Dmrt2 (doublesex and mab-3 related transcription factor 2) - Rat Genome Database

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Pathways
Gene: Dmrt2 (doublesex and mab-3 related transcription factor 2) Rattus norvegicus
Analyze
Symbol: Dmrt2
Name: doublesex and mab-3 related transcription factor 2
RGD ID: 1309047
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within embryonic skeletal system development; positive regulation of myotome development; and regulation of somitogenesis. Predicted to be active in nucleus. Orthologous to human DMRT2 (doublesex and mab-3 related transcription factor 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: doublesex- and mab-3-related transcription factor 2; LOC309430
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,743,935 - 232,750,431 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1232,743,942 - 232,750,431 (+)EnsemblGRCr8
mRatBN7.21223,317,543 - 223,324,131 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1223,317,642 - 223,324,131 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1231,765,233 - 231,771,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01238,695,310 - 238,701,799 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01231,516,080 - 231,522,569 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01243,662,819 - 243,669,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,662,823 - 243,669,312 (+)Ensemblrn6Rnor6.0
Rnor_5.01250,921,208 - 250,927,697 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41229,114,066 - 229,120,555 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1220,519,356 - 220,525,845 (+)NCBICelera
RGSC_v3.11229,277,771 - 229,284,321 (+)NCBI
Cytogenetic Map1q51NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16387292   PMID:17605809   PMID:17974128   PMID:21203428  


Genomics

Comparative Map Data
Dmrt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,743,935 - 232,750,431 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1232,743,942 - 232,750,431 (+)EnsemblGRCr8
mRatBN7.21223,317,543 - 223,324,131 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1223,317,642 - 223,324,131 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1231,765,233 - 231,771,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01238,695,310 - 238,701,799 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01231,516,080 - 231,522,569 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01243,662,819 - 243,669,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,662,823 - 243,669,312 (+)Ensemblrn6Rnor6.0
Rnor_5.01250,921,208 - 250,927,697 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41229,114,066 - 229,120,555 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1220,519,356 - 220,525,845 (+)NCBICelera
RGSC_v3.11229,277,771 - 229,284,321 (+)NCBI
Cytogenetic Map1q51NCBI
DMRT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3891,050,357 - 1,057,552 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl91,049,000 - 1,057,563 (+)Ensemblhg38GRCh38
GRCh3791,050,357 - 1,057,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3691,040,601 - 1,047,552 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3491,041,613 - 1,047,550NCBI
Celera9968,351 - 975,559 (+)NCBICelera
Cytogenetic Map9p24.3NCBI
HuRef91,003,690 - 1,010,898 (+)NCBIHuRef
CHM1_191,050,543 - 1,057,751 (+)NCBICHM1_1
T2T-CHM13v2.091,004,786 - 1,059,221 (+)NCBIT2T-CHM13v2.0
Dmrt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391925,649,758 - 25,656,355 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1925,649,775 - 25,656,355 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381925,672,394 - 25,679,013 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1925,672,411 - 25,678,991 (+)Ensemblmm10GRCm38
MGSCv371925,746,901 - 25,753,481 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361925,739,508 - 25,746,088 (+)NCBIMGSCv36mm8
Celera1926,467,110 - 26,473,669 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1920.53NCBI
Dmrt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554345,528,625 - 5,535,783 (+)NCBIChiLan1.0ChiLan1.0
DMRT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211123,525,583 - 123,531,379 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19123,531,526 - 123,537,322 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09860,271 - 867,704 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.191,054,211 - 1,061,228 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl91,055,473 - 1,060,962 (+)EnsemblpanPan2panpan1.1
DMRT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1189,873,380 - 89,880,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl189,875,670 - 89,880,641 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha190,341,426 - 90,348,439 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0190,422,291 - 90,429,308 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl190,423,483 - 90,433,354 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1190,070,195 - 90,077,186 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0189,780,950 - 89,787,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0190,549,936 - 90,556,943 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dmrt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947137,308,844 - 137,315,836 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365033,857,165 - 3,864,147 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365033,857,165 - 3,864,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DMRT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,745,502 - 220,757,324 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11220,745,493 - 220,799,779 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,943,593 - 246,952,893 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DMRT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11278,461,974 - 78,472,868 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1278,461,987 - 78,468,684 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ChlSab1.1 Ensembl1278,461,987 - 78,468,684 (-)NCBIChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603866,841,726 - 66,842,950 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dmrt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247365,722,404 - 5,730,633 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247365,721,984 - 5,730,558 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dmrt2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1225,780,898 - 25,787,417 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dmrt2
43 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:70
Interacting mature miRNAs:72
Transcripts:ENSRNOT00000067372
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367243666627Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
5508828Leukc3Leukocyte quantity QTL 3eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1227535119233480676Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
8693661Alc34Alcohol consumption QTL 342.20.611drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1221820316234540296Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1223964326236074012Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
8693618Alc25Alcohol consumption QTL 2530.28drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 12 27 75 50 51 20 14 20 6 191 74 10 46 81 89 31 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000067372   ⟹   ENSRNOP00000059880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1232,743,942 - 232,750,431 (+)Ensembl
mRatBN7.2 Ensembl1223,317,642 - 223,324,131 (+)Ensembl
Rnor_6.0 Ensembl1243,662,823 - 243,669,312 (+)Ensembl
RefSeq Acc Id: NM_001107597   ⟹   NP_001101067
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,743,942 - 232,750,431 (+)NCBI
mRatBN7.21223,317,642 - 223,324,131 (+)NCBI
Rnor_6.01243,662,823 - 243,669,312 (+)NCBI
Rnor_5.01250,921,208 - 250,927,697 (+)NCBI
RGSC_v3.41229,114,066 - 229,120,555 (+)RGD
Celera1220,519,356 - 220,525,845 (+)RGD
Sequence:
RefSeq Acc Id: XM_008760307   ⟹   XP_008758529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,743,935 - 232,749,241 (+)NCBI
mRatBN7.21223,317,543 - 223,322,945 (+)NCBI
Rnor_6.01243,662,819 - 243,668,068 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039080293   ⟹   XP_038936221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,743,936 - 232,750,426 (+)NCBI
mRatBN7.21223,317,568 - 223,324,128 (+)NCBI
RefSeq Acc Id: XM_063264772   ⟹   XP_063120842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,746,924 - 232,750,426 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101067 (Get FASTA)   NCBI Sequence Viewer  
  XP_008758529 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936221 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120842 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13054 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000059880
  ENSRNOP00000059880.2
RefSeq Acc Id: NP_001101067   ⟸   NM_001107597
- UniProtKB: D4A098 (UniProtKB/TrEMBL),   A6I0S3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758529   ⟸   XM_008760307
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000059880   ⟸   ENSRNOT00000067372
RefSeq Acc Id: XP_038936221   ⟸   XM_039080293
- Peptide Label: isoform X1
- UniProtKB: D4A098 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120842   ⟸   XM_063264772
- Peptide Label: isoform X2
Protein Domains
DM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A098-F1-model_v2 AlphaFold D4A098 1-560 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690834
Promoter ID:EPDNEW_R1359
Type:single initiation site
Name:Dmrt2_1
Description:doublesex and mab-3 related transcription factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01243,662,828 - 243,662,888EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309047 AgrOrtholog
BioCyc Gene G2FUF-56068 BioCyc
Ensembl Genes ENSRNOG00000016301 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067372 ENTREZGENE
  ENSRNOT00000067372.3 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1040.10 UniProtKB/TrEMBL
InterPro DM_DNA-bd UniProtKB/TrEMBL
  DM_DNA-bd_sf UniProtKB/TrEMBL
  DMRT/dsx/mab-3 UniProtKB/TrEMBL
KEGG Report rno:309430 UniProtKB/TrEMBL
NCBI Gene 309430 ENTREZGENE
PANTHER DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2 UniProtKB/TrEMBL
  PTHR12322 UniProtKB/TrEMBL
Pfam PF00751 UniProtKB/TrEMBL
PhenoGen Dmrt2 PhenoGen
PROSITE DM_1 UniProtKB/TrEMBL
  DM_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016301 RatGTEx
SMART SM00301 UniProtKB/TrEMBL
Superfamily-SCOP DM_DNA_bd UniProtKB/TrEMBL
UniProt A6I0S3 ENTREZGENE, UniProtKB/TrEMBL
  D4A098 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Dmrt2  doublesex and mab-3 related transcription factor 2   Dmrt2_predicted  doublesex and mab-3 related transcription factor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dmrt2_predicted  doublesex and mab-3 related transcription factor 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED