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Gene: Meis3 (Meis homeobox 3) Rattus norvegicus

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Symbol:

Meis3

Name:

Meis homeobox 3

RGD ID:

1308532

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including angiogenesis; embryonic pattern specification; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of apoptotic signaling pathway and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in nucleus. Orthologous to several human genes including MEIS3 (Meis homeobox 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

homeobox protein Meis3; LOC361514; Meis1, myeloid ecotropic viral integration site 1 homolog 3; Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse); Mrg2; myeloid ecotropic viral integration site-related gene 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MEIS3 (Meis homeobox 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Meis3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Meis3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MEIS3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MEIS3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Meis3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MEIS3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MEIS3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Meis3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Meis3 (Meis homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MEIS3P1 (Meis homeobox 3 pseudogene 1)	HGNC	Panther
Homo sapiens (human):	MEIS3P2 (Meis homeobox 3 pseudogene 2)	HGNC	Panther
Homo sapiens (human):	TOM1L2 (target of myb1 like 2 membrane trafficking protein)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	MEIS3 (Meis homeobox 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MEIS3 (Meis homeobox 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Meis3 (Meis homeobox 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MEIS3P1 (Meis homeobox 3 pseudogene 1)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Homo sapiens (human):	MEIS3P1 (Meis homeobox 3 pseudogene 1)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Homo sapiens (human):	MEIS3P2 (Meis homeobox 3 pseudogene 2)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MEIS3P2 (Meis homeobox 3 pseudogene 2)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	meis3 (myeloid ecotropic viral integration site 3)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	meis3 (myeloid ecotropic viral integration site 3)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	CUP9	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	CUP9	Alliance	DIOPT (OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	hth	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	hth	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-62	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TOS8	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	meis3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	85,986,602 - 86,000,873 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	85,990,050 - 86,000,873 (+)	Ensembl				GRCr8
mRatBN7.2	1	76,861,267 - 76,872,691 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	76,861,924 - 76,872,691 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	82,235,960 - 82,246,772 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	90,799,986 - 90,810,801 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	83,991,059 - 84,001,871 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,065,617 - 78,079,698 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,068,931 - 78,079,862 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	79,335,318 - 79,346,214 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	76,513,672 - 76,524,431 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	71,352,130 - 71,362,888 (+)	NCBI		Celera
RGSC_v3.1	1	76,579,037 - 76,602,545 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amphetamine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

chlorpyrifos (ISO)

choline (ISO)

clofibrate (ISO)

copper atom (EXP)

copper(0) (EXP)

deoxynivalenol (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

endosulfan (EXP)

fipronil (EXP)

folic acid (ISO)

gallic acid (ISO)

indometacin (ISO)

L-methionine (ISO)

maneb (ISO)

methapyrilene (ISO)

niclosamide (ISO)

paracetamol (EXP)

paraquat (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triclosan (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IBA)

animal organ morphogenesis (IBA)

brain development (IBA)

embryonic pattern specification (IBA)

eye development (IBA)

hemopoiesis (IBA)

negative regulation of apoptotic signaling pathway (ISO)

positive regulation of cell population proliferation (IBA)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of transcription by RNA polymerase II (IBA,IEA)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

chromatin binding (IEA,ISO)

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IBA,IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17178831	PMID:21059917

Genomics

Comparative Map Data

Meis3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	85,986,602 - 86,000,873 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	85,990,050 - 86,000,873 (+)	Ensembl				GRCr8
mRatBN7.2	1	76,861,267 - 76,872,691 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	76,861,924 - 76,872,691 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	82,235,960 - 82,246,772 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	90,799,986 - 90,810,801 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	83,991,059 - 84,001,871 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,065,617 - 78,079,698 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,068,931 - 78,079,862 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	79,335,318 - 79,346,214 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	76,513,672 - 76,524,431 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	71,352,130 - 71,362,888 (+)	NCBI		Celera
RGSC_v3.1	1	76,579,037 - 76,602,545 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

MEIS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	47,403,124 - 47,422,233 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	47,403,124 - 47,419,530 (-)	Ensembl			hg38	GRCh38
GRCh37	19	47,906,381 - 47,925,490 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	52,598,193 - 52,614,597 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	44,710,265 - 44,726,668 (-)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	44,330,771 - 44,346,745 (-)	NCBI		HuRef
CHM1_1	19	47,908,568 - 47,924,966 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	50,228,571 - 50,253,087 (-)	NCBI		T2T-CHM13v2.0

Meis3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	15,908,684 - 15,920,435 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	15,909,015 - 15,920,429 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	16,174,012 - 16,186,510 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	16,175,090 - 16,186,504 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	16,760,729 - 16,771,853 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	15,333,952 - 15,345,019 (+)	NCBI		MGSCv36	mm8
Celera	7	14,736,434 - 14,737,446 (-)	NCBI		Celera
Cytogenetic Map	7	A2	NCBI
cM Map	7	8.76	NCBI

Meis3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955574	1,273,321 - 1,282,455 (-)	Ensembl
ChiLan1.0	NW_004955574	1,273,321 - 1,282,454 (-)	NCBI	ChiLan1.0	ChiLan1.0

MEIS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	53,550,545 - 53,573,384 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	55,420,554 - 55,443,389 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	44,391,523 - 44,414,259 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	53,048,140 - 53,063,247 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	53,048,140 - 53,063,247 (-)	Ensembl			panPan2	panpan1.1

MEIS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	108,591,759 - 108,602,635 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	108,591,589 - 108,604,040 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	108,072,767 - 108,084,314 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	109,117,119 - 109,125,833 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	109,116,601 - 109,126,240 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	108,784,256 - 108,795,805 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	108,428,779 - 108,440,343 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	109,297,342 - 109,308,902 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Meis3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	19,477,686 - 19,487,633 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	1,095,772 - 1,105,808 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	1,095,815 - 1,105,751 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MEIS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	53,175,928 - 53,188,406 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	53,175,920 - 53,188,455 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	48,817,091 - 48,842,383 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MEIS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	40,730,208 - 40,747,086 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	40,729,230 - 40,746,741 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	20,464,484 - 20,481,274 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Meis3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	6,369,259 - 6,377,268 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624832	6,369,248 - 6,379,754 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Meis3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	172,894,715 - 172,906,074 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Meis3
117 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	612
Count of miRNA genes:	153
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000039538, ENSRNOT00000068406
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Markers in Region

AI573393

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	86,000,708 - 86,000,822 (+)	Marker Load Pipeline
mRatBN7.2	1	76,872,526 - 76,872,639 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	78,079,534 - 78,079,646	NCBI	Rnor6.0
Rnor_5.0	1	79,346,050 - 79,346,162	UniSTS	Rnor5.0
RGSC_v3.4	1	76,524,276 - 76,524,388	UniSTS	RGSC3.4
Celera	1	71,362,733 - 71,362,845	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	160	91	90	59	92	59	6	356	192	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC160854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000039538 ⟹ ENSRNOP00000033135

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	85,990,350 - 85,998,354 (+)	Ensembl
mRatBN7.2 Ensembl	1	76,861,924 - 76,872,682 (+)	Ensembl
Rnor_6.0 Ensembl	1	78,068,931 - 78,079,689 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000068406 ⟹ ENSRNOP00000063858

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	85,990,050 - 86,000,873 (+)	Ensembl
mRatBN7.2 Ensembl	1	76,861,924 - 76,872,682 (+)	Ensembl
Rnor_6.0 Ensembl	1	78,069,193 - 78,079,862 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118727 ⟹ ENSRNOP00000096875

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	85,990,050 - 86,000,873 (+)	Ensembl
mRatBN7.2 Ensembl	1	76,863,372 - 76,872,691 (+)	Ensembl

RefSeq Acc Id:

NM_001108472 ⟹ NP_001101942

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,050 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,861,868 - 76,872,691 (+)	NCBI
Rnor_6.0	1	78,068,931 - 78,079,689 (+)	NCBI
Rnor_5.0	1	79,335,318 - 79,346,214 (+)	NCBI
RGSC_v3.4	1	76,513,672 - 76,524,431 (+)	RGD
Celera	1	71,352,130 - 71,362,888 (+)	RGD

Sequence:

show sequence

CAAGACCCCGCGAATCTGACATACAAAGGCCAAAGCCGGGCCCGTGTGAGCCCAGGAGCCGCCG
CCACCCTCGGCCGCGATCCGCGGGTCTTGGCCACTCGGAGACCCCGGCACCCGGCGGGGACCTC
GGGGACCTCCGGCCGCGATGAGCCCCAGGCCGTGACCTCCCGAGCCCAGGACGCGCGGCGCCGG
CTCATGGCCCGGAGGTATGAGGAGCCGCGCCACTACCCCGGCATTACCGAGCACACGGCAGCCC
TGGCCAGTTTTCCAGAGGCAGCACCTTCAGTACCTCGAGCTCCTGGGCCCTATGGCCCACACCG
GCCGCCCCAACCCCAAGGTCCAGGCTTGGACAGCGATAGCTTGAAGAGAGAGAAGGATGACATC
TATGGACACCCCCTCTTCCCACTCTTGGCCCTGGTCTTTGAGAAGTGTGAGCTGGCTACATGCT
CGCCCCGTGATGGGGCCTCGGCTGGGCTGGGTTCACCCCCAGGTGGTGACGTCTGCTCCTCTGA
CTCCTTCAATGAGGATATTGCTGCCTTTGCTAAGCAGATCCGCTCCGAGAGGCCGCTGTTCTCT
TCCAACCCGGAGCTGGACAACCTGATGGTCCAGGCCATCCAGGTACTCCGGTTCCACCTGCTGG
AGCTGGAGAAGGTCCACGACCTGTGCGACAACTTCTGTCACCGCTACATCACCTGCCTCAAGGG
GAAGATGCCCATAGACCTGGTGATCGAGGATCGGGATGGTGGTTGCAGGGAGGACCTTGAGGAC
TACGCAGCCTCCTGCCCCAGCCTCCCAGACCAGAATACTACATGGATCAGAGACCATGAGGACA
GTGGGTCTGTACATTTGGGGACCCCAGGTCCATCCAGCGGAGGCCTGGCCTCCCAGAGCGGGGA
CAACTCAAGTGACCAAGGAGATGGGCTGGACACCAGCGTGGCCTCTCCCAGCTCCGCAGGAGAG
GATGAGGACCTGGACCTGGAGCGCAGACGGAACAAGAAGAGGGGGATCTTCCCCAAAGTGGCCA
CCAACATCATGAGGGCCTGGTTGTTCCAGCATCTCTCGCACCCGTACCCCTCAGAAGAGCAAAA
GAAACAGCTGGCCCAGGACACCGGGCTCACCATTCTGCAGGTGAACAACTGGTTTATTAATGCC
CGGAGACGGATAGTGCAGCCCATGATTGACCAGTCTAATCGTACAGGGCAGGGTGCATCTTTCA
ACCCTGAGGGCCAGTCCATGGCAGGCTACACAGAGACTCAACCACATGTGACAGTCAGGACGCC
AGGATCAATGGGGATGAATCTGAACTTAGAAGGAGAATGGCATTACCTATAGAGGTTGGGGTCA
AAAGGAGGGCCCCAGCCTCTGACTATGACCACCAGCCTTGCACCTAATTGGTCCCTGCTGGTCC
CTGGGCTTCAGGACTTCACCTCCAAAGCTCCCACCCCATTCAACGCCTACCTCCCTGGGGCCCC
CAGAGGCTTGAGGACCCAGAGCCCACTTGAGGGTTTCTCAAGGGCAAAGACAAAGCCTCAAGGT
CCTGCACCCTTCTTCTGCCCTCCCCTTTGCCCAGGACCTGAGCTGAGAACTGGGCCAAGGTCTG
AAGAAGATGGTGGCTGGGGCCCCAATCCAGGACAGAGAAGAGACTGGGGTTGGGCAAGGATGGG
CAAGGAAGGAGGGTCAGCTGGATCCAATGTTTGGGAGAATCCTTCATCTTCCTGCTCTCTGCCT
CTCTCACCTCCCTTCTCTGACATTCTTCTACCTTTCCTTTTTTTAATGATAAAGTCTTAAAAGT
GC

hide sequence

RefSeq Acc Id:

NM_001399601 ⟹ NP_001386530

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,341 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,159 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

NM_001399602 ⟹ NP_001386531

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,341 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,159 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_006228351 ⟹ XP_006228413

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,226 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,075 - 76,872,691 (+)	NCBI
Rnor_6.0	1	78,069,066 - 78,079,698 (+)	NCBI
Rnor_5.0	1	79,335,318 - 79,346,214 (+)	NCBI

Sequence:

show sequence

TCAGAGGAGAGGGGAGGGACAAGACAGGAGAGGGGACGCTCGGGAGGAGGCCCCGCTCCGGCAG
ACAGCGGGTTAAGCGTCTCCGCGTGAACTTCCGGATGTGACACAGGCCGGGCCCGTGTGAGCCC
AGGAGCCGCCGCCACCCTCGGCCGCGATCCGCGGGTCTTGGCCACTCGGAGACCCCGGCACCCG
GCGGGGACCTCGGGGACCTCCGGCCGCGATGAGCCCCAGGCCGTGACCTCCCGAGCCCAGGACG
CGCGGCGCCGGCTCATGGCCCGGAGGTATGAGGAGCCGCGCCACTACCCCGGCATTACCGAGCA
CACGGCAGCCCTGGCCAGTTTTCCAGAGGCAGCACCTTCAGTACCTCGAGCTCCTGGGCCCTAT
GGCCCACACCGGCCGCCCCAACCCCAAGGTCCAGGCTTGGACAGCGATAGCTTGAAGAGAGAGA
AGGATGACATCTATGGACACCCCCTCTTCCCACTCTTGGCCCTGGTCTTTGAGAAGTGTGAGCT
GGCTACATGCTCGCCCCGTGATGGGGCCTCGGCTGGGCTGGGTTCACCCCCAGGTGGTGACGTC
TGCTCCTCTGACTCCTTCAATGAGGATATTGCTGCCTTTGCTAAGCAGATCCGCTCCGAGAGGC
CGCTGTTCTCTTCCAACCCGGAGCTGGACAACCTGATGGTCCAGGCCATCCAGGTACTCCGGTT
CCACCTGCTGGAGCTGGAGAAGGGGAAGATGCCCATAGACCTGGTGATCGAGGATCGGGATGGT
GGTTGCAGGGAGGACCTTGAGGACTACGCAGCCTCCTGCCCCAGCCTCCCAGACCAGAATACTA
CATGGATCAGAGACCATGAGGACAGTGGGTCTGTACATTTGGGGACCCCAGGTCCATCCAGCGG
AGGCCTGGCCTCCCAGAGCGGGGACAACTCAAGTGACCAAGGAGATGGGCTGGACACCAGCGTG
GCCTCTCCCAGCTCCGCAGGAGAGGATGAGGACCTGGACCTGGAGCGCAGACGGAACAAGAAGA
GGGGGATCTTCCCCAAAGTGGCCACCAACATCATGAGGGCCTGGTTGTTCCAGCATCTCTCGCA
CCCGTACCCCTCAGAAGAGCAAAAGAAACAGCTGGCCCAGGACACCGGGCTCACCATTCTGCAG
GTGAACAACTGGTTTATTAATGCCCGGAGACGGATAGTGCAGCCCATGATTGACCAGTCTAATC
GTACAGGGCAGGGTGCATCTTTCAACCCTGAGGGCCAGTCCATGGCAGGCTACACAGAGACTCA
ACCACATGTGACAGTCAGGACGCCAGGATCAATGGGGATGAATCTGAACTTAGAAGGAGAATGG
CATTACCTATAGAGGTTGGGGTCAAAAGGAGGGCCCCAGCCTCTGACTATGACCACCAGCCTTG
CACCTAATTGGTCCCTGCTGGTCCCTGGGCTTCAGGACTTCACCTCCAAAGCTCCCACCCCATT
CAACGCCTACCTCCCTGGGGCCCCCAGAGGCTTGAGGACCCAGAGCCCACTTGAGGGTTTCTCA
AGGGCAAAGACAAAGCCTCAAGGTCCTGCACCCTTCTTCTGCCCTCCCCTTTGCCCAGGACCTG
AGCTGAGAACTGGGCCAAGGTCTGAAGAAGATGGTGGCTGGGGCCCCAATCCAGGACAGAGAAG
AGACTGGGGTTGGGCAAGGATGGGCAAGGAAGGAGGGTCAGCTGGATCCAATGTTTGGGAGAAT
CCTTCATCTTCCTGCTCTCTGCCTCTCTCACCTCCCTTCTCTGACATTCTTCTACCTTTCCTTT
TTTTAATGATAAAGTCTTAAAAGTGCAAATCAAAA

hide sequence

RefSeq Acc Id:

XM_039081649 ⟹ XP_038937577

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,989,965 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,861,267 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081657 ⟹ XP_038937585

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,222 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,075 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081664 ⟹ XP_038937592

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,350 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,075 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081673 ⟹ XP_038937601

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,350 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,862,075 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081690 ⟹ XP_038937618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,992,348 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,864,170 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081693 ⟹ XP_038937621

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,992,348 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,864,170 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_039081694 ⟹ XP_038937622

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,992,348 - 86,000,873 (+)	NCBI
mRatBN7.2	1	76,864,170 - 76,872,691 (+)	NCBI

RefSeq Acc Id:

XM_063266345 ⟹ XP_063122415

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,219 - 86,000,873 (+)	NCBI

RefSeq Acc Id:

XM_063266346 ⟹ XP_063122416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,986,835 - 86,000,873 (+)	NCBI

RefSeq Acc Id:

XM_063266348 ⟹ XP_063122418

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,990,226 - 86,000,873 (+)	NCBI

RefSeq Acc Id:

XM_063266349 ⟹ XP_063122419

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,989,998 - 86,000,873 (+)	NCBI

RefSeq Acc Id:

XM_063266350 ⟹ XP_063122420

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	85,986,602 - 85,998,414 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101942	(Get FASTA)	NCBI Sequence Viewer
	NP_001386530	(Get FASTA)	NCBI Sequence Viewer
	NP_001386531	(Get FASTA)	NCBI Sequence Viewer
	XP_006228413	(Get FASTA)	NCBI Sequence Viewer
	XP_038937577	(Get FASTA)	NCBI Sequence Viewer
	XP_038937585	(Get FASTA)	NCBI Sequence Viewer
	XP_038937592	(Get FASTA)	NCBI Sequence Viewer
	XP_038937601	(Get FASTA)	NCBI Sequence Viewer
	XP_038937618	(Get FASTA)	NCBI Sequence Viewer
	XP_038937621	(Get FASTA)	NCBI Sequence Viewer
	XP_038937622	(Get FASTA)	NCBI Sequence Viewer
	XP_063122415	(Get FASTA)	NCBI Sequence Viewer
	XP_063122416	(Get FASTA)	NCBI Sequence Viewer
	XP_063122418	(Get FASTA)	NCBI Sequence Viewer
	XP_063122419	(Get FASTA)	NCBI Sequence Viewer
	XP_063122420	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI60854	(Get FASTA)	NCBI Sequence Viewer
	EDM08335	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000033135.5
	ENSRNOP00000063858
	ENSRNOP00000063858.3
	ENSRNOP00000096875.2

RefSeq Acc Id:	NP_001101942 ⟸ NM_001108472
- Peptide Label:	isoform 2
- UniProtKB:	D4A9U2 (UniProtKB/TrEMBL), A6J899 (UniProtKB/TrEMBL), A0A8I6AQ93 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARRYEEPRHYPGITEHTAALASFPEAAPSVPRAPGPYGPHRPPQPQGPGLDSDSLKREKDDIY GHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAKQIRSERPLFSS NPELDNLMVQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDGGCREDLEDY AASCPSLPDQNTTWIRDHEDSGSVHLGTPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSAGED EDLDLERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINAR RRIVQPMIDQSNRTGQGASFNPEGQSMAGYTETQPHVTVRTPGSMGMNLNLEGEWHYL hide sequence

RefSeq Acc Id:	XP_006228413 ⟸ XM_006228351
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARRYEEPRHYPGITEHTAALASFPEAAPSVPRAPGPYGPHRPPQPQGPGLDSDSLKREKDDIY GHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAKQIRSERPLFSS NPELDNLMVQAIQVLRFHLLELEKGKMPIDLVIEDRDGGCREDLEDYAASCPSLPDQNTTWIRD HEDSGSVHLGTPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRGIFP KVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQG ASFNPEGQSMAGYTETQPHVTVRTPGSMGMNLNLEGEWHYL hide sequence

Ensembl Acc Id:

ENSRNOP00000063858 ⟸ ENSRNOT00000068406

Ensembl Acc Id:

ENSRNOP00000033135 ⟸ ENSRNOT00000039538

RefSeq Acc Id:	XP_038937577 ⟸ XM_039081649
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937585 ⟸ XM_039081657
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937592 ⟸ XM_039081664
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937601 ⟸ XM_039081673
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937618 ⟸ XM_039081690
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_038937621 ⟸ XM_039081693
- Peptide Label:	isoform X10

RefSeq Acc Id:	XP_038937622 ⟸ XM_039081694
- Peptide Label:	isoform X11

Ensembl Acc Id:

ENSRNOP00000096875 ⟸ ENSRNOT00000118727

RefSeq Acc Id:	NP_001386530 ⟸ NM_001399601
- Peptide Label:	isoform 1
- UniProtKB:	B1H242 (UniProtKB/TrEMBL), A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386531 ⟸ NM_001399602
- Peptide Label:	isoform 3
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122420 ⟸ XM_063266350
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063122416 ⟸ XM_063266346
- Peptide Label:	isoform X3
- UniProtKB:	B1H242 (UniProtKB/TrEMBL), A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122419 ⟸ XM_063266349
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122415 ⟸ XM_063266345
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122418 ⟸ XM_063266348
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AQ93 (UniProtKB/TrEMBL)

Protein Domains

Homeobox

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A9U2-F1-model_v2	AlphaFold	D4A9U2	1-378	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689732

Promoter ID:

EPDNEW_R251

Type:

initiation region

Name:

Meis3_1

Description:

Meis homeobox 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	78,069,186 - 78,069,246	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308532	AgrOrtholog
BioCyc Gene	G2FUF-60621	BioCyc
Ensembl Genes	ENSRNOG00000021390	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000039538.8	UniProtKB/TrEMBL
	ENSRNOT00000068406	ENTREZGENE
	ENSRNOT00000068406.5	UniProtKB/TrEMBL
	ENSRNOT00000118727.2	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8364874	IMAGE-MGC_LOAD
InterPro	Homeobox_KN_domain	UniProtKB/TrEMBL
	Homeodomain	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	PKNOX/Meis_N	UniProtKB/TrEMBL
	TALE_homeobox	UniProtKB/TrEMBL
KEGG Report	rno:361514	UniProtKB/TrEMBL
MGC_CLONE	MGC:187606	IMAGE-MGC_LOAD
NCBI Gene	361514	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN TRANSCRIPTION FACTORS	UniProtKB/TrEMBL
Pfam	Homeobox_KN	UniProtKB/TrEMBL
	Meis_PKNOX_N	UniProtKB/TrEMBL
PhenoGen	Meis3	PhenoGen
PROSITE	HOMEOBOX_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000021390	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A0A8I6AQ93	ENTREZGENE, UniProtKB/TrEMBL
	A6J899	ENTREZGENE, UniProtKB/TrEMBL
	B1H242	ENTREZGENE, UniProtKB/TrEMBL
	D4A9U2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Meis3	Meis homeobox 3	Meis3_predicted	Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Meis3_predicted	Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse) (predicted)	Mrg2_predicted	myeloid ecotropic viral integration site-related gene 2 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-12	Mrg2_predicted	myeloid ecotropic viral integration site-related gene 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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