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Gene: Mybl2 (MYB proto-oncogene like 2) Rattus norvegicus

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Symbol:

Mybl2

Name:

MYB proto-oncogene like 2

RGD ID:

1308474

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of neuron apoptotic process. Predicted to be located in nucleoplasm. Predicted to be part of Myb complex. Predicted to be active in nucleus. Orthologous to human MYBL2 (MYB proto-oncogene like 2); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC296344; myb-related protein B; myeloblastosis oncogene-like 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYBL2 (MYB proto-oncogene like 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mybl2 (myeloblastosis oncogene-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mybl2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYBL2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYBL2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mybl2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYBL2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYBL2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mybl2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mybl2 (MYB proto-oncogene like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KDM3B (lysine demethylase 3B)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	MYBL2 (MYB proto-oncogene like 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mybl2 (myeloblastosis oncogene-like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mybl2b (v-myb avian myeloblastosis viral oncogene homolog-like 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	BAS1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Myb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Myb	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mybl2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mybl2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	172,124,765 - 172,153,221 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	172,116,550 - 172,153,221 (+)	Ensembl				GRCr8
mRatBN7.2	3	151,705,254 - 151,733,714 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	151,705,288 - 151,733,708 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	155,513,382 - 155,541,568 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	164,012,331 - 164,040,517 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	161,755,932 - 161,784,118 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	159,421,638 - 159,450,087 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	159,421,671 - 159,450,086 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	165,617,173 - 165,645,610 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	153,925,908 - 153,954,323 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	150,362,664 - 150,391,069 (+)	NCBI		Celera
RGSC_v3.1	3	153,831,924 - 153,858,958 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISS)

COVID-19 (ISO)

hepatocellular carcinoma (ISO)

myelodysplastic syndrome (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile (EXP,ISO)

1-naphthyl isothiocyanate (EXP)

14-Deoxy-11,12-didehydroandrographolide (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-palmitoylglycerol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4-hydroxynon-2-enal (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

antimycin A (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

calcitriol (ISO)

calyculin A (ISO)

carbon nanotube (ISO)

carmustine (EXP)

chlorpromazine (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

citalopram (EXP,ISO)

cobalt dichloride (EXP,ISO)

copper atom (EXP)

copper(0) (EXP)

coumarin (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

DDE (ISO)

dexamethasone (ISO)

diallyl trisulfide (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

diethyl maleate (EXP)

dioxygen (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

escitalopram (EXP,ISO)

exemestane (ISO)

fenvalerate (EXP)

fipronil (EXP)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

genistein (ISO)

gentamycin (EXP)

geraniol (ISO)

glucose (ISO)

glycidol (EXP)

Heliotrine (EXP)

hydralazine (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

L-ascorbic acid (ISO)

Lasiocarpine (EXP,ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

lucanthone (ISO)

methotrexate (EXP)

methylseleninic acid (ISO)

N-methyl-4-phenylpyridinium (ISO)

naphthalene (ISO)

nickel dichloride (EXP)

nicotine (ISO)

okadaic acid (ISO)

oxaliplatin (EXP,ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

PCB138 (ISO)

phenethyl isothiocyanate (ISO)

phenobarbital (ISO)

phytoestrogen (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

senecionine (EXP)

silicon dioxide (ISO)

sirolimus (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP,ISO)

sulforaphane (EXP)

sunitinib (ISO)

tamoxifen (ISO)

Tanshinone I (ISO)

testosterone (ISO)

thioacetamide (EXP)

tioguanine (EXP)

titanium dioxide (EXP)

topotecan (EXP)

Tributyltin oxide (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

Triptolide (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vorinostat (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

mitotic cell cycle (IBA)

mitotic spindle assembly (ISO)

positive regulation of neuron apoptotic process (IMP)

positive regulation of transcription by RNA polymerase II (IBA,ISO)

Cellular Component

Myb complex (ISO)

nucleoplasm (ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage.	Liu DX, etal., J Neurosci. 2004 Oct 6;24(40):8720-5.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10770937	PMID:11114719	PMID:16903783	PMID:17979185	PMID:18548008	PMID:19796622	PMID:20439489	PMID:21419759	PMID:31074036	PMID:31444477

Genomics

Comparative Map Data

Mybl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	172,124,765 - 172,153,221 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	172,116,550 - 172,153,221 (+)	Ensembl				GRCr8
mRatBN7.2	3	151,705,254 - 151,733,714 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	151,705,288 - 151,733,708 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	155,513,382 - 155,541,568 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	164,012,331 - 164,040,517 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	161,755,932 - 161,784,118 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	159,421,638 - 159,450,087 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	159,421,671 - 159,450,086 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	165,617,173 - 165,645,610 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	153,925,908 - 153,954,323 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	150,362,664 - 150,391,069 (+)	NCBI		Celera
RGSC_v3.1	3	153,831,924 - 153,858,958 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

MYBL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	43,667,114 - 43,716,482 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	43,667,019 - 43,716,495 (+)	Ensembl			hg38	GRCh38
GRCh37	20	42,295,754 - 42,345,122 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	41,729,123 - 41,778,536 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	41,729,122 - 41,778,536	NCBI
Celera	20	39,003,174 - 39,052,551 (+)	NCBI		Celera
Cytogenetic Map	20	q13.12	NCBI
HuRef	20	39,030,966 - 39,080,488 (+)	NCBI		HuRef
CHM1_1	20	42,199,374 - 42,248,808 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	45,400,313 - 45,449,683 (+)	NCBI		T2T-CHM13v2.0

Mybl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Build 34	6	46,205,870 - 46,222,237	NCBI
GRCm39	2	162,896,246 - 162,926,608 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	162,896,607 - 162,926,608 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	163,054,327 - 163,084,688 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	163,054,687 - 163,084,688 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	162,880,371 - 162,910,423 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	162,746,076 - 162,776,128 (+)	NCBI		MGSCv36	mm8
Celera	2	169,001,317 - 169,031,320 (+)	NCBI		Celera
Cytogenetic Map	2	H2	NCBI
cM Map	2	84.0	NCBI

Mybl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	13,496,919 - 13,530,689 (-)	Ensembl
ChiLan1.0	NW_004955445	13,496,919 - 13,530,689 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYBL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	49,407,322 - 49,455,166 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	49,400,422 - 49,448,267 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	40,005,482 - 40,053,324 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	41,099,325 - 41,146,822 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	41,099,368 - 41,146,423 (+)	Ensembl			panPan2	panpan1.1

MYBL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	31,339,570 - 31,382,626 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	31,343,997 - 31,382,624 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	30,983,123 - 31,025,849 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	32,046,538 - 32,089,827 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	32,051,535 - 32,089,825 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	31,310,869 - 31,353,896 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	31,422,213 - 31,465,277 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	31,963,002 - 32,006,311 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mybl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	180,352,693 - 180,387,306 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	2,918,951 - 2,953,467 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	2,918,924 - 2,953,467 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYBL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	46,256,257 - 46,287,927 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	46,256,245 - 46,287,929 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	51,696,566 - 51,726,944 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYBL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	20,097,179 - 20,148,998 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	20,097,108 - 20,148,926 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	68,828,866 - 68,880,606 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mybl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	10,630,158 - 10,664,982 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624790	10,629,771 - 10,665,187 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mybl2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	154,904,065 - 154,933,214 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	177
Count of miRNA genes:	122
Interacting mature miRNAs:	146
Transcripts:	ENSRNOT00000010343
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
1300113	Bp176	Blood pressure QTL 176	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	166376089	177728348	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161799493	176036425	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat

Markers in Region

BI292471

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	151,721,453 - 151,721,611 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	159,437,832 - 159,437,989	NCBI	Rnor6.0
Rnor_5.0	3	165,633,355 - 165,633,512	UniSTS	Rnor5.0
RGSC_v3.4	3	153,942,069 - 153,942,226	UniSTS	RGSC3.4
Celera	3	150,378,815 - 150,378,972	UniSTS
RH 3.4 Map	3	1387.4	UniSTS
Cytogenetic Map	3	q42	UniSTS

RH134987

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	151,733,381 - 151,733,564 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	159,449,760 - 159,449,942	NCBI	Rnor6.0
Rnor_5.0	3	165,645,283 - 165,645,465	UniSTS	Rnor5.0
RGSC_v3.4	3	153,953,997 - 153,954,179	UniSTS	RGSC3.4
Celera	3	150,390,743 - 150,390,925	UniSTS
RH 3.4 Map	3	1382.2	UniSTS
Cytogenetic Map	3	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	10	66	160	90	89	58	92	58	6	349	191	11	139	78	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001430185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010343 ⟹ ENSRNOP00000010343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	172,124,805 - 172,153,221 (+)	Ensembl
mRatBN7.2 Ensembl	3	151,705,288 - 151,733,708 (+)	Ensembl
Rnor_6.0 Ensembl	3	159,421,671 - 159,450,086 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000128666 ⟹ ENSRNOP00000106433

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	172,120,748 - 172,153,221 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149485 ⟹ ENSRNOP00000103500

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	172,116,550 - 172,153,221 (+)	Ensembl

RefSeq Acc Id:

NM_001106536 ⟹ NP_001100006

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	172,124,805 - 172,153,221 (+)	NCBI
mRatBN7.2	3	151,705,288 - 151,733,708 (+)	NCBI
Rnor_6.0	3	159,421,671 - 159,450,086 (+)	NCBI
Rnor_5.0	3	165,617,173 - 165,645,610 (+)	NCBI
RGSC_v3.4	3	153,925,908 - 153,954,323 (+)	RGD
Celera	3	150,362,664 - 150,391,069 (+)	RGD

Sequence:

show sequence

AAAGTGGTTCAGTGCGCTCCCTAGGCAGCTGCAGTTCCTGGGAACGTGCGACAAGACCTGCAGA
CACGCTGACGCCTCAGAGCACCGCCTGGGGCCCGGAGCGGCCGGTGCAGCCTGAGTCCTGACCC
CGGCCCGGCTCCCGCTCCGGGCTCGGCCGGCGGGCGTAAGGGCGCGGCGGGGTCCGGGCCGGGG
GGATGTCTCGGCGGACGCGCTGTGAGGAACTGGATGAGTTACGCTACCAGGACACGGACTCAGA
CCTCCTGGAGCAGAGAGACAACAAATGTAAGGTCAAATGGACCCACGAGGAGGATGAGCTACTG
AGGGCCCTGGTGAGGCAGTTTGGACAGCAAGACTGGAAGTTCCTGGCCAGTCACTTTCCTAACC
GCACAGACCAGCAATGCCAGTACCGGTGGCTGAGGGTTTTGAATCCAGACCTTGTTAAGGGACC
GTGGACCAAAGAGGAAGATCAGAAGGTCATTGAGCTGGTCAAGAAGTACGGCACAAAACAGTGG
ACGCTCATTGCCAAGCACCTGAAGGGCCGTCTTGGGAAGCAGTGTCGTGAGCGCTGGCACAACC
ATCTCAACCCTGAGGTGAAGAAGTCCTGCTGGACAGAGGAGGAAGATCGGATCATCTGTGAGGC
CCATAAAGTGCTGGGCAACCGCTGGGCTGAGATCGCCAAGATGCTGCCAGGGAGGACAGACAAT
GCTGTGAAGAATCACTGGAATTCCACCATCAAAAGGAAAGTCGACACGGGAGGGTTCCCAAACG
AGTCCAGAGACTGCAAGCCTGTCTACTTGCTCTTGGAGCTCGAGGACAAGGATTACCAACAGAA
TGTCCAGCCTGTGGAAGGCCCGGGAAGTCTTGTGAGCAGCTGGCCCCTGGCGCCCTCTACTGTG
AAGGAGGAGGAGAGCAGCGAGGAGGAGGCTGCCGTGGCTACTACTTCTAAGGAACACAAGCAGG
AGCCCGTCCCCACTGATCTGGGGGAAGTGCGCACCCCAGAGCCCCTGGAATTCCTCAAGCGTGA
ATACCAGGAGGAATCCTCCCCAGAAACAAGCCTGCCCTACAAGTGGGTGGTGGAGGCCGCGAAC
CTCCTCATCCCTGCTGTGGAGTCCAGCCTCTCCGAAGCTCTGGACTTGATCGAGTCGGACCCCG
ATGCTTGGTGTGACCTCAGTAAATTTGATCTTCCTGAAGAACCGTCTGCAGAGGGCAGTGTCAA
CAGTAGCCCAGTGCAACTCCAGACACCGCAGCAGCAGCAACAGCACCAGCAGGCACTGTCATTC
CACCAGGCTGCCACACCAGGGCCCAGTGTGACTGAGTATCGCCTTGATGGCCACACTATTTCAG
ACCTGAGCCGGAGCAGCCGGGGAGAGCTGATCCCCATTTCCCCAAGCACTGAGTTTGGGGGCTC
AGGCATTGGCACACCGCCCTCAGTGCTCAAGCGACAGAAGAAACGGCGCGTGGCCCTGTCGCCT
GTCACAGAGAACAGTGCCAGCTTGTCCTTCCTGGACTCCTGTAATAGCCTTACCCCGAAGAGCA
CACCTGTCAAAACCCTTCCCTTCTCTCCTTCCCAGTTTCTGAACTTCTGGAACAAACAGGATAC
CCTGGAGTTGGAGAGCCCCTCCCTGACGTCCACTCCGGTGTGCAGCCAAAAGGTGGTAGTCACC
ACACCCTTGCACAGGGATAAGACGCCCCTGCACCAGAAGTATCCATCGTTTGTAACCCCAGATC
AGAAGTATTCCATGGACAACACTCCCCACACACCAACCCCGTTCAAGAATGCTCTGGAGAAATA
TGGACCACTGAAACCCCTGCCCCAAACCCCACACCTGGAAGAGGACTTGAAGGAGGTGCTTCGT
TCCGAGGCTGGCATTGAGCTCATCATTGAGGATGACATGAGACCCGAGAAACAGAAGAGAAAGC
CTGGGCTCCGGCGAAGCCCTATCAAGAAGGTTCGGAAGTCTCTGGCTCTTGACATTGTGGATGA
GGATGGGAAGATGATGTCATCGACCTCGCCCAAGACTCTGTCCTTGCCAACCAGTGTCCCATCC
AGCTCCTCTGGCTTCATCTTGCCGGGTATCAAGGAGGATAACAGCCTGCTCAACCAGGGCTTCC
TACAGGCCAAACCCGAGAAGGTGGTGGCCACCCAGAAGCCCCGGAGCCACATTCCAGCCCCTGC
TCCTATGACCCGTGCCTGGAAGACGGTGGCCTGTGGGGGCACTAAAGACCAGCTCTTCATGCAA
GAGAAGGCCCGGCAGCTCCTGGGCCGTCTGAAGTCCAGCCACACATCTCGGACCCTCATTCTGT
CCTGAGGGGCTTGCAGGGAACAAGCCAGCTCTCATGTTTACAGGGGTAGGGTGTGGGGTAAGGT
GTGCGTTGAAGTCACATTAAATGACCAGCTTCAGGAAGTCTTCTGCCAGCCCCTCAGTCTGCTC
AGGTGGCAGAAGTCACATGGTACATCTCTTCCCCCGGTCTAGCCTTTGTGAAGTTCCTGGTGGT
GCTAATAGAACAAAGTCCCACTCCTGGGCCTGCCTGCCCTCCGCCCAGTGCCACAAGGAGCCCT
ATTAGGTTCTCCCAGGCTCTCATCCAGACTCCTGCTTAGGATGGGGGTGTGGCGAGGGGTGCTC
CTTCCCTCGTTTGTTGGTACACTGTCTCCACAATAAAATACCGTTCTCCCTATGCAGCCCCGAC
TCTGCCCTCTGAGTCTTGAAGTGCCTTGAAGGCCCTCTCCTGACACGTAGGCCTGTAGACCTCT
GTTCTTGGGTACAGCTTTACCCAGTGAGCATCTCTGCAAAGCTCCCAAGAGCTCTGAGTGGATG
AAGATGGGTTCTGAGAACCTGTTAGAACGGTGTATTCACCTTTGCCCTGATGCCTCAGGGCCAT
GGCTTGGGGCATGGGTGGTTCTTATGGCTTCCACGGAGCAGCTGCTGCCTTAAGCCGAGCCTGC
CATAGGTAAGACCATTAATATAGGTAGAGGGATGGATGGCAGGCCTTTCGACTCTGGCCAATGT
GTGGAAGGCTGCCCAGCTCCTGGATCTTTTATCCTGAATTGGTGGCAGCCATGGCCTGGGCTGT
CACCTCCCTTGGAGTCAGTGGGTAGAGCGTGGTCCATAGTTCAGTCAGTTAAGAGCTTGACTAG
GGAGATGCTGAGCCTAATGTCTACGTTAGGAAGTGTTGTTTTCTGTAGCCTGCCTGGGTGTCCC
TGGGTTGGGAGTTAGATGGACCTATGGGAGGTCTAGACTTAGTCCTGGTTAAAGGGAGACTTGA
GGCAAATGTTCTCCAACTGGGCAAGAGATAACGTCTGAAGAAGACTGCGCTAGCACACCGGAGT
CCAGGCGCTCTCCTGTAAAAGATACGGGAGCCGGGCTGTGCTCTCACACTGTGCCTACTGCAGC
CTCCTTGTCTGAGCCCCATGCTCAGTGAGCAGCACCTGCCTCACCCCTGGCTCTCTAGTTCTTT
TCTCAGAATGGCTAAGGCGACTAGCAGCCACGCGTGTGTGCGGTCTGTGCTTGAGAAGGCATGG
TGGAGGACAGGCTGTCAAGCAGAGGATAAAGGCTGCTGGTGCCTACCAGGCTCTCCTACAGTCG
GGGCTCTCTAAGGGGTGCCGCAGCCTGCATTTAGGGGGGCTCTTTTAACCCTGGAATTTCCTCA
TAGACACACGCAAATGTGTGCCTTCTTGTCAGCCAAGTTGACAATAAAGAGTAGCAAATTGT

hide sequence

RefSeq Acc Id:

XM_006235525 ⟹ XP_006235587

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	172,124,765 - 172,152,191 (+)	NCBI
mRatBN7.2	3	151,705,254 - 151,733,714 (+)	NCBI
Rnor_6.0	3	159,421,638 - 159,450,087 (+)	NCBI
Rnor_5.0	3	165,617,173 - 165,645,610 (+)	NCBI

Sequence:

show sequence

CGGGCGGCGCCGACGCACTTGGCGGGAGATAGGAAAGTGGTTCAGTGCGCTCCCTAGGCAGCTG
CAGTTCCTGGGAACGTGCGACAAGACCTGCAGACACGCTGACGCCTCAGAGCACCGCCTGGGGC
CCGGAGCGGCCGGTGCAGCCTGAGTCCTGACCCCGGCCCGGCTCCCGCTCCGGGCTCGGCCGGC
GGGCGTAAGGGCGCGGCGGGGTCCGGGCCGGGGGGATGTCTCGGCGGACGCGCTGTGAGGAACT
GGATGAGTTACGCTACCAGGACACGGACTCAGACCTCCTGGAGCAGAGAGACAACAAATGTAAG
GTCAAATGGACCCACGAGGAGGATGAGCTACTGAGGGCCCTGGTGAGGCAGTTTGGACAGCAAG
ACTGGAAGTTCCTGGCCAGTCACTTTCCTAACCGCACAGACCAGCAATGCCAGTACCGGTGGCT
GAGGGTTTTGAATCCAGACCTTGTTAAGGGACCGTGGACCAAAGAGGAAGATCAGAAGGTCATT
GAGCTGGTCAAGAAGTACGGCACAAAACAGTGGACGCTCATTGCCAAGCACCTGAAGGGCCGTC
TTGGGAAGCAGTGTCGTGAGCGCTGGCACAACCATCTCAACCCTGAGGTGAAGAAGTCCTGCTG
GACAGAGGAGGAAGATCGGATCATCTGTGAGGCCCATAAAGTGCTGGGCAACCGCTGGGCTGAG
ATCGCCAAGATGCTGCCAGGGAGGACAGACAATGCTGTGAAGAATCACTGGAATTCCACCATCA
AAAGGAAAGTCGACACGGGAGGGTTCCCAAACGAGTCCAGAGACTGCAAGCCTGTCTACTTGCT
CTTGGAGCTCGAGGACAAGGATTACCAACAGAATGTCCAGCCTGTGGAAGGCCCGGGAAGTCTT
GTGAGCAGCTGGCCCCTGGCGCCCTCTACTGTGAAGGAGGAGGAGAGCAGCGAGGAGGAGGCTG
CCGTGGCTACTACTTCTAAGGAACACAAGCAGGAGCCCGTCCCCACTGATCTGGGGGAAGTGCG
CACCCCAGAGCCCCTGGAATTCCTCAAGCGTGAATACCAGGAGGAATCCTCCCCAGAAACAAGC
CTGCCCTACAAGTGGGTGGTGGAGGCCGCGAACCTCCTCATCCCTGCTGTGGAGTCCAGCCTCT
CCGAAGCTCTGGACTTGATCGAGTCGGACCCCGATGCTTGGTGTGACCTCAGTAAATTTGATCT
TCCTGAAGAACCGTCTGCAGAGGGCAGTGTCAACAGTAGCCCAGTGCAACTCCAGACACCGCAG
CAGCAGCAACAGCACCAGCAGGCACTGTCATTCCACCAGGCTGCCACACCAGGGCCCAGTGTGA
CTGAGTATCGCCTTGATGGCCACACTATTTCAGACCTGAGCCGGAGCAGCCGGGGAGAGCTGAT
CCCCATTTCCCCAAGCACTGAGTTTGGGGGCTCAGGCATTGGCACACCGCCCTCAGTGCTCAAG
CGACAGAAGAAACGGCGCGTGGCCCTGTCGCCTGTCACAGAGAACAGTGCCAGCTTGTCCTTCC
TGGACTCCTGTAATAGCCTTACCCCGAAGAGCACACCTGTCAAAACCCTTCCCTTCTCTCCTTC
CCAGTTTCTGAACTTCTGGAACAAACAGGATACCCTGGAGTTGGAGAGCCCCTCCCTGACGTCC
ACTCCGGTGTGCAGCCAAAAGGTGGTAGTCACCACACCCTTGCACAGGGATAAGACGCCCCTGC
ACCAGAAGTATCCATCCAGGTTTGTAACCCCAGATCAGAAGTATTCCATGGACAACACTCCCCA
CACACCAACCCCGTTCAAGAATGCTCTGGAGAAATATGGACCACTGAAACCCCTGCCCCAAACC
CCACACCTGGAAGAGGACTTGAAGGAGGTGCTTCGTTCCGAGGCTGGCATTGAGCTCATCATTG
AGGATGACATGAGACCCGAGAAACAGAAGAGAAAGCCTGGGCTCCGGCGAAGCCCTATCAAGAA
GGTTCGGAAGTCTCTGGCTCTTGACATTGTGGATGAGGATGGGAAGATGATGTCATCGACCTCG
CCCAAGACTCTGTCCTTGCCAACCAGTGTCCCATCCAGCTCCTCTGGCTTCATCTTGCCGGGTA
TCAAGGAGGATAACAGCCTGCTCAACCAGGGCTTCCTACAGGCCAAACCCGAGAAGGTGGTGGC
CACCCAGAAGCCCCGGAGCCACATTCCAGCCCCTGCTCCTATGACCCGTGCCTGGAAGACGGTG
GCCTGTGGGGGCACTAAAGACCAGCTCTTCATGCAAGAGAAGGCCCGGCAGCTCCTGGGCCGTC
TGAAGTCCAGCCACACATCTCGGACCCTCATTCTGTCCTGAGGGGCTTGCAGGGAACAAGCCAG
CTCTCATGTTTACAGGGGTAGGGTGTGGGGTAAGGTGTGCGTTGAAGTCACATTAAATGACCAG
CTTCAGGAAGTCTTCTGCCAGCCCCTCAGTCTGCTCAGGTGGCAGAAGTCACATGGTACATCTC
TTCCCCCGGTCTAGCCTTTGTGAAGTTCCTGGTGGTGCTAATAGAACAAAGTCCCACTCCTGGG
CCTGCCTGCCCTCCGCCCAGTGCCACAAGGAGCCCTATTAGGTTCTCCCAGGCTCTCATCCAGA
CTCCTGCTTAGGATGGGGGTGTGGCGAGGGGTGCTCCTTCCCTCGTTTGTTGGTACACTGTCTC
CACAATAAAATACCGTTCTCCCTATGCAGCCCCGACTCTGCCCTCTGAGTCTTGAAGTGCCTTG
AAGGCCCTCTCCTGACACGTAGGCCTGTAGACCTCTGTTCTTGGGTACAGCTTTACCCAGTGAG
CATCTCTGCAAAGCTCCCAAGAGCTCTGAGTGGATGAAGATGGGTTCTGAGAACCTGTTAGAAC
GGTGTATTCACCTTTGCCCTGATGCCTCAGGGCCATGGCTTGGGGCATGGGTGGTTCTTATGGC
TTCCACGGAGCAGCTGCTGCCTTAAGCCGAGCCTGCCATAGGTAAGACCATTAATATAGGTAGA
GGGATGGATGGCAGGCCTTTCGACTCTGGCCAATGTGTGGAAGGCTGCCCAGCTCCTGGATCTT
TTATCCTGAATTGGTGGCAGCCATGGCCTGGGCTGTCACCTCCCTTGGAGTCAGTGGGTAGAGC
GTGGTCCATAGTTCAGTCAGTTAAGAGCTTGACTAGGGAGATGCTGAGCCTAATGTCTACGTTA
GGAAGTGTTGTTTTCTGTAGCCTGCCTGGGTGTCCCTGGGTTGGGAGTTAGATGGACCTATGGG
AGGTCTAGACTTAGTCCTGGTTAAAGGGAGACTTGAGGCAAATGTTCTCCAACTGGGCAAGAGA
TAACGTCTGAAGAAGACTGCGCTAGCACACCGGAGTCCAGGCGCTCTCCTGTAAAAGATACGGG
AGCCGGGCTGTGCTCTCACACTGTGCCTACTGCAGCCTCCTTGTCTGAGCCCCATGCTCAGTGA
GCAGCACCTGCCTCACCCCTGGCTCTCTAGTTCTTTTCTCAGAATGGCTAAGGCGACTAGCAGC
CACGCGTGTGTGCGGTCTGTGCTTGAGAAGGCATGGTGGAGGACAGGCTGTCAAGCAGAGGATA
AAGGCTGCTGGTGCCTACCAGGCTCTCCTACAGTCGGGGCTCTCTAAGGGGTGCCGCAGCCTGC
ATTTAGGGGGGCTCTTTTAACCCTGGAATTTCCTCATAGACACACGCAAATGTGTGCCTTCTTG
TCAGCCAAGTTGACAATAAAGAGTAGCAAATTGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100006	(Get FASTA)	NCBI Sequence Viewer
	NP_001417114	(Get FASTA)	NCBI Sequence Viewer
	XP_006235587	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL96595	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010343
	ENSRNOP00000010343.6
	ENSRNOP00000103500.1
	ENSRNOP00000106433
	ENSRNOP00000106433.1

RefSeq Acc Id:

NP_001100006 ⟸ NM_001106536

- UniProtKB:

D3ZLC6 (UniProtKB/TrEMBL), A6JX14 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRRTRCEELDELRYQDTDSDLLEQRDNKCKVKWTHEEDELLRALVRQFGQQDWKFLASHFPNR
TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNH
LNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPNE
SRDCKPVYLLLELEDKDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQE
PVPTDLGEVRTPEPLEFLKREYQEESSPETSLPYKWVVEAANLLIPAVESSLSEALDLIESDPD
AWCDLSKFDLPEEPSAEGSVNSSPVQLQTPQQQQQHQQALSFHQAATPGPSVTEYRLDGHTISD
LSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKST
PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSFVTPDQ
KYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIIEDDMRPEKQKRKP
GLRRSPIKKVRKSLALDIVDEDGKMMSSTSPKTLSLPTSVPSSSSGFILPGIKEDNSLLNQGFL
QAKPEKVVATQKPRSHIPAPAPMTRAWKTVACGGTKDQLFMQEKARQLLGRLKSSHTSRTLILS

hide sequence

RefSeq Acc Id:

XP_006235587 ⟸ XM_006235525

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSRRTRCEELDELRYQDTDSDLLEQRDNKCKVKWTHEEDELLRALVRQFGQQDWKFLASHFPNR
TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNH
LNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPNE
SRDCKPVYLLLELEDKDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQE
PVPTDLGEVRTPEPLEFLKREYQEESSPETSLPYKWVVEAANLLIPAVESSLSEALDLIESDPD
AWCDLSKFDLPEEPSAEGSVNSSPVQLQTPQQQQQHQQALSFHQAATPGPSVTEYRLDGHTISD
LSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKST
PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSRFVTPD
QKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIIEDDMRPEKQKRK
PGLRRSPIKKVRKSLALDIVDEDGKMMSSTSPKTLSLPTSVPSSSSGFILPGIKEDNSLLNQGF
LQAKPEKVVATQKPRSHIPAPAPMTRAWKTVACGGTKDQLFMQEKARQLLGRLKSSHTSRTLIL
S

hide sequence

Ensembl Acc Id:

ENSRNOP00000010343 ⟸ ENSRNOT00000010343

Ensembl Acc Id:

ENSRNOP00000106433 ⟸ ENSRNOT00000128666

Ensembl Acc Id:

ENSRNOP00000103500 ⟸ ENSRNOT00000149485

Protein Domains

HTH myb-type Myb-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZLC6-F1-model_v2	AlphaFold	D3ZLC6	1-704	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692632

Promoter ID:

EPDNEW_R3155

Type:

initiation region

Name:

Mybl2_1

Description:

MYB proto-oncogene like 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	159,421,703 - 159,421,763	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308474	AgrOrtholog
BioCyc Gene	G2FUF-46922	BioCyc
Ensembl Genes	ENSRNOG00000007805	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010343	ENTREZGENE
	ENSRNOT00000010343.8	UniProtKB/TrEMBL
	ENSRNOT00000128666	ENTREZGENE
	ENSRNOT00000128666.1	UniProtKB/TrEMBL
	ENSRNOT00000149485.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	C-myb_C	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	HTH_Myb-type_DNA-bd	UniProtKB/TrEMBL
	MYB_TF	UniProtKB/TrEMBL
	SANT_DNA-bd	UniProtKB/TrEMBL
KEGG Report	rno:296344	UniProtKB/TrEMBL
NCBI Gene	296344	ENTREZGENE
PANTHER	MYB PROTEIN-RELATED	UniProtKB/TrEMBL
	MYB-LIKE DNA-BINDING PROTEIN BAS1	UniProtKB/TrEMBL
Pfam	Cmyb_C	UniProtKB/TrEMBL
	Myb_DNA-bind_6	UniProtKB/TrEMBL
	Myb_DNA-binding	UniProtKB/TrEMBL
PhenoGen	Mybl2	PhenoGen
PROSITE	HTH_MYB	UniProtKB/TrEMBL
	MYB_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007805	RatGTEx
SMART	SANT	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A0ABK0L862_RAT	UniProtKB/TrEMBL
	A0ABK0LKK8_RAT	UniProtKB/TrEMBL
	A6JX14	ENTREZGENE, UniProtKB/TrEMBL
	D3ZLC6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-29	Mybl2	MYB proto-oncogene like 2	Mybl2	myeloblastosis oncogene-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Mybl2	myeloblastosis oncogene-like 2	Mybl2_predicted	myeloblastosis oncogene-like 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Mybl2_predicted	myeloblastosis oncogene-like 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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