Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hm13 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of H13 mRNA] | CTD | PMID:22206623 | Hm13 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | H13 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of H13 mRNA | CTD | PMID:22206623 | Hm13 | Rat | 17beta-estradiol | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of HM13 mRNA | CTD | PMID:16705744 | Hm13 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of HM13 mRNA | CTD | PMID:29581250 | Hm13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | H13 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of H13 mRNA | CTD | PMID:19933214 | Hm13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | H13 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of H13 mRNA | CTD | PMID:21570461 | Hm13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of H13 mRNA; Tetrachlorodibenzodioxin results in increased expression of HM13 more ... | CTD | PMID:18796159|PMID:21215274|PMID:33387578 | Hm13 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | H13 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of H13 mRNA | CTD | PMID:26251327 | Hm13 | Rat | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | H13 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of H13 promoter | CTD | PMID:26251327 | Hm13 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of HM13 protein | CTD | PMID:34915118 | Hm13 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Hm13 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | H13 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of H13 mRNA | CTD | PMID:18648102 | Hm13 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Hm13 | Rat | 5-fluorouracil | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | Fluorouracil affects the expression of HM13 mRNA | CTD | PMID:16584549 | Hm13 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of HM13 mRNA | CTD | PMID:28959563 | Hm13 | Rat | aflatoxin B1 | increases expression | ISO | H13 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of H13 mRNA | CTD | PMID:19770486 | Hm13 | Rat | aflatoxin B1 | increases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of HM13 intron | CTD | PMID:30157460 | Hm13 | Rat | arsenous acid | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 protein | CTD | PMID:25419056 | Hm13 | Rat | arsenous acid | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 mRNA | CTD | PMID:39716349 | Hm13 | Rat | atrazine | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Atrazine results in increased expression of HM13 mRNA | CTD | PMID:22378314 | Hm13 | Rat | benzo[a]pyrene | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of HM13 mRNA | CTD | PMID:26238291 | Hm13 | Rat | benzo[a]pyrene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of HM13 3' UTR; Benzo(a)pyrene results in decreased methylation of more ... | CTD | PMID:27901495 | Hm13 | Rat | benzo[a]pyrene | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:27858113 | Hm13 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:27858113 | Hm13 | Rat | benzo[e]pyrene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of HM13 intron | CTD | PMID:30157460 | Hm13 | Rat | bis(2-ethylhexyl) phthalate | increases methylation | ISO | H13 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased methylation of H13 gene | CTD | PMID:38833407 | Hm13 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | H13 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of H13 mRNA | CTD | PMID:33754040 | Hm13 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of HM13 mRNA | CTD | PMID:25181051 | Hm13 | Rat | bisphenol A | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of HM13 protein | CTD | PMID:34186270 | Hm13 | Rat | bisphenol A | decreases expression | ISO | H13 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of H13 mRNA | CTD | PMID:39742910 | Hm13 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of HM13 mRNA | CTD | PMID:30816183|PMID:34947998 | Hm13 | Rat | bisphenol A | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol A affects the expression of HM13 mRNA | CTD | PMID:30903817 | Hm13 | Rat | bisphenol AF | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of HM13 protein | CTD | PMID:34186270 | Hm13 | Rat | Bisphenol B | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of HM13 protein | CTD | PMID:34186270 | Hm13 | Rat | bisphenol F | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of HM13 protein | CTD | PMID:34186270 | Hm13 | Rat | cadmium dichloride | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of HM13 mRNA | CTD | PMID:26472689|PMID:38568856 | Hm13 | Rat | carbon nanotube | increases expression | ISO | H13 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of H13 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Hm13 | Rat | chlorpyrifos | increases expression | ISO | H13 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of H13 mRNA | CTD | PMID:37019170 | Hm13 | Rat | chrysene | decreases expression | ISO | H13 (Mus musculus) | 6480464 | chrysene results in decreased expression of H13 mRNA | CTD | PMID:26377693 | Hm13 | Rat | chrysene | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:27858113 | Hm13 | Rat | clofibrate | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of H13 mRNA | CTD | PMID:17585979 | Hm13 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of H13 mRNA | CTD | PMID:17602206 | Hm13 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of HM13 mRNA | CTD | PMID:24386269 | Hm13 | Rat | cyclophosphamide | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Cyclophosphamide results in decreased expression of H13 mRNA | CTD | PMID:15331540 | Hm13 | Rat | cyclosporin A | increases expression | ISO | H13 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of H13 mRNA | CTD | PMID:19770486 | Hm13 | Rat | cyclosporin A | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of HM13 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:25562108|PMID:27989131 | Hm13 | Rat | decabromodiphenyl ether | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | decabromobiphenyl ether affects the expression of HM13 mRNA | CTD | PMID:24834073 | Hm13 | Rat | dexamethasone | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Hm13 | Rat | diarsenic trioxide | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 protein | CTD | PMID:25419056 | Hm13 | Rat | diarsenic trioxide | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 mRNA | CTD | PMID:39716349 | Hm13 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of HM13 mRNA | CTD | PMID:36653537 | Hm13 | Rat | diuron | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Diuron results in decreased expression of HM13 mRNA | CTD | PMID:35967413 | Hm13 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of HM13 mRNA | CTD | PMID:29391264 | Hm13 | Rat | epoxiconazole | decreases expression | ISO | H13 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of H13 mRNA | CTD | PMID:35436446 | Hm13 | Rat | fenthion | increases expression | ISO | H13 (Mus musculus) | 6480464 | Fenthion results in increased expression of H13 mRNA | CTD | PMID:34813904 | Hm13 | Rat | folic acid | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of H13 mRNA] | CTD | PMID:22206623 | Hm13 | Rat | folic acid | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of H13 mRNA | CTD | PMID:25629700 | Hm13 | Rat | FR900359 | increases phosphorylation | ISO | HM13 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of HM13 protein | CTD | PMID:37730182 | Hm13 | Rat | genistein | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Genistein results in decreased expression of HM13 mRNA | CTD | PMID:16705744 | Hm13 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of HM13 mRNA | CTD | PMID:24136188 | Hm13 | Rat | glyphosate | affects methylation | ISO | HM13 (Homo sapiens) | 6480464 | Glyphosate affects the methylation of HM13 gene | CTD | PMID:35377194 | Hm13 | Rat | indometacin | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Hm13 | Rat | isoniazide | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Isoniazid results in decreased expression of HM13 protein | CTD | PMID:40015660 | Hm13 | Rat | ivermectin | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of HM13 protein | CTD | PMID:32959892 | Hm13 | Rat | lead(0) | decreases methylation | ISO | H13 (Mus musculus) | 6480464 | Lead results in decreased methylation of H13 gene | CTD | PMID:38833407 | Hm13 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of HM13 mRNA | CTD | PMID:24136188 | Hm13 | Rat | methapyrilene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of HM13 intron | CTD | PMID:30157460 | Hm13 | Rat | methidathion | increases expression | ISO | H13 (Mus musculus) | 6480464 | methidathion results in increased expression of H13 mRNA | CTD | PMID:34813904 | Hm13 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of H13 mRNA | CTD | PMID:17602206 | Hm13 | Rat | nickel atom | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Nickel results in increased expression of HM13 mRNA | CTD | PMID:24768652 | Hm13 | Rat | okadaic acid | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of HM13 mRNA | CTD | PMID:38832940 | Hm13 | Rat | ozone | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of HM13 mRNA | CTD | PMID:35430440 | Hm13 | Rat | paracetamol | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of HM13 mRNA | CTD | PMID:29067470 | Hm13 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of HM13 mRNA | CTD | PMID:33387578 | Hm13 | Rat | paraquat | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Paraquat results in decreased expression of H13 mRNA | CTD | PMID:21371552 | Hm13 | Rat | phenobarbital | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of H13 mRNA | CTD | PMID:23091169 | Hm13 | Rat | pirinixic acid | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Hm13 | Rat | pirinixic acid | decreases expression | ISO | H13 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of H13 mRNA | CTD | PMID:23811191 | Hm13 | Rat | resveratrol | increases expression | ISO | H13 (Mus musculus) | 6480464 | resveratrol results in increased expression of H13 protein | CTD | PMID:25505154 | Hm13 | Rat | SB 431542 | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of HM13 more ... | CTD | PMID:37664457 | Hm13 | Rat | silicon dioxide | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of HM13 mRNA | CTD | PMID:25895662 | Hm13 | Rat | silver atom | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Silver results in decreased expression of H13 mRNA | CTD | PMID:27131904 | Hm13 | Rat | silver(0) | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Silver results in decreased expression of H13 mRNA | CTD | PMID:27131904 | Hm13 | Rat | sodium arsenite | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of HM13 mRNA | CTD | PMID:38568856 | Hm13 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of H13 mRNA | CTD | PMID:19281266 | Hm13 | Rat | sulindac sulfide | affects binding | ISO | HM13 (Homo sapiens) | 6480464 | sulindac sulfide binds to HM13 protein | CTD | PMID:17932033 | Hm13 | Rat | sulindac sulfide | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | sulindac sulfide inhibits the reaction [L 685458 binds to HM13 protein] | CTD | PMID:17932033 | Hm13 | Rat | testosterone | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane inhibits the reaction [Testosterone deficiency results in decreased expression of H13 mRNA] | CTD | PMID:33848595 | Hm13 | Rat | testosterone | decreases expression | ISO | H13 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of H13 mRNA | CTD | PMID:33848595 | Hm13 | Rat | tetraphene | multiple interactions | ISO | H13 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:27858113 | Hm13 | Rat | thapsigargin | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of HM13 mRNA | CTD | PMID:22378314 | Hm13 | Rat | theophylline | affects binding | ISO | HM13 (Homo sapiens) | 6480464 | Theophylline binds to HM13 protein | CTD | PMID:18951874 | Hm13 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of HM13 mRNA | CTD | PMID:23411599 | Hm13 | Rat | titanium dioxide | increases expression | ISO | H13 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of H13 mRNA | CTD | PMID:27760801 | Hm13 | Rat | titanium dioxide | decreases methylation | ISO | H13 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of H13 gene | CTD | PMID:35295148 | Hm13 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of HM13 mRNA | CTD | PMID:33387578 | Hm13 | Rat | triphenyl phosphate | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of HM13 mRNA | CTD | PMID:37042841 | Hm13 | Rat | triptonide | increases expression | ISO | H13 (Mus musculus) | 6480464 | triptonide results in increased expression of H13 mRNA | CTD | PMID:33045310 | Hm13 | Rat | tunicamycin | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of HM13 mRNA | CTD | PMID:22378314 | Hm13 | Rat | valproic acid | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of HM13 mRNA | CTD | PMID:23179753 | Hm13 | Rat | valproic acid | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of HM13 mRNA | CTD | PMID:25979313 | |






















