Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ap3d1 | Rat | Hermansky-Pudlak syndrome | | ISO | AP3D1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ap3d1 | Rat | Hermansky-Pudlak syndrome | | ISO | AP3D1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. | Asensio CS, etal., Dev Cell. 2013 Nov 25;27(4):425-37. doi: 10.1016/j.devcel.2013.10.007. Epub 2013 Nov 7. |
| 2. | Adaptor protein complexes 1 and 3 are essential for generation of synaptic vesicles from activity-dependent bulk endosomes. | Cheung G and Cousin MA, J Neurosci. 2012 Apr 25;32(17):6014-23. doi: 10.1523/JNEUROSCI.6305-11.2012. |
| 3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| PMID:11588176 | PMID:12477932 | PMID:14557411 | PMID:15860731 | PMID:16162817 | PMID:17349999 | PMID:17897319 | PMID:19144828 | PMID:19946888 | PMID:20089890 | PMID:20847273 | PMID:21998198 |
| PMID:22511774 | PMID:23146885 | PMID:24217640 |
| Ap3d1 (Rattus norvegicus - Norway rat) |
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| AP3D1 (Homo sapiens - human) |
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| Ap3d1 (Mus musculus - house mouse) |
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| Ap3d1 (Chinchilla lanigera - long-tailed chinchilla) |
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| AP3D1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| AP3D1 (Canis lupus familiaris - dog) |
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| Ap3d1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| AP3D1 (Sus scrofa - pig) |
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| AP3D1 (Chlorocebus sabaeus - green monkey) |
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| Ap3d1 (Heterocephalus glaber - naked mole-rat) |
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| Ap3d1 (Rattus rattus - black rat) |
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Variants in Ap3d1
171 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| RH124553 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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| 16 | 12 | 67 | 164 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 143 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001100719 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_039079008 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063263422 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063263423 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AC098115 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| BC086368 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC099147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC169097 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474029 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000025878 ⟹ ENSRNOP00000025878 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000095433 ⟹ ENSRNOP00000095136 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000111908 ⟹ ENSRNOP00000084637 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001100719 ⟹ NP_001094189 | ||||||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039079008 ⟹ XP_038934936 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063263422 ⟹ XP_063119492 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063263423 ⟹ XP_063119493 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001094189 | (Get FASTA) | NCBI Sequence Viewer |
| XP_038934936 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063119492 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063119493 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH86368 | (Get FASTA) | NCBI Sequence Viewer |
| AAH99147 | (Get FASTA) | NCBI Sequence Viewer | |
| AAI69097 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL89242 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL89243 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000025878 | ||
| ENSRNOP00000025878.5 | |||
| ENSRNOP00000084637.1 | |||
| ENSRNOP00000095136.1 |
| RefSeq Acc Id: | NP_001094189 ⟸ NM_001100719 |
| - UniProtKB: | B5DFK6 (UniProtKB/TrEMBL), F7F0K5 (UniProtKB/TrEMBL), A0A8I6AM24 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000025878 ⟸ ENSRNOT00000025878 |
| RefSeq Acc Id: | XP_038934936 ⟸ XM_039079008 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A6K8H3 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000084637 ⟸ ENSRNOT00000111908 |
| Ensembl Acc Id: | ENSRNOP00000095136 ⟸ ENSRNOT00000095433 |
| RefSeq Acc Id: | XP_063119492 ⟸ XM_063263422 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A8I6AM24 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063119493 ⟸ XM_063263423 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I6AM24 (UniProtKB/TrEMBL) |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-B5DFK6-F1-model_v2 | AlphaFold | B5DFK6 | 1-1204 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13695007 | ||||||||
| Promoter ID: | EPDNEW_R5532 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Ap3d1_1 | ||||||||
| Description: | adaptor-related protein complex 3, delta 1 subunit | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1308659 | AgrOrtholog |
| BioCyc Gene | G2FUF-34964 | BioCyc |
| Ensembl Genes | ENSRNOG00000018977 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000025878 | ENTREZGENE |
| ENSRNOT00000025878.7 | UniProtKB/TrEMBL | |
| ENSRNOT00000095433.2 | UniProtKB/TrEMBL | |
| ENSRNOT00000111908.2 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.25.10.10 | UniProtKB/TrEMBL |
| Longin domain | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7112159 | IMAGE-MGC_LOAD |
| IMAGE:7365585 | IMAGE-MGC_LOAD | |
| InterPro | AP3_complex_dsu | UniProtKB/TrEMBL |
| AP3D_dom_metazoa | UniProtKB/TrEMBL | |
| ARM-like | UniProtKB/TrEMBL | |
| ARM-type_fold | UniProtKB/TrEMBL | |
| Clathrin/coatomer_adapt-like_N | UniProtKB/TrEMBL | |
| KEGG Report | rno:314633 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:105844 | IMAGE-MGC_LOAD |
| MGC:116299 | IMAGE-MGC_LOAD | |
| NCBI Gene | 314633 | ENTREZGENE |
| PANTHER | AP-3 COMPLEX SUBUNIT DELTA-1 | UniProtKB/TrEMBL |
| PTHR22781 | UniProtKB/TrEMBL | |
| Pfam | Adaptin_N | UniProtKB/TrEMBL |
| AP3D1 | UniProtKB/TrEMBL | |
| PhenoGen | Ap3d1 | PhenoGen |
| PIRSF | AP3_complex_delta | UniProtKB/TrEMBL |
| RatGTEx | ENSRNOG00000018977 | RatGTEx |
| SMART | BLVR | UniProtKB/TrEMBL |
| Superfamily-SCOP | ARM-type_fold | UniProtKB/TrEMBL |
| UniProt | A0A8I6AM24 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A8I6GAS3_RAT | UniProtKB/TrEMBL | |
| A6K8H3 | ENTREZGENE, UniProtKB/TrEMBL | |
| B5DFK6 | ENTREZGENE, UniProtKB/TrEMBL | |
| F7F0K5 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q4FZT4_RAT | UniProtKB/TrEMBL | |
| Q5RK16_RAT | UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2018-05-03 | Ap3d1 | adaptor related protein complex 3 subunit delta 1 | Ap3d1 | adaptor-related protein complex 3, delta 1 subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2006-03-30 | Ap3d1 | adaptor-related protein complex 3, delta 1 subunit | Ap3d | adaptor-related protein complex 3, delta subunit | Symbol and Name updated | 1299863 | APPROVED |
| 2005-12-06 | Ap3d | adaptor-related protein complex 3, delta subunit | Ap3d_predicted | adaptor-related protein complex 3, delta subunit (predicted) | Symbol and Name updated | 1559027 | APPROVED |
| 2005-01-12 | Ap3d_predicted | adaptor-related protein complex 3, delta subunit (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |