Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Crybg2 | Rat | 17beta-estradiol | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of CRYBG2 mRNA | CTD | PMID:30165855 | Crybg2 | Rat | 17beta-estradiol | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of CRYBG2 mRNA | CTD | PMID:36828454 | Crybg2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CRYBG2 mRNA | CTD | PMID:21215274 | Crybg2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Crybg2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CRYBG2 mRNA | CTD | PMID:26377647 | Crybg2 | Rat | 2,4,6-tribromophenol | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | 2,4,6-tribromophenol results in increased expression of CRYBG2 mRNA | CTD | PMID:31675489 | Crybg2 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of and affects the more ... | CTD | PMID:38598786 | Crybg2 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of CRYBG2 protein | CTD | PMID:31675489 | Crybg2 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Crybg2 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of CRYBG2 exon | CTD | PMID:33297965 | Crybg2 | Rat | 5-aza-2'-deoxycytidine | decreases methylation | ISO | Crybg2 (Mus musculus) | 6480464 | Decitabine results in decreased methylation of CRYBG2 gene | CTD | PMID:27923600 | Crybg2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CRYBG2 mRNA | CTD | PMID:24780913 | Crybg2 | Rat | aflatoxin B1 | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of CRYBG2 mRNA | CTD | PMID:19770486 | Crybg2 | Rat | aflatoxin B1 | decreases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of AIM1L exon | CTD | PMID:30157460 | Crybg2 | Rat | aflatoxin B1 | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of CRYBG2 mRNA | CTD | PMID:27153756 | Crybg2 | Rat | aflatoxin B1 | increases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CRYBG2 gene | CTD | PMID:27153756 | Crybg2 | Rat | aldehydo-D-glucose | multiple interactions | ISO | Crybg2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Crybg2 | Rat | all-trans-retinoic acid | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CRYBG2 mRNA | CTD | PMID:23724009 | Crybg2 | Rat | antirheumatic drug | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CRYBG2 mRNA | CTD | PMID:24449571 | Crybg2 | Rat | benzo[a]pyrene | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of CRYBG2 mRNA | CTD | PMID:20064835 | Crybg2 | Rat | benzo[a]pyrene | increases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of AIM1L exon; Benzo(a)pyrene results in increased methylation of AIM1L more ... | CTD | PMID:27901495 | Crybg2 | Rat | benzo[a]pyrene | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CRYBG2 mRNA | CTD | PMID:22316170 | Crybg2 | Rat | benzo[e]pyrene | increases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of AIM1L exon | CTD | PMID:30157460 | Crybg2 | Rat | beta-lapachone | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of CRYBG2 mRNA | CTD | PMID:38218311 | Crybg2 | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Mustard Gas results in increased expression of CRYBG2 mRNA | CTD | PMID:25102026 | Crybg2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of CRYBG2 protein | CTD | PMID:31163220 | Crybg2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of AIM1L mRNA | CTD | PMID:31163220 | Crybg2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CRYBG2 mRNA | CTD | PMID:25181051 | Crybg2 | Rat | bisphenol A | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CRYBG2 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:31675489|PMID:36828454 | Crybg2 | Rat | bisphenol A | decreases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CRYBG2 gene | CTD | PMID:31601247 | Crybg2 | Rat | butanal | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of CRYBG2 mRNA | CTD | PMID:26079696 | Crybg2 | Rat | Butylbenzyl phthalate | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of CRYBG2 mRNA | CTD | PMID:28392331 | Crybg2 | Rat | cadmium dichloride | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of AIM1L mRNA | CTD | PMID:38382870 | Crybg2 | Rat | cantharidin | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | Cantharidin results in increased expression of CRYBG2 mRNA | CTD | PMID:36907384 | Crybg2 | Rat | CGP 52608 | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to AIM1L gene] | CTD | PMID:28238834 | Crybg2 | Rat | chlorpyrifos | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of CRYBG2 mRNA | CTD | PMID:37019170 | Crybg2 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of CRYBG2 mRNA | CTD | PMID:24386269 | Crybg2 | Rat | copper(II) sulfate | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of CRYBG2 mRNA | CTD | PMID:19549813 | Crybg2 | Rat | cyclosporin A | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CRYBG2 mRNA | CTD | PMID:20106945|PMID:25562108 | Crybg2 | Rat | D-glucose | multiple interactions | ISO | Crybg2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Crybg2 | Rat | decabromodiphenyl ether | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of CRYBG2 protein | CTD | PMID:31675489 | Crybg2 | Rat | dicrotophos | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of CRYBG2 mRNA | CTD | PMID:28302478 | Crybg2 | Rat | diquat | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | Diquat results in increased expression of CRYBG2 mRNA | CTD | PMID:36851058 | Crybg2 | Rat | dorsomorphin | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Crybg2 | Rat | elemental selenium | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Selenium results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | elemental selenium | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | entinostat | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | entinostat results in increased expression of CRYBG2 mRNA | CTD | PMID:27188386 | Crybg2 | Rat | ethyl methanesulfonate | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of CRYBG2 mRNA | CTD | PMID:23649840 | Crybg2 | Rat | formaldehyde | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CRYBG2 mRNA | CTD | PMID:23649840 | Crybg2 | Rat | fructose | multiple interactions | ISO | Crybg2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Crybg2 | Rat | furfural | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of CRYBG2 protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Crybg2 | Rat | gallic acid | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Gallic Acid results in increased expression of CRYBG2 mRNA | CTD | PMID:34408198 | Crybg2 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of CRYBG2 mRNA | CTD | PMID:24136188 | Crybg2 | Rat | glucose | multiple interactions | ISO | Crybg2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Crybg2 | Rat | hydroquinone | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | hydroquinone results in increased expression of CRYBG2 mRNA | CTD | PMID:29221148 | Crybg2 | Rat | methapyrilene | increases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of AIM1L exon | CTD | PMID:30157460 | Crybg2 | Rat | methyl methanesulfonate | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of CRYBG2 mRNA | CTD | PMID:23649840 | Crybg2 | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Crybg2 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of CRYBG2 intron | CTD | PMID:27776689 | Crybg2 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CRYBG2 mRNA | CTD | PMID:28943392 | Crybg2 | Rat | N-Nitrosopyrrolidine | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in increased expression of CRYBG2 mRNA | CTD | PMID:32234424 | Crybg2 | Rat | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of CRYBG2 mRNA | CTD | PMID:24136188 | Crybg2 | Rat | O-methyleugenol | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | methyleugenol results in increased expression of CRYBG2 mRNA | CTD | PMID:32234424 | Crybg2 | Rat | okadaic acid | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of CRYBG2 mRNA | CTD | PMID:38832940 | Crybg2 | Rat | pentanal | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | pentanal results in increased expression of CRYBG2 mRNA | CTD | PMID:26079696 | Crybg2 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Crybg2 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of CRYBG2 mRNA | CTD | PMID:37995155 | Crybg2 | Rat | phenobarbital | affects expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of CRYBG2 mRNA | CTD | PMID:19159669 | Crybg2 | Rat | phenylmercury acetate | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Crybg2 | Rat | progesterone | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Progesterone results in increased expression of CRYBG2 mRNA | CTD | PMID:17404688 | Crybg2 | Rat | progesterone | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of CRYBG2 mRNA | CTD | PMID:21540246 | Crybg2 | Rat | propanal | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of CRYBG2 mRNA | CTD | PMID:26079696 | Crybg2 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of AIM1L mRNA | CTD | PMID:28374803 | Crybg2 | Rat | SB 431542 | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Crybg2 | Rat | selenium atom | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Selenium results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | selenium atom | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | silicon dioxide | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of AIM1L mRNA | CTD | PMID:34973136 | Crybg2 | Rat | silver atom | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Silver results in increased expression of CRYBG2 mRNA | CTD | PMID:28959546 | Crybg2 | Rat | silver(0) | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Silver results in increased expression of CRYBG2 mRNA | CTD | PMID:28959546 | Crybg2 | Rat | sodium arsenite | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CRYBG2 mRNA | CTD | PMID:29301061 | Crybg2 | Rat | sodium arsenite | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CRYBG2 mRNA | CTD | PMID:39719251 | Crybg2 | Rat | sodium chloride | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of CRYBG2 protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Crybg2 | Rat | testosterone | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of AIM1L mRNA | CTD | PMID:33359661 | Crybg2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of CRYBG2 mRNA | CTD | PMID:23411599 | Crybg2 | Rat | thioacetamide | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CRYBG2 mRNA | CTD | PMID:28943392 | Crybg2 | Rat | titanium dioxide | increases expression | ISO | Crybg2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CRYBG2 mRNA | CTD | PMID:23557971 | Crybg2 | Rat | titanium dioxide | decreases methylation | ISO | Crybg2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of AIM1L gene | CTD | PMID:35295148 | Crybg2 | Rat | triphenyl phosphate | affects expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CRYBG2 mRNA | CTD | PMID:37042841 | Crybg2 | Rat | urethane | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of CRYBG2 mRNA | CTD | PMID:28818685 | Crybg2 | Rat | valproic acid | affects expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CRYBG2 mRNA | CTD | PMID:25979313 | Crybg2 | Rat | valproic acid | increases methylation | ISO | CRYBG2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CRYBG2 gene | CTD | PMID:29154799 | Crybg2 | Rat | valproic acid | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CRYBG2 mRNA | CTD | PMID:23179753|PMID:23527032|PMID:26272509|PMID:28001369 | Crybg2 | Rat | valproic acid | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Crybg2 | Rat | vitamin E | increases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | vitamin E | multiple interactions | ISO | CRYBG2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA | CTD | PMID:19244175 | Crybg2 | Rat | zearalenone | decreases expression | ISO | CRYBG2 (Homo sapiens) | 6480464 | Zearalenone results in decreased expression of CRYBG2 mRNA | CTD | PMID:36828454 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















