Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Serinc3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SERINC3 mRNA | CTD | PMID:36331819 | Serinc3 | Rat | (S)-nicotine | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of SERINC3 mRNA | CTD | PMID:16949557 | Serinc3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SERINC3 mRNA | CTD | PMID:22206623 | Serinc3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of SERINC3 mRNA | CTD | PMID:22206623 | Serinc3 | Rat | 17beta-estradiol | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Estradiol results in increased expression of SERINC3 mRNA | CTD | PMID:22467019 | Serinc3 | Rat | 17beta-estradiol | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Estradiol results in decreased expression of SERINC3 mRNA | CTD | PMID:39298647 | Serinc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SERINC3 mRNA | CTD | PMID:19770486 | Serinc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SERINC3 mRNA | CTD | PMID:32109520|PMID:34747641 | Serinc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Serinc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SERINC3 mRNA | CTD | PMID:21570461 | Serinc3 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of SERINC3 mRNA | CTD | PMID:21346803 | Serinc3 | Rat | 2-butoxyethanol | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of SERINC3 mRNA | CTD | PMID:19812364 | Serinc3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Serinc3 | Rat | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of SERINC3 mRNA | CTD | PMID:19162173 | Serinc3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of SERINC3 mRNA | CTD | PMID:18648102 | Serinc3 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | Serinc3 (Mus musculus) | 6480464 | bisphenol S affects the expression of SERINC3 mRNA | CTD | PMID:39298647 | Serinc3 | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | acrolein | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Serinc3 | Rat | aflatoxin B1 | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of SERINC3 mRNA | CTD | PMID:19770486 | Serinc3 | Rat | alpha-pinene | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Serinc3 | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | Aroclor 1254 | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of SERINC3 mRNA | CTD | PMID:23650126 | Serinc3 | Rat | arsane | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Arsenic results in decreased expression of SERINC3 mRNA | CTD | PMID:19654921 | Serinc3 | Rat | arsenic atom | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Arsenic results in decreased expression of SERINC3 mRNA | CTD | PMID:19654921 | Serinc3 | Rat | asbestos | affects expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Asbestos affects the expression of SERINC3 mRNA | CTD | PMID:17297452 | Serinc3 | Rat | azathioprine | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Azathioprine results in increased expression of SERINC3 mRNA | CTD | PMID:21621594 | Serinc3 | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | benzo[a]pyrene | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SERINC3 mRNA | CTD | PMID:19770486 | Serinc3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SERINC3 mRNA | CTD | PMID:20018196 | Serinc3 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of SERINC3 mRNA | CTD | PMID:33754040 | Serinc3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SERINC3 mRNA | CTD | PMID:25181051|PMID:33296240 | Serinc3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SERINC3 mRNA | CTD | PMID:30816183|PMID:32528016|PMID:34947998 | Serinc3 | Rat | bisphenol F | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Serinc3 | Rat | bisphenol F | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | bisphenol F results in increased expression of SERINC3 mRNA | CTD | PMID:38685157 | Serinc3 | Rat | cadmium atom | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERINC3 more ... | CTD | PMID:37236586 | Serinc3 | Rat | cadmium dichloride | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERINC3 more ... | CTD | PMID:37236586 | Serinc3 | Rat | caffeine | increases phosphorylation | ISO | SERINC3 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of SERINC3 protein | CTD | PMID:35688186 | Serinc3 | Rat | carbon nanotube | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of SERINC3 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681|PMID:25620056 | Serinc3 | Rat | chloroprene | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Chloroprene results in increased expression of SERINC3 mRNA | CTD | PMID:23125180 | Serinc3 | Rat | ciguatoxin CTX1B | affects expression | ISO | Serinc3 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of SERINC3 mRNA | CTD | PMID:18353800 | Serinc3 | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | copper atom | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression more ... | CTD | PMID:15467011 | Serinc3 | Rat | copper(0) | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression more ... | CTD | PMID:15467011 | Serinc3 | Rat | cyclosporin A | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of SERINC3 mRNA | CTD | PMID:19770486|PMID:21621594 | Serinc3 | Rat | dexamethasone | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of SERINC3 mRNA | CTD | PMID:21621594 | Serinc3 | Rat | dexamethasone | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Serinc3 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of SERINC3 mRNA | CTD | PMID:21266533 | Serinc3 | Rat | dibutyl phthalate | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SERINC3 mRNA | CTD | PMID:17361019|PMID:21266533 | Serinc3 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of SERINC3 mRNA | CTD | PMID:22546817 | Serinc3 | Rat | dioxygen | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of SERINC3 mRNA | CTD | PMID:22629407 | Serinc3 | Rat | dioxygen | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of SERINC3 mRNA] | CTD | PMID:22629407 | Serinc3 | Rat | disodium selenite | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SERINC3 mRNA | CTD | PMID:18175754 | Serinc3 | Rat | doxorubicin | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of SERINC3 mRNA | CTD | PMID:16243910|PMID:25896364|PMID:39631538 | Serinc3 | Rat | doxorubicin | decreases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SERINC3 mRNA | CTD | PMID:29803840 | Serinc3 | Rat | ethanol | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of SERINC3 mRNA | CTD | PMID:30319688 | Serinc3 | Rat | fenthion | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SERINC3 mRNA | CTD | PMID:34813904 | Serinc3 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of SERINC3 mRNA | CTD | PMID:24136188 | Serinc3 | Rat | folic acid | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SERINC3 mRNA | CTD | PMID:22206623 | Serinc3 | Rat | formaldehyde | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of SERINC3 mRNA | CTD | PMID:23649840 | Serinc3 | Rat | FR900359 | decreases phosphorylation | ISO | SERINC3 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SERINC3 protein | CTD | PMID:37730182 | Serinc3 | Rat | fumonisin B1 | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | fumonisin B1 results in increased expression of SERINC3 mRNA | CTD | PMID:16221962 | Serinc3 | Rat | gamma-hexachlorocyclohexane | affects expression | EXP | | 6480464 | Hexachlorocyclohexane affects the expression of SERINC3 mRNA | CTD | PMID:17785943 | Serinc3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SERINC3 mRNA | CTD | PMID:22061828 | Serinc3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SERINC3 mRNA | CTD | PMID:33387578 | Serinc3 | Rat | glycidyl methacrylate | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | glycidyl methacrylate results in increased expression of SERINC3 protein | CTD | PMID:36641056 | Serinc3 | Rat | indometacin | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Serinc3 | Rat | isoprenaline | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of SERINC3 mRNA | CTD | PMID:20003209 | Serinc3 | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | lead(0) | affects expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Lead affects the expression of SERINC3 mRNA | CTD | PMID:28903495 | Serinc3 | Rat | methidathion | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | methidathion results in decreased expression of SERINC3 mRNA | CTD | PMID:34813904 | Serinc3 | Rat | methotrexate | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Methotrexate results in increased expression of SERINC3 mRNA | CTD | PMID:21621594 | Serinc3 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of SERINC3 mRNA | CTD | PMID:22546817 | Serinc3 | Rat | nicotine | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of SERINC3 mRNA | CTD | PMID:16949557 | Serinc3 | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | ozone | multiple interactions | ISO | SERINC3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268|PMID:35430440 | Serinc3 | Rat | ozone | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Serinc3 | Rat | paracetamol | affects expression | ISO | Serinc3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SERINC3 mRNA | CTD | PMID:17562736 | Serinc3 | Rat | paracetamol | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SERINC3 mRNA | CTD | PMID:22230336 | Serinc3 | Rat | paraquat | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Paraquat results in increased expression of SERINC3 mRNA | CTD | PMID:12595580 | Serinc3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SERINC3 mRNA | CTD | PMID:36331819 | Serinc3 | Rat | pirinixic acid | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SERINC3 mRNA | CTD | PMID:18445702 | Serinc3 | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of SERINC3 mRNA | CTD | PMID:28903501 | Serinc3 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SERINC3 mRNA | CTD | PMID:28374803 | Serinc3 | Rat | sodium arsenate | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SERINC3 mRNA | CTD | PMID:39847705 | Serinc3 | Rat | sodium arsenite | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SERINC3 mRNA | CTD | PMID:38568856 | Serinc3 | Rat | sodium arsenite | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of SERINC3 mRNA | CTD | PMID:36209798 | Serinc3 | Rat | sodium dodecyl sulfate | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of SERINC3 mRNA | CTD | PMID:21621594 | Serinc3 | Rat | succimer | multiple interactions | ISO | Serinc3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SERINC3 mRNA | CTD | PMID:21641980 | Serinc3 | Rat | tacrolimus hydrate | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Tacrolimus results in decreased expression of SERINC3 mRNA | CTD | PMID:21621594 | Serinc3 | Rat | testosterone | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Testosterone results in increased expression of SERINC3 mRNA | CTD | PMID:20403060 | Serinc3 | Rat | testosterone | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of SERINC3 mRNA | CTD | PMID:33848595 | Serinc3 | Rat | tetrachloromethane | affects expression | ISO | Serinc3 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of SERINC3 mRNA | CTD | PMID:17484886 | Serinc3 | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of SERINC3 mRNA | CTD | PMID:19483382 | Serinc3 | Rat | titanium dioxide | increases expression | ISO | Serinc3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SERINC3 mRNA | CTD | PMID:23131501 | Serinc3 | Rat | troglitazone | decreases expression | ISO | Serinc3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SERINC3 mRNA | CTD | PMID:17569031 | Serinc3 | Rat | urethane | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Urethane results in increased expression of SERINC3 mRNA | CTD | PMID:28818685 | Serinc3 | Rat | vitamin E | increases expression | ISO | SERINC3 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of SERINC3 mRNA | CTD | PMID:19244175 | | |||||||||





















