Nkd1 (NKD inhibitor of WNT signaling pathway 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nkd1 (NKD inhibitor of WNT signaling pathway 1) Rattus norvegicus
Analyze
Symbol: Nkd1
Name: NKD inhibitor of WNT signaling pathway 1
RGD ID: 1308491
Description: Predicted to enable PDZ domain binding activity. Predicted to be involved in several processes, including convergent extension; positive regulation of protein catabolic process; and regulation of signal transduction. Predicted to be located in plasma membrane. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytoplasm. Orthologous to human NKD1 (NKD inhibitor of WNT signaling pathway 1); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC364952; naked cuticle 1 homolog; naked cuticle 1 homolog (Drosophila); naked cuticle homolog 1; naked cuticle homolog 1 (Drosophila); NKD1, WNT signaling pathway inhibitor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81934,649,803 - 34,722,846 (-)NCBIGRCr8
mRatBN7.21918,476,344 - 18,549,380 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1918,476,344 - 18,549,380 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1920,155,899 - 20,228,953 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01925,350,523 - 25,423,571 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01928,308,236 - 28,381,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01919,434,720 - 19,509,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1919,436,333 - 19,509,087 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01930,468,091 - 30,539,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41919,759,537 - 19,832,877 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11919,764,085 - 19,876,798 (-)NCBI
Celera1918,362,013 - 18,434,956 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-tert-butylhydroquinone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
celastrol  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
leflunomide  (ISO)
lithium chloride  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
naphthalene  (ISO)
niclosamide  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
XAV939  (ISO)
xylitol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11274398   PMID:11356022   PMID:12477932   PMID:15687260  


Genomics

Comparative Map Data
Nkd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81934,649,803 - 34,722,846 (-)NCBIGRCr8
mRatBN7.21918,476,344 - 18,549,380 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1918,476,344 - 18,549,380 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1920,155,899 - 20,228,953 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01925,350,523 - 25,423,571 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01928,308,236 - 28,381,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01919,434,720 - 19,509,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1919,436,333 - 19,509,087 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01930,468,091 - 30,539,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41919,759,537 - 19,832,877 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11919,764,085 - 19,876,798 (-)NCBI
Celera1918,362,013 - 18,434,956 (-)NCBICelera
Cytogenetic Map19p11NCBI
NKD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381650,548,396 - 50,649,249 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1650,548,396 - 50,649,249 (+)EnsemblGRCh38hg38GRCh38
GRCh371650,582,307 - 50,683,160 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361649,139,742 - 49,226,142 (+)NCBINCBI36Build 36hg18NCBI36
Build 341649,139,741 - 49,226,142NCBI
Celera1635,097,548 - 35,183,963 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1636,470,058 - 36,562,565 (+)NCBIHuRef
CHM1_11651,989,797 - 52,082,309 (+)NCBICHM1_1
T2T-CHM13v2.01656,346,149 - 56,446,862 (+)NCBIT2T-CHM13v2.0
Nkd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39889,247,961 - 89,321,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl889,247,982 - 89,321,512 (+)EnsemblGRCm39 Ensembl
GRCm38888,521,342 - 88,594,887 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl888,521,354 - 88,594,884 (+)EnsemblGRCm38mm10GRCm38
MGSCv37891,045,243 - 91,118,786 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36891,411,475 - 91,482,431 (+)NCBIMGSCv36mm8
Celera892,795,568 - 92,872,396 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map843.36NCBI
Nkd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554338,622,568 - 8,699,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554338,622,568 - 8,705,356 (+)NCBIChiLan1.0ChiLan1.0
NKD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21860,005,469 - 60,093,914 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11665,911,106 - 65,999,652 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01630,811,342 - 30,912,346 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11649,691,011 - 49,778,732 (+)NCBIpanpan1.1PanPan1.1panPan2
NKD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1264,720,059 - 64,806,868 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl264,722,243 - 64,807,875 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,294,557 - 61,379,444 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0265,267,153 - 65,351,863 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl265,267,238 - 65,352,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1262,090,536 - 62,175,430 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0263,110,509 - 63,195,070 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0263,998,132 - 64,083,111 (-)NCBIUU_Cfam_GSD_1.0
Nkd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934955,931,133 - 56,009,736 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364753,579,501 - 3,655,205 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364753,559,754 - 3,655,216 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NKD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl634,223,884 - 34,319,528 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1634,223,888 - 34,319,584 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NKD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1536,350,071 - 36,433,936 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl536,407,285 - 36,432,995 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604740,068,322 - 40,152,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nkd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247576,046,361 - 6,134,470 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247576,035,356 - 6,134,477 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nkd1
306 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:288
Count of miRNA genes:187
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000019301
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat

Markers in Region
D19Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21918,547,986 - 18,548,140 (+)MAPPERmRatBN7.2
Rnor_6.01919,506,894 - 19,507,047NCBIRnor6.0
Rnor_5.01930,537,945 - 30,538,098UniSTSRnor5.0
RGSC_v3.41919,831,724 - 19,831,877UniSTSRGSC3.4
Celera1918,433,563 - 18,433,716UniSTS
Cytogenetic Map19p11UniSTS
RH128487  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21918,474,768 - 18,474,981 (+)MAPPERmRatBN7.2
Rnor_6.01919,434,758 - 19,434,970NCBIRnor6.0
Rnor_5.01930,466,516 - 30,466,728UniSTSRnor5.0
RGSC_v3.41919,757,091 - 19,757,303UniSTSRGSC3.4
Celera1918,360,438 - 18,360,650UniSTS
Cytogenetic Map19p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 6 18 4 6 4 67 22 33 11
Low 1 36 39 37 13 37 7 7 7 13 8 7
Below cutoff 1 1 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019301   ⟹   ENSRNOP00000019301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1918,476,344 - 18,549,380 (-)Ensembl
Rnor_6.0 Ensembl1919,436,333 - 19,509,087 (-)Ensembl
RefSeq Acc Id: NM_001271381   ⟹   NP_001258310
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81934,649,803 - 34,722,846 (-)NCBI
mRatBN7.21918,476,344 - 18,549,380 (-)NCBI
Rnor_6.01919,436,333 - 19,509,087 (-)NCBI
Rnor_5.01930,468,091 - 30,539,237 (-)NCBI
Celera1918,362,013 - 18,434,956 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258310 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL87527 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019301
  ENSRNOP00000019301.7
Reference Protein Sequences
RefSeq Acc Id: NP_001258310   ⟸   NM_001271381
- UniProtKB: D4AAV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019301   ⟸   ENSRNOT00000019301
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAV5-F1-model_v2 AlphaFold D4AAV5 1-471 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700976
Promoter ID:EPDNEW_R11500
Type:single initiation site
Name:Nkd1_1
Description:naked cuticle homolog 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01919,509,141 - 19,509,201EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308491 AgrOrtholog
BioCyc Gene G2FUF-6278 BioCyc
Ensembl Genes ENSRNOG00000014293 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019301 ENTREZGENE
  ENSRNOT00000019301.8 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  Nkd-like UniProtKB/TrEMBL
KEGG Report rno:364952 UniProtKB/TrEMBL
NCBI Gene 364952 ENTREZGENE
PANTHER PROTEIN NAKED CUTICLE HOMOLOG 1 UniProtKB/TrEMBL
  PTHR22611 UniProtKB/TrEMBL
PhenoGen Nkd1 PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014293 RatGTEx
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt D4AAV5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-04 Nkd1  NKD inhibitor of WNT signaling pathway 1  Nkd1  NKD1, WNT signaling pathway inhibitor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-12-04 Nkd1  NKD1, WNT signaling pathway inhibitor  Nkd1  naked cuticle homolog 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-14 Nkd1  naked cuticle homolog 1  Nkd1  naked cuticle homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-20 Nkd1  naked cuticle homolog 1 (Drosophila)  Nkd1  naked cuticle 1 homolog (Drosophila)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Nkd1  naked cuticle 1 homolog (Drosophila)   Nkd1_predicted  naked cuticle 1 homolog (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Nkd1_predicted  naked cuticle 1 homolog (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED