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Gene: Reck (reversion-inducing-cysteine-rich protein with kazal motifs) Rattus norvegicus

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Symbol:

Reck

Name:

reversion-inducing-cysteine-rich protein with kazal motifs

RGD ID:

1308845

Description:

Predicted to enable Wnt-protein binding activity; coreceptor activity; and metalloendopeptidase inhibitor activity. Predicted to be involved in several processes, including blood vessel development; negative regulation of extracellular matrix disassembly; and positive regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within embryo implantation and embryonic forelimb morphogenesis. Predicted to be located in side of membrane. Predicted to be part of Wnt signalosome. Predicted to be active in plasma membrane. Orthologous to human RECK (reversion inducing cysteine rich protein with kazal motifs); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313488; reversion-inducing cysteine-rich protein with Kazal motifs

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	62,898,717 - 62,965,274 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	62,898,668 - 62,965,270 (+)	Ensembl				GRCr8
mRatBN7.2	5	58,102,961 - 58,169,516 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	58,102,981 - 58,169,502 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	60,083,588 - 60,149,992 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	61,902,399 - 61,968,803 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	61,873,115 - 61,939,270 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	59,348,568 - 59,415,169 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	59,348,639 - 59,415,135 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	63,871,829 - 63,938,407 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	60,341,438 - 60,407,710 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	56,682,966 - 56,749,232 (+)	NCBI		Celera
RGSC_v3.1	5	60,387,714 - 60,408,110 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colonic Neoplasms (ISO)

Experimental Liver Cirrhosis (ISO)

glioblastoma (ISO)

lung non-small cell carcinoma (ISO)

Neoplasm Invasiveness (ISO)

Neoplasm Metastasis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-pilocarpine (EXP)

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methoxyethanol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cumene (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (ISO)

dioxygen (ISO)

diuron (EXP)

dorsomorphin (ISO)

elemental selenium (ISO)

ellagic acid (ISO)

emetine (ISO)

entinostat (ISO)

eugenol (EXP)

fenvalerate (EXP)

fluoranthene (ISO)

folic acid (ISO)

fulvestrant (ISO)

hydrogen peroxide (ISO)

hydroquinone (ISO)

indometacin (ISO)

irinotecan (ISO)

lithium chloride (EXP)

methimazole (EXP)

N-methyl-N'-nitro-N-nitrosoguanidine (EXP)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

nickel sulfate (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

progesterone (ISO)

quercetin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP,ISO)

solasodine (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tetrachloromethane (ISO)

theophylline (ISO)

titanium dioxide (ISO)

tomatidine (ISO)

topotecan (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

Ursonic acid (ISO)

valproic acid (ISO)

zinc dichloride (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood vessel maturation (IBA,ISO)

canonical Wnt signaling pathway (IEA,ISO)

embryo implantation (ISO)

embryonic forelimb morphogenesis (ISO)

extracellular matrix organization (IBA,ISO)

negative regulation of cell migration (IEA,ISO)

negative regulation of extracellular matrix disassembly (IEA,ISO)

positive regulation of canonical Wnt signaling pathway (IEA,ISO)

regulation of angiogenesis (IEA,ISO)

regulation of canonical Wnt signaling pathway (IBA)

regulation of establishment of blood-brain barrier (IEA,ISO)

regulation of extracellular matrix organization (IEA,ISO)

sprouting angiogenesis (IBA)

Wnt signaling pathway (IEA)

Cellular Component

plasma membrane (IBA,IEA,ISO)

side of membrane (IEA)

Wnt signalosome (IEA,ISO)

Molecular Function

coreceptor activity (IEA,ISO)

endopeptidase inhibitor activity (IBA,IEA,ISO)

metalloendopeptidase inhibitor activity (IEA,ISO)

peptidase inhibitor activity (IEA)

protein binding (ISO)

serine-type endopeptidase inhibitor activity (IEA)

Wnt-protein binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9789069	PMID:11747814	PMID:17987394	PMID:18194466	PMID:18300271	PMID:18556655	PMID:18591254	PMID:19838811	PMID:20225208	PMID:23213437	PMID:24812324	PMID:28803732
PMID:30026314	PMID:30424792	PMID:31493243	PMID:32403397	PMID:38686051

Genomics

Comparative Map Data

Reck
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	62,898,717 - 62,965,274 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	62,898,668 - 62,965,270 (+)	Ensembl				GRCr8
mRatBN7.2	5	58,102,961 - 58,169,516 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	58,102,981 - 58,169,502 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	60,083,588 - 60,149,992 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	61,902,399 - 61,968,803 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	61,873,115 - 61,939,270 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	59,348,568 - 59,415,169 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	59,348,639 - 59,415,135 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	63,871,829 - 63,938,407 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	60,341,438 - 60,407,710 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	56,682,966 - 56,749,232 (+)	NCBI		Celera
RGSC_v3.1	5	60,387,714 - 60,408,110 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

RECK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	36,036,913 - 36,124,455 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	36,036,905 - 36,124,455 (+)	Ensembl			hg38	GRCh38
GRCh37	9	36,036,910 - 36,124,452 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	36,026,906 - 36,114,448 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	36,026,915 - 36,114,448	NCBI
Celera	9	35,970,460 - 36,058,013 (+)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	35,990,948 - 36,078,557 (+)	NCBI		HuRef
CHM1_1	9	36,037,355 - 36,124,852 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	36,058,906 - 36,146,459 (+)	NCBI		T2T-CHM13v2.0

Reck
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	43,875,521 - 43,944,806 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	43,875,530 - 43,944,806 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	43,875,521 - 43,944,806 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	43,875,530 - 43,944,806 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	43,888,402 - 43,957,678 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	43,896,700 - 43,965,620 (+)	NCBI		MGSCv36	mm8
MGSCv36	4	42,710,564 - 42,778,727 (+)	NCBI		MGSCv36	mm8
Celera	4	43,902,817 - 43,958,027 (+)	NCBI		Celera
Celera	4	41,986,209 - 41,997,348 (+)	NCBI		Celera
Cytogenetic Map	4	B1	NCBI
cM Map	4	23.05	NCBI

Reck
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	223,683 - 287,089 (-)	Ensembl
ChiLan1.0	NW_004955472	222,261 - 276,869 (-)	NCBI	ChiLan1.0	ChiLan1.0

RECK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	88,465,165 - 88,552,758 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	88,471,105 - 88,559,789 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	35,886,741 - 35,974,133 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	36,703,607 - 36,775,516 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	36,699,631 - 36,774,116 (+)	Ensembl			panPan2	panpan1.1

RECK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	52,519,303 - 52,607,753 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	52,519,317 - 52,607,217 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	51,109,989 - 51,185,477 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	53,625,516 - 53,714,665 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	53,625,498 - 53,790,061 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	52,128,385 - 52,204,061 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	52,150,596 - 52,226,091 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	52,852,123 - 52,927,620 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Reck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	167,474,080 - 167,552,123 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	4,021,660 - 4,099,705 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	4,021,666 - 4,099,703 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RECK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	236,821,414 - 236,898,276 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	236,821,243 - 236,898,280 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	264,672,781 - 264,733,611 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RECK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	44,431,807 - 44,517,893 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	44,431,615 - 44,517,810 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	41,521,945 - 41,609,100 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Reck
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	4,603,955 - 4,713,652 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624868	4,604,157 - 4,713,838 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Reck
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	2,578,732 - 2,644,247 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Reck
329 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	97
Count of miRNA genes:	85
Interacting mature miRNAs:	92
Transcripts:	ENSRNOT00000060264
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	52665372	94894052	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	48523123	91770353	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	60511627	105511627	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	56546393	101546393	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	23671493	68671493	Rat

Markers in Region

D5Got225

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	62,929,143 - 62,929,329 (+)	Marker Load Pipeline
mRatBN7.2	5	58,133,387 - 58,133,573 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	59,379,041 - 59,379,226	NCBI	Rnor6.0
Rnor_5.0	5	63,902,279 - 63,902,464	UniSTS	Rnor5.0
RGSC_v3.4	5	60,371,806 - 60,371,991	UniSTS	RGSC3.4
Celera	5	56,713,279 - 56,713,472	UniSTS
Cytogenetic Map	5	q22	UniSTS

RH130414

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	58,169,197 - 58,169,377 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	59,414,851 - 59,415,030	NCBI	Rnor6.0
Rnor_5.0	5	63,938,089 - 63,938,268	UniSTS	Rnor5.0
RGSC_v3.4	5	60,407,616 - 60,407,795	UniSTS	RGSC3.4
Celera	5	56,749,138 - 56,749,317	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	84	59	6	348	184	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001415923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000060264 ⟹ ENSRNOP00000057015

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	62,898,674 - 62,965,270 (+)	Ensembl
mRatBN7.2 Ensembl	5	58,102,987 - 58,169,292 (+)	Ensembl
Rnor_6.0 Ensembl	5	59,348,640 - 59,414,945 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084031 ⟹ ENSRNOP00000070900

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	62,898,674 - 62,965,270 (+)	Ensembl
mRatBN7.2 Ensembl	5	58,102,981 - 58,169,502 (+)	Ensembl
Rnor_6.0 Ensembl	5	59,348,639 - 59,415,135 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106073 ⟹ ENSRNOP00000079723

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	62,898,668 - 62,965,270 (+)	Ensembl
mRatBN7.2 Ensembl	5	58,122,831 - 58,169,502 (+)	Ensembl

RefSeq Acc Id:

NM_001415923 ⟹ NP_001402852

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	62,898,717 - 62,965,274 (+)	NCBI
mRatBN7.2	5	58,102,961 - 58,169,516 (+)	NCBI

RefSeq Acc Id:

XM_006238069 ⟹ XP_006238131

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	62,923,189 - 62,965,271 (+)	NCBI
mRatBN7.2	5	58,124,285 - 58,169,513 (+)	NCBI
Rnor_6.0	5	59,372,058 - 59,415,169 (+)	NCBI
Rnor_5.0	5	63,871,829 - 63,938,407 (+)	NCBI

Sequence:

show sequence

ATCTTATTTAACAAATTTAGATATAGACTATTCTAGTCTTCTCAGAACTGACAAAATAACTTAA
ATTTTAAAAATTAATTCATTTTTAAACAAATTGTGTTCTAACTTAGCAGAAAATTTAGCCCTAA
TAGAAATGTCACTTTCTCTGAAGTGTTTTGACTTTGAGATTTGTAGACATTAAATATTGATTTT
AAAGAAATACTTTAAATCTCTCATTCTAGCATTTCATCTATTATATTTTTATAGCAAAGCCACT
GGTTGATTTAAGATTCTGAACTTGTTTTTTATAAGTTCTGTATCCTCTATAGCCCCTGTCCTAC
CTCTAGACCCATCTTTATGTCCGTTGTTTTATAAGCTGCCTATATCAAGAAATAAACTAAGCAA
GTCAGACGGCTAAAATGAGCACTCATGCTTCAGCACCTCGCATTTGGGGAACCCTCGTCTCCGG
GATGGGTTTCCAGCACCGTGCTCCCTAGTATGGAGATAAGAGAGTGAAAGTAGAGGAGATAGTT
CACCTTGTACAAATGTACAAAACTCCTTTAGGTGTCTGTTTTCTAGAACCCCTTGAAGTGTGAC
ACTTGTGTTACTCTCAGAGTTAAGGTCATGGAGTTGGGAGACTTAAATGCATAACAATGAGGAC
CCTATTAACAGTCTGTATTTGGGAGAAACAGAGTCATTCCCGCTGCTTCTATGCCATACTTCCG
ATTAATTGGTTTTTCTTTTCTCAAAGTCTATAATTATATTTCTTCATTAACATTTTTAGACTGG
AGAGTCTTATTTATCCTTTGTCCCTTTGTTCTGTTGGCTAAGTTACATCTGGTCTCTGAAGACA
AGTTTCCAAGTCAACATCAACCTCCCTCTGATCCTCCTGGAAAGAGCCTGTTGTCCAGAAGGAG
GGGAGCTTTTAATGTTTTTTCTTACCTCTACCTTTGAAATGACCATTTTGGGTTTCTCTTGAAC
AAAGTGCCTAACTGTGATAATTCCTTCTTTTCTTCCACATGATGTCTGACACTGTCCATCTCCT
GTAGCCTGTCCTCCATTACTTTAGTGTGCTTCCTTCTCTTGTTTGGATTTCTGCATTGCCCTAG
GAAGTCTGCAGTGTGTGTTGATGAAGGACGAGACAGGAAAGAACGCTCTTTTCAGTTGCATTAG
CAGAAATGAAATGGGCTCGGTGTGCTGCAGTTACGCGGGGCATCACACCAACTGCCGAGAATTC
TGTCAAGCCATTTTTCGAACAGACTCCTCTCCTGGACCATCTCAGATCAAAGCAGTGGAAAATT
ATTGTGCGTCTATTAGTCCACAGTTGATACACTGTGTGAACAATTACACCCAGTCGTATCCAAT
GAGAAACCCAACTGACAGTTTGTACTGCTGTGACAGAGCTGAAGAGCATGCTTGCCAGAGCGCC
TGCAGGAGGATTCTAACGTCTAAGAAGACAGAAATGGAGATTGTGGACGGCCTCATTGAGGGTT
GCAAGACCCAGCCCTTGCCTCAAGATCCTCTTTGGCAGTGTTTTCTCGAAAGCTCACAGTCAGT
TCACCCTGGAGTCACCGTGCACCCTCCTCCCTCAACCGGCCTTGATGGGGCCAAATTGCATTGT
TGCTCTAAAGCAAACACCTCAGTGTGTAGGGAATTGTGCACGAAACTCTACAGCATGAGCTGGG
GAAACACACAGAGCTGGCAGGAGTTTGACCGCATCTGTGAATATAACCCCGGGGAAGTGTCCAT
GCTGGCCTGTCTGGCTGATGTCCGGGAGCCTTGCCAGTTGGGTTGTACAAACCTTACTTACTGT
ACAAACTTTAACAACAGGCCAACAGAACTTTTCAGGAGCTGCACGGCGCAGTCTGACCAGGGCG
CCATGAGTGACATGAGGCTGTGGGAGAAGGGCAGCATAAAGATGCCCTTCATCAGCATCCCCGT
CCTGGACATTAGAACCTGCCAGCCAGACCTGTGGAAGGCCGTCGCCTGCTCCCTGCAGATCAAG
CCGTGCCACAGGAAGTCCCGAGGGAGCATCATCTGCAAATCAGATTGTGTAGAGATTCTCAAGA
AATGTGGAGACCAGAATAAATTCCCTGAAGCCCACACAGCTGAAAGTATCTGTGAGTTCCTGTC
CCCTGCAGATGATGTGGAGAACTGTATACCTCTGGACACATACCTCAGGCCAAGTGCTTTAGGC
AACATCATAGAGGAAGTGACTCATCCCTGTAATCCAAATCCTTGCCCAGCCAATGAGCTCTGTG
AAGTAAACCGAAAGGGGTGTCCGTCTGGAGATCCCTGCCTTCCGTACTCCTGTGTTCAAGGCTG
CAAATTGGGAGAAGCGTCTGACTTCATTGTCCGCCAAGGGGCACTGATCCAGGTGCCATCCTCT
GCAGGGGAAGTTGGTTGTTACAAAATCTGTTCCTGTGGACAAAGTGGCCTCTTGGAAAACTGCA
TGGAAATGCACTGTATTGACCTCCAGAAGTCTTGCATTGTTGGAGGGAAAAGAAAGAGTCATGG
AACATCCTTTACCATCGACTGCAATGTCTGTTCTTGTTTTGCCGGCAATTTAGTGTGTTCCACC
CGTCTGTGCCTCAGTGAGCACAGTTCAGACGATGACCGCCGCGCCTTCACAGGTCTGCCCTGTA
ACTGCGCAGATCAGTTTGTCCCAGTGTGTGCACAGAATGGACGCACTTACCCCAGTGCCTGCAT
CGCTCGCTGTGTGGGTCTCCAGGACCATCAGTTTGAGTTTGGACCTTGTATCTCCAAGGATCCC
TGTAATCCTAACCTCTGCCCCAAAAGCCAAAGATGTGTGCCCAAACCGCAAGTCTGCCTGACTA
CTTTTGATAAATTTGGATGTAGCCAGTATGAGTGCGTGCCCAGACAGCTCACGTGTGACCAGGC
CCGAGATCCTGTGTGTGACACAGATCATGTGGAGCACAGCAACCTCTGCACTTTGTACCAAAGA
GGAAAAAGCCTGTCCTACAGAGGCCCGTGCCAGCCTTTCTGCAGAACCACGGAGCCTGTTTGTG
GGCACAATGGTGAGACGTACAGCAGTGTGTGCGCTGCCTACTCGGATCGTGTGGCAGTGGATTA
CTATGGGCGCTGCCAGGCTGTCGGGGTCCTCTCGGAACACAGTGCTGTGACCGAGTGTGCTGCT
GTGAAGTGTCCTTCCCTCTCAGCTATAGGTTGCAAACCCATCATTCCACCAGGGGCTTGCTGCC
CATTATGTGCTGGGATGCTACGGGTTTTATTTGACAAAGAAAAGTTGGACACAATTGCTAAGGT
GACAAACAAGAAGCCGATAACCGTTCTGGAGATTCTCCAGAAGATCCGCATGCACGTGTCTGTG
CCGCAGTGCGATGTGTTCGGGTACTTGAGCATCGAGTCAGAGATTGTGATCCTGATTATTCCTG
TGGACCATTATCCCAAAGCTTTGCAGATTGAGGCCTGCAATAAGGAAGCAGAGAAAATCGAGTC
CCTCATCAACTCCGACAGCCCCACGCTGGCATCCCACGTCCCGCTGTCCGCCCTCATCATCTCC
CAGGTGCAGGTGTCCAGCAGTCTCCCGTCATCCGCTGTTGTGGGCAGGCTTCCTCCCGTCCACT
CGTTGCCCCTCTTCCTCAGCCTGGGCCTCACTGTGCACCTGCTCCAGACCTGTCCCTGACCACC
CTGCAAAGCCTTCCTCCACCCAGCCGTCCCAGCCTGTGAAAGACATTCAGGACTGCAAGACGGT
GACCAAGCAAAAACACGTGCGGGTCACCTCTTAGCACCACACAGTATTTTTTAATCTGCCAATA
TTAGGGGTTTTGCCTTGATTTTTAAATGGTAAACTAGACTGCCCCAATGTAACAGAAGACAACG
ACGCTCACTGGTGGATCACTGGGCAGTTTACGATTGCTCAGTAGAGGACTCCCCTGGCCCAAAG
CCAGCTTGCCATCGCTGATCAATACATGGCCACTTACAGGAGGAGGCCCTGCTTTGTGCCCTAG
TCCCCTCAGAGTCCCCGTGAGTGCTGAGGCTGCCGTGTGCTTGTTTCTGTCCGGAAGCTGAGGG
CTCAGGAGAAGCCACAGCCGTGACGGAGTGGGAGGAGAGAAACACGGTTGAAGTATCACTAGTT
CATCAGGGCTGACTCCGTAGAAATGTAAGGCAGGCTCTAGTGTGTCACAAAAGCACTCATGTGC
CTGTCTCACAACTGGCCCTCTCAGCAGCTGCCCTTCTGTGCCTGTGATGGGAGTGGCCCCAAGC
GAGCGGCCAAGCACCTGTATCATGCAGCCTTGGATTAGCAGAGACACTCGGCAGTACTCCCACG
TTCACAGGGTCAGAGGTCAGGCTTTAAACCACTTGCTGCTACTATGTAATTGCCAAAAGTAAGG
TAACTAGTCGTCCGTGTAGGTAGTACATGATAATTTTATTCTGAAGGTGAATAGCCATATGTGT
AAATGACAATCATGTGTTAGCCATGCTTCCGTTCATGAAGACACATCTGCTCTTATAATGTGCG
CAGTGTGGATATGTGTGTGTCTGACTTTCCTTTTATATAGAACTATAAAGAATGTGGTTTATAT
ATTTAAAGTGTCAGGCTAAATATTAGAATGTTTGCATGTTATCTAAGAAATTGAATACTTTGAA
TGTTTTACAGTTTGAAATAAGCTATTAATGTAATACTTCCTGTTTGTATGCACCTGAACTTAGA
TTTTATATGAAGTATTTTTCAGTGTTGTATGTACCCTCTGAGATACTCAATATGCTTGTCATAC
CAAATGTTGTCGAGCAGTGGGCACTTAGTGCTTTCGGAGGAGCTCAGTGCTGATGTTCTGTACC
TCTGGCAGTTGCCTGTTTCTGTCTAAGTGTCCTCAACATACTAGACTTTATTATATGTATATTC
CAAATATAGTATTACAGAATATACTATATATATTCTATATATACAGCAATATACTAGAAAGCTT
TTCTATTTTAATAAAAGTAATTTTATATGATCA

hide sequence

RefSeq Acc Id:

XM_063287725 ⟹ XP_063143795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	62,918,247 - 62,965,271 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001402852	(Get FASTA)	NCBI Sequence Viewer
	XP_006238131	(Get FASTA)	NCBI Sequence Viewer
	XP_063143795	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98778	(Get FASTA)	NCBI Sequence Viewer
	EDL98779	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000057015.3
	ENSRNOP00000070900
	ENSRNOP00000070900.1
	ENSRNOP00000079723.2

RefSeq Acc Id:	XP_006238131 ⟸ XM_006238069
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZRL0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKDETGKNALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISP QLIHCVNNYTQSYPMRNPTDSLYCCDRAEEHACQSACRRILTSKKTEMEIVDGLIEGCKTQPLP QDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTSVCRELCTKLYSMSWGNTQSWQ EFDRICEYNPGEVSMLACLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMRL WEKGSIKMPFISIPVLDIRTCQPDLWKAVACSLQIKPCHRKSRGSIICKSDCVEILKKCGDQNK FPEAHTAESICEFLSPADDVENCIPLDTYLRPSALGNIIEEVTHPCNPNPCPANELCEVNRKGC PSGDPCLPYSCVQGCKLGEASDFIVRQGALIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCID LQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRAFTGLPCNCADQFV PVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKDPCNPNLCPKSQRCVPKPQVCLTTFDKFGC SQYECVPRQLTCDQARDPVCDTDHVEHSNLCTLYQRGKSLSYRGPCQPFCRTTEPVCGHNGETY SSVCAAYSDRVAVDYYGRCQAVGVLSEHSAVTECAAVKCPSLSAIGCKPIIPPGACCPLCAGML RVLFDKEKLDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYLSIESEIVILIIPVDHYPKA LQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGRLPPVHSLPLFLS LGLTVHLLQTCP hide sequence

Ensembl Acc Id:

ENSRNOP00000057015 ⟸ ENSRNOT00000060264

Ensembl Acc Id:

ENSRNOP00000070900 ⟸ ENSRNOT00000084031

Ensembl Acc Id:

ENSRNOP00000079723 ⟸ ENSRNOT00000106073

RefSeq Acc Id:	NP_001402852 ⟸ NM_001415923
- Peptide Label:	precursor
- UniProtKB:	A0A0G2JZ40 (UniProtKB/TrEMBL), A6IJ58 (UniProtKB/TrEMBL), A6IJ59 (UniProtKB/TrEMBL), D4ABJ4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063143795 ⟸ XM_063287725
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZRL0 (UniProtKB/TrEMBL)

Protein Domains

Kazal-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JZ40-F1-model_v2	AlphaFold	A0A0G2JZ40	1-972	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693687

Promoter ID:

EPDNEW_R4209

Type:

initiation region

Name:

Reck_1

Description:

reversion-inducing-cysteine-rich protein with kazal motifs

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	59,348,614 - 59,348,674	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308845	AgrOrtholog
BioCyc Gene	G2FUF-41482	BioCyc
Ensembl Genes	ENSRNOG00000014863	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000060264.4	UniProtKB/TrEMBL
	ENSRNOT00000084031	ENTREZGENE
	ENSRNOT00000084031.3	UniProtKB/TrEMBL
	ENSRNOT00000106073.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.60.30	UniProtKB/TrEMBL
InterPro	CC4_RECK	UniProtKB/TrEMBL
	EGF1_RECK	UniProtKB/TrEMBL
	FnI_RECK	UniProtKB/TrEMBL
	FZ_RECK	UniProtKB/TrEMBL
	Kazal_dom_sf	UniProtKB/TrEMBL
	Prot_inh_Kazal	UniProtKB/TrEMBL
	RECK	UniProtKB/TrEMBL
	RECK-like_dom	UniProtKB/TrEMBL
	RECK-like_N	UniProtKB/TrEMBL
NCBI Gene	313488	ENTREZGENE
PANTHER	PTHR13487	UniProtKB/TrEMBL
	REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS	UniProtKB/TrEMBL
Pfam	CC4_RECK	UniProtKB/TrEMBL
	EGF1_RECK	UniProtKB/TrEMBL
	FnI_RECK	UniProtKB/TrEMBL
	FZ_RECK	UniProtKB/TrEMBL
	Kazal_2	UniProtKB/TrEMBL
	RECK-like_dom	UniProtKB/TrEMBL
	RECK-like_N	UniProtKB/TrEMBL
PhenoGen	Reck	PhenoGen
PROSITE	KAZAL	UniProtKB/TrEMBL
	KAZAL_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014863	RatGTEx
SMART	KAZAL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF100895	UniProtKB/TrEMBL
UniProt	A0A0G2JZ40	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZRL0	ENTREZGENE, UniProtKB/TrEMBL
	A6IJ58	ENTREZGENE, UniProtKB/TrEMBL
	A6IJ59	ENTREZGENE, UniProtKB/TrEMBL
	D4ABJ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Reck	reversion-inducing-cysteine-rich protein with kazal motifs	Reck_predicted	reversion-inducing-cysteine-rich protein with kazal motifs (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Reck_predicted	reversion-inducing-cysteine-rich protein with kazal motifs (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD