Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Drc8 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Efcab2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EFCAB2 mRNA | CTD | PMID:36331819 | Drc8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Efcab2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of EFCAB2 mRNA | CTD | PMID:21570461 | Drc8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of EFCAB2 mRNA | CTD | PMID:33387578 | Drc8 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of EFCAB2 mRNA | CTD | PMID:32071231 | Drc8 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of EFCAB2 mRNA | CTD | PMID:24780913 | Drc8 | Rat | aflatoxin M1 | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of DRC8 mRNA | CTD | PMID:30928695 | Drc8 | Rat | all-trans-retinoic acid | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of DRC8 mRNA | CTD | PMID:23724009 | Drc8 | Rat | all-trans-retinoic acid | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DRC8 mRNA | CTD | PMID:33167477 | Drc8 | Rat | antirheumatic drug | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DRC8 mRNA | CTD | PMID:24449571 | Drc8 | Rat | aristolochic acid A | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DRC8 mRNA | CTD | PMID:33212167 | Drc8 | Rat | arsane | affects expression | ISO | DRC8 (Homo sapiens) | 6480464 | Arsenic affects the expression of DRC8 mRNA | CTD | PMID:18414638 | Drc8 | Rat | arsane | affects methylation | ISO | DRC8 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DRC8 gene | CTD | PMID:25304211 | Drc8 | Rat | arsenic atom | affects expression | ISO | DRC8 (Homo sapiens) | 6480464 | Arsenic affects the expression of DRC8 mRNA | CTD | PMID:18414638 | Drc8 | Rat | arsenic atom | affects methylation | ISO | DRC8 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DRC8 gene | CTD | PMID:25304211 | Drc8 | Rat | belinostat | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | belinostat results in decreased expression of DRC8 mRNA | CTD | PMID:27188386 | Drc8 | Rat | benzo[a]pyrene | decreases expression | ISO | Efcab2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of EFCAB2 mRNA | CTD | PMID:22228805 | Drc8 | Rat | benzo[a]pyrene | affects methylation | ISO | DRC8 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DRC8 promoter | CTD | PMID:27901495 | Drc8 | Rat | benzo[a]pyrene | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of DRC8 mRNA | CTD | PMID:20106945|PMID:21632981 | Drc8 | Rat | bisphenol A | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of EFCAB2 mRNA | CTD | PMID:26063408|PMID:32071231 | Drc8 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EFCAB2 mRNA | CTD | PMID:25181051|PMID:34947998 | Drc8 | Rat | Bufotalin | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | bufotalin results in decreased expression of EFCAB2 mRNA | CTD | PMID:39904859 | Drc8 | Rat | butanal | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of DRC8 mRNA | CTD | PMID:26079696 | Drc8 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Efcab2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of EFCAB2 intron | CTD | PMID:28392331 | Drc8 | Rat | cadmium atom | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DRC8 more ... | CTD | PMID:35301059 | Drc8 | Rat | cadmium dichloride | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DRC8 more ... | CTD | PMID:35301059 | Drc8 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of EFCAB2 mRNA | CTD | PMID:26033743 | Drc8 | Rat | copper atom | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DRC8 mRNA | CTD | PMID:20971185 | Drc8 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of EFCAB2 mRNA | CTD | PMID:26033743 | Drc8 | Rat | copper(0) | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DRC8 mRNA | CTD | PMID:20971185 | Drc8 | Rat | cyclosporin A | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DRC8 mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Drc8 | Rat | dorsomorphin | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Drc8 | Rat | doxorubicin | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DRC8 mRNA | CTD | PMID:29803840 | Drc8 | Rat | ethanol | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | Ethanol results in increased expression of EFCAB2 mRNA | CTD | PMID:30319688 | Drc8 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of EFCAB2 mRNA | CTD | PMID:30307764 | Drc8 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of EFCAB2 mRNA | CTD | PMID:24793618 | Drc8 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of EFCAB2 mRNA | CTD | PMID:33387578 | Drc8 | Rat | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of EFCAB2 mRNA | CTD | PMID:22641619 | Drc8 | Rat | methyl methanesulfonate | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DRC8 mRNA | CTD | PMID:23649840 | Drc8 | Rat | okadaic acid | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of DRC8 mRNA | CTD | PMID:38832940 | Drc8 | Rat | ozone | multiple interactions | ISO | Efcab2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Drc8 | Rat | paracetamol | affects expression | ISO | Efcab2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of EFCAB2 mRNA | CTD | PMID:17562736 | Drc8 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of EFCAB2 mRNA | CTD | PMID:33387578 | Drc8 | Rat | pentanal | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | pentanal results in decreased expression of DRC8 mRNA | CTD | PMID:26079696 | Drc8 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in increased expression of DRC8 mRNA | CTD | PMID:25812627 | Drc8 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of EFCAB2 mRNA | CTD | PMID:37995155 | Drc8 | Rat | perfluorononanoic acid | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of DRC8 mRNA | CTD | PMID:25812627 | Drc8 | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of DRC8 mRNA | CTD | PMID:25812627 | Drc8 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Efcab2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EFCAB2 mRNA | CTD | PMID:36331819 | Drc8 | Rat | propanal | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of DRC8 mRNA | CTD | PMID:26079696 | Drc8 | Rat | resveratrol | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of DRC8 mRNA | CTD | PMID:23557933 | Drc8 | Rat | SB 431542 | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Drc8 | Rat | sodium arsenite | increases expression | ISO | DRC8 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DRC8 mRNA | CTD | PMID:38568856 | Drc8 | Rat | sodium arsenite | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DRC8 mRNA | CTD | PMID:34032870 | Drc8 | Rat | sunitinib | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DRC8 mRNA | CTD | PMID:31533062 | Drc8 | Rat | thalidomide | decreases expression | ISO | Efcab2 (Mus musculus) | 6480464 | Thalidomide results in decreased expression of EFCAB2 mRNA | CTD | PMID:26217789 | Drc8 | Rat | titanium dioxide | decreases expression | ISO | Efcab2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of EFCAB2 mRNA | CTD | PMID:23557971 | Drc8 | Rat | titanium dioxide | decreases methylation | ISO | Efcab2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of EFCAB2 gene | CTD | PMID:35295148 | Drc8 | Rat | titanium dioxide | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of EFCAB2 mRNA | CTD | PMID:29264374 | Drc8 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of EFCAB2 mRNA | CTD | PMID:33387578 | Drc8 | Rat | triptonide | increases expression | ISO | Efcab2 (Mus musculus) | 6480464 | triptonide results in increased expression of EFCAB2 mRNA | CTD | PMID:33045310 | Drc8 | Rat | trovafloxacin | decreases expression | ISO | Efcab2 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of EFCAB2 mRNA | CTD | PMID:35537566 | Drc8 | Rat | valproic acid | affects expression | ISO | DRC8 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DRC8 mRNA | CTD | PMID:25979313 | Drc8 | Rat | valproic acid | multiple interactions | ISO | DRC8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Drc8 | Rat | valproic acid | decreases expression | ISO | DRC8 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DRC8 mRNA | CTD | PMID:23179753|PMID:26272509|PMID:27188386 | Drc8 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of EFCAB2 mRNA | CTD | PMID:20566332 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















