Sec23a (Sec23 homolog A, COPII coat complex component) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Sec23a (Sec23 homolog A, COPII coat complex component) Rattus norvegicus
Analyze
Symbol: Sec23a
Name: Sec23 homolog A, COPII coat complex component
RGD ID: 1309103
Description: Predicted to enable GTPase activator activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading and protein localization to plasma membrane. Predicted to be located in bounding membrane of organelle; cytosol; and perinuclear region of cytoplasm. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in craniolenticulosutural dysplasia. Orthologous to human SEC23A (SEC23 homolog A, COPII coat complex component); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: protein transport protein Sec23A; SEC23 homolog A; Sec23 homolog A (S. cerevisiae); Sec23 homolog A, coat complex II component; SEC23A (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8682,393,699 - 82,442,594 (-)NCBIGRCr8
mRatBN7.2676,658,793 - 76,706,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl676,658,427 - 76,706,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx677,111,637 - 77,158,214 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0677,410,966 - 77,457,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0676,838,431 - 76,885,014 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0680,059,742 - 80,107,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl680,060,916 - 80,107,236 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0689,585,614 - 89,633,225 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4679,660,575 - 79,706,898 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1679,661,840 - 79,704,989 (-)NCBI
Celera675,420,329 - 75,466,292 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
ciglitazone  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
inulin  (ISO)
ivermectin  (ISO)
LY294002  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
microcystin-LR  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
trichloroethene  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8898360   PMID:11042173   PMID:12477932   PMID:15642376   PMID:17499046   PMID:18843296   PMID:21187406   PMID:27354378   PMID:28259758   PMID:28442536   PMID:28801610  


Genomics

Comparative Map Data
Sec23a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8682,393,699 - 82,442,594 (-)NCBIGRCr8
mRatBN7.2676,658,793 - 76,706,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl676,658,427 - 76,706,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx677,111,637 - 77,158,214 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0677,410,966 - 77,457,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0676,838,431 - 76,885,014 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0680,059,742 - 80,107,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl680,060,916 - 80,107,236 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0689,585,614 - 89,633,225 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4679,660,575 - 79,706,898 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1679,661,840 - 79,704,989 (-)NCBI
Celera675,420,329 - 75,466,292 (-)NCBICelera
Cytogenetic Map6q23NCBI
SEC23A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381439,031,919 - 39,103,235 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1439,031,919 - 39,109,646 (-)EnsemblGRCh38hg38GRCh38
GRCh371439,501,123 - 39,572,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361438,570,874 - 38,642,188 (-)NCBINCBI36Build 36hg18NCBI36
Build 341438,570,873 - 38,642,188NCBI
Celera1419,365,589 - 19,437,057 (-)NCBICelera
Cytogenetic Map14q21.1NCBI
HuRef1419,615,598 - 19,686,718 (-)NCBIHuRef
CHM1_11439,499,753 - 39,571,039 (-)NCBICHM1_1
T2T-CHM13v2.01433,220,592 - 33,291,912 (-)NCBIT2T-CHM13v2.0
Sec23a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391259,005,170 - 59,058,803 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1259,005,169 - 59,058,803 (-)EnsemblGRCm39 Ensembl
GRCm381258,958,384 - 59,012,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1258,958,383 - 59,012,017 (-)EnsemblGRCm38mm10GRCm38
MGSCv371260,059,371 - 60,113,004 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361259,876,396 - 59,930,029 (-)NCBIMGSCv36mm8
Celera1260,121,595 - 60,175,287 (-)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1225.97NCBI
Sec23a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540922,189,181 - 22,247,467 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540922,192,549 - 22,243,090 (+)NCBIChiLan1.0ChiLan1.0
SEC23A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21540,365,649 - 40,438,197 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11439,582,163 - 39,652,931 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01419,802,612 - 19,873,076 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11438,159,381 - 38,229,366 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1438,159,381 - 38,229,550 (-)Ensemblpanpan1.1panPan2
SEC23A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1817,205,960 - 17,292,067 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl817,234,394 - 17,292,638 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha817,017,543 - 17,103,065 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0817,328,852 - 17,414,117 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl817,356,719 - 17,414,078 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1817,016,525 - 17,101,723 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0817,087,718 - 17,173,549 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0817,374,646 - 17,460,016 (-)NCBIUU_Cfam_GSD_1.0
Sec23a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864049,137,896 - 49,198,555 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649412,642,870 - 12,699,218 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649412,643,790 - 12,702,390 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC23A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl761,113,802 - 61,193,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1761,113,760 - 61,184,218 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2765,656,352 - 65,725,762 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEC23A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12415,801,945 - 15,874,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2415,801,509 - 15,874,994 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660534,845,443 - 4,918,617 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec23a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248138,499,721 - 8,558,110 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248138,502,473 - 8,558,078 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec23a
297 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:67
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000006369
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)67222764181132889Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat

Markers in Region
RH128536  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2676,658,923 - 76,659,122 (+)MAPPERmRatBN7.2
Rnor_6.0680,059,874 - 80,060,072NCBIRnor6.0
Rnor_5.0689,585,746 - 89,585,944UniSTSRnor5.0
RGSC_v3.4679,659,536 - 79,659,734UniSTSRGSC3.4
Celera675,419,290 - 75,419,488UniSTS
RH 3.4 Map6546.8UniSTS
Cytogenetic Map6q23UniSTS
RH139244  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2676,698,520 - 76,698,644 (+)MAPPERmRatBN7.2
Rnor_6.0680,099,747 - 80,099,870NCBIRnor6.0
Rnor_5.0689,625,619 - 89,625,742UniSTSRnor5.0
RGSC_v3.4679,699,409 - 79,699,532UniSTSRGSC3.4
Celera675,458,829 - 75,458,952UniSTS
RH 3.4 Map6547.2UniSTS
Cytogenetic Map6q23UniSTS
RH140991  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2676,689,135 - 76,689,346 (+)MAPPERmRatBN7.2
Rnor_6.0680,090,363 - 80,090,573NCBIRnor6.0
Rnor_5.0689,616,235 - 89,616,445UniSTSRnor5.0
RGSC_v3.4679,690,025 - 79,690,235UniSTSRGSC3.4
Celera675,449,502 - 75,449,712UniSTS
RH 3.4 Map6547.29UniSTS
Cytogenetic Map6q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 41 57 41 18 41 8 11 74 31 41 11 8
Low 1 2 1 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006369   ⟹   ENSRNOP00000006369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl676,658,427 - 76,706,035 (-)Ensembl
Rnor_6.0 Ensembl680,060,916 - 80,107,236 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084611   ⟹   ENSRNOP00000071102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl676,658,427 - 76,706,035 (-)Ensembl
Rnor_6.0 Ensembl680,062,703 - 80,102,635 (-)Ensembl
RefSeq Acc Id: NM_001105732   ⟹   NP_001099202
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,394,860 - 82,440,904 (-)NCBI
mRatBN7.2676,659,963 - 76,706,008 (-)NCBI
Rnor_6.0680,060,913 - 80,107,236 (-)NCBI
Rnor_5.0689,585,614 - 89,633,225 (-)NCBI
RGSC_v3.4679,660,575 - 79,706,898 (-)RGD
Celera675,420,329 - 75,466,292 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764661   ⟹   XP_008762883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,393,699 - 82,441,061 (-)NCBI
mRatBN7.2676,658,793 - 76,706,124 (-)NCBI
Rnor_6.0680,059,742 - 80,107,340 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112796   ⟹   XP_038968724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,393,699 - 82,441,098 (-)NCBI
mRatBN7.2676,658,793 - 76,706,125 (-)NCBI
RefSeq Acc Id: XM_039112797   ⟹   XP_038968725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,393,699 - 82,433,839 (-)NCBI
mRatBN7.2676,658,793 - 76,699,017 (-)NCBI
RefSeq Acc Id: XM_063262377   ⟹   XP_063118447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,393,699 - 82,441,027 (-)NCBI
RefSeq Acc Id: XM_063262378   ⟹   XP_063118448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8682,393,699 - 82,442,594 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001099202   ⟸   NM_001105732
- UniProtKB: B5DFC3 (UniProtKB/TrEMBL),   F7F6X6 (UniProtKB/TrEMBL),   A0A0G2JZM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762883   ⟸   XM_008764661
- Peptide Label: isoform X1
- UniProtKB: B5DFC3 (UniProtKB/TrEMBL),   F7F6X6 (UniProtKB/TrEMBL),   A0A0G2JZM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006369   ⟸   ENSRNOT00000006369
RefSeq Acc Id: ENSRNOP00000071102   ⟸   ENSRNOT00000084611
RefSeq Acc Id: XP_038968724   ⟸   XM_039112796
- Peptide Label: isoform X1
- UniProtKB: B5DFC3 (UniProtKB/TrEMBL),   F7F6X6 (UniProtKB/TrEMBL),   A0A0G2JZM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968725   ⟸   XM_039112797
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118448   ⟸   XM_063262378
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118447   ⟸   XM_063262377
- Peptide Label: isoform X1
Protein Domains
Gelsolin-like   Sec23/Sec24 beta-sandwich   Sec23/Sec24 helical   Sec23/Sec24 trunk   Zinc finger Sec23/Sec24-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DFC3-F1-model_v2 AlphaFold B5DFC3 1-765 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694613
Promoter ID:EPDNEW_R5138
Type:initiation region
Name:Sec23a_1
Description:Sec23 homolog A, coat complex II component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0680,107,211 - 80,107,271EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309103 AgrOrtholog
BioCyc Gene G2FUF-37389 BioCyc
Ensembl Genes ENSRNOG00000004657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006369.7 UniProtKB/TrEMBL
  ENSRNOT00000084611.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
  beta-sandwich domain of Sec23/24 UniProtKB/TrEMBL
  Sec23/Sec24 helical domain UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom UniProtKB/TrEMBL
  Gelsolin-like_dom_sf UniProtKB/TrEMBL
  Gelsolin_dom UniProtKB/TrEMBL
  Sec23 UniProtKB/TrEMBL
  Sec23/24_helical_dom UniProtKB/TrEMBL
  Sec23/24_helical_dom_sf UniProtKB/TrEMBL
  Sec23/24_trunk_dom UniProtKB/TrEMBL
  Sec23_24_beta_S UniProtKB/TrEMBL
  Sec23_C UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
  Znf_Sec23_Sec24 UniProtKB/TrEMBL
  Znf_Sec23_Sec24_sf UniProtKB/TrEMBL
KEGG Report rno:58817 UniProtKB/TrEMBL
NCBI Gene 58817 ENTREZGENE
PANTHER PROTEIN TRANSPORT PROTEIN SEC23A UniProtKB/TrEMBL
  PTHR11141 UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/TrEMBL
  Sec23_BS UniProtKB/TrEMBL
  Sec23_helical UniProtKB/TrEMBL
  Sec23_trunk UniProtKB/TrEMBL
  zf-Sec23_Sec24 UniProtKB/TrEMBL
PhenoGen Sec23a PhenoGen
RatGTEx ENSRNOG00000004657 RatGTEx
Superfamily-SCOP beta-sandwich domain of Sec23/24 UniProtKB/TrEMBL
  Sec23_helical UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
  SSF82754 UniProtKB/TrEMBL
  Znf_Sec23_Sec24 UniProtKB/TrEMBL
UniProt A0A0G2JZM2 ENTREZGENE, UniProtKB/TrEMBL
  B5DFC3 ENTREZGENE, UniProtKB/TrEMBL
  F7F6X6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-11 Sec23a  Sec23 homolog A, COPII coat complex component  Sec23a  Sec23 homolog A, coat complex II component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Sec23a  Sec23 homolog A, coat complex II component  Sec23a  Sec23 homolog A, COPII coat complex component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-13 Sec23a  Sec23 homolog A, COPII coat complex component  Sec23a  Sec23 homolog A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Sec23a  Sec23 homolog A (S. cerevisiae)  Sec23a  SEC23A (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sec23a  SEC23A (S. cerevisiae)   Sec23a_predicted  SEC23A (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sec23a_predicted  SEC23A (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED