Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TJAP1 mRNA] | CTD | PMID:31150632 | 17alpha-ethynylestradiol | affects expression | ISO | Tjap1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TJAP1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Tjap1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TJAP1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TJAP1 mRNA | CTD | PMID:17942748 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tjap1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TJAP1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TJAP1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TJAP1 mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TJAP1 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Tjap1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of TJAP1 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TJAP1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TJAP1 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of TJAP1 exon | CTD | PMID:30157460 | aristolochic acid A | increases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TJAP1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TJAP1 gene | CTD | PMID:25304211 | arsane | affects expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Arsenic affects the expression of TJAP1 mRNA | CTD | PMID:33736254 | arsenic atom | affects methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TJAP1 gene | CTD | PMID:25304211 | arsenic atom | affects expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Arsenic affects the expression of TJAP1 mRNA | CTD | PMID:33736254 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TJAP1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TJAP1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TJAP1 5' UTR and Benzo(a)pyrene affects the methylation of TJAP1 exon | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | Tjap1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of TJAP1 promoter | CTD | PMID:27901495 | benzo[e]pyrene | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of TJAP1 exon | CTD | PMID:30157460 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TJAP1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TJAP1 mRNA | CTD | PMID:30816183 more ... | cadmium dichloride | decreases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TJAP1 mRNA and Cadmium Chloride results in decreased expression of TJAP1 protein | CTD | PMID:25851441 | caffeine | decreases phosphorylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TJAP1 protein | CTD | PMID:35688186 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA | CTD | PMID:33854195 | chlorpyrifos | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TJAP1 mRNA | CTD | PMID:37019170 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of TJAP1 mRNA | CTD | PMID:20032058 | dexamethasone | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of TJAP1 mRNA | CTD | PMID:22733784 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of TJAP1 mRNA] | CTD | PMID:20032058 | doxorubicin | decreases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TJAP1 mRNA | CTD | PMID:29803840 | endosulfan | affects expression | EXP | | 6480464 | Endosulfan affects the expression of TJAP1 mRNA | CTD | PMID:31464424 | ethanol | affects expression | ISO | Tjap1 (Mus musculus) | 6480464 | Ethanol affects the expression of TJAP1 mRNA | CTD | PMID:30319688 | fenamidone | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | fenamidone results in increased expression of TJAP1 mRNA | CTD | PMID:27029645 | folic acid | decreases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TJAP1 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | TJAP1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TJAP1 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TJAP1 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA | CTD | PMID:33854195 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA | CTD | PMID:33854195 | ivermectin | decreases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TJAP1 protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Lead affects the expression of TJAP1 mRNA | CTD | PMID:28903495 | methamphetamine | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of TJAP1 mRNA | CTD | PMID:26307267 | methapyrilene | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of TJAP1 exon | CTD | PMID:30157460 | ozone | decreases expression | EXP | | 6480464 | Ozone results in decreased expression of TJAP1 mRNA | CTD | PMID:31397875 | paracetamol | affects expression | ISO | Tjap1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TJAP1 mRNA | CTD | PMID:17562736 | pentachlorophenol | increases expression | ISO | Tjap1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TJAP1 mRNA | CTD | PMID:23892564 | perfluorooctanoic acid | increases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of TJAP1 protein | CTD | PMID:26879310 | tamoxifen | affects expression | ISO | Tjap1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of TJAP1 mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TJAP1 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of TJAP1 mRNA] | CTD | PMID:20032058 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TJAP1 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TJAP1 mRNA] | CTD | PMID:31150632 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA | CTD | PMID:33854195 | valproic acid | decreases methylation | ISO | TJAP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TJAP1 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | TJAP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TJAP1 mRNA | CTD | PMID:25979313 | |