Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1) - Rat Genome Database

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Pathways
Gene: Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1) Rattus norvegicus
Analyze
Symbol: Raph1
Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RGD ID: 1308387
Description: Predicted to be involved in signal transduction. Predicted to act upstream of or within axon extension. Predicted to be located in cell leading edge. Predicted to be active in cytosol and plasma membrane. Orthologous to human RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363239; ras-associated and pleckstrin homology domains-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8969,397,272 - 69,484,174 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl969,401,517 - 69,484,019 (-)EnsemblGRCr8
mRatBN7.2961,907,476 - 61,990,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx970,411,407 - 70,492,233 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,526,986 - 75,607,814 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,845,679 - 73,926,405 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0967,290,004 - 67,370,208 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0967,104,292 - 67,184,496 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4959,083,429 - 59,165,764 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera959,337,785 - 59,417,840 (-)NCBICelera
RGSC_v3.1959,237,947 - 59,320,248 (-)NCBI
Cytogenetic Map9q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,6-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
ciguatoxin CTX1B  (ISO)
clobetasol  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
iron dichloride  (ISO)
isoprenaline  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
testosterone  (ISO)
tetraphene  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell leading edge  (IEA,ISO)
cytoskeleton  (IEA)
cytosol  (IBA,IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:20417104  


Genomics

Comparative Map Data
Raph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8969,397,272 - 69,484,174 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl969,401,517 - 69,484,019 (-)EnsemblGRCr8
mRatBN7.2961,907,476 - 61,990,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx970,411,407 - 70,492,233 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,526,986 - 75,607,814 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,845,679 - 73,926,405 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0967,290,004 - 67,370,208 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0967,104,292 - 67,184,496 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4959,083,429 - 59,165,764 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera959,337,785 - 59,417,840 (-)NCBICelera
RGSC_v3.1959,237,947 - 59,320,248 (-)NCBI
Cytogenetic Map9q32NCBI
RAPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382203,433,682 - 203,535,301 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2203,394,345 - 203,535,451 (-)Ensemblhg38GRCh38
GRCh372204,298,405 - 204,400,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362204,006,783 - 204,108,303 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2198,053,361 - 198,154,883 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2196,146,067 - 196,207,516 (-)NCBIHuRef
CHM1_12204,305,122 - 204,406,629 (-)NCBICHM1_1
T2T-CHM13v2.02203,915,590 - 204,017,213 (-)NCBIT2T-CHM13v2.0
Raph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,509,997 - 60,606,233 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,521,451 - 60,606,263 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38160,471,180 - 60,567,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl160,482,292 - 60,567,104 (-)Ensemblmm10GRCm38
MGSCv37160,540,029 - 60,623,609 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36160,426,839 - 60,511,311 (-)NCBIMGSCv36mm8
Celera160,999,032 - 61,082,464 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.48NCBI
Raph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545711,394,572 - 11,443,870 (+)Ensembl
ChiLan1.0NW_00495545711,394,572 - 11,462,617 (+)NCBIChiLan1.0ChiLan1.0
RAPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213106,037,158 - 106,141,217 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B106,052,152 - 106,153,555 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,664,717 - 90,766,088 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,805,254 - 208,865,624 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,765,847 - 208,865,624 (-)EnsemblpanPan2panpan1.1
RAPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13712,279,100 - 12,346,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3713,162,247 - 13,264,028 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03712,220,193 - 12,317,047 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3712,221,761 - 12,282,736 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13712,172,509 - 12,274,245 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03712,147,117 - 12,237,334 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03712,136,662 - 12,238,466 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Raph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303160,467,617 - 160,561,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936631108,310 - 196,563 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936631100,072 - 196,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115106,900,826 - 106,997,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215118,228,615 - 118,297,732 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11089,191,220 - 89,294,746 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1089,192,772 - 89,250,757 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040110,085,771 - 110,194,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Raph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476512,922,083 - 12,990,363 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476512,867,547 - 12,994,605 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Raph1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14134,602,830 - 134,676,935 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Raph1
691 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:94
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000036194
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96887549773185088Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
BE098157  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,910,016 - 61,910,166 (+)MAPPERmRatBN7.2
Rnor_6.0967,290,528 - 67,290,677NCBIRnor6.0
Rnor_5.0967,104,816 - 67,104,965UniSTSRnor5.0
RGSC_v3.4959,085,765 - 59,085,914UniSTSRGSC3.4
Celera959,338,309 - 59,338,458UniSTS
RH 3.4 Map9506.2UniSTS
Cytogenetic Map9q31UniSTS
BF399918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,912,089 - 61,912,248 (+)MAPPERmRatBN7.2
Rnor_6.0967,292,601 - 67,292,759NCBIRnor6.0
Rnor_5.0967,106,889 - 67,107,047UniSTSRnor5.0
RGSC_v3.4959,087,838 - 59,087,996UniSTSRGSC3.4
Celera959,340,382 - 59,340,540UniSTS
RH 3.4 Map9503.8UniSTS
Cytogenetic Map9q31UniSTS
RH139062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,908,423 - 61,908,633 (+)MAPPERmRatBN7.2
Rnor_6.0967,288,935 - 67,289,144NCBIRnor6.0
Rnor_5.0967,103,223 - 67,103,432UniSTSRnor5.0
RGSC_v3.4959,084,142 - 59,084,351UniSTSRGSC3.4
Celera959,336,716 - 59,336,925UniSTS
RH 3.4 Map9503.5UniSTS
Cytogenetic Map9q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000036194   ⟹   ENSRNOP00000033491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,401,517 - 69,455,152 (-)Ensembl
mRatBN7.2 Ensembl961,915,418 - 61,961,209 (-)Ensembl
Rnor_6.0 Ensembl967,293,309 - 67,341,341 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102881   ⟹   ENSRNOP00000081933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,403,509 - 69,482,043 (-)Ensembl
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103194   ⟹   ENSRNOP00000096832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,403,509 - 69,481,822 (-)Ensembl
mRatBN7.2 Ensembl961,907,758 - 61,961,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106942   ⟹   ENSRNOP00000078550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,403,509 - 69,455,152 (-)Ensembl
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110139   ⟹   ENSRNOP00000093050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,403,509 - 69,484,019 (-)Ensembl
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119642   ⟹   ENSRNOP00000084951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl969,403,509 - 69,455,152 (-)Ensembl
mRatBN7.2 Ensembl961,909,506 - 61,961,209 (-)Ensembl
RefSeq Acc Id: NM_001108798   ⟹   NP_001102268
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,403,496 - 69,484,019 (-)NCBI
mRatBN7.2961,909,493 - 61,990,020 (-)NCBI
Rnor_6.0967,290,004 - 67,370,208 (-)NCBI
Rnor_5.0967,104,292 - 67,184,496 (-)NCBI
RGSC_v3.4959,083,429 - 59,165,764 (-)RGD
Celera959,337,785 - 59,417,840 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083861   ⟹   XP_038939789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,170 (-)NCBI
RefSeq Acc Id: XM_039083862   ⟹   XP_038939790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,169 (-)NCBI
RefSeq Acc Id: XM_039083863   ⟹   XP_038939791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,711 - 61,990,169 (-)NCBI
RefSeq Acc Id: XM_039083864   ⟹   XP_038939792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,455,051 (-)NCBI
mRatBN7.2961,907,711 - 61,961,049 (-)NCBI
RefSeq Acc Id: XM_039083866   ⟹   XP_038939794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,412,332 (-)NCBI
mRatBN7.2961,907,711 - 61,918,329 (-)NCBI
RefSeq Acc Id: XM_039083868   ⟹   XP_038939796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
mRatBN7.2961,907,489 - 61,990,166 (-)NCBI
RefSeq Acc Id: XM_039083869   ⟹   XP_038939797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,408,648 - 69,484,169 (-)NCBI
mRatBN7.2961,914,685 - 61,990,165 (-)NCBI
RefSeq Acc Id: XM_039083870   ⟹   XP_038939798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
mRatBN7.2961,907,476 - 61,990,165 (-)NCBI
RefSeq Acc Id: XM_063267379   ⟹   XP_063123449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,169 (-)NCBI
RefSeq Acc Id: XM_063267380   ⟹   XP_063123450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,166 (-)NCBI
RefSeq Acc Id: XM_063267381   ⟹   XP_063123451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
RefSeq Acc Id: XM_063267382   ⟹   XP_063123452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,397,272 - 69,484,091 (-)NCBI
RefSeq Acc Id: XR_005488933
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8969,401,714 - 69,484,174 (-)NCBI
mRatBN7.2961,907,731 - 61,990,170 (-)NCBI
RefSeq Acc Id: NP_001102268   ⟸   NM_001108798
- UniProtKB: A0A8I5ZU51 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033491   ⟸   ENSRNOT00000036194
RefSeq Acc Id: XP_038939798   ⟸   XM_039083870
- Peptide Label: isoform X9
- UniProtKB: D4ADX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939796   ⟸   XM_039083868
- Peptide Label: isoform X6
- UniProtKB: A6IPC9 (UniProtKB/TrEMBL),   A0A8I6AMM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939789   ⟸   XM_039083861
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A272 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939791   ⟸   XM_039083863
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZL54 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939790   ⟸   XM_039083862
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AF23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939792   ⟸   XM_039083864
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038939794   ⟸   XM_039083866
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038939797   ⟸   XM_039083869
- Peptide Label: isoform X7
- UniProtKB: D4ADX8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093050   ⟸   ENSRNOT00000110139
Ensembl Acc Id: ENSRNOP00000084951   ⟸   ENSRNOT00000119642
Ensembl Acc Id: ENSRNOP00000078550   ⟸   ENSRNOT00000106942
Ensembl Acc Id: ENSRNOP00000081933   ⟸   ENSRNOT00000102881
Ensembl Acc Id: ENSRNOP00000096832   ⟸   ENSRNOT00000103194
RefSeq Acc Id: XP_063123452   ⟸   XM_063267382
- Peptide Label: isoform X12
- UniProtKB: A6IPD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123451   ⟸   XM_063267381
- Peptide Label: isoform X11
- UniProtKB: D4ADX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123449   ⟸   XM_063267379
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AMM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123450   ⟸   XM_063267380
- Peptide Label: isoform X10
- UniProtKB: A0A8I6AMM7 (UniProtKB/TrEMBL)
Protein Domains
PH   Ras-associating

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADX8-F1-model_v2 AlphaFold D4ADX8 1-1265 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308387 AgrOrtholog
BioCyc Gene G2FUF-27379 BioCyc
Ensembl Genes ENSRNOG00000014722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036194 ENTREZGENE
  ENSRNOT00000036194.8 UniProtKB/TrEMBL
  ENSRNOT00000102881 ENTREZGENE
  ENSRNOT00000102881.2 UniProtKB/TrEMBL
  ENSRNOT00000103194.2 UniProtKB/TrEMBL
  ENSRNOT00000106942 ENTREZGENE
  ENSRNOT00000106942.2 UniProtKB/TrEMBL
  ENSRNOT00000110139 ENTREZGENE
  ENSRNOT00000110139.2 UniProtKB/TrEMBL
  ENSRNOT00000119642 ENTREZGENE
  ENSRNOT00000119642.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro GRB/APBB1IP UniProtKB/TrEMBL
  PH_APBB1IP UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras-assoc UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:363239 UniProtKB/TrEMBL
NCBI Gene 363239 ENTREZGENE
PANTHER PTHR11243 UniProtKB/TrEMBL
  RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RA_2 UniProtKB/TrEMBL
PharmGKB RAPH1 RGD
PhenoGen Raph1 PhenoGen
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014722 RatGTEx
SMART SM00233 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I5ZL54 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZU51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A272 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF23 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMM7 ENTREZGENE, UniProtKB/TrEMBL
  A6IPC9 ENTREZGENE, UniProtKB/TrEMBL
  A6IPD1 ENTREZGENE, UniProtKB/TrEMBL
  D4ADX8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Raph1  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1   Raph1_predicted  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Raph1_predicted  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED