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Gene: Pdzrn4 (PDZ domain containing RING finger 4) Rattus norvegicus

Analyze

Symbol:

Pdzrn4

Name:

PDZ domain containing RING finger 4

RGD ID:

1308860

Description:

Orthologous to human PDZRN4 (PDZ domain containing ring finger 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC315250; PDZ domain-containing RING finger protein 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	125,696,448 - 125,844,965 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	125,696,448 - 125,844,965 (+)	Ensembl				GRCr8
mRatBN7.2	7	123,816,961 - 123,965,491 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	123,816,961 - 123,965,491 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	125,591,457 - 125,741,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	127,817,303 - 127,967,004 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	127,739,085 - 127,888,785 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	133,856,101 - 134,004,250 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	133,856,101 - 134,004,250 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	133,539,221 - 133,687,546 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	131,114,108 - 131,265,328 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	120,218,741 - 120,366,960 (+)	NCBI		Celera
RGSC_v3.1	7	131,190,625 - 131,341,630 (+)	NCBI
Cytogenetic Map	7	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

silicosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

CGP 52608 (ISO)

coumarin (ISO)

Cuprizon (EXP)

diarsenic trioxide (ISO)

ethanol (ISO)

ethylparaben (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel atom (ISO)

permethrin (EXP)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Pdzrn4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	125,696,448 - 125,844,965 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	125,696,448 - 125,844,965 (+)	Ensembl				GRCr8
mRatBN7.2	7	123,816,961 - 123,965,491 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	123,816,961 - 123,965,491 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	125,591,457 - 125,741,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	127,817,303 - 127,967,004 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	127,739,085 - 127,888,785 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	133,856,101 - 134,004,250 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	133,856,101 - 134,004,250 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	133,539,221 - 133,687,546 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	131,114,108 - 131,265,328 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	120,218,741 - 120,366,960 (+)	NCBI		Celera
RGSC_v3.1	7	131,190,625 - 131,341,630 (+)	NCBI
Cytogenetic Map	7	q35	NCBI

PDZRN4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	41,188,320 - 41,574,745 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	41,188,320 - 41,574,745 (+)	Ensembl			hg38	GRCh38
GRCh37	12	41,582,122 - 41,968,547 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	40,117,808 - 40,254,659 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	40,117,840 - 40,254,658	NCBI
Celera	12	40,385,466 - 40,771,197 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI
HuRef	12	38,608,491 - 38,994,159 (+)	NCBI		HuRef
CHM1_1	12	41,547,135 - 41,933,373 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	41,147,522 - 41,533,404 (+)	NCBI		T2T-CHM13v2.0

Pdzrn4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	92,294,691 - 92,669,700 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	92,294,762 - 92,669,700 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	92,396,810 - 92,771,827 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	92,396,881 - 92,771,819 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	92,227,241 - 92,602,250 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	92,224,990 - 92,599,999 (+)	NCBI		MGSCv36	mm8
Celera	15	94,541,922 - 94,921,118 (+)	NCBI		Celera
Cytogenetic Map	15	E3	NCBI
cM Map	15	46.53	NCBI

Pdzrn4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	868,626 - 1,005,028 (+)	Ensembl
ChiLan1.0	NW_004955500	638,027 - 1,007,585 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDZRN4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	52,565,942 - 52,952,417 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	52,562,703 - 52,949,173 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	47,123,233 - 47,509,658 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	47,988,518 - 48,373,815 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

PDZRN4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	12,219,332 - 12,361,282 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	12,219,673 - 12,350,691 (-)	Ensembl			canFam3	CanFam3.1
ROS_Cfam_1.0	27	12,416,999 - 12,768,975 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	12,415,435 - 12,635,992 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	12,233,095 - 12,584,445 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	12,265,050 - 12,616,991 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	33,977,613 - 34,329,732 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pdzrn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	72,752,985 - 73,104,853 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	275,680 - 412,061 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	60,003 - 412,087 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDZRN4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	72,574,302 - 72,940,818 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	72,574,370 - 72,940,883 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	75,516,590 - 75,875,425 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDZRN4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	37,432,962 - 37,831,994 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	37,695,495 - 37,832,517 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	208,906,100 - 209,307,969 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pdzrn4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624917	1,086,277 - 1,241,743 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624917	852,264 - 1,241,671 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pdzrn4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	265,407,971 - 265,753,222 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pdzrn4
1216 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	94
Count of miRNA genes:	67
Interacting mature miRNAs:	82
Transcripts:	ENSRNOT00000038686
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	116269196	132020414	Rat
1582240	Sffal1	Serum free fatty acids level QTL 1	3.4	0.0021	blood free fatty acid amount (VT:0001553)	serum free fatty acids level (CMO:0000547)	7	118556868	125929417	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat

Markers in Region

D7Rat62

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	125,651,300 - 125,651,528 (+)	Marker Load Pipeline
mRatBN7.2	7	123,771,817 - 123,772,045 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	133,810,544 - 133,810,771	NCBI	Rnor6.0
Rnor_5.0	7	133,493,805 - 133,494,032	UniSTS	Rnor5.0
RGSC_v3.4	7	131,066,711 - 131,067,094	RGD	RGSC3.4
RGSC_v3.4	7	131,066,774 - 131,067,001	UniSTS	RGSC3.4
Celera	7	120,174,022 - 120,174,249	UniSTS
RGSC_v3.1	7	131,143,211 - 131,143,438	RGD
RH 3.4 Map	7	1014.3	UniSTS
RH 3.4 Map	7	1014.3	RGD
RH 2.0 Map	7	732.2	RGD
SHRSP x BN Map	7	75.96	RGD
Cytogenetic Map	7	q35	UniSTS

D7Rat196

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	123,929,322 - 123,929,461 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	133,968,084 - 133,968,222	NCBI	Rnor6.0
Rnor_5.0	7	133,651,380 - 133,651,518	UniSTS	Rnor5.0
RGSC_v3.4	7	131,229,161 - 131,229,300	RGD	RGSC3.4
RGSC_v3.4	7	131,229,162 - 131,229,300	UniSTS	RGSC3.4
Celera	7	120,330,789 - 120,330,927	UniSTS
RGSC_v3.1	7	131,305,598 - 131,305,737	RGD
SHRSP x BN Map	7	75.9899	RGD
SHRSP x BN Map	7	75.9899	UniSTS
Cytogenetic Map	7	q35	UniSTS

D15Roc10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	123,841,890 - 123,842,130 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	133,881,227 - 133,881,466	NCBI	Rnor6.0
Rnor_5.0	7	133,564,370 - 133,564,609	UniSTS	Rnor5.0
RGSC_v3.4	7	131,140,712 - 131,140,951	UniSTS	RGSC3.4
Celera	7	120,243,662 - 120,243,901	UniSTS
Cytogenetic Map	7	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	11	42	154	62	61	30	64	30	6	252	138	11	129	65	92	31	18	18

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038686 ⟹ ENSRNOP00000037998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	125,696,448 - 125,844,965 (+)	Ensembl
mRatBN7.2 Ensembl	7	123,816,961 - 123,965,491 (+)	Ensembl
Rnor_6.0 Ensembl	7	133,856,101 - 134,004,250 (+)	Ensembl

RefSeq Acc Id:

NM_001108107 ⟹ NP_001101577

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	125,696,448 - 125,844,965 (+)	NCBI
mRatBN7.2	7	123,816,961 - 123,965,491 (+)	NCBI
Rnor_6.0	7	133,856,101 - 134,004,250 (+)	NCBI
Rnor_5.0	7	133,539,221 - 133,687,546 (+)	NCBI
RGSC_v3.4	7	131,114,108 - 131,265,328 (+)	RGD
Celera	7	120,218,741 - 120,366,960 (+)	RGD

Sequence:

show sequence

AGGGGGAGTGTTGCCATGAACTGACTGGAAACTCTGTGTGTATCGTTGAGTGCAAGATACTTCG
GAACGCGGAGAGCATGCACCCTGGCTTCTGCTCTCCGCTACCAGCGGTGTGTCTGTTTCTGGAT
CCAAGTGACTGATGACAAACAGTCCTCAAGTCTGGAGGGAGATTCCCTTTCAGCTCACTTGCCT
TTCAGTTCTGGGGAAACTAGAAGATTTGTGCTCTCTCTCTGCTTCCTAGAATGGGCTGCAACTT
GTGCACTTTTCAGAAAAGAGAGGAACACTACAAACTGCTGTACGAAGTTTCCCAGGTCAATGGC
AAGGATCTCTCGAAGGCCACCCATGAAGAGGCAGTGGAAGCTTTCCGAACCGCCAAGGAGCCCA
TAGTGGTACAGGTGTTAAGGCGGACTCCCCTCAGCCGACCACCATACGGCATGGCCCCGGAAGT
ACAGCTCATGAATGCCAGCACACAGACAGACATCACTTTTGAACACATTATGGCCCTGGCAAAG
CTTCGACCACTCACCCCTCCGGTGCCAGACACCTGTCCGTTTTTGCTTTCAGACAGCTGTCATT
CCCTGCATCCGATGGAGCGTGCATTTTATGAAGACCATGAGTACGTTTCCAGCTTGCCCGCTGA
TGCAGACAGAGCAGAAGACTTTGAATACGAGGAAGTCGAGTTGTGTCGTGTTAGCAGTCAAGAG
AAGCTGGGCCTGACAGTCTGCTACCGAACCGATGATGAAGAAGACACAGGCATTTATGTCAGCG
AGGTTGACCCAAATAGCATTGCTGCCAAGGATGGTCGCATTCGAGAAGGGGATCGTATTTTACA
AATAAACGGGGAAGACATCCAGAACCGGGAAGAGGCCGTGGCTCTGCTCTCGAGTGATGAGTGT
AAGAGAATTGTGCTGCTCATCGCCAGGCCCGATTTGCAGCTGGATGAAGGCTGGCTGGAAGATG
AAAGGAACGAATTCTTAGAGGAGTTAAACTCAGAGATGCTGGAGGAAGAGCGTAATGAAGGAGC
GCAGTGCACAGCCAATGAGCTGCAGCAGCCAAAAAAGCAGGAGGAAGAAGAAGGCACAACAGAC
ACGGCCACATCCTCGTCCAACAACCAGGAGAAGGACAGTGGCGTGGGGCGCACAGATGAGAGCT
TGCGAAATGATGAGAGCTCAGAGCAGGAGAATGTGGTCGAGGAGCCCCACAGCACAGCACTGAA
GAGCAAGAGAGAGCTGGGGCAGAGCCAAGACACCCTAGGAAGCATTGAGCTTCAGTGCAACCAG
AGCTGCGCTGGGGGTGAGTGTTTGGACTCCGACTGTGCCAGCAACCAGGAGGTGTGTGAAGGAT
TCCAGCAGCTATTGGAGCTTAAGATCCGAAACCATGGAGATTATGACCTGTACTACTCAAGCAG
TACGCTCGAATGCAATCAAGGGGAGCAGGACGGGGTGGAGCATGAACTGAAGCTGTTAAATGAG
GAGCTACGAAACATTGAGCTGGAGTGTCAGAATATCATGCAGGCCCACAGGCTCCAGAAAGTGA
CGGACCAATACGGAGACATCTGGGCATTGCATGATGGAGGATTCCGAAATTACAACACCAGCCT
AGATATGCAAAGAGGGAAACTGGACGACATCATAGAGCATCCGGAAAAGTCAGACAAGGACAGC
TCAAGTGCATACAATACAGCTGAGAGCTGCAGAAGCACCCCACTGACTGTAGACAGGTCCCCGG
ACAGTTCCCTTCCAAGAATGATCAACCTCACCAATAAGAAAAATCTGAGGAGCATGATGACAGC
CCATCAGTCCCCTTCCAGACCGAGCACCAGGGAATACACCGCTACCAAAGTCAAAACCACCCAT
GAAGGTTGCAGCGTCGAAAGCCTGGAGAAGAGTCTAGAAAACAGCCAGCTTCTGGATCAGGAGC
ACACAGTCAGTGAGCATACTCCATACCTCTCTCCTTACCACAGCTCCTCCTACAGATATGCCAA
CATTCCGGCGCATGCCCGGCACTATCAAAGCTACATGCAGCTAATTCAACAGAAATCTGCCGTA
GAGTATGCCCAGAGTCAGCTCAGCCTGGTGAGCATGTGCAAGGAATCGCCGAGGGGCTCAGAGC
CCAAGATGGAATGGAAGGTAAAAATTAGAAGTGATGGGACCCGGTACATAACCAAGAGGCCAGT
GCGAGACCGACTTCTGAAGGAACGTGCCTTAAAGATCAAGGAGGAGCGGAGCGGCATGACCACA
GATGACGACACCATGAGTGAGATGAAAATGGGGCGCTACTGGAGCAAGGAGGAGAGAAAGCAAC
ACCTGGTCCGGGCCAAGGAGCAAAGGCGGCGCCGGGAGTTCATGATGCGGAGTCGGCTGGAGAG
CCTCAAGGAGAGCCCACAGAGCAGCGGCGAGGGCAAGAAGGAGCTGAGCATCATTGAACTGAGC
CACAAGAAGATGATGAAGAAAAGAAACAAGAAAATTTTGGATAACTGGATGACAATCCAAGAAC
TGATGACCCATGGGGCCAAATCCCCGGATGGCACAAGGGTCCACAATGCCTTTCTGTCAGTGAC
CACCGTATGACCAGACACATGGGGACAACTGGCTTAGAGAGCATGCTACCAGTTTCGGTAGAGT
ATCATTGCCTCGTTCAATGTGGCATTTTTATATATATTTTGTGACTTTACAGTTTAAATTTTTT
GTAAGCAAAAATACCTGGTACTTTTTAATTTGTTTTTCATATGCTGGTACCTTCTTTGGCTAAT
ATCTTTCCTTAACTTGTGATATATTCATAGCACACATTTATAGAAAAAAAATAAAACGATGAAA
AAACAAAAGGAAAGAAAAAAAGATGAACAAAAATACTAAGGACCTAATTAATTTCCTATTTTAA
TGTATCTATTGTAAGTTTTAAAAAAGTCTGGATTTATTTCTCTAATTTTCTTATTTCCTATTTT
AATAATTCAATGCCAAAACATGTCTATGCTTACCTCCTGGCATAGTGTATGCTAAATCAGATCT
GCTAATAAACTACATGCCGTATCTTGTCTTATACATGAAGTAGCACCTCTTTCAACATCCTTCT
GTACATTTAAACACATAAATGGCAATCGTCTTTGTCTCAGTAAAGTGTGGGTGGACAATCTTCC
CGTGATATGTAGTGACACTGGTCATGTAGCTAGATAATTGTGGTAATTTGTGACAATAAAAAAA
TAATAAATTATTGATTATCCTAAGAAAAGTTAACCAAGGACTGTTATTTTCTTTGCCCACGGTG
GTTGACATGTTTGGTTGTATGTATACGATTAGAAGACTCTTGATTGTGAATTACAAACTGTGCA
GCTTTTCTATCACCTTTTCTCTTTCAATAAAGTTGTTTTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101577	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL76614	(Get FASTA)	NCBI Sequence Viewer
	EDL76615	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037998
	ENSRNOP00000037998.5

RefSeq Acc Id:

NP_001101577 ⟸ NM_001108107

- UniProtKB:

D3ZNV5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGCNLCTFQKREEHYKLLYEVSQVNGKDLSKATHEEAVEAFRTAKEPIVVQVLRRTPLSRPPYG
MAPEVQLMNASTQTDITFEHIMALAKLRPLTPPVPDTCPFLLSDSCHSLHPMERAFYEDHEYVS
SLPADADRAEDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREG
DRILQINGEDIQNREEAVALLSSDECKRIVLLIARPDLQLDEGWLEDERNEFLEELNSEMLEEE
RNEGAQCTANELQQPKKQEEEEGTTDTATSSSNNQEKDSGVGRTDESLRNDESSEQENVVEEPH
STALKSKRELGQSQDTLGSIELQCNQSCAGGECLDSDCASNQEVCEGFQQLLELKIRNHGDYDL
YYSSSTLECNQGEQDGVEHELKLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWALHDGGFRN
YNTSLDMQRGKLDDIIEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRMINLTNKKNLR
SMMTAHQSPSRPSTREYTATKVKTTHEGCSVESLEKSLENSQLLDQEHTVSEHTPYLSPYHSSS
YRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESPRGSEPKMEWKVKIRSDGTRYI
TKRPVRDRLLKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMR
SRLESLKESPQSSGEGKKELSIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNA
FLSVTTV

hide sequence

Ensembl Acc Id:

ENSRNOP00000037998 ⟸ ENSRNOT00000038686

Protein Domains

PDZ

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZNV5-F1-model_v2	AlphaFold	D3ZNV5	1-775	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308860	AgrOrtholog
BioCyc Gene	G2FUF-32359	BioCyc
Ensembl Genes	ENSRNOG00000022844	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038686	ENTREZGENE
	ENSRNOT00000038686.7	UniProtKB/TrEMBL
Gene3D-CATH	2.30.42.10	UniProtKB/TrEMBL
	6.20.370.60	UniProtKB/TrEMBL
InterPro	E3_ubiquitin-PDZ_ligase	UniProtKB/TrEMBL
	PDZ/DHR/GLGF	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
KEGG Report	rno:315250	UniProtKB/TrEMBL
NCBI Gene	315250	ENTREZGENE
PANTHER	PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4	UniProtKB/TrEMBL
	PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4	UniProtKB/TrEMBL
Pfam	PDZ	UniProtKB/TrEMBL
PhenoGen	Pdzrn4	PhenoGen
PROSITE	PDZ	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000022844	RatGTEx
SMART	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	PDZ	UniProtKB/TrEMBL
UniProt	D3ZNV5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Pdzrn4	PDZ domain containing RING finger 4	Pdzrn4_predicted	PDZ domain containing RING finger 4 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Pdzrn4_predicted	PDZ domain containing RING finger 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD