Drc8 (dynein regulatory complex subunit 8) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Drc8 (dynein regulatory complex subunit 8) Rattus norvegicus
Analyze
Symbol: Drc8 (Ensembl: Efcab2)
Name: dynein regulatory complex subunit 8 (Ensembl:EF-hand calcium binding domain 2)
RGD ID: 1308593
Description: Predicted to enable calcium ion binding activity. Predicted to be located in organelle. Predicted to be active in sperm principal piece. Orthologous to human EFCAB2 (EF-hand calcium binding domain 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dynein regulatory complex protein 8; EF-hand calcium binding domain 2; EF-hand calcium-binding domain-containing protein 2; EF-hand calcium-binding domain-containing protein 2-like; Efcab2; LOC102550369; LOC289280; RGD1308593; similar to RIKEN cDNA 1700073K01
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,683,182 - 92,769,939 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1392,684,086 - 92,782,558 (+)EnsemblGRCr8
mRatBN7.21390,152,002 - 90,237,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1390,152,185 - 90,238,218 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1392,657,438 - 92,743,164 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01394,057,585 - 94,143,324 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,239,272 - 91,324,914 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,303,578 - 96,414,404 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,303,703 - 96,414,404 (+)Ensemblrn6Rnor6.0
Rnor_5.013100,743,957 - 100,849,978 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41394,052,873 - 94,138,884 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1389,710,327 - 89,795,437 (+)NCBICelera
RGSC_v3.11394,241,888 - 94,325,858 (+)NCBI
Cytogenetic Map13q25-q26NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Drc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,683,182 - 92,769,939 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1392,684,086 - 92,782,558 (+)EnsemblGRCr8
mRatBN7.21390,152,002 - 90,237,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1390,152,185 - 90,238,218 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1392,657,438 - 92,743,164 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01394,057,585 - 94,143,324 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,239,272 - 91,324,914 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,303,578 - 96,414,404 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,303,703 - 96,414,404 (+)Ensemblrn6Rnor6.0
Rnor_5.013100,743,957 - 100,849,978 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41394,052,873 - 94,138,884 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1389,710,327 - 89,795,437 (+)NCBICelera
RGSC_v3.11394,241,888 - 94,325,858 (+)NCBI
Cytogenetic Map13q25-q26NCBI
DRC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381244,969,682 - 245,125,229 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1244,969,682 - 245,127,164 (+)Ensemblhg38GRCh38
GRCh371245,132,984 - 245,288,530 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,200,315 - 243,317,761 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1218,422,357 - 218,577,396 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1215,516,388 - 215,671,647 (+)NCBIHuRef
CHM1_11246,405,474 - 246,560,855 (+)NCBICHM1_1
T2T-CHM13v2.01244,386,344 - 244,542,663 (+)NCBIT2T-CHM13v2.0
Efcab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,233,583 - 178,312,078 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,233,650 - 178,312,078 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381178,406,018 - 178,484,513 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,406,085 - 178,484,513 (+)Ensemblmm10GRCm38
MGSCv371180,336,012 - 180,413,381 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361180,242,556 - 180,319,925 (+)NCBIMGSCv36mm8
Celera1185,465,850 - 185,542,138 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map183.16NCBI
Efcab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554068,089,232 - 8,239,230 (+)Ensembl
ChiLan1.0NW_0049554068,115,813 - 8,239,352 (+)NCBIChiLan1.0ChiLan1.0
EFCAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214,025,029 - 4,181,702 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114,235,100 - 4,405,397 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01220,567,609 - 220,731,339 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11225,948,112 - 226,105,544 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1225,948,238 - 226,102,223 (+)EnsemblpanPan2panpan1.1
EFCAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1735,917,156 - 36,038,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl735,949,240 - 36,038,821 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha735,390,801 - 35,512,461 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0735,746,266 - 35,868,224 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl735,745,980 - 35,868,221 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1735,581,759 - 35,703,560 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0735,596,750 - 35,718,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0735,862,310 - 35,984,137 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Efcab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934448,850,314 - 48,948,695 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365265,798,659 - 5,918,007 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365265,799,212 - 5,877,183 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFCAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1017,628,396 - 17,656,201 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11017,558,224 - 17,655,269 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21020,041,080 - 20,137,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DRC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12581,995,735 - 82,157,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605584,224,079 - 84,387,753 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efcab2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477114,541,405 - 14,609,155 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477114,543,337 - 14,652,003 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Efcab2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11056,748,710 - 56,831,974 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Drc8
633 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:426
Count of miRNA genes:249
Interacting mature miRNAs:293
Transcripts:ENSRNOT00000029723
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH141538  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,199,210 - 90,199,392 (+)MAPPERmRatBN7.2
Rnor_6.01396,350,383 - 96,350,564NCBIRnor6.0
Rnor_5.013100,790,507 - 100,790,688UniSTSRnor5.0
RGSC_v3.41394,100,177 - 94,100,358UniSTSRGSC3.4
Celera1389,756,716 - 89,756,897UniSTS
RH 3.4 Map13609.4UniSTS
Cytogenetic Map13q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001105977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000029723   ⟹   ENSRNOP00000037547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,212 - 92,768,978 (+)Ensembl
mRatBN7.2 Ensembl1390,152,185 - 90,237,918 (+)Ensembl
Rnor_6.0 Ensembl1396,303,825 - 96,414,404 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084718   ⟹   ENSRNOP00000074977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,214 - 92,768,108 (+)Ensembl
mRatBN7.2 Ensembl1390,152,185 - 90,238,218 (+)Ensembl
Rnor_6.0 Ensembl1396,303,703 - 96,412,494 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109721   ⟹   ENSRNOP00000084748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,095 - 92,768,978 (+)Ensembl
mRatBN7.2 Ensembl1390,192,097 - 90,237,918 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135019   ⟹   ENSRNOP00000107795
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,408 - 92,778,034 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135158   ⟹   ENSRNOP00000101818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,408 - 92,778,034 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141512   ⟹   ENSRNOP00000111609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,212 - 92,782,558 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000144005   ⟹   ENSRNOP00000105282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,353 - 92,768,978 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147056   ⟹   ENSRNOP00000106408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,725,240 - 92,768,108 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155864   ⟹   ENSRNOP00000099910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,086 - 92,768,978 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158471   ⟹   ENSRNOP00000102552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,684,087 - 92,768,978 (+)Ensembl
RefSeq Acc Id: NM_001105977   ⟹   NP_001099447
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,684,212 - 92,769,939 (+)NCBI
mRatBN7.21390,152,185 - 90,237,918 (+)NCBI
Rnor_6.01396,303,825 - 96,414,404 (+)NCBI
Rnor_5.013100,743,957 - 100,849,978 (+)NCBI
RGSC_v3.41394,052,873 - 94,138,884 (+)RGD
Celera1389,710,327 - 89,795,437 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250319   ⟹   XP_006250381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,013 - 90,236,215 (+)NCBI
Rnor_6.01396,303,578 - 96,412,701 (+)NCBI
Rnor_5.013100,743,957 - 100,849,978 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090534   ⟹   XP_038946462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,007 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_039090535   ⟹   XP_038946463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,002 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_039090537   ⟹   XP_038946465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,008 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_039090538   ⟹   XP_038946466
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,002 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_039090543   ⟹   XP_038946471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,764,144 (+)NCBI
mRatBN7.21390,152,007 - 90,235,833 (+)NCBI
RefSeq Acc Id: XM_039090544   ⟹   XP_038946472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,002 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_039090545   ⟹   XP_038946473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
mRatBN7.21390,152,008 - 90,231,545 (+)NCBI
RefSeq Acc Id: XM_039090547   ⟹   XP_038946475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
mRatBN7.21390,152,010 - 90,231,545 (+)NCBI
RefSeq Acc Id: XM_039090549   ⟹   XP_038946477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
mRatBN7.21390,152,006 - 90,236,215 (+)NCBI
RefSeq Acc Id: XM_063272139   ⟹   XP_063128209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272140   ⟹   XP_063128210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272141   ⟹   XP_063128211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272142   ⟹   XP_063128212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272143   ⟹   XP_063128213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,764,158 (+)NCBI
RefSeq Acc Id: XM_063272144   ⟹   XP_063128214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272146   ⟹   XP_063128216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,056 (+)NCBI
RefSeq Acc Id: XM_063272147   ⟹   XP_063128217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272148   ⟹   XP_063128218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272149   ⟹   XP_063128219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272150   ⟹   XP_063128220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272151   ⟹   XP_063128221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,056 (+)NCBI
RefSeq Acc Id: XM_063272152   ⟹   XP_063128222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,730,745 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272153   ⟹   XP_063128223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272154   ⟹   XP_063128224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272155   ⟹   XP_063128225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272156   ⟹   XP_063128226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272157   ⟹   XP_063128227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272158   ⟹   XP_063128228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272159   ⟹   XP_063128229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272160   ⟹   XP_063128230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
RefSeq Acc Id: XM_063272161   ⟹   XP_063128231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272162   ⟹   XP_063128232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,768,236 (+)NCBI
RefSeq Acc Id: XM_063272163   ⟹   XP_063128233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,683,182 - 92,763,570 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099447 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430809 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430810 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430811 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430812 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430813 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430814 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250381 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946462 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946463 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946465 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946466 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946471 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946472 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946473 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946475 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946477 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128209 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128210 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128211 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128212 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128213 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128214 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128216 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128217 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128218 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128219 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128220 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128221 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128222 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128223 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128224 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128225 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128226 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128227 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128228 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128229 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128230 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128231 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128232 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128233 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94803 (Get FASTA)   NCBI Sequence Viewer  
  EDL94804 (Get FASTA)   NCBI Sequence Viewer  
  EDL94805 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000037547.5
  ENSRNOP00000074977.3
  ENSRNOP00000084748
  ENSRNOP00000084748.2
  ENSRNOP00000099910
  ENSRNOP00000099910.1
  ENSRNOP00000101818.1
  ENSRNOP00000102552.1
  ENSRNOP00000105282.1
  ENSRNOP00000106408
  ENSRNOP00000106408.1
  ENSRNOP00000107795.1
  ENSRNOP00000111609.1
RefSeq Acc Id: NP_001099447   ⟸   NM_001105977
- UniProtKB: D3ZXJ2 (UniProtKB/TrEMBL),   A6JGE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250381   ⟸   XM_006250319
- Peptide Label: isoform X15
- UniProtKB: A0A0G2K9F5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074977   ⟸   ENSRNOT00000084718
Ensembl Acc Id: ENSRNOP00000037547   ⟸   ENSRNOT00000029723
RefSeq Acc Id: XP_038946472   ⟸   XM_039090544
- Peptide Label: isoform X23
RefSeq Acc Id: XP_038946466   ⟸   XM_039090538
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038946463   ⟸   XM_039090535
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038946477   ⟸   XM_039090549
- Peptide Label: isoform X28
RefSeq Acc Id: XP_038946462   ⟸   XM_039090534
- Peptide Label: isoform X11
- UniProtKB: A0A0G2K9F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946471   ⟸   XM_039090543
- Peptide Label: isoform X22
RefSeq Acc Id: XP_038946465   ⟸   XM_039090537
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038946473   ⟸   XM_039090545
- Peptide Label: isoform X24
RefSeq Acc Id: XP_038946475   ⟸   XM_039090547
- Peptide Label: isoform X27
Ensembl Acc Id: ENSRNOP00000084748   ⟸   ENSRNOT00000109721
RefSeq Acc Id: XP_063128225   ⟸   XM_063272155
- Peptide Label: isoform X19
RefSeq Acc Id: XP_063128228   ⟸   XM_063272158
- Peptide Label: isoform X25
RefSeq Acc Id: XP_063128232   ⟸   XM_063272162
- Peptide Label: isoform X31
RefSeq Acc Id: XP_063128226   ⟸   XM_063272156
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063128224   ⟸   XM_063272154
- Peptide Label: isoform X18
RefSeq Acc Id: XP_063128231   ⟸   XM_063272161
- Peptide Label: isoform X30
RefSeq Acc Id: XP_063128217   ⟸   XM_063272147
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063128220   ⟸   XM_063272150
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063128227   ⟸   XM_063272157
- Peptide Label: isoform X21
RefSeq Acc Id: XP_063128233   ⟸   XM_063272163
- Peptide Label: isoform X32
RefSeq Acc Id: XP_063128223   ⟸   XM_063272153
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063128218   ⟸   XM_063272148
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063128229   ⟸   XM_063272159
- Peptide Label: isoform X26
RefSeq Acc Id: XP_063128230   ⟸   XM_063272160
- Peptide Label: isoform X29
RefSeq Acc Id: XP_063128212   ⟸   XM_063272142
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063128210   ⟸   XM_063272140
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZXW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128211   ⟸   XM_063272141
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZXW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128222   ⟸   XM_063272152
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063128216   ⟸   XM_063272146
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063128221   ⟸   XM_063272151
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063128213   ⟸   XM_063272143
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063128209   ⟸   XM_063272139
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128214   ⟸   XM_063272144
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063128219   ⟸   XM_063272149
- Peptide Label: isoform X9
Ensembl Acc Id: ENSRNOP00000111609   ⟸   ENSRNOT00000141512
Ensembl Acc Id: ENSRNOP00000105282   ⟸   ENSRNOT00000144005
Ensembl Acc Id: ENSRNOP00000107795   ⟸   ENSRNOT00000135019
Ensembl Acc Id: ENSRNOP00000099910   ⟸   ENSRNOT00000155864
Ensembl Acc Id: ENSRNOP00000102552   ⟸   ENSRNOT00000158471
Ensembl Acc Id: ENSRNOP00000101818   ⟸   ENSRNOT00000135158
Ensembl Acc Id: ENSRNOP00000106408   ⟸   ENSRNOT00000147056
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9F5-F1-model_v2 AlphaFold A0A0G2K9F5 1-164 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699060
Promoter ID:EPDNEW_R9575
Type:single initiation site
Name:Efcab2_1
Description:EF-hand calcium binding domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01396,303,630 - 96,303,690EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308593 AgrOrtholog
BioCyc Gene G2FUF-17170 BioCyc
Ensembl Genes ENSRNOG00000042201 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029723.6 UniProtKB/TrEMBL
  ENSRNOT00000084718.3 UniProtKB/TrEMBL
  ENSRNOT00000109721 ENTREZGENE
  ENSRNOT00000109721.2 UniProtKB/TrEMBL
  ENSRNOT00000135019.1 UniProtKB/TrEMBL
  ENSRNOT00000135158.1 UniProtKB/TrEMBL
  ENSRNOT00000141512.1 UniProtKB/TrEMBL
  ENSRNOT00000144005.1 UniProtKB/TrEMBL
  ENSRNOT00000147056 ENTREZGENE
  ENSRNOT00000147056.1 UniProtKB/TrEMBL
  ENSRNOT00000155864 ENTREZGENE
  ENSRNOT00000155864.1 UniProtKB/TrEMBL
  ENSRNOT00000158471.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-like_dom UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
KEGG Report rno:289280 UniProtKB/TrEMBL
NCBI Gene 289280 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX PROTEIN 8 UniProtKB/TrEMBL
  DYNEIN REGULATORY COMPLEX PROTEIN 8 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
PhenoGen Drc8 PhenoGen
PROSITE EF_HAND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042201 RatGTEx
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2K9F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXW0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L855_RAT UniProtKB/TrEMBL
  A0ABK0L9W3_RAT UniProtKB/TrEMBL
  A0ABK0LE34_RAT UniProtKB/TrEMBL
  A0ABK0LI01_RAT UniProtKB/TrEMBL
  A0ABK0LLG6_RAT UniProtKB/TrEMBL
  A0ABK0LUB8_RAT UniProtKB/TrEMBL
  A0ABK0M0N3_RAT UniProtKB/TrEMBL
  A6JGE7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZXJ2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Drc8  dynein regulatory complex subunit 8  Efcab2  EF-hand calcium binding domain 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Efcab2  EF-hand calcium binding domain 2  LOC102550369  EF-hand calcium-binding domain-containing protein 2-like  Data merged from RGD:7503858 737654 PROVISIONAL
2013-12-17 LOC102550369  EF-hand calcium-binding domain-containing protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Efcab2  EF-hand calcium binding domain 2   Efcab2_predicted  EF-hand calcium binding domain 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Efcab2_predicted  EF-hand calcium binding domain 2 (predicted)  RGD1308593_predicted  similar to RIKEN cDNA 1700073K01 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1308593_predicted  similar to RIKEN cDNA 1700073K01 (predicted)  LOC289280_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289280_predicted  similar to RIKEN cDNA 1700073K01 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL