)      Symbol and Name status set to approved 70820 APPROVED