Ralgdsl1 (ral guanine nucleotide dissociation stimulator like 1) - Rat Genome Database

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Gene: Ralgdsl1 (ral guanine nucleotide dissociation stimulator like 1) Rattus norvegicus
Analyze
Symbol: Ralgdsl1
Name: ral guanine nucleotide dissociation stimulator like 1
RGD ID: 1308947
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be active in plasma membrane. Orthologous to human RGL1 (ral guanine nucleotide dissociation stimulator like 1); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289080; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; Rgl1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81367,184,402 - 67,454,019 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1367,184,402 - 67,454,019 (-)EnsemblGRCr8
mRatBN7.21364,634,489 - 64,904,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,635,246 - 64,904,191 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1367,243,711 - 67,506,393 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,520,706 - 68,799,251 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01365,781,720 - 66,050,138 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01369,909,122 - 70,174,590 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1369,909,096 - 70,174,565 (-)Ensemblrn6Rnor6.0
Rnor_5.01374,881,101 - 75,145,659 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41367,468,218 - 67,754,947 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1364,547,086 - 64,810,801 (-)NCBICelera
RGSC_v3.11367,483,775 - 67,596,194 (-)NCBI
Cytogenetic Map13q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
3',5'-cyclic AMP  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
isobutanol  (ISO)
ketoconazole  (EXP)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mocetinostat  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
permethrin  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tacedinaline  (ISO)
tamoxifen  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ralgdsl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81367,184,402 - 67,454,019 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1367,184,402 - 67,454,019 (-)EnsemblGRCr8
mRatBN7.21364,634,489 - 64,904,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,635,246 - 64,904,191 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1367,243,711 - 67,506,393 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,520,706 - 68,799,251 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01365,781,720 - 66,050,138 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01369,909,122 - 70,174,590 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1369,909,096 - 70,174,565 (-)Ensemblrn6Rnor6.0
Rnor_5.01374,881,101 - 75,145,659 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41367,468,218 - 67,754,947 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1364,547,086 - 64,810,801 (-)NCBICelera
RGSC_v3.11367,483,775 - 67,596,194 (-)NCBI
Cytogenetic Map13q21NCBI
RGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381183,636,109 - 183,928,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1183,636,085 - 183,928,532 (+)Ensemblhg38GRCh38
GRCh371183,605,244 - 183,897,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,871,831 - 182,164,289 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341180,336,876 - 180,629,322NCBI
Celera1156,716,240 - 157,008,586 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,841,067 - 155,133,408 (+)NCBIHuRef
CHM1_11185,027,897 - 185,320,329 (+)NCBICHM1_1
T2T-CHM13v2.01182,995,391 - 183,287,882 (+)NCBIT2T-CHM13v2.0
Rgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,392,513 - 152,642,056 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,392,511 - 152,642,102 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381152,516,762 - 152,766,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,516,760 - 152,766,351 (-)Ensemblmm10GRCm38
MGSCv371154,364,660 - 154,472,241 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361154,279,748 - 154,387,329 (-)NCBIMGSCv36mm8
Celera1154,937,769 - 155,046,515 (-)NCBICelera
Cytogenetic Map1G2- G3NCBI
cM Map164.85NCBI
Rgl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540622,483,336 - 22,670,537 (+)Ensembl
ChiLan1.0NW_00495540622,419,137 - 22,670,537 (+)NCBIChiLan1.0ChiLan1.0
RGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2165,790,123 - 66,081,962 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,473,320 - 65,765,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,166,090 - 159,457,883 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,323,651 - 163,614,657 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,429,258 - 163,614,657 (+)EnsemblpanPan2panpan1.1
RGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,986,304 - 17,236,549 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl717,041,296 - 17,235,193 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha716,571,833 - 16,821,876 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0716,718,212 - 16,968,704 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl716,718,185 - 16,968,890 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1716,626,490 - 16,876,720 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0716,735,857 - 16,985,375 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,866,935 - 17,116,349 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,179,408 - 88,420,192 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,026,157 - 6,175,453 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,848,338 - 125,144,253 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19124,848,358 - 125,143,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29137,178,640 - 137,472,441 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12545,444,588 - 45,730,912 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2545,444,468 - 45,568,506 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605546,660,856 - 46,947,508 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,950,327 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248149,747,154 - 10,062,828 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rgl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11031,971,460 - 32,220,470 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgdsl1
1252 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:410
Count of miRNA genes:234
Interacting mature miRNAs:287
Transcripts:ENSRNOT00000067135
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat

Markers in Region
D13Rat29  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81367,451,461 - 67,451,625 (+)Marker Load Pipeline
mRatBN7.21364,901,586 - 64,901,750 (+)MAPPERmRatBN7.2
Rnor_6.01370,172,055 - 70,172,216NCBIRnor6.0
Rnor_5.01375,143,142 - 75,143,303UniSTSRnor5.0
RGSC_v3.41367,752,436 - 67,752,598RGDRGSC3.4
RGSC_v3.41367,752,437 - 67,752,598UniSTSRGSC3.4
RGSC_v3.11367,766,517 - 67,766,678RGD
RH 3.4 Map13325.3RGD
RH 3.4 Map13325.3UniSTS
RH 2.0 Map13402.1RGD
SHRSP x BN Map1323.8399RGD
FHH x ACI Map1324.86RGD
Cytogenetic Map13q21UniSTS
D13Got43  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,854,771 - 64,854,979 (+)MAPPERmRatBN7.2
Rnor_6.01370,125,198 - 70,125,405NCBIRnor6.0
Rnor_5.01375,096,895 - 75,097,102UniSTSRnor5.0
RGSC_v3.41367,704,936 - 67,705,144RGDRGSC3.4
RGSC_v3.41367,704,937 - 67,705,144UniSTSRGSC3.4
Celera1364,761,456 - 64,761,663UniSTS
RGSC_v3.11367,719,017 - 67,719,224RGD
RH 3.4 Map13308.8UniSTS
RH 3.4 Map13308.8RGD
RH 2.0 Map13402.6RGD
Cytogenetic Map13q21UniSTS
RH134836  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,682,355 - 64,682,560 (+)MAPPERmRatBN7.2
Rnor_6.01369,956,975 - 69,957,179NCBIRnor6.0
Rnor_5.01374,928,966 - 74,929,170UniSTSRnor5.0
RGSC_v3.41367,515,321 - 67,515,525UniSTSRGSC3.4
Celera1364,594,185 - 64,594,389UniSTS
RH 3.4 Map13214.8UniSTS
Cytogenetic Map13q21UniSTS
AI169212  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,634,546 - 64,634,659 (+)MAPPERmRatBN7.2
Rnor_6.01369,909,168 - 69,909,280NCBIRnor6.0
Rnor_5.01374,881,159 - 74,881,271UniSTSRnor5.0
RGSC_v3.41367,467,512 - 67,467,624UniSTSRGSC3.4
Celera1364,546,380 - 64,546,492UniSTS
RH 3.4 Map13308.9UniSTS
Cytogenetic Map13q21UniSTS
AU048853  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81367,194,912 - 67,195,169 (+)Marker Load Pipeline
mRatBN7.21364,645,014 - 64,645,272 (+)MAPPERmRatBN7.2
Rnor_6.01369,919,636 - 69,919,893NCBIRnor6.0
Rnor_5.01374,891,627 - 74,891,884UniSTSRnor5.0
RGSC_v3.41367,477,980 - 67,478,237UniSTSRGSC3.4
Celera1364,556,862 - 64,557,119UniSTS
Cytogenetic Map13q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000067135   ⟹   ENSRNOP00000063014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1367,184,402 - 67,454,019 (-)Ensembl
mRatBN7.2 Ensembl1364,635,253 - 64,904,099 (-)Ensembl
Rnor_6.0 Ensembl1369,909,874 - 70,174,565 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083995   ⟹   ENSRNOP00000069394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1367,184,402 - 67,296,123 (-)Ensembl
mRatBN7.2 Ensembl1364,635,246 - 64,746,177 (-)Ensembl
Rnor_6.0 Ensembl1369,909,096 - 69,984,785 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098745   ⟹   ENSRNOP00000092177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1367,184,402 - 67,453,794 (-)Ensembl
mRatBN7.2 Ensembl1364,635,253 - 64,904,191 (-)Ensembl
RefSeq Acc Id: NM_001105957   ⟹   NP_001099427
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,184,402 - 67,454,019 (-)NCBI
mRatBN7.21364,634,503 - 64,904,144 (-)NCBI
Rnor_6.01369,909,874 - 70,174,565 (-)NCBI
Rnor_5.01374,881,101 - 75,145,659 (-)NCBI
RGSC_v3.41367,468,218 - 67,754,947 (-)RGD
Celera1364,547,086 - 64,810,801 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249982   ⟹   XP_006250044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,184,402 - 67,296,145 (-)NCBI
mRatBN7.21364,634,489 - 64,746,244 (-)NCBI
Rnor_6.01369,909,122 - 70,019,925 (-)NCBI
Rnor_5.01374,881,101 - 75,145,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769610   ⟹   XP_008767832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,184,402 - 67,453,875 (-)NCBI
mRatBN7.21364,634,489 - 64,904,167 (-)NCBI
Rnor_6.01369,909,122 - 70,174,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598701   ⟹   XP_017454190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,184,402 - 67,453,875 (-)NCBI
mRatBN7.21364,634,489 - 64,904,167 (-)NCBI
Rnor_6.01369,909,122 - 70,174,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090443   ⟹   XP_038946371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,188,894 - 67,453,875 (-)NCBI
mRatBN7.21364,638,996 - 64,904,170 (-)NCBI
RefSeq Acc Id: XM_063272095   ⟹   XP_063128165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,184,402 - 67,453,875 (-)NCBI
RefSeq Acc Id: XM_063272096   ⟹   XP_063128166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81367,188,895 - 67,296,200 (-)NCBI
RefSeq Acc Id: NP_001099427   ⟸   NM_001105957
- UniProtKB: D3ZS31 (UniProtKB/TrEMBL),   A6ICT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250044   ⟸   XM_006249982
- Peptide Label: isoform X2
- UniProtKB: A6ICT6 (UniProtKB/TrEMBL),   A6ICT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767832   ⟸   XM_008769610
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGN1 (UniProtKB/TrEMBL),   A6ICT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454190   ⟸   XM_017598701
- Peptide Label: isoform X1
- UniProtKB: D3ZS31 (UniProtKB/TrEMBL),   A6ICT7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063014   ⟸   ENSRNOT00000067135
Ensembl Acc Id: ENSRNOP00000069394   ⟸   ENSRNOT00000083995
RefSeq Acc Id: XP_038946371   ⟸   XM_039090443
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000092177   ⟸   ENSRNOT00000098745
RefSeq Acc Id: XP_063128165   ⟸   XM_063272095
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGN1 (UniProtKB/TrEMBL),   A6ICT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128166   ⟸   XM_063272096
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JV91 (UniProtKB/TrEMBL)
Protein Domains
N-terminal Ras-GEF   Ras-associating   Ras-GEF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JV91-F1-model_v2 AlphaFold A0A0G2JV91 1-785 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308947 AgrOrtholog
BioCyc Gene G2FUF-17906 BioCyc
Ensembl Genes ENSRNOG00000002347 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067135 ENTREZGENE
  ENSRNOT00000067135.3 UniProtKB/TrEMBL
  ENSRNOT00000083995 ENTREZGENE
  ENSRNOT00000083995.3 UniProtKB/TrEMBL
  ENSRNOT00000098745 ENTREZGENE
  ENSRNOT00000098745.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/TrEMBL
InterPro Ras-assoc UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras-like_Gua-exchang_fac_N UniProtKB/TrEMBL
  Ras_G-nucl-exch_fac_CS UniProtKB/TrEMBL
  Ras_GEF_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  RasGRF_CDC25 UniProtKB/TrEMBL
  RGL1 UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:289080 UniProtKB/TrEMBL
NCBI Gene 289080 ENTREZGENE
PANTHER PTHR23113 UniProtKB/TrEMBL
  PTHR23113:SF199 UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  RasGEF_N UniProtKB/TrEMBL
PhenoGen Ralgdsl1 PhenoGen
PROSITE PS50200 UniProtKB/TrEMBL
  RASGEF UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
  RASGEF_NTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002347 RatGTEx
SMART RasGEF UniProtKB/TrEMBL
  RasGEFN UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP Ras_GEF UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A0G2JV91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGN1 ENTREZGENE, UniProtKB/TrEMBL
  A6ICT6 ENTREZGENE, UniProtKB/TrEMBL
  A6ICT7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZS31 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-26 Ralgdsl1  ral guanine nucleotide dissociation stimulator like 1  Rgl1  ral guanine nucleotide dissociation stimulator like 1  Symbol changed 629549 APPROVED
2023-01-16 Rgl1  ral guanine nucleotide dissociation stimulator like 1  Rgl1  ral guanine nucleotide dissociation stimulator,-like 1  Name changed 629549 APPROVED
2008-04-30 Rgl1  ral guanine nucleotide dissociation stimulator,-like 1   Rgl1_predicted  ral guanine nucleotide dissociation stimulator,-like 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rgl1_predicted  ral guanine nucleotide dissociation stimulator,-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED