Ttc3 (tetratricopeptide repeat domain 3) - Rat Genome Database

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Pathways
Gene: Ttc3 (tetratricopeptide repeat domain 3) Rattus norvegicus
Analyze
Symbol: Ttc3
Name: tetratricopeptide repeat domain 3
RGD ID: 1308654
Description: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in negative regulation of cell differentiation; protein K48-linked ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus and vacuole. Orthologous to human TTC3 (tetratricopeptide repeat domain 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase TTC3; LOC360702; RING-type E3 ubiquitin transferase TTC3; TPR repeat protein D
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,158,766 - 47,258,612 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1147,158,792 - 47,258,418 (+)EnsemblGRCr8
mRatBN7.21133,689,119 - 33,788,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,688,952 - 33,788,975 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1142,344,160 - 42,443,843 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,015,528 - 35,115,203 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01134,163,713 - 34,263,530 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,598,324 - 34,739,986 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,598,492 - 34,738,791 (+)Ensemblrn6Rnor6.0
Rnor_5.01138,186,073 - 38,331,635 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41134,617,072 - 34,659,043 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1134,661,453 - 34,760,646 (-)NCBICelera
RGSC_v3.11134,673,302 - 34,715,290 (+)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
disodium selenite  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gamma-tocopherol  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nefazodone  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(I:C)  (EXP)
propiconazole  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
theophylline  (ISO)
tocopherol  (ISO)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
Golgi apparatus  (IEA)
nucleus  (IEA,ISO)
vacuole  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17488780   PMID:20059950   PMID:24695496  


Genomics

Comparative Map Data
Ttc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,158,766 - 47,258,612 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1147,158,792 - 47,258,418 (+)EnsemblGRCr8
mRatBN7.21133,689,119 - 33,788,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,688,952 - 33,788,975 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1142,344,160 - 42,443,843 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,015,528 - 35,115,203 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01134,163,713 - 34,263,530 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,598,324 - 34,739,986 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,598,492 - 34,738,791 (+)Ensemblrn6Rnor6.0
Rnor_5.01138,186,073 - 38,331,635 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41134,617,072 - 34,659,043 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1134,661,453 - 34,760,646 (-)NCBICelera
RGSC_v3.11134,673,302 - 34,715,290 (+)NCBI
Cytogenetic Map11q11NCBI
TTC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382137,073,254 - 37,203,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2137,073,226 - 37,203,112 (+)Ensemblhg38GRCh38
GRCh372138,445,554 - 38,575,419 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362137,367,441 - 37,497,278 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342137,377,116 - 37,497,276NCBI
Celera2123,643,936 - 23,773,795 (+)NCBICelera
Cytogenetic Map21q22.13NCBI
HuRef2123,921,184 - 24,051,240 (+)NCBIHuRef
CHM1_12138,007,318 - 38,137,162 (+)NCBICHM1_1
T2T-CHM13v2.02135,455,436 - 35,585,344 (+)NCBIT2T-CHM13v2.0
Ttc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391694,171,479 - 94,270,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1694,171,477 - 94,270,202 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381694,370,625 - 94,469,222 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1694,370,618 - 94,469,343 (+)Ensemblmm10GRCm38
MGSCv371694,592,346 - 94,690,828 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361694,492,710 - 94,578,019 (+)NCBIMGSCv36mm8
Celera1695,457,930 - 95,557,093 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.18NCBI
Ttc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540736,205,465 - 36,276,817 (+)Ensembl
ChiLan1.0NW_00495540736,175,312 - 36,307,250 (+)NCBIChiLan1.0ChiLan1.0
TTC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22233,185,308 - 33,314,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12128,045,615 - 28,175,048 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02123,435,041 - 23,564,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12136,789,699 - 36,919,061 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2136,803,826 - 36,917,527 (+)EnsemblpanPan2panpan1.1
TTC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13132,239,895 - 32,348,182 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3132,213,438 - 32,347,195 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3131,292,296 - 31,409,057 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03131,534,031 - 31,652,307 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3131,533,996 - 31,652,306 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13131,401,977 - 31,518,445 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03131,415,038 - 31,531,809 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,905,544 - 32,022,318 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ttc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497131,743,771 - 31,863,040 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365005,647,331 - 5,724,089 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365005,604,783 - 5,724,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13200,707,866 - 200,812,436 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113200,695,624 - 200,821,920 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213210,785,849 - 210,901,277 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1281,048,675 - 81,168,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660548,894,248 - 9,014,236 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474526,446,014 - 26,565,998 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ttc3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1450,171,755 - 50,271,146 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ttc3
672 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:31
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000065600
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
BF406168  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q11UniSTS
Ttc3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,761,770 - 33,762,029 (+)MAPPERmRatBN7.2
Rnor_6.01134,693,712 - 34,693,970NCBIRnor6.0
Rnor_5.01138,285,118 - 38,285,376UniSTSRnor5.0
Celera1134,688,396 - 34,688,654UniSTS
Cytogenetic Map11q11UniSTS
RH133110  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q11UniSTS
RH133719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22047,357,281 - 47,357,492 (-)MAPPERmRatBN7.2
mRatBN7.22047,357,281 - 47,357,492 (+)MAPPERmRatBN7.2
Rnor_6.02048,856,044 - 48,856,254NCBIRnor6.0
Rnor_6.01134,697,493 - 34,697,703NCBIRnor6.0
Rnor_5.02050,498,479 - 50,498,689UniSTSRnor5.0
Rnor_5.01138,288,899 - 38,289,109UniSTSRnor5.0
RGSC_v3.42047,793,487 - 47,793,697UniSTSRGSC3.4
Celera2052,635,559 - 52,635,769UniSTS
RH 3.4 Map20494.82UniSTS
Cytogenetic Map11q11UniSTS
Cytogenetic Map20q13UniSTS
BF403345  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,700,491 - 33,700,645 (+)MAPPERmRatBN7.2
Rnor_6.01134,609,662 - 34,609,815NCBIRnor6.0
Rnor_5.01138,197,409 - 38,197,562UniSTSRnor5.0
RGSC_v3.41134,628,880 - 34,629,033UniSTSRGSC3.4
Celera1134,749,178 - 34,749,331UniSTS
RH 3.4 Map11255.01UniSTS
Cytogenetic Map11q11UniSTS
RH135393  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81147,185,192 - 47,185,394 (+)Marker Load Pipeline
mRatBN7.21133,715,552 - 33,715,755 (+)MAPPERmRatBN7.2
Rnor_6.01134,624,722 - 34,624,924NCBIRnor6.0
Rnor_5.01138,212,469 - 38,212,671UniSTSRnor5.0
RGSC_v3.41134,643,940 - 34,644,142UniSTSRGSC3.4
Celera1134,734,041 - 34,734,243UniSTS
RH 3.4 Map11255.01UniSTS
Cytogenetic Map11q11UniSTS
RH139415  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,788,614 - 33,788,826 (+)MAPPERmRatBN7.2
Rnor_6.01134,739,625 - 34,739,836NCBIRnor6.0
Rnor_5.01138,331,274 - 38,331,485UniSTSRnor5.0
Celera1134,661,601 - 34,661,812UniSTS
Cytogenetic Map11q11UniSTS
AI102584  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,761,635 - 33,761,844 (+)MAPPERmRatBN7.2
Rnor_6.01134,693,577 - 34,693,785NCBIRnor6.0
Rnor_5.01138,284,983 - 38,285,191UniSTSRnor5.0
Celera1134,688,581 - 34,688,789UniSTS
RH 3.4 Map11255.01UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000065600   ⟹   ENSRNOP00000059742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1147,158,792 - 47,258,418 (+)Ensembl
mRatBN7.2 Ensembl1133,688,952 - 33,788,973 (+)Ensembl
Rnor_6.0 Ensembl1134,598,492 - 34,738,791 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105771   ⟹   ENSRNOP00000077352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1147,161,088 - 47,257,478 (+)Ensembl
mRatBN7.2 Ensembl1133,689,876 - 33,788,973 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109810   ⟹   ENSRNOP00000077403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,689,876 - 33,788,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110629   ⟹   ENSRNOP00000090254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,690,630 - 33,788,973 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113628   ⟹   ENSRNOP00000088126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1147,159,568 - 47,258,418 (+)Ensembl
mRatBN7.2 Ensembl1133,689,182 - 33,788,973 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117603   ⟹   ENSRNOP00000096691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,690,630 - 33,788,973 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139699   ⟹   ENSRNOP00000103098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1147,158,792 - 47,184,186 (+)Ensembl
RefSeq Acc Id: NM_001108315   ⟹   NP_001101785
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,797 - 47,258,610 (+)NCBI
mRatBN7.21133,689,142 - 33,788,974 (+)NCBI
Rnor_6.01134,598,324 - 34,739,984 (+)NCBI
Rnor_5.01138,186,073 - 38,331,635 (+)NCBI
RGSC_v3.41134,617,072 - 34,659,043 (+)RGD
Celera1134,661,453 - 34,760,646 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088460   ⟹   XP_038944388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,257,317 (+)NCBI
mRatBN7.21133,689,155 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088461   ⟹   XP_038944389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,258,612 (+)NCBI
mRatBN7.21133,689,155 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088464   ⟹   XP_038944392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,161,367 - 47,257,317 (+)NCBI
mRatBN7.21133,697,556 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088465   ⟹   XP_038944393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,161,367 - 47,257,317 (+)NCBI
mRatBN7.21133,697,556 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088466   ⟹   XP_038944394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,783 - 47,257,317 (+)NCBI
mRatBN7.21133,689,124 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088467   ⟹   XP_038944395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,258,612 (+)NCBI
mRatBN7.21133,689,155 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088471   ⟹   XP_038944399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,183,201 - 47,257,314 (+)NCBI
mRatBN7.21133,713,561 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_039088473   ⟹   XP_038944401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,766 - 47,258,612 (+)NCBI
mRatBN7.21133,689,119 - 33,788,976 (+)NCBI
RefSeq Acc Id: XM_063270615   ⟹   XP_063126685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,257,317 (+)NCBI
RefSeq Acc Id: XM_063270616   ⟹   XP_063126686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,257,317 (+)NCBI
RefSeq Acc Id: XM_063270617   ⟹   XP_063126687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,795 - 47,257,317 (+)NCBI
RefSeq Acc Id: XM_063270619   ⟹   XP_063126689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,814 - 47,257,317 (+)NCBI
RefSeq Acc Id: XM_063270620   ⟹   XP_063126690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,788 - 47,257,318 (+)NCBI
RefSeq Acc Id: XM_063270621   ⟹   XP_063126691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,766 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270622   ⟹   XP_063126692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,876 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270624   ⟹   XP_063126694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,876 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270625   ⟹   XP_063126695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,766 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270626   ⟹   XP_063126696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,876 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270627   ⟹   XP_063126697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,766 - 47,257,314 (+)NCBI
RefSeq Acc Id: XM_063270628   ⟹   XP_063126698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,876 - 47,257,313 (+)NCBI
RefSeq Acc Id: XM_063270629   ⟹   XP_063126699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81147,158,766 - 47,257,313 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101785 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944388 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944389 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944392 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944393 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944394 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944395 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944399 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944401 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126685 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126686 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126687 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126689 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126690 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126691 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126692 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126694 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126695 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126696 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126697 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126698 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3ZSP7 (Get FASTA)   NCBI Sequence Viewer  
  EDL76707 (Get FASTA)   NCBI Sequence Viewer  
  EDL76708 (Get FASTA)   NCBI Sequence Viewer  
  EDL76709 (Get FASTA)   NCBI Sequence Viewer  
  EDL76710 (Get FASTA)   NCBI Sequence Viewer  
  EDL76711 (Get FASTA)   NCBI Sequence Viewer  
  EDL76712 (Get FASTA)   NCBI Sequence Viewer  
  EDL76713 (Get FASTA)   NCBI Sequence Viewer  
  EDL76714 (Get FASTA)   NCBI Sequence Viewer  
  EDL76715 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000059742
  ENSRNOP00000077352
RefSeq Acc Id: NP_001101785   ⟸   NM_001108315
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot),   A0A8L2QUD9 (UniProtKB/TrEMBL),   A6KPW4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000059742   ⟸   ENSRNOT00000065600
RefSeq Acc Id: XP_038944401   ⟸   XM_039088473
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A4G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944394   ⟸   XM_039088466
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AR04 (UniProtKB/TrEMBL),   A6KPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944388   ⟸   XM_039088460
- Peptide Label: isoform X3
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038944395   ⟸   XM_039088467
- Peptide Label: isoform X9
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038944389   ⟸   XM_039088461
- Peptide Label: isoform X5
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038944392   ⟸   XM_039088464
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AR04 (UniProtKB/TrEMBL),   A6KPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944393   ⟸   XM_039088465
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AR04 (UniProtKB/TrEMBL),   A6KPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944399   ⟸   XM_039088471
- Peptide Label: isoform X10
- UniProtKB: A0A8I6A4G2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088126   ⟸   ENSRNOT00000113628
Ensembl Acc Id: ENSRNOP00000077352   ⟸   ENSRNOT00000105771
Ensembl Acc Id: ENSRNOP00000090254   ⟸   ENSRNOT00000110629
Ensembl Acc Id: ENSRNOP00000077403   ⟸   ENSRNOT00000109810
Ensembl Acc Id: ENSRNOP00000096691   ⟸   ENSRNOT00000117603
RefSeq Acc Id: XP_063126691   ⟸   XM_063270621
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A4G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126695   ⟸   XM_063270625
- Peptide Label: isoform X13
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126697   ⟸   XM_063270627
- Peptide Label: isoform X13
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126699   ⟸   XM_063270629
- Peptide Label: isoform X14
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126690   ⟸   XM_063270620
- Peptide Label: isoform X8
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063126685   ⟸   XM_063270615
- Peptide Label: isoform X1
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063126686   ⟸   XM_063270616
- Peptide Label: isoform X2
- UniProtKB: D3ZSP7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063126687   ⟸   XM_063270617
- Peptide Label: isoform X4
- UniProtKB: A0A8I5Y675 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126689   ⟸   XM_063270619
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ABF8 (UniProtKB/TrEMBL),   A6KPW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126692   ⟸   XM_063270622
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A4G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126694   ⟸   XM_063270624
- Peptide Label: isoform X13
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126696   ⟸   XM_063270626
- Peptide Label: isoform X13
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126698   ⟸   XM_063270628
- Peptide Label: isoform X14
- UniProtKB: A6KPW8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103098   ⟸   ENSRNOT00000139699
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSP7-F1-model_v2 AlphaFold D3ZSP7 1-2000 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308654 AgrOrtholog
BioCyc Gene G2FUF-21768 BioCyc
Ensembl Genes ENSRNOG00000001682 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000065600 ENTREZGENE
  ENSRNOT00000105771 ENTREZGENE
Gene3D-CATH 1.10.533.10 UniProtKB/Swiss-Prot
  1.25.40.10 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot
  TTC3/DZIP3-like_helical UniProtKB/Swiss-Prot
  TTC3/DZIP3/RBM44-like_helical UniProtKB/Swiss-Prot
  TTC3/DZIP3_dom UniProtKB/Swiss-Prot
  wHTH_TTC3 UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
NCBI Gene 360702 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TTC3 UniProtKB/Swiss-Prot
  E3 UBIQUITIN-PROTEIN LIGASE TTC3 UniProtKB/Swiss-Prot
Pfam DUF5861 UniProtKB/Swiss-Prot
  TTC3 UniProtKB/Swiss-Prot
  TTC3_9th UniProtKB/Swiss-Prot
  wHTH_TTC3 UniProtKB/Swiss-Prot
  zf-RING_2 UniProtKB/Swiss-Prot
PhenoGen Ttc3 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot
  TPR_REGION UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001682 RatGTEx
SMART RING UniProtKB/Swiss-Prot
  TPR UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF48452 UniProtKB/Swiss-Prot
UniProt A0A8I5Y675 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABF8 ENTREZGENE
  A0A8I6AR04 ENTREZGENE
  A0A8L2QUD9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LEB3_RAT UniProtKB/TrEMBL
  A6KPW4 ENTREZGENE, UniProtKB/TrEMBL
  A6KPW5 ENTREZGENE, UniProtKB/TrEMBL
  A6KPW6 ENTREZGENE, UniProtKB/TrEMBL
  A6KPW8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSP7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ttc3  tetratricopeptide repeat domain 3   Ttc3_predicted  tetratricopeptide repeat domain 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ttc3_predicted  tetratricopeptide repeat domain 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED