Hltf (helicase-like transcription factor) - Rat Genome Database

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Gene: Hltf (helicase-like transcription factor) Rattus norvegicus
Analyze
Symbol: Hltf
Name: helicase-like transcription factor
RGD ID: 1309031
Description: Predicted to enable ATP-dependent activity, acting on DNA; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including mRNA transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human HLTF (helicase like transcription factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC295568; Smarca3; Snf2l3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82104,478,725 - 104,538,531 (+)NCBIGRCr8
mRatBN7.22102,549,724 - 102,609,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2109,063,231 - 109,122,470 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02107,184,391 - 107,243,629 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02102,148,291 - 102,207,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02104,854,571 - 104,914,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2104,854,572 - 104,914,173 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02124,574,548 - 124,634,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,202,487 - 105,262,107 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12105,148,839 - 105,205,382 (+)NCBI
Celera297,919,578 - 97,979,241 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9427542   PMID:18316726   PMID:18719106   PMID:19723507   PMID:19946888   PMID:21396873   PMID:21507896   PMID:22658674   PMID:25023518   PMID:26350214  


Genomics

Comparative Map Data
Hltf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82104,478,725 - 104,538,531 (+)NCBIGRCr8
mRatBN7.22102,549,724 - 102,609,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2109,063,231 - 109,122,470 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02107,184,391 - 107,243,629 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02102,148,291 - 102,207,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02104,854,571 - 104,914,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2104,854,572 - 104,914,173 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02124,574,548 - 124,634,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,202,487 - 105,262,107 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12105,148,839 - 105,205,382 (+)NCBI
Celera297,919,578 - 97,979,241 (+)NCBICelera
Cytogenetic Map2q24NCBI
HLTF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383149,030,063 - 149,086,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3149,030,127 - 149,086,554 (-)EnsemblGRCh38hg38GRCh38
GRCh373148,747,850 - 148,804,320 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363150,230,594 - 150,287,031 (-)NCBINCBI36Build 36hg18NCBI36
Build 343150,230,611 - 150,287,015NCBI
Celera3147,158,179 - 147,214,609 (-)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3146,119,870 - 146,176,257 (-)NCBIHuRef
CHM1_13148,710,947 - 148,767,418 (-)NCBICHM1_1
T2T-CHM13v2.03151,780,777 - 151,837,250 (-)NCBIT2T-CHM13v2.0
Hltf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39320,111,959 - 20,172,655 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl320,111,975 - 20,172,654 (+)EnsemblGRCm39 Ensembl
GRCm38320,057,808 - 20,118,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl320,057,811 - 20,118,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv37319,957,811 - 20,018,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36320,249,962 - 20,310,527 (+)NCBIMGSCv36mm8
Celera320,047,166 - 20,107,713 (+)NCBICelera
Cytogenetic Map3A2NCBI
cM Map36.15NCBI
Hltf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554748,412,136 - 8,486,752 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554748,411,912 - 8,488,938 (+)NCBIChiLan1.0ChiLan1.0
HLTF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13153,632,319 - 153,688,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3153,632,319 - 153,688,951 (-)Ensemblpanpan1.1panPan2
HLTF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12343,868,896 - 43,918,616 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2343,870,939 - 43,918,436 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2343,734,282 - 43,783,354 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02344,498,185 - 44,547,255 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2344,498,189 - 44,547,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12344,086,465 - 44,136,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02344,134,925 - 44,184,505 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02344,389,026 - 44,438,712 (-)NCBIUU_Cfam_GSD_1.0
Hltf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560283,155,157 - 83,202,437 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365196,531,571 - 6,582,081 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365196,531,549 - 6,579,724 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HLTF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1389,261,205 - 89,333,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11389,261,199 - 89,333,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21397,254,690 - 97,326,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HLTF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11541,621,349 - 41,676,185 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1541,621,456 - 41,674,120 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604114,463,704 - 14,518,550 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hltf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473026,257,609 - 26,333,936 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473026,255,426 - 26,334,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hltf
447 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:241
Interacting mature miRNAs:293
Transcripts:ENSRNOT00000064828
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)281018907126018907Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)282345893130923501Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)238573329122609194Rat
1598862Glom9Glomerulus QTL 93.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)292337601137337601Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
1598863Cm65Cardiac mass QTL 652.3heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)292337601137337601Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)276539322102785628Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
2300165Bmd49Bone mineral density QTL 494.80.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)288862519133862519Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
2300170Bmd45Bone mineral density QTL 4512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)288862519133862519Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
2300185Bmd46Bone mineral density QTL 468.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)288862519133862519Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)280270434125270434Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
7207808Bmd89Bone mineral density QTL 894.1femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)288862519133862519Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
RH127313  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22102,608,853 - 102,609,044 (+)MAPPERmRatBN7.2
Rnor_6.02104,913,700 - 104,913,890NCBIRnor6.0
Rnor_5.02124,633,751 - 124,633,941UniSTSRnor5.0
RGSC_v3.42105,261,622 - 105,261,812UniSTSRGSC3.4
Celera297,978,756 - 97,978,946UniSTS
RH 3.4 Map2729.6UniSTS
Cytogenetic Map2q24UniSTS
AU047370  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22102,560,975 - 102,561,122 (+)MAPPERmRatBN7.2
Rnor_6.02104,865,822 - 104,865,972NCBIRnor6.0
Rnor_5.02124,585,798 - 124,585,948UniSTSRnor5.0
RGSC_v3.42105,213,737 - 105,213,887UniSTSRGSC3.4
Celera297,930,809 - 97,930,973UniSTS
Cytogenetic Map2q24UniSTS
RH140388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26116,967,420 - 116,967,609 (+)MAPPERmRatBN7.2
mRatBN7.22102,609,025 - 102,609,211 (+)MAPPERmRatBN7.2
Rnor_6.02104,913,872 - 104,914,057NCBIRnor6.0
Rnor_6.06121,687,222 - 121,687,410NCBIRnor6.0
Rnor_5.06130,907,420 - 130,907,608UniSTSRnor5.0
Rnor_5.02124,633,923 - 124,634,108UniSTSRnor5.0
RGSC_v3.46121,856,966 - 121,857,154UniSTSRGSC3.4
RGSC_v3.42105,261,794 - 105,261,979UniSTSRGSC3.4
Celera297,978,928 - 97,979,113UniSTS
Celera6114,547,864 - 114,548,052UniSTS
Cytogenetic Map2q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000064828   ⟹   ENSRNOP00000060341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)Ensembl
Rnor_6.0 Ensembl2104,854,572 - 104,914,173 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090912   ⟹   ENSRNOP00000069487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)Ensembl
Rnor_6.0 Ensembl2104,854,580 - 104,912,627 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106667   ⟹   ENSRNOP00000092944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)Ensembl
RefSeq Acc Id: NM_001106478   ⟹   NP_001099948
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82104,478,765 - 104,538,378 (+)NCBI
mRatBN7.22102,549,724 - 102,609,339 (+)NCBI
Rnor_6.02104,854,572 - 104,914,185 (+)NCBI
Rnor_5.02124,574,548 - 124,634,389 (+)NCBI
RGSC_v3.42105,202,487 - 105,262,107 (+)RGD
Celera297,919,578 - 97,979,241 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232175   ⟹   XP_006232237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82104,478,725 - 104,538,531 (+)NCBI
mRatBN7.22102,549,734 - 102,609,492 (+)NCBI
Rnor_6.02104,854,571 - 104,914,338 (+)NCBI
Rnor_5.02124,574,548 - 124,634,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232176   ⟹   XP_006232238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82104,478,725 - 104,538,531 (+)NCBI
mRatBN7.22102,549,734 - 102,609,492 (+)NCBI
Rnor_6.02104,854,572 - 104,914,338 (+)NCBI
Rnor_5.02124,574,548 - 124,634,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232177   ⟹   XP_006232239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82104,478,775 - 104,538,531 (+)NCBI
mRatBN7.22102,549,734 - 102,609,492 (+)NCBI
Rnor_6.02104,854,571 - 104,914,338 (+)NCBI
Rnor_5.02124,574,548 - 124,634,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039102120   ⟹   XP_038958048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82104,478,775 - 104,538,531 (+)NCBI
mRatBN7.22102,549,734 - 102,609,492 (+)NCBI
RefSeq Acc Id: NP_001099948   ⟸   NM_001106478
- UniProtKB: D3ZMQ9 (UniProtKB/TrEMBL),   A6IHC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232237   ⟸   XM_006232175
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232239   ⟸   XM_006232177
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006232238   ⟸   XM_006232176
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVH5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069487   ⟸   ENSRNOT00000090912
Ensembl Acc Id: ENSRNOP00000060341   ⟸   ENSRNOT00000064828
RefSeq Acc Id: XP_038958048   ⟸   XM_039102120
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000092944   ⟸   ENSRNOT00000106667
Protein Domains
Helicase ATP-binding   Helicase C-terminal   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVH5-F1-model_v2 AlphaFold A0A0G2JVH5 1-1003 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691262
Promoter ID:EPDNEW_R1782
Type:initiation region
Name:Hltf_1
Description:helicase-like transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02104,854,601 - 104,854,661EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309031 AgrOrtholog
BioCyc Gene G2FUF-53606 BioCyc
Ensembl Genes ENSRNOG00000000082 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064828.4 UniProtKB/TrEMBL
  ENSRNOT00000090912.2 UniProtKB/TrEMBL
  ENSRNOT00000106667.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.30.70.2330 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD-like_helicase UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HIP116_Rad5p_N UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  SNF2_RAD54_helicase_TF UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:295568 UniProtKB/TrEMBL
NCBI Gene 295568 ENTREZGENE
PANTHER HELICASE-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION TERMINATION FACTOR 2-RELATED UniProtKB/TrEMBL
Pfam Helicase_C UniProtKB/TrEMBL
  HIRAN UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/TrEMBL
PhenoGen Hltf PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000082 RatGTEx
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  HIRAN UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JVH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF43 ENTREZGENE, UniProtKB/TrEMBL
  A6IHC7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMQ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Hltf  helicase-like transcription factor  Smarca3_predicted  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Smarca3_predicted  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED