Crim1 (cysteine rich transmembrane BMP regulator 1) - Rat Genome Database

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Pathways
Gene: Crim1 (cysteine rich transmembrane BMP regulator 1) Rattus norvegicus
Analyze
Symbol: Crim1
Name: cysteine rich transmembrane BMP regulator 1
RGD ID: 1308710
Description: Predicted to enable PDZ domain binding activity. Predicted to act upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in extracellular region and membrane. Orthologous to human CRIM1 (cysteine rich transmembrane BMP regulator 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine-rich motor neuron 1; LOC298744
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,447,983 - 22,622,459 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl622,449,948 - 22,622,416 (-)EnsemblGRCr8
mRatBN7.2616,695,864 - 16,870,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,697,829 - 16,870,259 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx617,006,372 - 17,178,832 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,328,581 - 17,501,056 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,812,112 - 16,987,170 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06788,490 - 962,663 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6788,548 - 960,703 (+)Ensemblrn6Rnor6.0
Rnor_5.06780,568 - 954,493 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46962,024 - 1,141,314 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera616,341,369 - 16,513,685 (-)NCBICelera
RGSC_v3.161,051,003 - 1,141,914 (+)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
chloroprene  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
enniatin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gentamycin  (EXP)
graphene oxide  (ISO)
inulin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel sulfate  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
prednisolone  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23209302   PMID:23376485  


Genomics

Comparative Map Data
Crim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,447,983 - 22,622,459 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl622,449,948 - 22,622,416 (-)EnsemblGRCr8
mRatBN7.2616,695,864 - 16,870,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,697,829 - 16,870,259 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx617,006,372 - 17,178,832 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,328,581 - 17,501,056 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,812,112 - 16,987,170 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06788,490 - 962,663 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6788,548 - 960,703 (+)Ensemblrn6Rnor6.0
Rnor_5.06780,568 - 954,493 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46962,024 - 1,141,314 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera616,341,369 - 16,513,685 (-)NCBICelera
RGSC_v3.161,051,003 - 1,141,914 (+)NCBI
Cytogenetic Map6q12NCBI
CRIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38236,355,778 - 36,551,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl236,355,731 - 36,551,135 (+)Ensemblhg38GRCh38
GRCh37236,582,921 - 36,778,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36236,436,901 - 36,631,782 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34236,495,047 - 36,689,928NCBI
Celera236,424,733 - 36,619,370 (+)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef236,324,018 - 36,518,565 (+)NCBIHuRef
CHM1_1236,512,729 - 36,707,637 (+)NCBICHM1_1
T2T-CHM13v2.0236,362,433 - 36,557,798 (+)NCBIT2T-CHM13v2.0
Crim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,507,602 - 78,684,021 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1778,507,677 - 78,684,021 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381778,200,233 - 78,376,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,200,248 - 78,376,592 (+)Ensemblmm10GRCm38
MGSCv371778,599,588 - 78,775,932 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361778,102,126 - 78,279,372 (+)NCBIMGSCv36mm8
Celera1782,502,178 - 82,678,529 (+)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.09NCBI
Crim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554414,274,611 - 4,420,537 (+)Ensembl
ChiLan1.0NW_0049554414,275,411 - 4,420,537 (+)NCBIChiLan1.0ChiLan1.0
CRIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,927,033 - 90,122,274 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,931,009 - 90,126,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A36,384,964 - 36,580,214 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A37,148,551 - 37,342,933 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,147,108 - 37,340,537 (+)EnsemblpanPan2panpan1.1
CRIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11728,857,702 - 29,042,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1728,857,696 - 29,040,002 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1728,671,528 - 28,856,142 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01729,507,397 - 29,692,213 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1729,506,861 - 29,692,195 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11728,729,097 - 28,913,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01728,797,081 - 28,981,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,016,015 - 29,200,891 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Crim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,958,263 - 43,137,956 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366631,623,355 - 1,803,448 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366631,623,655 - 1,803,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,612,659 - 103,815,556 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13103,612,231 - 103,815,493 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23110,257,604 - 110,477,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,868,523 - 71,067,086 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,870,839 - 71,067,215 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604540,894,800 - 41,091,278 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,035,725 - 18,216,464 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473818,036,199 - 18,216,086 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Crim1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1714,843,524 - 15,021,163 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Crim1
891 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:245
Count of miRNA genes:178
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000005983
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)62228825727729050Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)62228825732981219Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat

Markers in Region
RH134028  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8622,448,047 - 22,448,266 (+)Marker Load Pipeline
mRatBN7.2616,695,928 - 16,696,147 (-)MAPPERmRatBN7.2
Rnor_6.06962,385 - 962,603NCBIRnor6.0
Rnor_5.06954,210 - 954,428UniSTSRnor5.0
RGSC_v3.461,142,996 - 1,143,214UniSTSRGSC3.4
Celera616,339,469 - 16,339,687UniSTS
RH 3.4 Map625.7UniSTS
Cytogenetic Map6q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005983   ⟹   ENSRNOP00000005983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,449,948 - 22,622,416 (-)Ensembl
mRatBN7.2 Ensembl616,697,829 - 16,870,259 (-)Ensembl
Rnor_6.0 Ensembl6788,548 - 960,703 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094931   ⟹   ENSRNOP00000088000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,449,948 - 22,622,416 (-)Ensembl
mRatBN7.2 Ensembl616,697,829 - 16,870,259 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124837   ⟹   ENSRNOP00000108338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,449,948 - 22,622,416 (-)Ensembl
RefSeq Acc Id: NM_001169103   ⟹   NP_001162574
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,449,948 - 22,622,416 (-)NCBI
mRatBN7.2616,697,829 - 16,870,259 (-)NCBI
Rnor_6.06788,548 - 960,703 (+)NCBI
Rnor_5.06780,568 - 954,493 (+)NCBI
RGSC_v3.46962,024 - 1,141,314 (+)RGD
Celera616,341,369 - 16,513,685 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239623   ⟹   XP_006239685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,447,983 - 22,622,459 (-)NCBI
mRatBN7.2616,695,864 - 16,870,264 (-)NCBI
Rnor_6.06788,490 - 962,663 (+)NCBI
Rnor_5.06780,568 - 954,493 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239625   ⟹   XP_006239687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,447,983 - 22,622,459 (-)NCBI
mRatBN7.2616,695,864 - 16,870,262 (-)NCBI
Rnor_6.06788,490 - 962,663 (+)NCBI
Rnor_5.06780,568 - 954,493 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039111891   ⟹   XP_038967819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,447,983 - 22,622,459 (-)NCBI
mRatBN7.2616,695,864 - 16,870,262 (-)NCBI
RefSeq Acc Id: XM_039111892   ⟹   XP_038967820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,447,983 - 22,539,492 (-)NCBI
mRatBN7.2616,695,864 - 16,787,316 (-)NCBI
RefSeq Acc Id: XM_039111893   ⟹   XP_038967821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,447,983 - 22,582,359 (-)NCBI
mRatBN7.2616,695,864 - 16,830,187 (-)NCBI
RefSeq Acc Id: NP_001162574   ⟸   NM_001169103
- Peptide Label: precursor
- UniProtKB: D4AEK3 (UniProtKB/TrEMBL),   A6H9W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239685   ⟸   XM_006239623
- Peptide Label: isoform X1
- UniProtKB: A6H9W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239687   ⟸   XM_006239625
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A5L9 (UniProtKB/TrEMBL),   A6H9W6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005983   ⟸   ENSRNOT00000005983
RefSeq Acc Id: XP_038967819   ⟸   XM_039111891
- Peptide Label: isoform X3
- UniProtKB: A6H9W6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967821   ⟸   XM_039111893
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038967820   ⟸   XM_039111892
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000088000   ⟸   ENSRNOT00000094931
Ensembl Acc Id: ENSRNOP00000108338   ⟸   ENSRNOT00000124837
Protein Domains
Antistasin-like   IGFBP N-terminal   VWFC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AEK3-F1-model_v2 AlphaFold D4AEK3 1-1037 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694350
Promoter ID:EPDNEW_R4874
Type:initiation region
Name:Crim1_1
Description:cysteine rich transmembrane BMP regulator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06788,551 - 788,611EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308710 AgrOrtholog
BioCyc Gene G2FUF-38481 BioCyc
Ensembl Genes ENSRNOG00000004208 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005983 ENTREZGENE
  ENSRNOT00000005983.7 UniProtKB/TrEMBL
  ENSRNOT00000094931 ENTREZGENE
  ENSRNOT00000094931.2 UniProtKB/TrEMBL
  ENSRNOT00000124837.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.40.20 UniProtKB/TrEMBL
  6.20.200.20 UniProtKB/TrEMBL
  Antistasin, domain 1 UniProtKB/TrEMBL
InterPro CRIM1 UniProtKB/TrEMBL
  CRIM1_C UniProtKB/TrEMBL
  Growth_fac_rcpt_N_dom UniProtKB/TrEMBL
  IGFBP-like UniProtKB/TrEMBL
  Prot_inh_I14/15_hirudin/antisn UniProtKB/TrEMBL
  Prot_inh_I15_antistasin-like UniProtKB/TrEMBL
  VWF_C UniProtKB/TrEMBL
KEGG Report rno:298744 UniProtKB/TrEMBL
NCBI Gene 298744 ENTREZGENE
PANTHER CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/TrEMBL
  CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/TrEMBL
Pfam Antistasin UniProtKB/TrEMBL
  CRIM1_C UniProtKB/TrEMBL
  IGFBP UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
PhenoGen Crim1 PhenoGen
PROSITE ANTISTASIN UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/TrEMBL
  VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004208 RatGTEx
SMART SM00121 UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
Superfamily-SCOP Antihaemostatic UniProtKB/TrEMBL
  FnI-like domain UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8I6A5L9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LSQ0_RAT UniProtKB/TrEMBL
  A6H9W6 ENTREZGENE, UniProtKB/TrEMBL
  D4AEK3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Crim1  cysteine rich transmembrane BMP regulator 1  Crim1  cysteine rich transmembrane BMP regulator 1 (chordin like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Crim1  cysteine rich transmembrane BMP regulator 1 (chordin like)  Crim1_predicted  cysteine-rich motor neuron 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Crim1_predicted  cysteine-rich motor neuron 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED