Opa3 (outer mitochondrial membrane lipid metabolism regulator OPA3) - Rat Genome Database

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Gene: Opa3 (outer mitochondrial membrane lipid metabolism regulator OPA3) Rattus norvegicus
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Symbol: Opa3
Name: outer mitochondrial membrane lipid metabolism regulator OPA3
RGD ID: 1309147
Description: Predicted to be involved in visual perception. Predicted to act upstream of or within several processes, including bone development; fat cell differentiation; and neuromuscular process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Orthologous to human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC308409; NEWGENE_1309147; OPA3, outer mitochondrial membrane lipid metabolism regulator; optic atrophy 3; optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); optic atrophy 3 (human); optic atrophy 3 protein; optic atrophy 3 protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Opa3-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,007,707 - 88,037,639 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,025,696 - 88,028,657 (+)EnsemblGRCr8
GRCr8 Ensembl188,009,435 - 88,041,698 (+)EnsemblGRCr8
mRatBN7.2178,879,612 - 78,910,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,880,114 - 78,901,469 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl178,880,862 - 78,913,056 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,270,502 - 84,289,703 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,828,026 - 92,847,264 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,025,584 - 86,044,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,141,630 - 80,160,145 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,141,630 - 80,160,145 (+)Ensemblrn6Rnor6.0
Rnor_5.0181,408,113 - 81,426,628 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,592,874 - 78,611,029 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,343,904 - 73,362,059 (+)NCBICelera
RGSC_v3.1178,670,662 - 78,687,666 (+)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:15342707   PMID:18222992   PMID:18614015   PMID:21613372   PMID:22869679  


Genomics

Comparative Map Data
Opa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,007,707 - 88,037,639 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,025,696 - 88,028,657 (+)EnsemblGRCr8
GRCr8 Ensembl188,009,435 - 88,041,698 (+)EnsemblGRCr8
mRatBN7.2178,879,612 - 78,910,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,880,114 - 78,901,469 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl178,880,862 - 78,913,056 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,270,502 - 84,289,703 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,828,026 - 92,847,264 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,025,584 - 86,044,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,141,630 - 80,160,145 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,141,630 - 80,160,145 (+)Ensemblrn6Rnor6.0
Rnor_5.0181,408,113 - 81,426,628 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,592,874 - 78,611,029 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,343,904 - 73,362,059 (+)NCBICelera
RGSC_v3.1178,670,662 - 78,687,666 (+)NCBI
Cytogenetic Map1q21NCBI
OPA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,527,427 - 45,584,802 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,527,767 - 45,602,212 (-)Ensemblhg38GRCh38
GRCh371946,030,685 - 46,088,060 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,722,865 - 50,779,962 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341950,747,641 - 50,779,917NCBI
Celera1942,837,136 - 42,894,236 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,460,247 - 42,517,324 (-)NCBIHuRef
CHM1_11946,034,268 - 46,091,400 (-)NCBICHM1_1
T2T-CHM13v2.01948,354,701 - 48,412,074 (-)NCBIT2T-CHM13v2.0
Opa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,962,314 - 18,980,742 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,962,259 - 18,990,468 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38719,228,389 - 19,246,817 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,228,334 - 19,256,543 (+)Ensemblmm10GRCm38
MGSCv37719,813,738 - 19,832,166 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36718,386,905 - 18,405,158 (+)NCBIMGSCv36mm8
Celera716,641,243 - 16,659,819 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.48NCBI
Opa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557460,652 - 82,343 (-)Ensembl
ChiLan1.0NW_00495557460,652 - 82,343 (-)NCBIChiLan1.0ChiLan1.0
OPA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,689,574 - 51,750,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,560,990 - 53,622,129 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,477,467 - 42,546,814 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,073,322 - 51,130,555 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,073,322 - 51,130,555 (-)EnsemblpanPan2panpan1.1
Opa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,598,813 - 17,647,957 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,964,237 - 1,995,175 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,961,571 - 1,996,637 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,917,379 - 51,964,488 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1651,917,956 - 51,967,624 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OPA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,974,455 - 39,032,780 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,001,467 - 39,032,347 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607318,595,898 - 18,655,810 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Opa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,580,823 - 7,605,443 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248327,580,402 - 7,619,122 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Opa3
338 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:170
Interacting mature miRNAs:207
Transcripts:ENSRNOT00000029552
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
D4Mit141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,898,725 - 78,898,843 (+)MAPPERmRatBN7.2
Rnor_6.0180,159,322 - 80,159,439NCBIRnor6.0
Rnor_5.0181,425,805 - 81,425,922UniSTSRnor5.0
RGSC_v3.4178,610,206 - 78,610,323UniSTSRGSC3.4
Celera173,361,236 - 73,361,353UniSTS
Cytogenetic Map1q21UniSTS
BE102432  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,890,314 - 78,890,464 (+)MAPPERmRatBN7.2
Rnor_6.0180,150,553 - 80,150,702NCBIRnor6.0
Rnor_5.0181,417,036 - 81,417,185UniSTSRnor5.0
RGSC_v3.4178,601,797 - 78,601,946UniSTSRGSC3.4
Celera173,352,827 - 73,352,976UniSTS
RH 3.4 Map1768.6UniSTS
Cytogenetic Map1q21UniSTS
RH134672  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,900,206 - 78,900,413 (+)MAPPERmRatBN7.2
Rnor_6.0180,160,803 - 80,161,009NCBIRnor6.0
Rnor_5.0181,427,286 - 81,427,492UniSTSRnor5.0
RGSC_v3.4178,611,687 - 78,611,893UniSTSRGSC3.4
Celera173,362,717 - 73,362,923UniSTS
RH 3.4 Map1768.5UniSTS
Cytogenetic Map1q21UniSTS
RH135203  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8188,027,340 - 88,027,530 (+)Marker Load Pipeline
mRatBN7.2178,899,322 - 78,899,511 (+)MAPPERmRatBN7.2
Rnor_6.0180,159,919 - 80,160,107NCBIRnor6.0
Rnor_5.0181,426,402 - 81,426,590UniSTSRnor5.0
RGSC_v3.4178,610,803 - 78,610,991UniSTSRGSC3.4
Celera173,361,833 - 73,362,021UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000029552   ⟹   ENSRNOP00000030360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,025,696 - 88,028,657 (+)Ensembl
mRatBN7.2 Ensembl178,880,114 - 78,901,469 (+)Ensembl
Rnor_6.0 Ensembl180,141,630 - 80,160,145 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096607   ⟹   ENSRNOP00000095404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,009,435 - 88,041,698 (+)Ensembl
mRatBN7.2 Ensembl178,880,862 - 78,913,056 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099247   ⟹   ENSRNOP00000097116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,009,435 - 88,038,178 (+)Ensembl
mRatBN7.2 Ensembl178,881,437 - 78,910,175 (+)Ensembl
RefSeq Acc Id: NM_001399653   ⟹   NP_001386582
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,009,412 - 88,028,659 (+)NCBI
mRatBN7.2178,881,392 - 78,900,641 (+)NCBI
RefSeq Acc Id: XM_017589999   ⟹   XP_017445488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,007,707 - 88,037,639 (+)NCBI
mRatBN7.2178,879,612 - 78,910,453 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386582 (Get FASTA)   NCBI Sequence Viewer  
  XP_017445488 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68945 (Get FASTA)   NCBI Sequence Viewer  
  EDM08221 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030360.5
  ENSRNOP00000095404.1
  ENSRNOP00000097116
  ENSRNOP00000097116.1
Ensembl Acc Id: ENSRNOP00000030360   ⟸   ENSRNOT00000029552
RefSeq Acc Id: XP_017445488   ⟸   XM_017589999
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AQX4 (UniProtKB/TrEMBL),   A0A8I6AQB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001386582   ⟸   NM_001399653
Ensembl Acc Id: ENSRNOP00000097116   ⟸   ENSRNOT00000099247
Ensembl Acc Id: ENSRNOP00000095404   ⟸   ENSRNOT00000096607

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF67-F1-model_v2 AlphaFold B5DF67 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689764
Promoter ID:EPDNEW_R289
Type:multiple initiation site
Name:Opa3_1
Description:OPA3, outer mitochondrial membrane lipid metabolism regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,141,653 - 80,141,713EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309147 AgrOrtholog
BioCyc Gene G2FUF-60520 BioCyc
Ensembl Genes ENSRNOG00000025890 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000064373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029552.8 UniProtKB/TrEMBL
  ENSRNOT00000096607.2 UniProtKB/TrEMBL
  ENSRNOT00000099247 ENTREZGENE
  ENSRNOT00000099247.2 UniProtKB/TrEMBL
InterPro OPA3-like UniProtKB/TrEMBL
NCBI Gene 308409 ENTREZGENE
PANTHER OPTIC ATROPHY 3 PROTEIN UniProtKB/TrEMBL
  PTHR12499 UniProtKB/TrEMBL
Pfam OPA3 UniProtKB/TrEMBL
PhenoGen Opa3 PhenoGen
RatGTEx ENSRNOG00000025890 RatGTEx
  ENSRNOG00000064373 RatGTEx
UniProt A0A8I6AQB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A9K3Y7T5_RAT UniProtKB/TrEMBL
  B5DF67_RAT UniProtKB/TrEMBL
UniProt Secondary D4A4M6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Opa3  outer mitochondrial membrane lipid metabolism regulator OPA3  NEWGENE_1309147  optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)  Data merged from RGD:149736447 737654 PROVISIONAL
2021-08-09 NEWGENE_1309147  optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)      Symbol and Name status set to provisional 45752 PROVISIONAL
2020-08-13 Opa3  outer mitochondrial membrane lipid metabolism regulator OPA3  Opa3  OPA3, outer mitochondrial membrane lipid metabolism regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-09-06 Opa3  OPA3, outer mitochondrial membrane lipid metabolism regulator  Opa3  optic atrophy 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-22 Opa3  optic atrophy 3  Opa3  optic atrophy 3 (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-27 Opa3  optic atrophy 3 (human)  Opa3  optic atrophy 3   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Opa3  optic atrophy 3   Opa3_predicted  optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Opa3_predicted  optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (predicted)      Symbol and Name status set to approved 70820 APPROVED