Aaas (aladin WD repeat nucleoporin) - Rat Genome Database

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Gene: Aaas (aladin WD repeat nucleoporin) Rattus norvegicus
Analyze
Symbol: Aaas
Name: aladin WD repeat nucleoporin
RGD ID: 1308701
Description: Predicted to be involved in microtubule bundle formation; mitotic spindle assembly; and nucleocytoplasmic transport. Predicted to act upstream of or within several processes, including glutathione metabolic process; learning; and response to oxidative stress. Predicted to be located in mitotic spindle; nuclear envelope; and spindle pole. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in achalasia and triple-A syndrome. Orthologous to human AAAS (aladin WD repeat nucleoporin); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: achalasia, adrenocortical insufficiency, alacrimia; achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A); Aladin; LOC300259
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,342,901 - 135,362,545 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)EnsemblGRCr8
mRatBN7.27133,464,315 - 133,483,961 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,464,315 - 133,483,961 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7135,225,355 - 135,244,947 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,454,735 - 137,474,327 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,439,883 - 137,459,475 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,937,198 - 143,956,668 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,937,199 - 143,956,668 (-)Ensemblrn6Rnor6.0
Rnor_5.07141,733,240 - 141,751,976 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47141,088,006 - 141,107,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7129,897,723 - 129,917,036 (-)NCBICelera
RGSC_v3.17141,164,476 - 141,184,631 (-)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dioxane  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
N-nitrosodiethylamine  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenytoin  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
propiconazole  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genotypic heterogeneity and clinical phenotype in triple A syndrome: a review of the NIH experience 2000-2005. Brooks BP, etal., Clin Genet. 2005 Sep;68(3):215-21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Identification of the sites of expression of triple A syndrome mRNA in the rat using in situ hybridisation. Storr HL, etal., Neuroscience 2005;131(1):113-23.
Additional References at PubMed
PMID:12730363   PMID:16479006   PMID:19946888   PMID:21630459   PMID:26246606   PMID:27754849  


Genomics

Comparative Map Data
Aaas
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,342,901 - 135,362,545 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)EnsemblGRCr8
mRatBN7.27133,464,315 - 133,483,961 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,464,315 - 133,483,961 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7135,225,355 - 135,244,947 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,454,735 - 137,474,327 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,439,883 - 137,459,475 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,937,198 - 143,956,668 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,937,199 - 143,956,668 (-)Ensemblrn6Rnor6.0
Rnor_5.07141,733,240 - 141,751,976 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47141,088,006 - 141,107,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7129,897,723 - 129,917,036 (-)NCBICelera
RGSC_v3.17141,164,476 - 141,184,631 (-)NCBI
Cytogenetic Map7q36NCBI
AAAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,307,460 - 53,321,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,307,456 - 53,324,864 (-)Ensemblhg38GRCh38
GRCh371253,701,244 - 53,715,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,987,507 - 52,001,648 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341251,987,507 - 52,001,641NCBI
Celera1253,350,517 - 53,364,688 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,742,753 - 50,756,938 (-)NCBIHuRef
CHM1_11253,667,677 - 53,682,600 (-)NCBICHM1_1
T2T-CHM13v2.01253,273,162 - 53,287,327 (-)NCBIT2T-CHM13v2.0
Aaas
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,246,682 - 102,259,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,246,687 - 102,259,206 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3815102,338,247 - 102,350,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,338,252 - 102,350,771 (-)Ensemblmm10GRCm38
MGSCv3715102,168,678 - 102,181,190 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615102,166,290 - 102,178,732 (-)NCBIMGSCv36mm8
Celera15104,495,249 - 104,507,826 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.49NCBI
Aaas
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458567,518 - 577,372 (-)Ensembl
ChiLan1.0NW_004955458567,487 - 577,228 (-)NCBIChiLan1.0ChiLan1.0
AAAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,864,475 - 40,878,699 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,861,295 - 40,875,460 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,432,834 - 35,446,969 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,214,444 - 36,227,886 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,214,444 - 36,227,886 (+)EnsemblpanPan2panpan1.1
AAAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,889,078 - 1,900,097 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,889,141 - 1,900,094 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2744,349,182 - 44,360,102 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0271,893,644 - 1,904,560 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,881,916 - 1,904,554 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,911,863 - 1,922,895 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,896,881 - 1,907,795 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,749,806 - 44,760,823 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Aaas
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,559,999 - 62,575,281 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,588,786 - 10,604,861 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,589,549 - 10,604,831 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AAAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,526,076 - 18,537,830 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1518,526,070 - 18,537,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,961,802 - 18,973,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AAAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,424,469 - 49,432,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,629,094 - 196,647,843 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aaas
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,419,835 - 1,432,741 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249041,419,809 - 1,432,117 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Aaas
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11260,731,116 - 260,743,383 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:35
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000018809
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)7132099939137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
33.MMHAP86FRC12.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,471,893 - 133,472,020 (+)MAPPERmRatBN7.2
Rnor_6.07143,944,778 - 143,944,904NCBIRnor6.0
Rnor_5.07141,740,820 - 141,740,946UniSTSRnor5.0
RGSC_v3.47141,095,585 - 141,095,711UniSTSRGSC3.4
Celera7129,905,293 - 129,905,419UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018809   ⟹   ENSRNOP00000018808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)Ensembl
mRatBN7.2 Ensembl7133,464,315 - 133,483,961 (-)Ensembl
Rnor_6.0 Ensembl7143,937,199 - 143,956,668 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096778   ⟹   ENSRNOP00000077779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)Ensembl
mRatBN7.2 Ensembl7133,464,324 - 133,477,483 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116335   ⟹   ENSRNOP00000088974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)Ensembl
mRatBN7.2 Ensembl7133,464,315 - 133,483,961 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126788   ⟹   ENSRNOP00000100285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,342,901 - 135,352,334 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000146313   ⟹   ENSRNOP00000102972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,342,901 - 135,362,545 (-)Ensembl
RefSeq Acc Id: NM_001106795   ⟹   NP_001100265
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,901 - 135,362,545 (-)NCBI
mRatBN7.27133,464,315 - 133,483,961 (-)NCBI
Rnor_6.07143,937,199 - 143,956,668 (-)NCBI
Rnor_5.07141,733,240 - 141,751,976 (-)NCBI
RGSC_v3.47141,088,006 - 141,107,581 (-)RGD
Celera7129,897,723 - 129,917,036 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242387   ⟹   XP_006242449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,108 (-)NCBI
mRatBN7.27133,464,316 - 133,477,522 (-)NCBI
Rnor_6.07143,937,198 - 143,950,405 (-)NCBI
Rnor_5.07141,733,240 - 141,751,976 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765704   ⟹   XP_008763926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,100 (-)NCBI
mRatBN7.27133,464,316 - 133,477,524 (-)NCBI
Rnor_6.07143,937,198 - 143,950,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765705   ⟹   XP_008763927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,100 (-)NCBI
mRatBN7.27133,464,316 - 133,477,524 (-)NCBI
Rnor_6.07143,937,198 - 143,950,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063263387   ⟹   XP_063119457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,101 (-)NCBI
RefSeq Acc Id: XM_063263388   ⟹   XP_063119458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,101 (-)NCBI
RefSeq Acc Id: XM_063263389   ⟹   XP_063119459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,342,910 - 135,356,100 (-)NCBI
RefSeq Acc Id: XR_010052964
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,343,553 - 135,356,107 (-)NCBI
RefSeq Acc Id: NP_001100265   ⟸   NM_001106795
- UniProtKB: D3ZNS8 (UniProtKB/TrEMBL),   A6KCU9 (UniProtKB/TrEMBL),   A0A8I5YCH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242449   ⟸   XM_006242387
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008763926   ⟸   XM_008765704
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008763927   ⟸   XM_008765705
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000018808   ⟸   ENSRNOT00000018809
Ensembl Acc Id: ENSRNOP00000088974   ⟸   ENSRNOT00000116335
Ensembl Acc Id: ENSRNOP00000077779   ⟸   ENSRNOT00000096778
RefSeq Acc Id: XP_063119458   ⟸   XM_063263388
- Peptide Label: isoform X2
- UniProtKB: A0A8I5YCH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119457   ⟸   XM_063263387
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YCH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119459   ⟸   XM_063263389
- Peptide Label: isoform X3
- UniProtKB: A0A8I5YCH6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100285   ⟸   ENSRNOT00000126788
Ensembl Acc Id: ENSRNOP00000102972   ⟸   ENSRNOT00000146313
Protein Domains
Aladin seven-bladed propeller

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZNS8-F1-model_v2 AlphaFold D3ZNS8 1-546 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308701 AgrOrtholog
BioCyc Gene G2FUF-31939 BioCyc
Ensembl Genes ENSRNOG00000013445 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018809 ENTREZGENE
  ENSRNOT00000018809.8 UniProtKB/TrEMBL
  ENSRNOT00000096778.2 UniProtKB/TrEMBL
  ENSRNOT00000116335.2 UniProtKB/TrEMBL
  ENSRNOT00000126788.1 UniProtKB/TrEMBL
  ENSRNOT00000146313 ENTREZGENE
  ENSRNOT00000146313.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Aladin UniProtKB/TrEMBL
  Beta-prop_Aladin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:300259 UniProtKB/TrEMBL
NCBI Gene 300259 ENTREZGENE
PANTHER ALADIN UniProtKB/TrEMBL
  PTHR14494 UniProtKB/TrEMBL
Pfam Beta-prop_Aladin UniProtKB/TrEMBL
PhenoGen Aaas PhenoGen
RatGTEx ENSRNOG00000013445 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I5YCH6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJW8_RAT UniProtKB/TrEMBL
  A0ABK0LBY3_RAT UniProtKB/TrEMBL
  A0ABK0LGH8_RAT UniProtKB/TrEMBL
  A6KCU9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZNS8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Aaas  aladin WD repeat nucleoporin  Aaas  achalasia, adrenocortical insufficiency, alacrimia  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-28 Aaas  achalasia, adrenocortical insufficiency, alacrimia  Aaas  achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Aaas  achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)  Aaas  achalasia, adrenocortical insufficiency, alacrimia  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Aaas  achalasia, adrenocortical insufficiency, alacrimia  Aaas_predicted  achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Aaas_predicted  achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) (predicted)      Symbol and Name status set to approved 70820 APPROVED