Ppp4r3a (protein phosphatase 4, regulatory subunit 3A) - Rat Genome Database

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Gene: Ppp4r3a (protein phosphatase 4, regulatory subunit 3A) Rattus norvegicus
Analyze
Symbol: Ppp4r3a
Name: protein phosphatase 4, regulatory subunit 3A
RGD ID: 1309059
Description: Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage response and regulation of double-strand break repair. Predicted to act upstream of or within positive regulation of gluconeogenesis and protein dephosphorylation. Predicted to be located in cytosol and nuclear speck. Predicted to be part of protein phosphatase 4 complex. Predicted to be active in nucleoplasm. Orthologous to human PPP4R3A (protein phosphatase 4 regulatory subunit 3A); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314388; RGD1309059; serine/threonine-protein phosphatase 4 regulatory subunit 3A; similar to KIAA2010 protein; SMEK homolog 1, suppressor of mek1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); Smek1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,032,068 - 126,098,329 (-)NCBIGRCr8
mRatBN7.26120,302,508 - 120,365,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,302,511 - 120,365,891 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6120,457,500 - 120,499,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06120,754,202 - 120,796,180 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,089,044 - 120,131,024 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,040,803 - 125,083,496 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,040,803 - 125,060,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06134,260,318 - 134,303,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46125,329,321 - 125,354,083 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16125,315,498 - 125,358,904 (-)NCBI
Celera6117,830,409 - 117,872,995 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleoplasm  (IBA,ISO)
nucleus  (ISO)
protein phosphatase 4 complex  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:15326124   PMID:20876121  


Genomics

Comparative Map Data
Ppp4r3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,032,068 - 126,098,329 (-)NCBIGRCr8
mRatBN7.26120,302,508 - 120,365,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,302,511 - 120,365,891 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6120,457,500 - 120,499,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06120,754,202 - 120,796,180 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,089,044 - 120,131,024 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,040,803 - 125,083,496 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,040,803 - 125,060,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06134,260,318 - 134,303,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46125,329,321 - 125,354,083 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16125,315,498 - 125,358,904 (-)NCBI
Celera6117,830,409 - 117,872,995 (-)NCBICelera
Cytogenetic Map6q32NCBI
PPP4R3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381491,457,508 - 91,510,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1491,457,508 - 91,510,554 (-)EnsemblGRCh38hg38GRCh38
GRCh371491,923,852 - 91,976,898 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,993,708 - 91,046,397 (-)NCBINCBI36Build 36hg18NCBI36
Celera1471,972,721 - 72,025,463 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,100,431 - 72,153,269 (-)NCBIHuRef
CHM1_11491,862,107 - 91,914,785 (-)NCBICHM1_1
T2T-CHM13v2.01485,682,749 - 85,735,802 (-)NCBIT2T-CHM13v2.0
Ppp4r3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912101,005,668 - 101,051,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12101,005,668 - 101,049,961 (-)EnsemblGRCm39 Ensembl
GRCm3812101,039,409 - 101,083,737 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12101,039,409 - 101,083,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712102,277,619 - 102,321,912 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612101,440,568 - 101,484,450 (-)NCBIMGSCv36mm8
Celera12102,266,439 - 102,310,731 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.17NCBI
Ppp4r3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543813,729,949 - 13,769,189 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543813,731,900 - 13,769,189 (-)NCBIChiLan1.0ChiLan1.0
PPP4R3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,607,630 - 92,663,099 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11491,823,988 - 91,879,617 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,083,948 - 72,137,158 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,429,512 - 91,481,006 (-)NCBIpanpan1.1PanPan1.1panPan2
PPP4R3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1862,304,805 - 62,344,232 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl862,305,947 - 62,344,147 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha861,882,231 - 61,921,384 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0862,575,974 - 62,615,348 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl862,576,504 - 62,615,274 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1862,255,227 - 62,294,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0862,306,118 - 62,345,243 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0862,635,753 - 62,675,109 (-)NCBIUU_Cfam_GSD_1.0
Ppp4r3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,601,609 - 13,645,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648818,422,741 - 18,467,430 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648818,423,353 - 18,467,363 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP4R3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,111,332 - 113,148,954 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17113,111,305 - 113,148,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27119,663,267 - 119,700,061 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP4R3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12469,219,313 - 69,270,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2469,218,583 - 69,270,929 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605356,469,945 - 56,521,712 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp4r3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473411,160,356 - 11,197,817 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473411,160,253 - 11,197,264 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp4r3a
213 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:78
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000034961
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
D6Hmgc2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21176,238,067 - 76,238,098 (+)MAPPERmRatBN7.2
mRatBN7.26130,324,474 - 130,324,552 (-)MAPPERmRatBN7.2
mRatBN7.26120,328,758 - 120,328,931 (+)MAPPERmRatBN7.2
Rnor_6.06125,067,157 - 125,067,331NCBIRnor6.0
Rnor_5.06134,286,672 - 134,286,846UniSTSRnor5.0
Celera6117,856,779 - 117,856,965UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BF407152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA506701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA513249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO400159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV215275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY321166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV776435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ087395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034961   ⟹   ENSRNOP00000038439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6120,302,511 - 120,322,087 (-)Ensembl
Rnor_6.0 Ensembl6125,040,803 - 125,060,482 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106200   ⟹   ENSRNOP00000095747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6120,302,511 - 120,344,593 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110961   ⟹   ENSRNOP00000097346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6120,302,511 - 120,344,593 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114004   ⟹   ENSRNOP00000091226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6120,302,511 - 120,365,891 (-)Ensembl
RefSeq Acc Id: NM_001108050   ⟹   NP_001101520
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,074,150 (-)NCBI
mRatBN7.26120,302,511 - 120,344,593 (-)NCBI
Rnor_6.06125,040,803 - 125,083,238 (-)NCBI
Rnor_5.06134,260,318 - 134,303,011 (-)NCBI
RGSC_v3.46125,329,321 - 125,354,083 (-)RGD
Celera6117,830,409 - 117,872,737 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271174   ⟹   NP_001258103
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,074,150 (-)NCBI
mRatBN7.26120,302,511 - 120,344,593 (-)NCBI
Rnor_6.06125,040,899 - 125,083,496 (-)NCBI
Rnor_5.06134,260,318 - 134,303,011 (-)NCBI
Celera6117,830,505 - 117,872,995 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112354   ⟹   XP_038968282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,098,329 (-)NCBI
mRatBN7.26120,302,508 - 120,365,907 (-)NCBI
RefSeq Acc Id: XM_039112355   ⟹   XP_038968283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,098,329 (-)NCBI
mRatBN7.26120,302,508 - 120,365,850 (-)NCBI
RefSeq Acc Id: XM_039112356   ⟹   XP_038968284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,085,879 (-)NCBI
mRatBN7.26120,302,508 - 120,356,324 (-)NCBI
RefSeq Acc Id: XM_039112357   ⟹   XP_038968285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,038,477 - 126,084,183 (-)NCBI
mRatBN7.26120,308,921 - 120,344,721 (-)NCBI
RefSeq Acc Id: XM_063261975   ⟹   XP_063118045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,032,068 - 126,098,329 (-)NCBI
RefSeq Acc Id: NP_001101520   ⟸   NM_001108050
- Peptide Label: isoform 2
- UniProtKB: A6JEI6 (UniProtKB/TrEMBL),   A0A8I6ARL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258103   ⟸   NM_001271174
- Peptide Label: isoform 1
- UniProtKB: A0A8I6AS21 (UniProtKB/TrEMBL),   A0A8I6ARL9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000038439   ⟸   ENSRNOT00000034961
RefSeq Acc Id: XP_038968282   ⟸   XM_039112354
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GJF4 (UniProtKB/TrEMBL),   D4ABC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968283   ⟸   XM_039112355
- Peptide Label: isoform X3
- UniProtKB: D4ABC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968284   ⟸   XM_039112356
- Peptide Label: isoform X3
- UniProtKB: D4ABC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968285   ⟸   XM_039112357
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000091226   ⟸   ENSRNOT00000114004
Ensembl Acc Id: ENSRNOP00000097346   ⟸   ENSRNOT00000110961
Ensembl Acc Id: ENSRNOP00000095747   ⟸   ENSRNOT00000106200
RefSeq Acc Id: XP_063118045   ⟸   XM_063261975
- Peptide Label: isoform X2
Protein Domains
Serine/threonine-protein phosphatase 4 regulatory

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ABC4-F1-model_v2 AlphaFold D4ABC4 1-721 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309059 AgrOrtholog
BioCyc Gene G2FUF-36478 BioCyc
Ensembl Genes ENSRNOG00000027773 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034961.7 UniProtKB/TrEMBL
  ENSRNOT00000106200.1 UniProtKB/TrEMBL
  ENSRNOT00000110961.1 UniProtKB/TrEMBL
  ENSRNOT00000114004.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF625 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PP4_regulatory_subunit_3 UniProtKB/TrEMBL
KEGG Report rno:314388 UniProtKB/TrEMBL
NCBI Gene 314388 ENTREZGENE
PANTHER ATP SYNTHASE GAMMA-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A UniProtKB/TrEMBL
Pfam EVH1_PP4R3 UniProtKB/TrEMBL
  SMK-1 UniProtKB/TrEMBL
PhenoGen Ppp4r3a PhenoGen
RatGTEx ENSRNOG00000027773 RatGTEx
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A8I6ARL9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AS21 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJF4 ENTREZGENE, UniProtKB/TrEMBL
  A6JEI6 ENTREZGENE, UniProtKB/TrEMBL
  D4ABC4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-01 Ppp4r3a  protein phosphatase 4, regulatory subunit 3A  Smek1  SMEK homolog 1, suppressor of mek1 (Dictyostelium)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Smek1  SMEK homolog 1, suppressor of mek1 (Dictyostelium)  RGD1309059_predicted  similar to KIAA2010 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1309059_predicted  similar to KIAA2010 protein (predicted)  LOC314388_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314388_predicted  similar to KIAA2010 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL