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Gene: Znhit6 (zinc finger, HIT-type containing 6) Rattus norvegicus

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Symbol:

Znhit6

Name:

zinc finger, HIT-type containing 6

RGD ID:

1308723

Description:

Predicted to enable ATPase binding activity; TFIID-class transcription factor complex binding activity; and identical protein binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); protein-containing complex assembly; and snoRNA localization. Predicted to be part of pre-snoRNP complex. Predicted to be active in nucleus. Orthologous to human ZNHIT6 (zinc finger HIT-type containing 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

box C/D snoRNA protein 1; LOC292160; RGD1308723; similar to hypothetical protein FLJ20729; zinc finger, HIT type 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNHIT6 (zinc finger HIT-type containing 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Znhit6 (zinc finger, HIT type 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znhit6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNHIT6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNHIT6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znhit6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNHIT6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNHIT6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znhit6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znhit6 (zinc finger HIT-type containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZNHIT6 (zinc finger HIT-type containing 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Znhit6 (zinc finger, HIT type 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znhit6 (zinc finger HIT-type containing 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znhit6 (zinc finger HIT-type containing 6)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1463	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1463	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	BCD1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	zhit-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	zhit-3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	znhit6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	237,147,014 - 237,178,279 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	237,146,992 - 237,178,334 (+)	Ensembl				GRCr8
mRatBN7.2	2	234,486,686 - 234,517,952 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	234,486,704 - 234,517,960 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	242,283,835 - 242,315,731 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	240,174,387 - 240,206,269 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	235,041,451 - 235,073,351 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	251,453,503 - 251,484,760 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	251,453,644 - 251,484,759 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	269,981,414 - 270,012,985 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	243,746,296 - 243,778,317 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	226,474,975 - 226,506,057 (+)	NCBI		Celera
RGSC_v3.1	2	243,732,952 - 243,764,916 (+)	NCBI
Cytogenetic Map	2	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

captan (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dioxygen (ISO)

doxorubicin (ISO)

ethyl methanesulfonate (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

folpet (ISO)

formaldehyde (ISO)

FR900359 (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

ketamine (EXP)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

PCB138 (ISO)

pentachlorophenol (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

box C/D snoRNP assembly (IBA,IEA,ISO)

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IBA)

protein complex oligomerization (IEA,ISO)

ribosome biogenesis (IEA)

snoRNA localization (IEA,ISO)

Cellular Component

nucleus (IBA)

pre-snoRNP complex (IBA,IEA,ISO)

Molecular Function

ATPase binding (IEA,ISO)

enzyme binding (IEA,ISO)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

TFIID-class transcription factor complex binding (IEA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17636026	PMID:19056867	PMID:22082260	PMID:23382074

Genomics

Comparative Map Data

Znhit6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	237,147,014 - 237,178,279 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	237,146,992 - 237,178,334 (+)	Ensembl				GRCr8
mRatBN7.2	2	234,486,686 - 234,517,952 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	234,486,704 - 234,517,960 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	242,283,835 - 242,315,731 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	240,174,387 - 240,206,269 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	235,041,451 - 235,073,351 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	251,453,503 - 251,484,760 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	251,453,644 - 251,484,759 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	269,981,414 - 270,012,985 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	243,746,296 - 243,778,317 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	226,474,975 - 226,506,057 (+)	NCBI		Celera
RGSC_v3.1	2	243,732,952 - 243,764,916 (+)	NCBI
Cytogenetic Map	2	q44	NCBI

ZNHIT6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	85,649,417 - 85,708,433 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	85,649,417 - 85,708,433 (-)	Ensembl			hg38	GRCh38
GRCh37	1	86,115,100 - 86,174,116 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	85,891,079 - 85,946,689 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	84,359,216 - 84,418,317 (-)	NCBI		Celera
Cytogenetic Map	1	p22.3	NCBI
HuRef	1	84,225,885 - 84,285,169 (-)	NCBI		HuRef
CHM1_1	1	86,230,534 - 86,289,502 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	85,490,231 - 85,549,278 (-)	NCBI		T2T-CHM13v2.0

Znhit6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	145,281,943 - 145,313,570 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	145,281,960 - 145,310,550 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	145,576,201 - 145,605,245 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	145,576,205 - 145,604,795 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	145,239,172 - 145,268,209 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	145,513,591 - 145,542,631 (+)	NCBI		MGSCv36	mm8
Celera	3	152,028,856 - 152,057,972 (+)	NCBI		Celera
Cytogenetic Map	3	H2	NCBI
cM Map	3	69.89	NCBI

Znhit6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	8,309,521 - 8,362,951 (+)	Ensembl
ChiLan1.0	NW_004955423	8,309,533 - 8,359,601 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZNHIT6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	141,221,467 - 141,277,316 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	140,376,850 - 140,432,505 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	118,213,412 - 118,269,103 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	87,068,740 - 87,124,138 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	87,068,740 - 87,124,138 (-)	Ensembl			panPan2	panpan1.1

ZNHIT6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	62,335,344 - 62,393,418 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	62,335,275 - 62,418,564 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	64,984,742 - 65,069,699 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	62,876,255 - 62,961,241 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	62,876,359 - 62,934,234 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	62,406,460 - 62,491,383 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	62,373,858 - 62,458,753 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	62,878,404 - 62,963,596 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znhit6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	96,211,261 - 96,272,623 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936608	33,384 - 93,335 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936608	33,425 - 94,291 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNHIT6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	130,298,280 - 130,386,955 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	130,298,109 - 130,409,569 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	142,854,256 - 142,875,043 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	4	142,666,132 - 142,794,709 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNHIT6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	47,666,100 - 47,720,015 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	47,666,297 - 47,722,160 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	70,088,520 - 70,143,107 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znhit6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	11,767,896 - 11,817,031 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624742	11,767,738 - 11,818,060 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znhit6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	15,276,419 - 15,304,312 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Znhit6
185 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	49
Count of miRNA genes:	47
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000041897
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
1331767	Hrtrt12	Heart rate QTL 12	3.373		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	221088977	243501206	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	210956252	251712708	Rat
8693697	Alc36	Alcohol consumption QTL 36	2	0.592	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	2	219814164	239320906	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	214404877	251712708	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
2293833	Kiddil8	Kidney dilation QTL 8	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	220274283	249795005	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	203664411	248664411	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204795005	249795005	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	214404877	251712708	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	214404877	251712708	Rat
2313073	Bmd75	Bone mineral density QTL 75	4.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	2	218051934	251712708	Rat
8693622	Alc26	Alcohol consumption QTL 26	2.4	0.667	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	2	223810546	243965570	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	214404877	251712708	Rat
2293844	Kiddil7	Kidney dilation QTL 7	3.5		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	220274283	249795005	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	196140964	251540988	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	214404877	251712708	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	205135267	250135267	Rat

Markers in Region

RH133229

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	234,507,084 - 234,507,265 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	251,473,899 - 251,474,079	NCBI	Rnor6.0
Rnor_5.0	2	270,001,689 - 270,001,869	UniSTS	Rnor5.0
RGSC_v3.4	2	243,767,021 - 243,767,201	UniSTS	RGSC3.4
Celera	2	226,495,170 - 226,495,350	UniSTS
RH 3.4 Map	2	1580.9	UniSTS
Cytogenetic Map	2	q44	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106203	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_591336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC161957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000041897 ⟹ ENSRNOP00000041785

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	237,147,025 - 237,178,334 (+)	Ensembl
mRatBN7.2 Ensembl	2	234,486,831 - 234,517,947 (+)	Ensembl
Rnor_6.0 Ensembl	2	251,453,644 - 251,484,759 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098863 ⟹ ENSRNOP00000092127

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	237,147,025 - 237,171,474 (+)	Ensembl
mRatBN7.2 Ensembl	2	234,486,864 - 234,514,553 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116542 ⟹ ENSRNOP00000082388

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	237,147,025 - 237,168,232 (+)	Ensembl
mRatBN7.2 Ensembl	2	234,486,831 - 234,514,482 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120282 ⟹ ENSRNOP00000089983

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	237,146,992 - 237,178,334 (+)	Ensembl
mRatBN7.2 Ensembl	2	234,486,704 - 234,517,960 (+)	Ensembl

RefSeq Acc Id:

NM_001106203 ⟹ NP_001099673

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	237,147,158 - 237,178,275 (+)	NCBI
mRatBN7.2	2	234,486,831 - 234,517,948 (+)	NCBI
Rnor_6.0	2	251,453,644 - 251,484,760 (+)	NCBI
Rnor_5.0	2	269,981,414 - 270,012,985 (+)	NCBI
RGSC_v3.4	2	243,746,296 - 243,778,317 (+)	RGD
Celera	2	226,474,975 - 226,506,057 (+)	RGD

Sequence:

show sequence

GGAGTGGCAGCTTCGGCCTAGGCTCGTGAGCTGATGGAGTTTGCAGCTGAGAAAGAAGGGACTC
CGGGAGGAGGTCCCCAGAGGGTAGCTGAGGGGGCGCGGCCGAGGCCTGCGGCTGGTGGGGAGGG
AGCCGGGGACTTAGGTGGGAGCCCCGAAGCTGACGATGGAGAGGAGAGGAACGGACTGACAGGA
ATTAAGACCACAGAGGATGCGGAGGAGATAAAGATGGACTTAGCTGTGGTGAAGCAGGAAGTAG
TGGACTGGTCGGATTTAGACGGTGATATTTCGGATAGCCACTGGGTAAAGCAGGAGGTGGAGGG
CGGGCCTGAGGTGAAGGCTGAGAAAGACGTGTTGGAGGTGAAGCAGGAGGCGGATAGTAGCCTG
GTGGTGAAAGAAGAGGAGGTGGATGAGCCAGAAGTAAAGGAAGAGAAAGTGAAGGTGAAGGAGG
AGGTAACGGACTGGGAAGAAGCGAAGGAGGAGGACTTGAACGTAAAACAGGAGTTGTTTGTTGG
TCAGAACGTAAAGGAGGAGCAGGTGATGGATAGAGTGCCCGTAAAAGAAGAGGATTGCTTCAAG
AGAGAAGTGACGGAAGACACGAAGGTGAAGGAAGAGCCGCAGATGAATCCCCGAGTGGGCTGCA
AGAGGAAATTGGCCATGTCGAGGTGTGAGACTTGTGGCACGGAAGAAGCAAAGTACAGATGTCC
ACGCTGCATGCGGTACTCCTGCAGTTTGCCCTGTGTGAAGAGACACAAAGCAGAGCTGATGTGC
AGCGGCGTGCGGGATAAGACTGCCTATGTCTCTCTGCAGCGCTTTACTGAGATGAACCTCCTGA
GCGACTATCGGTTTTTGGAAGACGTGGCGAGGACAGCAGACCGGGTGTCAAGAGATATTTTCTT
GACAAGACCAAAGCGCAAGAAATATCTGCTCTTTTTGAAGAATCGTGCCCGGAAGCAAGGTGTT
TACTTGAGGCTGCTACCCAGTGGGTTCAGCAAGAGGAGAGAGAACTCGACGGTTTTTGACCATA
GGAATCAGCAGTTTTGTTGGCACGTAAAGCTCCAGTTCCCTCAGAGCCAGGCGGAGTATGTAGA
GAAAAGAGTACCAGATGATAAAACCATTAATGAAATTCTAAAACCTTACATCGATCCCGAAAAG
TCTGATCCTGTGATTCGTCAGAGATTGAAAGCCTACACACAGTCCCAGACTGGGGTCCAAATTT
TAATGAGGGTCGAAAATATGCAACAAAATTTGATAAGGTATTATGAACTGGATCCTTCCAAAAG
TCTTGTAAACAACTTGAGGAACAAAGTGATCATTGAGTATCCGACTCTGCATGTGGTATTGAAA
GGCTGCAGTAATGACATGCAGCTTCTTCACCAAGTGAAAAGTGAGTCTGCCCAGAAGCTTGGCA
ATGGAGATTAAGCCCTGTGGAAGAAGGTGGAAGTCCGTCCCCCGGGGTCAAGAAGATTGTGTAT
GCTGGACTGCGGGCGACTGGGTCTGTCAGGAGCTCGGAGTCTGTTGTTTGTCTGAAAAGTAATT
AAATAGCATTACTTTTTTGGAGAGGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039101877 ⟹ XP_038957805

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	237,147,014 - 237,171,474 (+)	NCBI
mRatBN7.2	2	234,486,831 - 234,514,076 (+)	NCBI

RefSeq Acc Id:

XM_039101879 ⟹ XP_038957807

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	237,147,015 - 237,178,279 (+)	NCBI
mRatBN7.2	2	234,486,720 - 234,517,943 (+)	NCBI

RefSeq Acc Id:

XM_039101880 ⟹ XP_038957808

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	237,147,014 - 237,178,279 (+)	NCBI
mRatBN7.2	2	234,486,686 - 234,517,952 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099673	(Get FASTA)	NCBI Sequence Viewer
	XP_038957805	(Get FASTA)	NCBI Sequence Viewer
	XP_038957807	(Get FASTA)	NCBI Sequence Viewer
	XP_038957808	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61957	(Get FASTA)	NCBI Sequence Viewer
	EDL82402	(Get FASTA)	NCBI Sequence Viewer
	EDL82403	(Get FASTA)	NCBI Sequence Viewer
	EDL82404	(Get FASTA)	NCBI Sequence Viewer
	EDL82405	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000041785
	ENSRNOP00000041785.3
	ENSRNOP00000082388.2
	ENSRNOP00000089983.2
	ENSRNOP00000092127
	ENSRNOP00000092127.2

RefSeq Acc Id:

NP_001099673 ⟸ NM_001106203

- UniProtKB:

B1WC05 (UniProtKB/TrEMBL), F7F2A4 (UniProtKB/TrEMBL), A0A8I5ZXU8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEFAAEKEGTPGGGPQRVAEGARPRPAAGGEGAGDLGGSPEADDGEERNGLTGIKTTEDAEEIK
MDLAVVKQEVVDWSDLDGDISDSHWVKQEVEGGPEVKAEKDVLEVKQEADSSLVVKEEEVDEPE
VKEEKVKVKEEVTDWEEAKEEDLNVKQELFVGQNVKEEQVMDRVPVKEEDCFKREVTEDTKVKE
EPQMNPRVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKRHKAELMCSGVRDKTAYVS
LQRFTEMNLLSDYRFLEDVARTADRVSRDIFLTRPKRKKYLLFLKNRARKQGVYLRLLPSGFSK
RRENSTVFDHRNQQFCWHVKLQFPQSQAEYVEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKA
YTQSQTGVQILMRVENMQQNLIRYYELDPSKSLVNNLRNKVIIEYPTLHVVLKGCSNDMQLLHQ
VKSESAQKLGNGD

hide sequence

Ensembl Acc Id:

ENSRNOP00000041785 ⟸ ENSRNOT00000041897

RefSeq Acc Id:	XP_038957808 ⟸ XM_039101880
- Peptide Label:	isoform X3
- UniProtKB:	A6HWB9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957807 ⟸ XM_039101879
- Peptide Label:	isoform X2
- UniProtKB:	A6HWB7 (UniProtKB/TrEMBL), A0A8I6GII8 (UniProtKB/TrEMBL), A6HWB8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957805 ⟸ XM_039101877
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZXU8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000082388 ⟸ ENSRNOT00000116542

Ensembl Acc Id:

ENSRNOP00000089983 ⟸ ENSRNOT00000120282

Ensembl Acc Id:

ENSRNOP00000092127 ⟸ ENSRNOT00000098863

Protein Domains

HIT-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WC05-F1-model_v2	AlphaFold	B1WC05	1-461	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691807

Promoter ID:

EPDNEW_R2332

Type:

initiation region

Name:

Znhit6_1

Description:

zinc finger, HIT-type containing 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	251,453,547 - 251,453,607	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308723	AgrOrtholog
BioCyc Gene	G2FUF-50928	BioCyc
Ensembl Genes	ENSRNOG00000030049	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000041897	ENTREZGENE
	ENSRNOT00000041897.5	UniProtKB/TrEMBL
	ENSRNOT00000098863	ENTREZGENE
	ENSRNOT00000098863.2	UniProtKB/TrEMBL
	ENSRNOT00000116542.2	UniProtKB/TrEMBL
	ENSRNOT00000120282.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.60.190	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9027306	IMAGE-MGC_LOAD
InterPro	BCD1	UniProtKB/TrEMBL
	Znf_HIT	UniProtKB/TrEMBL
KEGG Report	rno:292160	UniProtKB/TrEMBL
MGC_CLONE	MGC:187759	IMAGE-MGC_LOAD
NCBI Gene	292160	ENTREZGENE
PANTHER	BOX C/D SNORNA PROTEIN 1	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	BCD1	UniProtKB/TrEMBL
	zf-HIT	UniProtKB/TrEMBL
PhenoGen	Znhit6	PhenoGen
PROSITE	ZF_HIT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030049	RatGTEx
Superfamily-SCOP	HIT/MYND zinc finger-like	UniProtKB/TrEMBL
UniProt	A0A8I5ZXU8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGK2_RAT	UniProtKB/TrEMBL
	A0A8I6GII8	ENTREZGENE, UniProtKB/TrEMBL
	A6HWB7	ENTREZGENE, UniProtKB/TrEMBL
	A6HWB8	ENTREZGENE, UniProtKB/TrEMBL
	A6HWB9	ENTREZGENE, UniProtKB/TrEMBL
	B1WC05	ENTREZGENE, UniProtKB/TrEMBL
	F7F2A4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-01	Znhit6	zinc finger, HIT-type containing 6	Znhit6	zinc finger, HIT type 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Znhit6	zinc finger, HIT type 6	RGD1308723	similar to hypothetical protein FLJ20729	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1308723	similar to hypothetical protein FLJ20729	RGD1308723_predicted	similar to hypothetical protein FLJ20729 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1308723_predicted	similar to hypothetical protein FLJ20729 (predicted)	LOC292160_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC292160_predicted	similar to hypothetical protein FLJ20729 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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