Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1) - Rat Genome Database

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Gene: Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1) Rattus norvegicus
Analyze
Symbol: Raph1
Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RGD ID: 1308387
Description: Predicted to be involved in signal transduction. Predicted to act upstream of or within axon extension. Predicted to be located in cell leading edge and nuclear body. Predicted to be active in cytosol and plasma membrane. Orthologous to human RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363239; ras-associated and pleckstrin homology domains-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8969,397,272 - 69,484,174 (-)NCBIGRCr8
mRatBN7.2961,907,476 - 61,990,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx970,411,407 - 70,492,233 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,526,986 - 75,607,814 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,845,679 - 73,926,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0967,290,004 - 67,370,208 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0967,104,292 - 67,184,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4959,083,429 - 59,165,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1959,237,947 - 59,320,248 (-)NCBI
Celera959,337,785 - 59,417,840 (-)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
ciguatoxin CTX1B  (ISO)
clobetasol  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
endosulfan  (EXP)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
iron dichloride  (ISO)
isoprenaline  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
testosterone  (ISO)
tetraphene  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell leading edge  (ISO)
cytosol  (IBA,ISO)
nuclear body  (IEA,ISO)
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:20417104  


Genomics

Comparative Map Data
Raph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8969,397,272 - 69,484,174 (-)NCBIGRCr8
mRatBN7.2961,907,476 - 61,990,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx970,411,407 - 70,492,233 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,526,986 - 75,607,814 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,845,679 - 73,926,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0967,290,004 - 67,370,208 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0967,104,292 - 67,184,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4959,083,429 - 59,165,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1959,237,947 - 59,320,248 (-)NCBI
Celera959,337,785 - 59,417,840 (-)NCBICelera
Cytogenetic Map9q32NCBI
RAPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382203,433,682 - 203,535,301 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2203,394,345 - 203,535,335 (-)EnsemblGRCh38hg38GRCh38
GRCh372204,298,405 - 204,400,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362204,006,783 - 204,108,303 (-)NCBINCBI36Build 36hg18NCBI36
Celera2198,053,361 - 198,154,883 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2196,146,067 - 196,207,516 (-)NCBIHuRef
CHM1_12204,305,122 - 204,406,629 (-)NCBICHM1_1
T2T-CHM13v2.02203,915,590 - 204,017,213 (-)NCBIT2T-CHM13v2.0
Raph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,509,997 - 60,606,233 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,521,451 - 60,606,263 (-)EnsemblGRCm39 Ensembl
GRCm38160,471,180 - 60,567,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl160,482,292 - 60,567,104 (-)EnsemblGRCm38mm10GRCm38
MGSCv37160,540,029 - 60,623,609 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36160,426,839 - 60,511,311 (-)NCBIMGSCv36mm8
Celera160,999,032 - 61,082,464 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.48NCBI
Raph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545711,394,572 - 11,462,617 (+)NCBIChiLan1.0ChiLan1.0
RAPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213106,037,158 - 106,141,217 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B106,052,152 - 106,153,555 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,664,717 - 90,766,088 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,805,254 - 208,865,624 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,765,847 - 208,865,624 (-)Ensemblpanpan1.1panPan2
RAPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13712,279,100 - 12,346,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3713,162,247 - 13,264,028 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03712,220,193 - 12,317,047 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3712,221,761 - 12,282,736 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13712,172,509 - 12,274,245 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03712,147,117 - 12,237,334 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03712,136,662 - 12,238,466 (-)NCBIUU_Cfam_GSD_1.0
Raph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303160,467,617 - 160,561,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936631108,310 - 196,563 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936631100,072 - 196,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115106,900,826 - 106,997,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215118,228,615 - 118,297,732 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11089,191,220 - 89,294,746 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1089,192,772 - 89,250,757 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040110,085,771 - 110,194,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Raph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476512,922,083 - 12,990,363 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476512,867,547 - 12,994,605 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Raph1
147 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:94
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000036194
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96138143465691299Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat

Markers in Region
BE098157  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,910,016 - 61,910,166 (+)MAPPERmRatBN7.2
Rnor_6.0967,290,528 - 67,290,677NCBIRnor6.0
Rnor_5.0967,104,816 - 67,104,965UniSTSRnor5.0
RGSC_v3.4959,085,765 - 59,085,914UniSTSRGSC3.4
Celera959,338,309 - 59,338,458UniSTS
RH 3.4 Map9506.2UniSTS
Cytogenetic Map9q31UniSTS
BF399918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,912,089 - 61,912,248 (+)MAPPERmRatBN7.2
Rnor_6.0967,292,601 - 67,292,759NCBIRnor6.0
Rnor_5.0967,106,889 - 67,107,047UniSTSRnor5.0
RGSC_v3.4959,087,838 - 59,087,996UniSTSRGSC3.4
Celera959,340,382 - 59,340,540UniSTS
RH 3.4 Map9503.8UniSTS
Cytogenetic Map9q31UniSTS
RH139062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,908,423 - 61,908,633 (+)MAPPERmRatBN7.2
Rnor_6.0967,288,935 - 67,289,144NCBIRnor6.0
Rnor_5.0967,103,223 - 67,103,432UniSTSRnor5.0
RGSC_v3.4959,084,142 - 59,084,351UniSTSRGSC3.4
Celera959,336,716 - 59,336,925UniSTS
RH 3.4 Map9503.5UniSTS
Cytogenetic Map9q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 36 27 24 8 24 1 1 66 20 32 11 1
Low 2 7 30 17 11 17 7 10 8 15 9 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000036194   ⟹   ENSRNOP00000033491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,915,418 - 61,961,209 (-)Ensembl
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102881   ⟹   ENSRNOP00000081933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103194   ⟹   ENSRNOP00000096832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106942   ⟹   ENSRNOP00000078550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110139   ⟹   ENSRNOP00000093050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119642   ⟹   ENSRNOP00000084951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
RefSeq Acc Id: NM_001108798   ⟹   NP_001102268
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,403,496 - 69,484,019 (-)NCBI
mRatBN7.2961,909,493 - 61,990,020 (-)NCBI
Rnor_6.0967,290,004 - 67,370,208 (-)NCBI
Rnor_5.0967,104,292 - 67,184,496 (-)NCBI
RGSC_v3.4959,083,429 - 59,165,764 (-)RGD
Celera959,337,785 - 59,417,840 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083861   ⟹   XP_038939789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,170 (-)NCBI
RefSeq Acc Id: XM_039083862   ⟹   XP_038939790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,169 (-)NCBI
RefSeq Acc Id: XM_039083863   ⟹   XP_038939791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,169 (-)NCBI
RefSeq Acc Id: XM_039083864   ⟹   XP_038939792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,455,051 (-)NCBI
mRatBN7.2961,907,711 - 61,961,049 (-)NCBI
RefSeq Acc Id: XM_039083866   ⟹   XP_038939794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,412,332 (-)NCBI
mRatBN7.2961,907,711 - 61,918,329 (-)NCBI
RefSeq Acc Id: XM_039083868   ⟹   XP_038939796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
mRatBN7.2961,907,489 - 61,990,166 (-)NCBI
RefSeq Acc Id: XM_039083869   ⟹   XP_038939797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,408,648 - 69,484,169 (-)NCBI
mRatBN7.2961,914,685 - 61,990,165 (-)NCBI
RefSeq Acc Id: XM_039083870   ⟹   XP_038939798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
mRatBN7.2961,907,476 - 61,990,165 (-)NCBI
RefSeq Acc Id: XM_063267379   ⟹   XP_063123449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,169 (-)NCBI
RefSeq Acc Id: XM_063267380   ⟹   XP_063123450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,166 (-)NCBI
RefSeq Acc Id: XM_063267381   ⟹   XP_063123451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
RefSeq Acc Id: XM_063267382   ⟹   XP_063123452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
RefSeq Acc Id: XR_005488933
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,731 - 61,990,170 (-)NCBI
RefSeq Acc Id: NP_001102268   ⟸   NM_001108798
- UniProtKB: A0A8I5ZU51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000033491   ⟸   ENSRNOT00000036194
RefSeq Acc Id: XP_038939798   ⟸   XM_039083870
- Peptide Label: isoform X9
- UniProtKB: A0A8I6AMM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939796   ⟸   XM_039083868
- Peptide Label: isoform X6
- UniProtKB: A6IPC9 (UniProtKB/TrEMBL),   A0A8I6AMM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939789   ⟸   XM_039083861
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A272 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939791   ⟸   XM_039083863
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZL54 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939790   ⟸   XM_039083862
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AF23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939792   ⟸   XM_039083864
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038939794   ⟸   XM_039083866
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038939797   ⟸   XM_039083869
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AMM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093050   ⟸   ENSRNOT00000110139
RefSeq Acc Id: ENSRNOP00000084951   ⟸   ENSRNOT00000119642
RefSeq Acc Id: ENSRNOP00000078550   ⟸   ENSRNOT00000106942
RefSeq Acc Id: ENSRNOP00000081933   ⟸   ENSRNOT00000102881
RefSeq Acc Id: ENSRNOP00000096832   ⟸   ENSRNOT00000103194
RefSeq Acc Id: XP_063123452   ⟸   XM_063267382
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063123451   ⟸   XM_063267381
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063123449   ⟸   XM_063267379
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063123450   ⟸   XM_063267380
- Peptide Label: isoform X10
Protein Domains
PH   Ras-associating

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADX8-F1-model_v2 AlphaFold D4ADX8 1-1265 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308387 AgrOrtholog
BioCyc Gene G2FUF-27379 BioCyc
Ensembl Genes ENSRNOG00000014722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036194.7 UniProtKB/TrEMBL
  ENSRNOT00000102881 ENTREZGENE
  ENSRNOT00000102881.1 UniProtKB/TrEMBL
  ENSRNOT00000103194.1 UniProtKB/TrEMBL
  ENSRNOT00000106942.1 UniProtKB/TrEMBL
  ENSRNOT00000110139.1 UniProtKB/TrEMBL
  ENSRNOT00000119642.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro GRB/APBB1IP UniProtKB/TrEMBL
  PH_APBB1IP UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras-assoc UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:363239 UniProtKB/TrEMBL
NCBI Gene 363239 ENTREZGENE
PANTHER PTHR11243 UniProtKB/TrEMBL
  RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
PharmGKB RAPH1 RGD
PhenoGen Raph1 PhenoGen
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014722 RatGTEx
SMART SM00233 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I5ZL54 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZU51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A272 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF23 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMM7 ENTREZGENE, UniProtKB/TrEMBL
  A6IPC9 ENTREZGENE, UniProtKB/TrEMBL
  D4ADX8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Raph1  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1   Raph1_predicted  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Raph1_predicted  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED