Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pamr1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PAMR1 mRNA | CTD | PMID:22206623 | Pamr1 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of PAMR1 mRNA | CTD | PMID:25380136 | Pamr1 | Rat | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of PAMR1 mRNA | CTD | PMID:17351261 | Pamr1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of PAMR1 mRNA | CTD | PMID:29097150 | Pamr1 | Rat | 17beta-estradiol | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Estradiol results in increased expression of PAMR1 mRNA | CTD | PMID:19484750 | Pamr1 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Plant Preparations] results in decreased expression of PAMR1 mRNA | CTD | PMID:26945725 | Pamr1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PAMR1 mRNA | CTD | PMID:32109520 | Pamr1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Pamr1 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of PAMR1 mRNA | CTD | PMID:38648751 | Pamr1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Pamr1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of PAMR1 mRNA | CTD | PMID:30951980 | Pamr1 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of PAMR1 mRNA | CTD | PMID:39298647 | Pamr1 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Decitabine affects the expression of PAMR1 mRNA | CTD | PMID:23300844 | Pamr1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PAMR1 mRNA | CTD | PMID:30047161 | Pamr1 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PAMR1 mRNA | CTD | PMID:28959563 | Pamr1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PAMR1 mRNA | CTD | PMID:33354967 | Pamr1 | Rat | all-trans-retinoic acid | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PAMR1 mRNA | CTD | PMID:21934132 | Pamr1 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PAMR1 mRNA | CTD | PMID:30047161 | Pamr1 | Rat | antirheumatic drug | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PAMR1 mRNA | CTD | PMID:24449571 | Pamr1 | Rat | arsane | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PAMR1 more ... | CTD | PMID:32525701 | Pamr1 | Rat | arsenic atom | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PAMR1 more ... | CTD | PMID:32525701 | Pamr1 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | PAMR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of PAMR1 gene | CTD | PMID:25435355 | Pamr1 | Rat | benzo[a]pyrene | increases methylation | ISO | PAMR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PAMR1 3' UTR | CTD | PMID:27901495 | Pamr1 | Rat | benzo[a]pyrene | affects methylation | ISO | PAMR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PAMR1 promoter | CTD | PMID:27901495 | Pamr1 | Rat | benzo[a]pyrene | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PAMR1 mRNA | CTD | PMID:23735875 | Pamr1 | Rat | benzo[b]fluoranthene | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of PAMR1 mRNA | CTD | PMID:26377693 | Pamr1 | Rat | Benzo[ghi]perylene | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | 1,12-benzoperylene results in increased expression of PAMR1 mRNA | CTD | PMID:26377693 | Pamr1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PAMR1 mRNA | CTD | PMID:25181051|PMID:34947998|PMID:41034487 | Pamr1 | Rat | bisphenol A | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PAMR1 mRNA | CTD | PMID:30245210|PMID:30951980 | Pamr1 | Rat | bisphenol A | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PAMR1 mRNA | CTD | PMID:29275510 | Pamr1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PAMR1 mRNA | CTD | PMID:29097150 | Pamr1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PAMR1 gene | CTD | PMID:28505145 | Pamr1 | Rat | bisphenol A | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PAMR1 mRNA | CTD | PMID:25594700 | Pamr1 | Rat | bisphenol F | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Pamr1 | Rat | bisphenol F | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of PAMR1 mRNA | CTD | PMID:30951980 | Pamr1 | Rat | calcitriol | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of PAMR1 mRNA | CTD | PMID:26485663 | Pamr1 | Rat | carbon nanotube | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of PAMR1 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Pamr1 | Rat | cisplatin | affects expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of PAMR1 mRNA | CTD | PMID:23300844 | Pamr1 | Rat | crocidolite asbestos | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of PAMR1 mRNA | CTD | PMID:29279043 | Pamr1 | Rat | cytarabine | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of PAMR1 mRNA | CTD | PMID:21198554 | Pamr1 | Rat | DDT | decreases expression | EXP | | 6480464 | DDT results in decreased expression of PAMR1 mRNA | CTD | PMID:30207508 | Pamr1 | Rat | dexamethasone | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of PAMR1 mRNA | CTD | PMID:25047013 | Pamr1 | Rat | dexamethasone | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Pamr1 | Rat | dibutyl phthalate | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of PAMR1 mRNA | CTD | PMID:21266533 | Pamr1 | Rat | dioxygen | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PAMR1 mRNA | CTD | PMID:30529165 | Pamr1 | Rat | dorsomorphin | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Pamr1 | Rat | doxorubicin | affects expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of PAMR1 mRNA | CTD | PMID:29803840 | Pamr1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PAMR1 mRNA | CTD | PMID:29391264 | Pamr1 | Rat | entinostat | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of PAMR1 mRNA | CTD | PMID:26272509 | Pamr1 | Rat | entinostat | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Pamr1 | Rat | ethanol | affects expression | ISO | Pamr1 (Mus musculus) | 6480464 | Ethanol affects the expression of PAMR1 mRNA | CTD | PMID:30319688 | Pamr1 | Rat | ferric oxide | increases expression | EXP | | 6480464 | ferric oxide analog results in increased expression of PAMR1 mRNA | CTD | PMID:38615722 | Pamr1 | Rat | folic acid | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PAMR1 mRNA | CTD | PMID:22206623 | Pamr1 | Rat | formaldehyde | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of PAMR1 mRNA | CTD | PMID:28937961 | Pamr1 | Rat | fulvestrant | increases methylation | ISO | PAMR1 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of PAMR1 gene | CTD | PMID:31601247 | Pamr1 | Rat | glycidyl methacrylate | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | glycidyl methacrylate results in decreased expression of PAMR1 protein | CTD | PMID:36641056 | Pamr1 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of PAMR1 mRNA | CTD | PMID:21396975 | Pamr1 | Rat | indometacin | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Pamr1 | Rat | inulin | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PAMR1 mRNA | CTD | PMID:36331819 | Pamr1 | Rat | maneb | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PAMR1 mRNA | CTD | PMID:36117858 | Pamr1 | Rat | mercury dibromide | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of PAMR1 mRNA | CTD | PMID:26272509 | Pamr1 | Rat | mercury dibromide | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Pamr1 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PAMR1 mRNA | CTD | PMID:30047161 | Pamr1 | Rat | methylmercury chloride | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PAMR1 mRNA | CTD | PMID:28001369 | Pamr1 | Rat | mifepristone | decreases expression | EXP | | 6480464 | Mifepristone results in decreased expression of PAMR1 mRNA | CTD | PMID:25972201 | Pamr1 | Rat | nickel atom | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of PAMR1 mRNA | CTD | PMID:24768652|PMID:25583101 | Pamr1 | Rat | nickel sulfate | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of PAMR1 mRNA | CTD | PMID:22714537 | Pamr1 | Rat | okadaic acid | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of PAMR1 mRNA | CTD | PMID:38832940 | Pamr1 | Rat | ozone | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Pamr1 | Rat | panobinostat | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Pamr1 | Rat | panobinostat | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of PAMR1 mRNA | CTD | PMID:26272509 | Pamr1 | Rat | paracetamol | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PAMR1 mRNA | CTD | PMID:29067470 | Pamr1 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of PAMR1 mRNA | CTD | PMID:32680482 | Pamr1 | Rat | paraquat | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PAMR1 mRNA | CTD | PMID:36117858 | Pamr1 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of PAMR1 mRNA | CTD | PMID:37995155 | Pamr1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Pamr1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PAMR1 mRNA | CTD | PMID:36331819 | Pamr1 | Rat | phenylmercury acetate | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of PAMR1 mRNA | CTD | PMID:26272509 | Pamr1 | Rat | phenylmercury acetate | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Pamr1 | Rat | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of PAMR1 mRNA | CTD | PMID:30047161 | Pamr1 | Rat | resveratrol | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PAMR1 mRNA | CTD | PMID:23557933 | Pamr1 | Rat | SB 431542 | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Pamr1 | Rat | silicon dioxide | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of PAMR1 mRNA | CTD | PMID:25351596 | Pamr1 | Rat | sodium arsenate | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PAMR1 more ... | CTD | PMID:32525701 | Pamr1 | Rat | sodium arsenite | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PAMR1 mRNA | CTD | PMID:22714537 | Pamr1 | Rat | sodium arsenite | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PAMR1 mRNA | CTD | PMID:37682722 | Pamr1 | Rat | sodium arsenite | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of PAMR1 mRNA | CTD | PMID:36209798 | Pamr1 | Rat | sodium arsenite | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PAMR1 mRNA | CTD | PMID:29301061 | Pamr1 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of PAMR1 mRNA | CTD | PMID:30047161 | Pamr1 | Rat | temozolomide | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PAMR1 mRNA | CTD | PMID:31758290 | Pamr1 | Rat | testosterone | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | Testosterone deficiency results in increased expression of PAMR1 mRNA | CTD | PMID:33848595 | Pamr1 | Rat | titanium dioxide | decreases expression | ISO | Pamr1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PAMR1 mRNA | CTD | PMID:27760801 | Pamr1 | Rat | titanium dioxide | affects expression | ISO | Pamr1 (Mus musculus) | 6480464 | titanium dioxide affects the expression of PAMR1 mRNA | CTD | PMID:23557971 | Pamr1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PAMR1 mRNA | CTD | PMID:33387578 | Pamr1 | Rat | trichostatin A | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of PAMR1 mRNA | CTD | PMID:24935251|PMID:26272509 | Pamr1 | Rat | trichostatin A | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Pamr1 | Rat | triclosan | increases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of PAMR1 mRNA | CTD | PMID:30510588 | Pamr1 | Rat | troglitazone | increases expression | ISO | Pamr1 (Mus musculus) | 6480464 | troglitazone results in increased expression of PAMR1 mRNA | CTD | PMID:28973697 | Pamr1 | Rat | valproic acid | decreases methylation | ISO | PAMR1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PAMR1 gene | CTD | PMID:29154799 | Pamr1 | Rat | valproic acid | affects expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PAMR1 mRNA | CTD | PMID:25979313 | Pamr1 | Rat | valproic acid | decreases expression | ISO | PAMR1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PAMR1 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:28001369 | Pamr1 | Rat | valproic acid | multiple interactions | ISO | PAMR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | |






















