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Gene: Cldn23 (claudin 23) Rattus norvegicus

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Symbol:

Cldn23

Name:

claudin 23

RGD ID:

1309001

Description:

Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in anchoring junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN23 (claudin 23); PARTICIPATES IN hepatitis C pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

claudin-23; LOC290789; MGC124737

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CLDN23 (claudin 23)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cldn23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cldn23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CLDN23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CLDN23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cldn23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CLDN23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CLDN23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cldn23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cldn23 (claudin 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CLDN23 (claudin 23)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cldn23 (claudin 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cldn23a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cldn23.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cldn23	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cldn23	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	63,117,045 - 63,118,769 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	63,116,781 - 63,118,957 (+)	Ensembl				GRCr8
mRatBN7.2	16	56,413,677 - 56,415,401 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	56,413,381 - 56,415,523 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	61,731,329 - 61,733,053 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	65,145,310 - 65,147,034 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	60,365,289 - 60,367,013 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	59,988,603 - 59,990,327 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	59,988,603 - 59,990,326 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	59,664,248 - 59,665,972 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	60,109,161 - 60,110,885 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	54,465,687 - 54,467,411 (+)	NCBI		Celera
RGSC_v3.1	16	60,109,337 - 60,110,225 (+)	NCBI
Cytogenetic Map	16	q12.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atopic dermatitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrotoluene (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

alpha-Zearalanol (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

caffeine (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

CU-O LINKAGE (ISO)

Cuprizon (EXP)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen peroxide (ISO)

iron dichloride (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lidocaine (EXP)

manganese atom (EXP)

manganese(0) (EXP)

manganese(II) chloride (EXP)

menadione (ISO)

methotrexate (ISO)

methylmercury chloride (ISO)

ochratoxin A (ISO)

orphenadrine (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercitrin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular protein localization (ISO)

tight junction organization (ISO)

Cellular Component

bicellular tight junction (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

protein binding (ISO)

structural molecule activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Tight junction defects in patients with atopic dermatitis.	De Benedetto A, etal., J Allergy Clin Immunol. 2011 Mar;127(3):773-86.e1-7. doi: 10.1016/j.jaci.2010.10.018. Epub 2010 Dec 15.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:18036336

Genomics

Comparative Map Data

Cldn23
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	63,117,045 - 63,118,769 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	63,116,781 - 63,118,957 (+)	Ensembl				GRCr8
mRatBN7.2	16	56,413,677 - 56,415,401 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	56,413,381 - 56,415,523 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	61,731,329 - 61,733,053 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	65,145,310 - 65,147,034 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	60,365,289 - 60,367,013 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	59,988,603 - 59,990,327 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	59,988,603 - 59,990,326 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	59,664,248 - 59,665,972 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	60,109,161 - 60,110,885 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	54,465,687 - 54,467,411 (+)	NCBI		Celera
RGSC_v3.1	16	60,109,337 - 60,110,225 (+)	NCBI
Cytogenetic Map	16	q12.2	NCBI

CLDN23
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	8,701,937 - 8,704,096 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	8,701,937 - 8,704,096 (+)	Ensembl			hg38	GRCh38
GRCh37	8	8,559,447 - 8,561,606 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	8,597,076 - 8,599,027 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	8,597,075 - 8,599,026	NCBI
Celera	8	7,687,957 - 7,689,908 (+)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	7,484,572 - 7,486,524 (+)	NCBI		HuRef
CHM1_1	8	8,625,042 - 8,626,993 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	11,040,282 - 11,042,441 (-)	NCBI		T2T-CHM13v2.0

Cldn23
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	36,291,863 - 36,293,713 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	36,291,866 - 36,293,713 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	35,824,709 - 35,826,559 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	35,824,712 - 35,826,559 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	36,887,766 - 36,889,613 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	37,293,243 - 37,295,061 (-)	NCBI		MGSCv36	mm8
Celera	8	38,462,675 - 38,464,524 (-)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	21.21	NCBI

Cldn23
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	4,740,544 - 4,741,431 (+)	Ensembl
ChiLan1.0	NW_004955463	4,740,476 - 4,742,283 (+)	NCBI	ChiLan1.0	ChiLan1.0

CLDN23
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	25,154,107 - 25,157,483 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	1,183,110 - 1,189,309 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	10,510,323 - 10,512,467 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

CLDN23
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	35,786,709 - 35,788,430 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	36,251,918 - 36,252,704 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	37,825,184 - 37,826,910 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	16	35,925,770 - 35,926,556 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	36,487,288 - 36,489,014 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	36,606,415 - 36,608,141 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cldn23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	43,365,156 - 43,366,904 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936573	1,775,972 - 1,776,856 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936573	1,775,145 - 1,777,262 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLDN23
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	481,527 - 484,859 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	483,635 - 484,686 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	151,649 - 152,700 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CLDN23
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	10,337,815 - 10,339,906 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	10,338,791 - 10,339,672 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666052	32,054,962 - 32,057,327 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cldn23
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624839	4,719,985 - 4,720,869 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624839	4,719,208 - 4,721,734 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cldn23
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	51,249,201 - 51,251,173 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cldn23
17 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	430
Count of miRNA genes:	225
Interacting mature miRNAs:	263
Transcripts:	ENSRNOT00000015176
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	28468701	73468701	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	62414464	75736480	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	59428714	91442908	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	59428714	91442908	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	59428714	91442908	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	7	31	137	70	75	44	37	44	6	232	87	6	125	79	91	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC100630	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015176 ⟹ ENSRNOP00000015175

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	63,116,781 - 63,118,957 (+)	Ensembl
mRatBN7.2 Ensembl	16	56,413,381 - 56,415,523 (+)	Ensembl
Rnor_6.0 Ensembl	16	59,988,603 - 59,990,326 (+)	Ensembl

RefSeq Acc Id:

NM_001033062 ⟹ NP_001028234

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	63,117,045 - 63,118,769 (+)	NCBI
mRatBN7.2	16	56,413,677 - 56,415,401 (+)	NCBI
Rnor_6.0	16	59,988,603 - 59,990,327 (+)	NCBI
Rnor_5.0	16	59,664,248 - 59,665,972 (+)	NCBI
RGSC_v3.4	16	60,109,161 - 60,110,885 (+)	RGD
Celera	16	54,465,687 - 54,467,411 (+)	RGD

Sequence:

show sequence

CGGTGAGCATCGCTGCCACCCAGCCCGGCAACCTCGCAGACTTGAGGACCCGGTGCGCCGCGGA
GCAGCCACAGCTGCTGGGGACCCACGAGGCTACGCGGGATGCGGACGCCGGTGGTGATGACGCT
GGGCATGGTGCTCACGCCCTGTGGGTTGCTGCTCAATCTCGTCAGTACACTGGCCCCGGGCTGG
CGGCTGTTGAAGGGCTTTCGGGACCAGCCAGTGGACGTGGTGCTGTACCAGGGGCTGTGGGACA
TATGTCGCGAGCAGAGCAGCCGCGAGCGCGAGTGCGGCCAGCCGGACCAGTGGAACTACTTCGG
GACTCAGCCTGTGCAGGTGGCCCGGGGACTCATGATCACTTCACTGGCCACTACCGCCCTAGGG
CTGCTGTTGGCTTCGCTCGGCGTGCGCTGTTGGCAAGAAGAGCCCCACTTCGGGCTAGCGGGCC
TCTCGGGGGTTGTGCTTTTCGCCGCCGGCCTCTTCAGCCTCATCCCCGTCTCCTGGTATAACCA
CTTCTTGGCAGATCCTGACGTCCTGGCTGCCCCGGCCCAACCGGTCACTGTGCAGGTCAGCTAC
AGTCTGGTGCTGGGCTACCTAGGCAGTTGCCTGCTGTTGTTGGGCGGTTTCTCGCTGGCGCTCA
GCTTTGCGCCCTGGTGTGAAGAGCGTTGTTGCCGCTGTCGCAAGGCGCCCCCAGCAGGCCCACG
CCGCAGCAGCATCAGCACCGTCTACGTGGACTGGCCGGAACCCGCACTCACACCCGCCATCAAG
TACTACAGCGAGGGTCAGCATCGACCTCCTCCTGCCCAGCAAAGGGACACCGGCAAACTCAAGG
TCGGATTCCCGATGCCACGACCGCCACCCAAGGCCTACACCAACCCGATGGATGTGCTTGAGGG
AGAAGAAAAGAAGACAGCCTCCTCCCAAGACGGTTCCTCATCTCGCAGCACTCGGCCCTGCCAA
AATTCGCTGCCCTGTGACTCCGACCTGTAGACAGGGCTCAACTGAGCTCCACCTGTGGTCTGAG
GGTGACTTGAACTTCTACATGGCCAGTACATCTGCAACCAGAACCCTGGACGCCTTCCTCTAAC
TGGAGGGCAAGCCTTCCTTTCCTGGCCAAGCTCCTCTCCAGATACTAGGTTGGGTTCATTTATC
TTTTAAGGAGTTTTACTTTTTCTCTGCAGAGGGACCAGGTTTTCTGTGACAAGAGTGGGTGGCA
TTTTGCATAGTGTTAATTGCAGTAGCAACAACAAAATCTCAATCAGCCAACAGGCTTTAAGAAG
TCCTTGAAAATACAGTATTCTAAGTTACCCATGAGCCTTCACAAACATCACTCTTGAGGTGTTT
GGTTTGGTTTTGCTTTTGTCCCTGCTTCAGTCTCCAGTGAACCCAAATGGCCAAAAATGTAAGT
CTGGCTGTATTTGAAGGTTGTGCCACAAAGCCAGCTGCCTTAATGTCTTTTATGAAGTGAAGTA
ACTTGTTAACACATATTTATATTTCTCTGTGCATACATAGTATTTATCTTTTCTAATCACTTGT
TTCTGTGTAGGAGGTTGAGCTTAGTCAAGAGATTGCCTTCCAGAAGCCAGGACGATGCTACGCT
GTCCTGTTCCCTAGATACCTCACCCTGAACAGAGAGACACATTTTGTACAAAATGAACTGCTAA
GCTGCATTGGCTAAAGCCCGTATGTACATATCTTATTTATAAATAAAAATTGTAAATGTCAAAA
AAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001028234	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00631	(Get FASTA)	NCBI Sequence Viewer
	EDM09201	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015175
	ENSRNOP00000015175.3

RefSeq Acc Id:

NP_001028234 ⟸ NM_001033062

- UniProtKB:

Q497B5 (UniProtKB/TrEMBL), A6IVM1 (UniProtKB/TrEMBL), F7F879 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRTPVVMTLGMVLTPCGLLLNLVSTLAPGWRLLKGFRDQPVDVVLYQGLWDICREQSSRERECG
QPDQWNYFGTQPVQVARGLMITSLATTALGLLLASLGVRCWQEEPHFGLAGLSGVVLFAAGLFS
LIPVSWYNHFLADPDVLAAPAQPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCEERCCRC
RKAPPAGPRRSSISTVYVDWPEPALTPAIKYYSEGQHRPPPAQQRDTGKLKVGFPMPRPPPKAY
TNPMDVLEGEEKKTASSQDGSSSRSTRPCQNSLPCDSDL

hide sequence

Ensembl Acc Id:

ENSRNOP00000015175 ⟸ ENSRNOT00000015176

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q497B5-F1-model_v2	AlphaFold	Q497B5	1-295	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700131

Promoter ID:

EPDNEW_R10655

Type:

multiple initiation site

Name:

Cldn23_1

Description:

claudin 23

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	59,988,584 - 59,988,644	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309001	AgrOrtholog
BioCyc Gene	G2FUF-11176	BioCyc
Ensembl Genes	ENSRNOG00000011424	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000015176	ENTREZGENE
	ENSRNOT00000015176.6	UniProtKB/TrEMBL
Gene3D-CATH	1.20.140.150	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7938080	IMAGE-MGC_LOAD
InterPro	Claudin	UniProtKB/TrEMBL
	Claudin_CS	UniProtKB/TrEMBL
	PMP22/EMP/MP20/Claudin	UniProtKB/TrEMBL
KEGG Report	rno:290789	UniProtKB/TrEMBL
MGC_CLONE	MGC:124737	IMAGE-MGC_LOAD
NCBI Gene	290789	ENTREZGENE
PANTHER	Claudin	UniProtKB/TrEMBL
Pfam	PMP22_Claudin	UniProtKB/TrEMBL
PhenoGen	Cldn23	PhenoGen
PRINTS	CLAUDIN	UniProtKB/TrEMBL
PROSITE	CLAUDIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011424	RatGTEx
UniProt	A6IVM1	ENTREZGENE, UniProtKB/TrEMBL
	F7F879	ENTREZGENE, UniProtKB/TrEMBL
	Q497B5	ENTREZGENE
UniProt Secondary	Q497B5	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Cldn23	claudin 23	Cldn23_predicted	claudin 23 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Cldn23_predicted	claudin 23 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)