Ttll1 (TTL family tubulin polyglutamylase complex subunit L1) - Rat Genome Database

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Gene: Ttll1 (TTL family tubulin polyglutamylase complex subunit L1) Rattus norvegicus
Analyze
Symbol: Ttll1
Name: TTL family tubulin polyglutamylase complex subunit L1
RGD ID: 1309124
Description: Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including cerebellar Purkinje cell differentiation; cilium organization; and mucociliary clearance. Predicted to be located in several cellular components, including cytoskeleton; extracellular region; and motile cilium. Predicted to be active in ciliary basal body and microtubule. Orthologous to human TTLL1 (TTL family tubulin polyglutamylase complex subunit L1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362969; PGs3; polyglutamylase complex subunit TTLL1; probable tubulin polyglutamylase TTLL1; tubulin polyglutamylase complex subunit 3; tubulin polyglutamylase TTLL1; tubulin tyrosine ligase like 1; tubulin tyrosine ligase-like 1; tubulin tyrosine ligase-like family, member 1; tubulin--tyrosine ligase-like protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,499,536 - 116,528,833 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7116,499,535 - 116,528,833 (-)EnsemblGRCr8
mRatBN7.27114,619,509 - 114,648,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7116,374,253 - 116,403,529 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,599,670 - 118,629,049 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,569,144 - 118,598,511 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,338,396 - 124,367,719 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)Ensemblrn6Rnor6.0
Rnor_5.07124,327,308 - 124,356,639 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47121,420,125 - 121,441,444 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7110,932,407 - 110,961,694 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15890843   PMID:17499049   PMID:19182904   PMID:20442420   PMID:20498047   PMID:29440671   PMID:29593216   PMID:30420556  


Genomics

Comparative Map Data
Ttll1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,499,536 - 116,528,833 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7116,499,535 - 116,528,833 (-)EnsemblGRCr8
mRatBN7.27114,619,509 - 114,648,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7116,374,253 - 116,403,529 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,599,670 - 118,629,049 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,569,144 - 118,598,511 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,338,396 - 124,367,719 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)Ensemblrn6Rnor6.0
Rnor_5.07124,327,308 - 124,356,639 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47121,420,125 - 121,441,444 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7110,932,407 - 110,961,694 (-)NCBICelera
Cytogenetic Map7q34NCBI
TTLL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,039,516 - 43,089,391 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,039,516 - 43,089,427 (-)Ensemblhg38GRCh38
GRCh372243,435,522 - 43,485,397 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,765,589 - 41,815,373 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342241,760,142 - 41,809,927NCBI
Celera2227,346,102 - 27,395,837 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2226,394,153 - 26,443,736 (-)NCBIHuRef
CHM1_12243,395,326 - 43,445,000 (-)NCBICHM1_1
T2T-CHM13v2.02243,520,523 - 43,570,587 (-)NCBIT2T-CHM13v2.0
Ttll1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,367,258 - 83,402,675 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,367,970 - 83,395,094 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381583,483,057 - 83,518,474 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,483,769 - 83,510,893 (-)Ensemblmm10GRCm38
MGSCv371583,314,199 - 83,341,337 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361583,311,538 - 83,338,643 (-)NCBIMGSCv36mm8
Celera1585,617,197 - 85,644,203 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
Ttll1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541328,234,486 - 28,250,688 (-)Ensembl
ChiLan1.0NW_00495541328,234,964 - 28,250,899 (-)NCBIChiLan1.0ChiLan1.0
TTLL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22352,864,209 - 52,912,749 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12255,556,957 - 55,605,725 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02223,924,628 - 23,973,282 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,128,224 - 42,174,850 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,128,224 - 42,174,850 (-)EnsemblpanPan2panpan1.1
TTLL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11022,456,150 - 22,492,375 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1022,456,146 - 22,488,505 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1022,392,648 - 22,439,139 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01023,200,588 - 23,247,276 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1023,200,588 - 23,247,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11022,919,827 - 22,966,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01023,239,254 - 23,285,573 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01023,413,992 - 23,460,493 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ttll1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049456,091,553 - 6,110,264 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936718869,876 - 884,684 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936718869,901 - 884,708 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTLL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl55,793,780 - 5,827,633 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.155,793,760 - 5,827,622 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.253,216,125 - 3,250,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTLL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11925,576,525 - 25,616,413 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1925,576,379 - 25,616,328 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604599,827,235 - 99,869,254 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttll1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247525,883,042 - 5,903,687 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247525,883,039 - 5,901,333 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ttll1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11252,895,877 - 252,921,023 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ttll1
118 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:104
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000055978
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
AV014541  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27114,619,815 - 114,619,909 (+)MAPPERmRatBN7.2
Rnor_6.07124,338,703 - 124,338,796NCBIRnor6.0
Rnor_5.07124,327,615 - 124,327,708UniSTSRnor5.0
Celera7110,932,713 - 110,932,806UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 91 59 6 355 191 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC087669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000055978   ⟹   ENSRNOP00000052832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7116,499,537 - 116,528,833 (-)Ensembl
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)Ensembl
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110361   ⟹   ENSRNOP00000081132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7116,499,535 - 116,526,373 (-)Ensembl
mRatBN7.2 Ensembl7114,619,765 - 114,648,751 (-)Ensembl
RefSeq Acc Id: NM_001012200   ⟹   NP_001012200
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,537 - 116,528,833 (-)NCBI
mRatBN7.27114,619,510 - 114,648,806 (-)NCBI
Rnor_6.07124,338,397 - 124,367,630 (-)NCBI
Rnor_5.07124,327,308 - 124,356,639 (-)NCBI
RGSC_v3.47121,420,125 - 121,441,444 (+)RGD
Celera7110,932,407 - 110,961,694 (-)RGD
Sequence:
RefSeq Acc Id: NM_001393857   ⟹   NP_001380786
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,537 - 116,528,833 (-)NCBI
mRatBN7.27114,619,510 - 114,648,806 (-)NCBI
RefSeq Acc Id: XM_006242104   ⟹   XP_006242166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
mRatBN7.27114,619,509 - 114,648,850 (-)NCBI
Rnor_6.07124,338,396 - 124,367,719 (-)NCBI
Rnor_5.07124,327,308 - 124,356,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079601   ⟹   XP_038935529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,824 (-)NCBI
mRatBN7.27114,619,509 - 114,648,850 (-)NCBI
RefSeq Acc Id: XM_063263932   ⟹   XP_063120002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,824 (-)NCBI
RefSeq Acc Id: XM_063263933   ⟹   XP_063120003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,826 (-)NCBI
RefSeq Acc Id: XM_063263934   ⟹   XP_063120004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
RefSeq Acc Id: XM_063263935   ⟹   XP_063120005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
RefSeq Acc Id: XM_063263937   ⟹   XP_063120007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,523,800 (-)NCBI
RefSeq Acc Id: XR_010053011
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,910 - 116,528,826 (-)NCBI
RefSeq Acc Id: XR_010053012
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,910 - 116,528,831 (-)NCBI
RefSeq Acc Id: NP_001012200   ⟸   NM_001012200
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242166   ⟸   XM_006242104
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052832   ⟸   ENSRNOT00000055978
RefSeq Acc Id: XP_038935529   ⟸   XM_039079601
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000081132   ⟸   ENSRNOT00000110361
RefSeq Acc Id: NP_001380786   ⟸   NM_001393857
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120003   ⟸   XM_063263933
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063120002   ⟸   XM_063263932
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120005   ⟸   XM_063263935
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120004   ⟸   XM_063263934
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120007   ⟸   XM_063263937
- Peptide Label: isoform X4
Protein Domains
TTL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPI9-F1-model_v2 AlphaFold Q5PPI9 1-423 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695548
Promoter ID:EPDNEW_R6073
Type:initiation region
Name:Ttll1_1
Description:tubulin tyrosine ligase like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07124,367,645 - 124,367,705EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309124 AgrOrtholog
BioCyc Gene G2FUF-32601 BioCyc
Ensembl Genes ENSRNOG00000010141 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055978 ENTREZGENE
  ENSRNOT00000055978.5 UniProtKB/Swiss-Prot
  ENSRNOT00000110361 ENTREZGENE
Gene3D-CATH ATP-grasp fold, B domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7316813 IMAGE-MGC_LOAD
InterPro TTL/TTLL_fam UniProtKB/Swiss-Prot
KEGG Report rno:362969 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105511 IMAGE-MGC_LOAD
NCBI Gene 362969 ENTREZGENE
PANTHER PTHR12241:SF31 UniProtKB/Swiss-Prot
  TUBULIN POLYGLUTAMYLASE UniProtKB/Swiss-Prot
Pfam TTL UniProtKB/Swiss-Prot
PhenoGen Ttll1 PhenoGen
PROSITE TTL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010141 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot
UniProt A0A8I6G7K0 ENTREZGENE, UniProtKB/TrEMBL
  Q5PPI9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-12-16 Ttll1  TTL family tubulin polyglutamylase complex subunit L1  Ttll1  tubulin tyrosine ligase like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-25 Ttll1  tubulin tyrosine ligase like 1  Ttll1  tubulin tyrosine ligase-like family, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ttll1  tubulin tyrosine ligase-like family, member 1  Ttll1  tubulin tyrosine ligase-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ttll1  tubulin tyrosine ligase-like 1  Ttll1_predicted  tubulin tyrosine ligase-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ttll1_predicted  tubulin tyrosine ligase-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED