Akap10 (A-kinase anchoring protein 10) - Rat Genome Database

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Pathways
Gene: Akap10 (A-kinase anchoring protein 10) Rattus norvegicus
Analyze
Symbol: Akap10
Name: A-kinase anchoring protein 10
RGD ID: 1308869
Description: Predicted to enable protein kinase A binding activity. Predicted to be involved in intracellular protein localization. Predicted to be located in cytoplasm and membrane. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrion and plasma membrane. Orthologous to human AKAP10 (A-kinase anchoring protein 10); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A kinase (PRKA) anchor protein 10; A kinase anchor protein 10; A kinase anchor protein 10, mitochondrial; A-kinase anchor protein 10, mitochondrial; D-akap2; Dual specific A kinase anchoring protein 2; LOC360540
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,044,819 - 47,108,153 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1047,044,819 - 47,108,203 (-)EnsemblGRCr8
mRatBN7.21046,545,371 - 46,608,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,551,532 - 46,608,769 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1051,248,531 - 51,311,754 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,739,062 - 50,802,283 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,242,473 - 46,305,700 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,150,902 - 48,210,074 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,150,902 - 48,210,074 (-)Ensemblrn6Rnor6.0
Rnor_5.01047,937,683 - 48,001,356 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41048,031,107 - 48,087,922 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1045,798,800 - 45,855,285 (-)NCBICelera
RGSC_v3.11048,075,066 - 48,101,518 (-)NCBI
Cytogenetic Map10q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A-kinase anchoring proteins: from protein complexes to physiology and disease. Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
Additional References at PubMed
PMID:11248059   PMID:12477932   PMID:14651853   PMID:17081990   PMID:18614015   PMID:25097019  


Genomics

Comparative Map Data
Akap10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,044,819 - 47,108,153 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1047,044,819 - 47,108,203 (-)EnsemblGRCr8
mRatBN7.21046,545,371 - 46,608,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,551,532 - 46,608,769 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1051,248,531 - 51,311,754 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,739,062 - 50,802,283 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,242,473 - 46,305,700 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,150,902 - 48,210,074 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,150,902 - 48,210,074 (-)Ensemblrn6Rnor6.0
Rnor_5.01047,937,683 - 48,001,356 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41048,031,107 - 48,087,922 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1045,798,800 - 45,855,285 (-)NCBICelera
RGSC_v3.11048,075,066 - 48,101,518 (-)NCBI
Cytogenetic Map10q22NCBI
AKAP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381719,904,302 - 19,977,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1719,904,302 - 19,978,343 (-)Ensemblhg38GRCh38
GRCh371719,807,615 - 19,881,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,749,341 - 19,821,721 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341719,749,343 - 19,821,721NCBI
Celera1717,222,124 - 17,295,198 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1719,186,622 - 19,259,887 (-)NCBIHuRef
CHM1_11719,816,578 - 19,889,916 (-)NCBICHM1_1
T2T-CHM13v2.01719,852,961 - 19,926,536 (-)NCBIT2T-CHM13v2.0
Akap10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,756,029 - 61,821,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,762,133 - 61,821,078 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381161,865,203 - 61,930,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,871,307 - 61,930,252 (-)Ensemblmm10GRCm38
MGSCv371161,684,809 - 61,743,728 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361161,687,502 - 61,746,421 (-)NCBIMGSCv36mm8
MGSCv361162,301,085 - 62,361,341 (-)NCBIMGSCv36mm8
Celera1168,653,621 - 68,654,049 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Akap10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955467926,508 - 990,753 (-)Ensembl
ChiLan1.0NW_004955467919,207 - 990,753 (-)NCBIChiLan1.0ChiLan1.0
AKAP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,889,409 - 54,975,328 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,701,183 - 59,787,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,150,628 - 31,226,569 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,297,164 - 36,372,087 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,297,164 - 36,372,087 (+)EnsemblpanPan2panpan1.1
AKAP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1540,242,709 - 40,333,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl540,245,770 - 40,329,982 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha540,388,840 - 40,474,407 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0540,352,790 - 40,438,407 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl540,355,978 - 40,437,939 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1540,324,380 - 40,409,956 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0540,269,866 - 40,355,416 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,462,609 - 40,548,188 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Akap10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560258,792,417 - 58,865,444 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936821946,751 - 1,018,072 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936821946,761 - 1,019,488 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,732,123 - 59,789,131 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11259,732,317 - 59,782,422 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AKAP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,455,422 - 18,538,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,453,093 - 18,538,041 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660592,298,073 - 2,379,728 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248496,221,551 - 6,300,264 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248496,221,655 - 6,306,497 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Akap10
412 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:320
Count of miRNA genes:194
Interacting mature miRNAs:240
Transcripts:ENSRNOT00000003871
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003871   ⟹   ENSRNOP00000003871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,051,287 - 47,108,153 (-)Ensembl
mRatBN7.2 Ensembl1046,551,532 - 46,608,745 (-)Ensembl
Rnor_6.0 Ensembl1048,150,902 - 48,210,074 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094101   ⟹   ENSRNOP00000090534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,057,442 - 47,096,105 (-)Ensembl
mRatBN7.2 Ensembl1046,557,994 - 46,596,661 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108493   ⟹   ENSRNOP00000084439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,044,819 - 47,108,153 (-)Ensembl
mRatBN7.2 Ensembl1046,551,532 - 46,604,203 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109923   ⟹   ENSRNOP00000087715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1046,551,532 - 46,604,203 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117070   ⟹   ENSRNOP00000106225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,044,819 - 47,103,561 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119471   ⟹   ENSRNOP00000085194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,044,819 - 47,108,203 (-)Ensembl
mRatBN7.2 Ensembl1046,551,532 - 46,608,769 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000171845   ⟹   ENSRNOP00000107088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1047,044,819 - 47,101,985 (-)Ensembl
RefSeq Acc Id: NM_001114606   ⟹   NP_001108078
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,044,819 - 47,108,153 (-)NCBI
mRatBN7.21046,545,371 - 46,608,730 (-)NCBI
Rnor_6.01048,150,902 - 48,210,074 (-)NCBI
Rnor_5.01047,937,683 - 48,001,356 (-)NCBI
RGSC_v3.41048,031,107 - 48,087,922 (-)RGD
Celera1045,798,800 - 45,855,285 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001108078 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81953 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003871.6
  ENSRNOP00000084439
  ENSRNOP00000084439.2
  ENSRNOP00000085194.2
  ENSRNOP00000090534.1
  ENSRNOP00000106225.1
  ENSRNOP00000107088.1
RefSeq Acc Id: NP_001108078   ⟸   NM_001114606
- UniProtKB: F1LNB3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003871   ⟸   ENSRNOT00000003871
Ensembl Acc Id: ENSRNOP00000084439   ⟸   ENSRNOT00000108493
Ensembl Acc Id: ENSRNOP00000090534   ⟸   ENSRNOT00000094101
Ensembl Acc Id: ENSRNOP00000085194   ⟸   ENSRNOT00000119471
Ensembl Acc Id: ENSRNOP00000087715   ⟸   ENSRNOT00000109923
Ensembl Acc Id: ENSRNOP00000106225   ⟸   ENSRNOT00000117070
Ensembl Acc Id: ENSRNOP00000107088   ⟸   ENSRNOT00000171845
Protein Domains
RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LNB3-F1-model_v2 AlphaFold F1LNB3 1-662 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697267
Promoter ID:EPDNEW_R7792
Type:multiple initiation site
Name:Akap10_1
Description:A-kinase anchoring protein 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01048,210,053 - 48,210,113EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308869 AgrOrtholog
BioCyc Gene G2FUF-24787 BioCyc
Ensembl Genes ENSRNOG00000002899 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003871.6 UniProtKB/TrEMBL
  ENSRNOT00000094101.2 UniProtKB/TrEMBL
  ENSRNOT00000108493 ENTREZGENE
  ENSRNOT00000108493.2 UniProtKB/TrEMBL
  ENSRNOT00000117070.2 UniProtKB/TrEMBL
  ENSRNOT00000119471.2 UniProtKB/TrEMBL
  ENSRNOT00000171845.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122794 IMAGE-MGC_LOAD
InterPro AKAP10_AKB_dom UniProtKB/TrEMBL
  Cell_Polariz_PKAAnc UniProtKB/TrEMBL
  Regulat_G_prot_signal_superfam UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
MGC_CLONE MGC:94043 IMAGE-MGC_LOAD
NCBI Gene 360540 ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL UniProtKB/TrEMBL
  A-KINASE ANCHOR PROTEINS UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PhenoGen Akap10 PhenoGen
PROSITE RGS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002899 RatGTEx
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP Regulat_G_prot_signal_superfam UniProtKB/TrEMBL
UniProt A0A8I5ZY40_RAT UniProtKB/TrEMBL
  A0A8I5ZZM1_RAT UniProtKB/TrEMBL
  A0A8I6ABZ8_RAT UniProtKB/TrEMBL
  A0ABK0LWT6_RAT UniProtKB/TrEMBL
  A0ABK0LX81_RAT UniProtKB/TrEMBL
  F1LNB3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Akap10  A-kinase anchoring protein 10  Akap10  A kinase (PRKA) anchor protein 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Akap10  A kinase (PRKA) anchor protein 10  Akap10_predicted  A kinase (PRKA) anchor protein 10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Akap10_predicted  A kinase (PRKA) anchor protein 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED