Fbxo46 (F-box protein 46) - Rat Genome Database

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Gene: Fbxo46 (F-box protein 46) Rattus norvegicus
Analyze
Symbol: Fbxo46
Name: F-box protein 46
RGD ID: 1308393
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO46 (F-box protein 46); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: F-box only protein 46; LOC292686; MGC114545
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,898,029 - 87,914,615 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl187,897,888 - 87,926,021 (+)EnsemblGRCr8
mRatBN7.2178,770,059 - 78,786,582 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,770,018 - 78,790,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,159,152 - 84,175,617 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,716,827 - 92,733,257 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,914,254 - 85,930,719 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,028,873 - 80,045,666 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,028,928 - 80,045,341 (+)Ensemblrn6Rnor6.0
Rnor_5.0181,296,252 - 81,312,729 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,480,914 - 78,497,104 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,235,831 - 73,252,251 (+)NCBICelera
RGSC_v3.1178,559,024 - 78,575,215 (+)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Fbxo46
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,898,029 - 87,914,615 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl187,897,888 - 87,926,021 (+)EnsemblGRCr8
mRatBN7.2178,770,059 - 78,786,582 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,770,018 - 78,790,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,159,152 - 84,175,617 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,716,827 - 92,733,257 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,914,254 - 85,930,719 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,028,873 - 80,045,666 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,028,928 - 80,045,341 (+)Ensemblrn6Rnor6.0
Rnor_5.0181,296,252 - 81,312,729 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,480,914 - 78,497,104 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,235,831 - 73,252,251 (+)NCBICelera
RGSC_v3.1178,559,024 - 78,575,215 (+)NCBI
Cytogenetic Map1q21NCBI
FBXO46
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,710,629 - 45,733,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,710,624 - 45,730,919 (-)Ensemblhg38GRCh38
GRCh371946,213,887 - 46,236,435 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,905,727 - 50,925,991 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1943,020,015 - 43,040,278 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,642,747 - 42,663,036 (-)NCBIHuRef
CHM1_11946,217,358 - 46,237,620 (-)NCBICHM1_1
T2T-CHM13v2.01948,538,171 - 48,560,723 (-)NCBIT2T-CHM13v2.0
Fbxo46
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,853,784 - 18,872,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,853,784 - 18,874,097 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38719,119,859 - 19,138,261 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,119,859 - 19,140,172 (+)Ensemblmm10GRCm38
MGSCv37719,705,208 - 19,723,610 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36718,278,392 - 18,296,777 (+)NCBIMGSCv36mm8
Celera716,531,201 - 16,549,614 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Fbxo46
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574177,374 - 182,143 (-)Ensembl
ChiLan1.0NW_004955574177,374 - 191,720 (-)NCBIChiLan1.0ChiLan1.0
FBXO46
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,871,738 - 51,892,083 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,743,186 - 53,763,518 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,715,616 - 42,735,949 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,252,675 - 51,273,444 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,253,737 - 51,255,548 (-)EnsemblpanPan2panpan1.1
FBXO46
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,863,907 - 109,878,908 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,875,994 - 109,877,847 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1109,349,088 - 109,364,060 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01110,397,172 - 110,412,167 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,397,239 - 110,412,643 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,072,790 - 110,087,733 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,707,441 - 109,722,373 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,576,252 - 110,591,238 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbxo46
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,733,396 - 17,748,077 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,081,780 - 2,083,591 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,080,744 - 2,095,350 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO46
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,053,281 - 52,069,166 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1652,053,277 - 52,069,190 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FBXO46
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,152,174 - 39,175,059 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,152,840 - 39,154,651 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607318,781,689 - 18,805,008 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo46
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,473,719 - 7,475,557 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248327,461,768 - 7,476,571 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbxo46
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12171,484,741 - 171,500,807 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbxo46
129 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:83
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000012082
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
AW532124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,785,828 - 78,786,002 (+)MAPPERmRatBN7.2
Rnor_6.0180,044,596 - 80,044,769NCBIRnor6.0
Rnor_5.0181,311,976 - 81,312,149UniSTSRnor5.0
RGSC_v3.4178,496,582 - 78,496,755UniSTSRGSC3.4
Celera173,251,500 - 73,251,673UniSTS
RH 3.4 Map1789.0UniSTS
Cytogenetic Map1q21UniSTS
BF393720  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,786,805 - 78,786,956 (+)MAPPERmRatBN7.2
Rnor_6.0180,045,573 - 80,045,723NCBIRnor6.0
Rnor_5.0181,312,953 - 81,313,103UniSTSRnor5.0
RGSC_v3.4178,497,386 - 78,497,536UniSTSRGSC3.4
Celera173,252,477 - 73,252,627UniSTS
RH 3.4 Map1789.1UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012082   ⟹   ENSRNOP00000012082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,907,942 - 87,924,143 (+)Ensembl
mRatBN7.2 Ensembl178,770,097 - 78,790,097 (+)Ensembl
Rnor_6.0 Ensembl180,028,928 - 80,045,341 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111723   ⟹   ENSRNOP00000081250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,770,112 - 78,790,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115550   ⟹   ENSRNOP00000090659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,188 - 87,924,143 (+)Ensembl
mRatBN7.2 Ensembl178,780,355 - 78,790,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118710   ⟹   ENSRNOP00000079832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,897,888 - 87,916,122 (+)Ensembl
mRatBN7.2 Ensembl178,770,018 - 78,790,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119270   ⟹   ENSRNOP00000097011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,908,254 - 87,926,021 (+)Ensembl
mRatBN7.2 Ensembl178,780,355 - 78,790,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000122695   ⟹   ENSRNOP00000104882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,046 - 87,926,021 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139630   ⟹   ENSRNOP00000103398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,119 - 87,922,772 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155506   ⟹   ENSRNOP00000104645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,174 - 87,924,143 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162291   ⟹   ENSRNOP00000099991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,908,158 - 87,926,021 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166640   ⟹   ENSRNOP00000103091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,056 - 87,926,021 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000171860   ⟹   ENSRNOP00000112051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl187,898,169 - 87,926,021 (+)Ensembl
RefSeq Acc Id: NM_001025642   ⟹   NP_001020813
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,898,194 - 87,914,615 (+)NCBI
mRatBN7.2178,770,156 - 78,786,580 (+)NCBI
Rnor_6.0180,028,928 - 80,045,347 (+)NCBI
Rnor_5.0181,296,252 - 81,312,729 (+)NCBI
RGSC_v3.4178,480,914 - 78,497,104 (+)RGD
Celera173,235,831 - 73,252,251 (+)RGD
Sequence:
RefSeq Acc Id: XM_006228399   ⟹   XP_006228461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,898,029 - 87,914,615 (+)NCBI
mRatBN7.2178,770,059 - 78,786,582 (+)NCBI
Rnor_6.0180,028,873 - 80,045,666 (+)NCBI
Rnor_5.0181,296,252 - 81,312,729 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228400   ⟹   XP_006228462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,907,748 - 87,914,615 (+)NCBI
mRatBN7.2178,779,710 - 78,786,582 (+)NCBI
Rnor_6.0180,038,479 - 80,045,666 (+)NCBI
Rnor_5.0181,296,252 - 81,312,729 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228401   ⟹   XP_006228463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,907,748 - 87,914,615 (+)NCBI
mRatBN7.2178,779,710 - 78,786,582 (+)NCBI
Rnor_6.0180,038,479 - 80,045,666 (+)NCBI
Rnor_5.0181,296,252 - 81,312,729 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103955   ⟹   XP_038959883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,898,082 - 87,914,615 (+)NCBI
mRatBN7.2178,770,059 - 78,786,582 (+)NCBI
RefSeq Acc Id: XM_039103964   ⟹   XP_038959892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,898,088 - 87,914,615 (+)NCBI
mRatBN7.2178,770,174 - 78,786,582 (+)NCBI
RefSeq Acc Id: NP_001020813   ⟸   NM_001025642
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228461   ⟸   XM_006228399
- Peptide Label: isoform X1
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228462   ⟸   XM_006228400
- Peptide Label: isoform X1
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228463   ⟸   XM_006228401
- Peptide Label: isoform X1
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012082   ⟸   ENSRNOT00000012082
RefSeq Acc Id: XP_038959883   ⟸   XM_039103955
- Peptide Label: isoform X1
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959892   ⟸   XM_039103964
- Peptide Label: isoform X1
- UniProtKB: Q4KLY2 (UniProtKB/Swiss-Prot),   A6J8J9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090659   ⟸   ENSRNOT00000115550
Ensembl Acc Id: ENSRNOP00000079832   ⟸   ENSRNOT00000118710
Ensembl Acc Id: ENSRNOP00000097011   ⟸   ENSRNOT00000119270
Ensembl Acc Id: ENSRNOP00000081250   ⟸   ENSRNOT00000111723
Ensembl Acc Id: ENSRNOP00000103091   ⟸   ENSRNOT00000166640
Ensembl Acc Id: ENSRNOP00000104882   ⟸   ENSRNOT00000122695
Ensembl Acc Id: ENSRNOP00000104645   ⟸   ENSRNOT00000155506
Ensembl Acc Id: ENSRNOP00000099991   ⟸   ENSRNOT00000162291
Ensembl Acc Id: ENSRNOP00000103398   ⟸   ENSRNOT00000139630
Ensembl Acc Id: ENSRNOP00000112051   ⟸   ENSRNOT00000171860
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLY2-F1-model_v2 AlphaFold Q4KLY2 1-603 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689761
Promoter ID:EPDNEW_R285
Type:initiation region
Name:Fbxo46_1
Description:F-box protein 46
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,028,935 - 80,028,995EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308393 AgrOrtholog
BioCyc Gene G2FUF-60530 BioCyc
Ensembl Genes ENSRNOG00000008815 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012082.5 UniProtKB/Swiss-Prot
  ENSRNOT00000111723.1 UniProtKB/Swiss-Prot
  ENSRNOT00000115550.1 UniProtKB/Swiss-Prot
  ENSRNOT00000118710.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119270 ENTREZGENE
  ENSRNOT00000119270.1 UniProtKB/Swiss-Prot
  ENSRNOT00000122695 ENTREZGENE
  ENSRNOT00000139630 ENTREZGENE
  ENSRNOT00000155506 ENTREZGENE
  ENSRNOT00000162291 ENTREZGENE
  ENSRNOT00000171860 ENTREZGENE
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7458607 IMAGE-MGC_LOAD
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot
  F-box_dom UniProtKB/Swiss-Prot
  FBXO34/46 UniProtKB/Swiss-Prot
KEGG Report rno:292686 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114545 IMAGE-MGC_LOAD
NCBI Gene 292686 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 46 UniProtKB/Swiss-Prot
  PTHR16271 UniProtKB/Swiss-Prot
Pfam F-box-like UniProtKB/Swiss-Prot
PhenoGen Fbxo46 PhenoGen
PROSITE FBOX UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008815 RatGTEx
SMART FBOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF81383 UniProtKB/Swiss-Prot
UniProt A6J8J9 ENTREZGENE, UniProtKB/TrEMBL
  FBX46_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Fbxo46  F-box protein 46  Fbxo46_predicted  F-box protein 46 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fbxo46_predicted  F-box protein 46 (predicted)      Symbol and Name status set to approved 70820 APPROVED