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Gene: Rbm38 (RNA binding motif protein 38) Rattus norvegicus

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Symbol:

Rbm38

Name:

RNA binding motif protein 38

RGD ID:

1308503

Description:

Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; regulation of gene expression; and regulation of myotube differentiation. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human RBM38 (RNA binding motif protein 38); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC366262; RNA-binding protein 38; RNA-binding region (RNP1, RRM) containing 1; Rnpc1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RBM38 (RNA binding motif protein 38)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Rbm38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rbm38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RBM38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RBM38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rbm38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RBM38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RBM38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rbm38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rbm38 (RNA binding motif protein 38)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DIAPH1 (diaphanous related formin 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RBM38 (RNA binding motif protein 38)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rbm38 (RNA binding motif protein 38)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rbm38 (RNA binding motif protein 38)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	rbm38 (RNA binding motif protein 38)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	sup-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	sup-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rbm38	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rbm38	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,219,898 - 182,232,723 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,219,899 - 182,232,714 (+)	Ensembl				GRCr8
mRatBN7.2	3	161,801,577 - 161,814,381 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,801,577 - 161,814,381 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	165,613,416 - 165,625,997 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,112,358 - 174,124,939 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,854,175 - 171,866,756 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,037,891 - 171,050,500 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,037,957 - 171,050,475 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,104,361 - 177,116,965 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	163,885,488 - 163,898,314 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	160,995,091 - 161,007,892 (+)	NCBI		Celera
RGSC_v3.1	3	163,785,484 - 163,804,355 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colorectal Neoplasms (ISO)

Neoplasm Invasiveness (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

cisplatin (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

endosulfan (EXP)

ethyl methanesulfonate (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

glycidol (EXP)

GSK-J4 (ISO)

ivermectin (ISO)

kojic acid (ISO)

Licochalcone B (ISO)

methapyrilene (EXP)

methoxyacetic acid (EXP)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Monobutylphthalate (EXP)

Nutlin-3 (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

quercetin (ISO)

quercitrin (ISO)

rotenone (EXP)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-UTR-mediated mRNA stabilization (ISO)

cell differentiation (IEA)

DNA damage response, signal transduction by p53 class mediator (ISO)

mRNA processing (IEA)

negative regulation of cell population proliferation (ISO)

regulation of cell cycle (ISO)

regulation of myotube differentiation (IEA,ISO)

regulation of RNA splicing (IBA,IEA,ISO)

RNA splicing (IEA)

Cellular Component

cytosol (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

mRNA 3'-UTR binding (IBA,ISO)

mRNA binding (IEA,ISO)

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:17050675	PMID:19285943	PMID:19817877	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Rbm38
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,219,898 - 182,232,723 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,219,899 - 182,232,714 (+)	Ensembl				GRCr8
mRatBN7.2	3	161,801,577 - 161,814,381 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,801,577 - 161,814,381 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	165,613,416 - 165,625,997 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,112,358 - 174,124,939 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,854,175 - 171,866,756 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,037,891 - 171,050,500 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,037,957 - 171,050,475 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,104,361 - 177,116,965 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	163,885,488 - 163,898,314 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	160,995,091 - 161,007,892 (+)	NCBI		Celera
RGSC_v3.1	3	163,785,484 - 163,804,355 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

RBM38
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	57,391,396 - 57,409,333 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	57,391,396 - 57,409,333 (+)	Ensembl			hg38	GRCh38
GRCh37	20	55,966,452 - 55,984,389 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	55,399,870 - 55,417,795 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	55,399,869 - 55,417,790	NCBI
Celera	20	52,706,709 - 52,724,603 (+)	NCBI		Celera
Cytogenetic Map	20	q13.31	NCBI
HuRef	20	52,749,536 - 52,765,964 (+)	NCBI		HuRef
CHM1_1	20	55,867,425 - 55,885,455 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	59,169,162 - 59,187,091 (+)	NCBI		T2T-CHM13v2.0

Rbm38
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	172,863,722 - 172,876,527 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	172,862,291 - 172,876,527 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	173,021,891 - 173,034,734 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	173,020,498 - 173,034,734 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	172,847,403 - 172,860,235 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	172,664,872 - 172,677,673 (+)	NCBI		MGSCv36	mm8
Celera	2	178,987,275 - 179,000,104 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	95.67	NCBI

Rbm38
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	2,036,124 - 2,052,139 (-)	Ensembl
ChiLan1.0	NW_004955445	2,036,314 - 2,050,882 (-)	NCBI	ChiLan1.0	ChiLan1.0

RBM38
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	63,142,478 - 63,160,533 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	63,135,598 - 63,153,644 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	53,731,641 - 53,749,688 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	55,010,623 - 55,027,746 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

RBM38
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	42,396,356 - 42,410,543 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	42,396,352 - 42,409,240 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	41,643,647 - 41,658,028 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	43,261,581 - 43,275,949 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	43,261,408 - 43,275,957 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	42,346,444 - 42,360,811 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	42,486,219 - 42,500,591 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	43,144,439 - 43,158,828 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rbm38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	183,056,936 - 183,072,570 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936530	227,266 - 249,285 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RBM38
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	57,783,154 - 57,797,990 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	57,783,156 - 57,802,495 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	64,947,372 - 64,962,216 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RBM38
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	6,709,975 - 6,727,534 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	6,711,458 - 6,727,353 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	54,772,349 - 54,789,867 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rbm38
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	23,854,023 - 23,868,345 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	23,854,069 - 23,868,016 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rbm38
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	144,951,251 - 144,964,008 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	161
Count of miRNA genes:	104
Interacting mature miRNAs:	132
Transcripts:	ENSRNOT00000008764
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	181611379	189428310	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat

Markers in Region

RH127569

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	161,814,098 - 161,814,301 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	171,050,218 - 171,050,420	NCBI	Rnor6.0
Rnor_5.0	3	177,116,683 - 177,116,885	UniSTS	Rnor5.0
RGSC_v3.4	3	163,898,037 - 163,898,239	UniSTS	RGSC3.4
Celera	3	161,007,615 - 161,007,817	UniSTS
RH 3.4 Map	3	1497.8	UniSTS
Cytogenetic Map	3	q42	UniSTS

RH134095

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	161,814,098 - 161,814,285 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	171,050,218 - 171,050,404	NCBI	Rnor6.0
Rnor_5.0	3	177,116,683 - 177,116,869	UniSTS	Rnor5.0
RGSC_v3.4	3	163,898,037 - 163,898,223	UniSTS	RGSC3.4
Celera	3	161,007,615 - 161,007,801	UniSTS
RH 3.4 Map	3	1496.8	UniSTS
Cytogenetic Map	3	q42	UniSTS

X75316

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	182,232,481 - 182,232,641 (+)	Marker Load Pipeline
mRatBN7.2	3	161,814,138 - 161,814,299 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	171,050,258 - 171,050,418	NCBI	Rnor6.0
Rnor_5.0	3	177,116,723 - 177,116,883	UniSTS	Rnor5.0
RGSC_v3.4	3	163,898,077 - 163,898,237	UniSTS	RGSC3.4
Celera	3	161,007,655 - 161,007,815	UniSTS
Cytogenetic Map	3	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001398951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001398952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000008764 ⟹ ENSRNOP00000008764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	182,219,899 - 182,232,714 (+)	Ensembl
mRatBN7.2 Ensembl	3	161,801,577 - 161,814,381 (+)	Ensembl
Rnor_6.0 Ensembl	3	171,037,957 - 171,050,475 (+)	Ensembl

RefSeq Acc Id:

NM_001108965 ⟹ NP_001102435

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,220,363 - 182,232,723 (+)	NCBI
mRatBN7.2	3	161,802,021 - 161,814,381 (+)	NCBI
Rnor_6.0	3	171,037,896 - 171,050,495 (+)	NCBI
Rnor_5.0	3	177,104,361 - 177,116,965 (+)	NCBI
RGSC_v3.4	3	163,885,488 - 163,898,314 (+)	RGD
Celera	3	160,995,091 - 161,007,892 (+)	RGD

Sequence:

show sequence

AAAGGCGGCCAGCGGCTCGCAGGGCGCGGAGTAGACGCTTCGCCGCGGACCGAGGAGCGGCGCG
GAACGGCGTGGGGAACTCGGATTCGGCCTGCGACACCCCCGCATGCGCCGGCCGGCCCGGTAGC
GGCGGCCCCAATGCTGCTGCAGCCCGCGTGCGCCCCGAGTGTGTTTCCGCGGCCGTCCGCCGCC
CCCAGCGCCATGCACGGCTCACAGAAGGACACCACGTTCACCAAGATCTTCGTGGGCGGCCTGC
CCTACCACACCACCGACGCATCGCTCAGAAAGTACTTCGAGGGCTTTGGAGACATCGAGGAGGC
CGTGGTCATCACCGACCGCCAGACCGGCAAGTCCCGCGGCTACGGCTTCGTGAGTGCCCGCGGC
GCGCGCACCTGCCGCCGCCCCTCCCCCACCGCCTCCCAGACCCGCCGCGCGCAGCCGGGACTCC
GGGGCTTCCCGGGGCCGTCGGCCCTTCCCCCACACTTTCCAGCCGCCCCAACTAAGCGTAAGCT
TTAGCGCCAGCGACTTGAAGACGGTTTCCCACTTCCTTCCACTCTAGTGTCCCCAAACTAATTC
TCTGAGAAAGTTAACGGTACTTACTGATGGCCAGAGCAACCGGGGTTGGGGGGGGGGGGACGAC
TCCTCTTGGGGTTCACTTAACTCCACCTCCCAGGGGATTGTCGCTGCCCTTGAAGGCACTCAGA
ACTTGAACTCGGGAAGGAGCTGCAGTCCTGGAGGCAGAGAAGACAGTGCCCCAAGGGTCCTAAA
TACCAGATACTCTCCTGGGAGGAGAAAGACCCAGAGGGCCCGATGCCCGGGCAAAACCCTCTTT
CCTTCTGTGCCCTGTTTCCCTCAGCCAGCCACCGAAGCCCCTGACCCTCTGTTTTCCTACAGGT
GACCATGGCAGATCGGGCAGCAGCTGATAGGGCTTGCAAAGACCCTAACCCTATCATCGATGGC
CGCAAGGCCAACGTGAACCTGGCCTACCTGGGTGCCAAGCCTAGGAGCCTGCAGACGGGCTTTG
CCGTTGGTGTGCAGCAACTACACCCCACCTTGATCCAGCGCACCTACGGGCTGACTCCCCACTA
CATCTACCCACCAGCCATTGTACAGCCCAGCGTGGTGATCCCTGCCACCCCTGTCCCGTCACTG
TCCTCGCCCTACCTTGAGTATACACCAGCCAGCCCAGCCTACGCTCAGTACCCTCCAGCCACTT
ACGACCAGTACCCATACGCCGCCTCGCCTGCCACGGCCACCAGCTTCGTGGGCTATGGCTACCC
TGCCGCCATTCCCCCAGCCTTGTCTGCCACGGCACCTGCAGGCACCACCTTCGTGCAGTACCAG
GCACCTCAGCTACAGCCTGACAGGATGCAGTGAGGCGCGTCCTGCACAGGGCCACAGCCACCAC
CTGCCAGCCTTGGGAGCCACCACCACATGGGTCTCCTCAGGCCCCGGGGCCCACCTGCCCTGAA
GGCACCAGCAAGCTTCTTCTGCAGCCCTGCCGTGCTTGAGGAAGGGCCTGAGAAGGAAGGTACA
CTCTGGGAGTTCTGCAGCCACTCTGTGCTAGGTGCCTTACTCTGGGACGCATAAGACGTCCTCC
CTCCTCTTTGGGAACTGTCCTCTTGGTGGATCCGGGTTCCCGAAACCCCGCCCAGGTGCCCTCA
GCCGAAGCACTGTGCCATGTCCTGCTGGGAATTTTCTGTGGTGCAGGCAAGACCATCAGCACCG
AGAGCCCCAAACCTATTTTTACTTAGAGACTGGCTTTGGTCAGTAGCTCCCTGTGGAGACAGTT
GACAGTATTTCTCTGTGCCGGTGTCACTGATGGAGCTGCCCCTCCCCCGCAGGGTTGCCCTCAC
AAACTGCAGCCCTGCAGGGGGCTGGGCTCCTGTCTGCTGATGCTGCCCACCTCACCTGCAGAGG
TGCCTGCCAGGGCGAGTTCTCAGGTGTCTGTTGCTGTGCCATGGGGGCCTTCTTCTGGCCCTGT
GCCCCTCAGGCAGGCTCTGTGCCCACCCAGCCCCCCATTGTCACCTGTACCAGTCTGGAGCATG
ACCTAGCTGCACAGGGAGAAGGTCCAGCCCACACACGTCTGGGAGGGGAGGAGTGGGCATCTCT
GGCAGCATGGGCTGCCCACAGGCTGGGCAGTGGGTCCCTCCACACCTACCTCAGGGAGCCAGTG
TGTAGGCACTCCACAGCATGCCTGTTAGTCAAGGCCTGGAGGACAGAGGGAGTAATGTTATAAT
AATATTTTTATTAGAATGTTCTGATTATAAAAAATAAAACTTGTTTTCTTTAAAG

hide sequence

RefSeq Acc Id:

NM_001398951 ⟹ NP_001385880

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,219,919 - 182,232,723 (+)	NCBI
mRatBN7.2	3	161,801,577 - 161,814,381 (+)	NCBI

RefSeq Acc Id:

NM_001398952 ⟹ NP_001385881

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,219,919 - 182,232,723 (+)	NCBI
mRatBN7.2	3	161,801,577 - 161,814,381 (+)	NCBI

RefSeq Acc Id:

XM_063284292 ⟹ XP_063140362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,219,898 - 182,232,723 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102435	(Get FASTA)	NCBI Sequence Viewer
	NP_001385880	(Get FASTA)	NCBI Sequence Viewer
	NP_001385881	(Get FASTA)	NCBI Sequence Viewer
	XP_063140362	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85126	(Get FASTA)	NCBI Sequence Viewer
	EDL85127	(Get FASTA)	NCBI Sequence Viewer
	EDL85128	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000008764
	ENSRNOP00000008764.5

RefSeq Acc Id:	NP_001102435 ⟸ NM_001108965
- Peptide Label:	isoform 2
- UniProtKB:	A6KKY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYI YPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPATATSFVGYGYPA AIPPALSATAPAGTTFVQYQAPQLQPDRMQ hide sequence

Ensembl Acc Id:

ENSRNOP00000008764 ⟸ ENSRNOT00000008764

RefSeq Acc Id:	NP_001385880 ⟸ NM_001398951
- Peptide Label:	isoform 1
- UniProtKB:	D3ZGE9 (UniProtKB/TrEMBL), A6KKY8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385881 ⟸ NM_001398952
- Peptide Label:	isoform 2
- UniProtKB:	A6KKY9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140362 ⟸ XM_063284292
- Peptide Label:	isoform X1

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZGE9-F1-model_v2	AlphaFold	D3ZGE9	1-237	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692710

Promoter ID:

EPDNEW_R3235

Type:

multiple initiation site

Name:

Rbm38_1

Description:

RNA binding motif protein 38

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	171,037,923 - 171,037,983	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308503	AgrOrtholog
BioCyc Gene	G2FUF-46522	BioCyc
Ensembl Genes	ENSRNOG00000006420	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008764	ENTREZGENE
	ENSRNOT00000008764.8	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RNA-binding_reg	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
KEGG Report	rno:366262	UniProtKB/TrEMBL
NCBI Gene	366262	ENTREZGENE
PANTHER	GEO13361P1-RELATED	UniProtKB/TrEMBL
	RNA-BINDING PROTEIN 38	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
PhenoGen	Rbm38	PhenoGen
PROSITE	RRM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000006420	RatGTEx
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A6KKY8	ENTREZGENE, UniProtKB/TrEMBL
	A6KKY9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZGE9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Rbm38	RNA binding motif protein 38	Rnpc1_predicted	RNA-binding region (RNP1, RRM) containing 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Rnpc1_predicted	RNA-binding region (RNP1, RRM) containing 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD