Zfp772 (zinc finger protein 772) - Rat Genome Database

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Gene: Zfp772 (zinc finger protein 772) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zfp772
Name: zinc finger protein 772
RGD ID: 1308782
Description: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC308318; LOC308318; MGC114396; RGD1308782; similar to Zinc finger protein OZF (POZF-1); uncharacterized protein LOC308318; Zfp978; zinc finger protein 419; zinc finger protein 978
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8175,735,754 - 75,742,480 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl175,735,754 - 75,742,480 (-)EnsemblGRCr8
mRatBN7.2166,702,628 - 66,709,355 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,702,632 - 66,709,355 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx172,054,044 - 72,060,770 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0180,691,072 - 80,697,798 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0173,885,484 - 73,892,221 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,736,905 - 69,743,906 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,736,684 - 69,743,616 (-)Ensemblrn6Rnor6.0
Rnor_5.0171,133,880 - 71,140,547 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4165,100,856 - 65,107,536 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera164,458,029 - 64,464,713 (-)NCBICelera
RGSC_v3.1165,179,290 - 65,185,647 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in Zfp772
3 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:443
Count of miRNA genes:234
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000030259, ENSRNOT00000042086
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
RH133000  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,782,009 - 66,782,203 (+)MAPPERmRatBN7.2
Rnor_6.0169,859,177 - 69,859,370NCBIRnor6.0
Rnor_5.0171,256,097 - 71,256,290UniSTSRnor5.0
RGSC_v3.4165,180,414 - 65,180,607UniSTSRGSC3.4
Celera164,535,771 - 64,535,964UniSTS
RH 3.4 Map1742.6UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 162 91 90 59 86 59 6 349 185 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000030259   ⟹   ENSRNOP00000031196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,735,754 - 75,742,480 (-)Ensembl
mRatBN7.2 Ensembl166,702,632 - 66,709,355 (-)Ensembl
Rnor_6.0 Ensembl169,736,909 - 69,743,616 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079497   ⟹   ENSRNOP00000075325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,735,754 - 75,742,480 (-)Ensembl
mRatBN7.2 Ensembl166,702,635 - 66,709,337 (-)Ensembl
Rnor_6.0 Ensembl169,736,684 - 69,740,201 (-)Ensembl
RefSeq Acc Id: NM_001025677   ⟹   NP_001020848
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,735,754 - 75,742,480 (-)NCBI
mRatBN7.2166,702,628 - 66,709,355 (-)NCBI
Rnor_6.0169,736,905 - 69,743,616 (-)NCBI
Rnor_5.0171,133,880 - 71,140,547 (-)NCBI
RGSC_v3.4165,100,856 - 65,107,536 (-)RGD
Celera164,458,029 - 64,464,713 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399374   ⟹   NP_001386303
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,735,754 - 75,742,480 (-)NCBI
mRatBN7.2166,702,628 - 66,709,355 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020848 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386303 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97363 (Get FASTA)   NCBI Sequence Viewer  
  EDL83200 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000031196
  ENSRNOP00000031196.3
  ENSRNOP00000075325
  ENSRNOP00000075325.2
RefSeq Acc Id: NP_001020848   ⟸   NM_001025677
- Peptide Label: isoform 2
- UniProtKB: Q4V8J3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075325   ⟸   ENSRNOT00000079497
Ensembl Acc Id: ENSRNOP00000031196   ⟸   ENSRNOT00000030259
RefSeq Acc Id: NP_001386303   ⟸   NM_001399374
- Peptide Label: isoform 1
- UniProtKB: A0A0G2KAA5 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KAA5-F1-model_v2 AlphaFold A0A0G2KAA5 1-347 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308782 AgrOrtholog
BioCyc Gene G2FUF-60968 BioCyc
Ensembl Genes ENSRNOG00000015598 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030259 ENTREZGENE
  ENSRNOT00000030259.5 UniProtKB/TrEMBL
  ENSRNOT00000079497 ENTREZGENE
  ENSRNOT00000079497.3 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7442984 IMAGE-MGC_LOAD
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Snail/Krueppel_Znf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:308318 UniProtKB/TrEMBL
MGC_CLONE MGC:114396 IMAGE-MGC_LOAD
NCBI Gene 308318 ENTREZGENE
PANTHER PROTEIN ESCARGOT UniProtKB/TrEMBL
  TRANSCRIPTIONAL REPRESSOR PROTEIN YY UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 143 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp772 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015598 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2KAA5 ENTREZGENE, UniProtKB/TrEMBL
  Q4V8J3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-27 Zfp772  zinc finger protein 772  Zfp978  zinc finger protein 978  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Zfp978  zinc finger protein 978  RGD1308782  similar to Zinc finger protein OZF (POZF-1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308782  similar to Zinc finger protein OZF (POZF-1)  RGD1308782_predicted  similar to Zinc finger protein OZF (POZF-1) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308782_predicted  similar to Zinc finger protein OZF (POZF-1) (predicted)  LOC308318_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC308318_predicted  similar to Zinc finger protein OZF (POZF-1) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL