Map3k10 (mitogen activated protein kinase kinase kinase 10) - Rat Genome Database

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Gene: Map3k10 (mitogen activated protein kinase kinase kinase 10) Rattus norvegicus
Analyze
Symbol: Map3k10
Name: mitogen activated protein kinase kinase kinase 10
RGD ID: 1308381
Description: Predicted to enable JUN kinase kinase kinase activity; bHLH transcription factor binding activity; and transcription corepressor activity. Involved in positive regulation of apoptotic process. Predicted to be located in cytoplasm. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102552215; LOC308463; mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 10-like; mixed-lineage kinase 2; Mlk2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,083,376 - 92,101,676 (-)NCBIGRCr8
mRatBN7.2182,955,784 - 82,974,084 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,955,207 - 82,974,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,358,366 - 88,376,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,838,960 - 96,857,277 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,114,229 - 90,132,536 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,473,178 - 84,491,689 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,473,071 - 84,491,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,686,287 - 85,704,608 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,750,424 - 82,768,725 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,828,531 - 82,847,698 (-)NCBI
Celera177,361,918 - 77,380,218 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The c-jun kinase/stress-activated pathway: regulation, function and role in human disease. Johnson GL and Nakamura K, Biochim Biophys Acta. 2007 Aug;1773(8):1341-8. Epub 2007 Jan 4.
4. Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells. Kim KY, etal., J Biol Chem 2004 Jul 9;279(28):29478-84. Epub 2004 Apr 6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. Wilhelm M, etal., J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.
11. The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis. Xu Z, etal., Mol Cell Biol. 2001 Jul;21(14):4713-24.
Additional References at PubMed
PMID:10801775   PMID:11152698   PMID:14690535   PMID:15062575   PMID:17584736   PMID:18455992   PMID:19801649  


Genomics

Comparative Map Data
Map3k10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,083,376 - 92,101,676 (-)NCBIGRCr8
mRatBN7.2182,955,784 - 82,974,084 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,955,207 - 82,974,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,358,366 - 88,376,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,838,960 - 96,857,277 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,114,229 - 90,132,536 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,473,178 - 84,491,689 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,473,071 - 84,491,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,686,287 - 85,704,608 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,750,424 - 82,768,725 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,828,531 - 82,847,698 (-)NCBI
Celera177,361,918 - 77,380,218 (-)NCBICelera
Cytogenetic Map1q21NCBI
MAP3K10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,191,426 - 40,215,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,191,426 - 40,215,575 (+)EnsemblGRCh38hg38GRCh38
GRCh371940,697,333 - 40,721,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,389,491 - 45,413,314 (+)NCBINCBI36Build 36hg18NCBI36
Build 341945,389,490 - 45,413,314NCBI
Celera1937,497,195 - 37,521,034 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,132,671 - 37,156,423 (+)NCBIHuRef
CHM1_11940,697,319 - 40,721,159 (+)NCBICHM1_1
T2T-CHM13v2.01943,011,933 - 43,036,086 (+)NCBIT2T-CHM13v2.0
Map3k10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39727,355,800 - 27,374,059 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl727,355,800 - 27,374,023 (-)EnsemblGRCm39 Ensembl
GRCm38727,656,375 - 27,674,630 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,656,375 - 27,674,598 (-)EnsemblGRCm38mm10GRCm38
MGSCv37728,441,396 - 28,459,617 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36727,365,135 - 27,383,358 (-)NCBIMGSCv36mm8
Celera722,238,533 - 22,256,744 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.95NCBI
Map3k10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555781,018,560 - 1,036,901 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555781,018,280 - 1,037,553 (-)NCBIChiLan1.0ChiLan1.0
MAP3K10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,451,004 - 46,475,968 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,321,631 - 48,345,841 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,236,438 - 37,260,314 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11945,753,227 - 45,775,421 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1945,753,354 - 45,775,137 (+)Ensemblpanpan1.1panPan2
MAP3K10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,422,239 - 113,435,979 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,422,518 - 113,428,688 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,823,096 - 112,840,182 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01114,020,015 - 114,037,107 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1114,020,155 - 114,036,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,578,951 - 113,596,038 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01113,211,471 - 113,228,553 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01114,205,343 - 114,222,433 (-)NCBIUU_Cfam_GSD_1.0
Map3k10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,195,287 - 14,210,149 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366612,623,356 - 2,638,218 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP3K10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,527,002 - 48,545,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,526,619 - 48,545,160 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,298,656 - 44,317,044 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAP3K10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1634,639,528 - 34,674,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl634,639,506 - 34,674,337 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607312,743,495 - 12,767,293 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map3k10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925232,986 - 249,794 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624925232,397 - 250,083 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Map3k10
58 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:60
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000034609
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat

Markers in Region
D1Rat336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,968,982 - 82,969,157 (+)MAPPERmRatBN7.2
Rnor_6.0184,486,378 - 84,486,552NCBIRnor6.0
Rnor_5.0185,699,487 - 85,699,661UniSTSRnor5.0
RGSC_v3.4182,763,623 - 82,763,798RGDRGSC3.4
RGSC_v3.4182,763,624 - 82,763,798UniSTSRGSC3.4
RGSC_v3.1182,841,735 - 82,841,909RGD
Celera177,375,118 - 77,375,291UniSTS
RH 3.4 Map1827.7RGD
RH 3.4 Map1827.7UniSTS
SHRSP x BN Map140.11UniSTS
SHRSP x BN Map140.11RGD
FHH x ACI Map142.29RGD
Cytogenetic Map1q21UniSTS
RH138412  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,958,791 - 82,958,923 (+)MAPPERmRatBN7.2
Rnor_6.0184,476,187 - 84,476,318NCBIRnor6.0
Rnor_5.0185,689,296 - 85,689,427UniSTSRnor5.0
RGSC_v3.4182,753,433 - 82,753,564UniSTSRGSC3.4
Celera177,364,927 - 77,365,058UniSTS
RH 3.4 Map1841.5UniSTS
Cytogenetic Map1q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 72 2 29
Low 3 43 57 41 19 41 8 8 2 33 12 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000034609   ⟹   ENSRNOP00000031328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl182,955,207 - 82,974,084 (-)Ensembl
Rnor_6.0 Ensembl184,473,071 - 84,491,466 (-)Ensembl
RefSeq Acc Id: NM_001395098   ⟹   NP_001382027
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,083,376 - 92,101,676 (-)NCBI
mRatBN7.2182,955,784 - 82,974,084 (-)NCBI
RefSeq Acc Id: XM_039111551   ⟹   XP_038967479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,083,376 - 92,096,109 (-)NCBI
mRatBN7.2182,955,784 - 82,968,517 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001382027 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967479 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO91626 (Get FASTA)   NCBI Sequence Viewer  
  D3ZG83 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000031328
  ENSRNOP00000031328.6
  ENSRNOP00055047904
  ENSRNOP00060039443
  ENSRNOP00065047968
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000031328   ⟸   ENSRNOT00000034609
RefSeq Acc Id: XP_038967479   ⟸   XM_039111551
- Peptide Label: isoform X1
- UniProtKB: A6J9E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382027   ⟸   NM_001395098
- UniProtKB: D3ZG83 (UniProtKB/Swiss-Prot)
Protein Domains
Protein kinase   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZG83-F1-model_v2 AlphaFold D3ZG83 1-940 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308381 AgrOrtholog
BioCyc Gene G2FUF-60296 BioCyc
Ensembl Genes ENSRNOG00000023521 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055033586 UniProtKB/Swiss-Prot
  ENSRNOG00060027299 UniProtKB/Swiss-Prot
  ENSRNOG00065033943 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000034609 ENTREZGENE
  ENSRNOT00000034609.7 UniProtKB/Swiss-Prot
  ENSRNOT00055058064 UniProtKB/Swiss-Prot
  ENSRNOT00060047383 UniProtKB/Swiss-Prot
  ENSRNOT00065058291 UniProtKB/Swiss-Prot
Gene3D-CATH SH3 Domains UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  MLK1-3_SH3 UniProtKB/Swiss-Prot
  MLK1-4 UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
NCBI Gene 308463 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE UniProtKB/Swiss-Prot
  SERINE-THREONINE PROTEIN KINASE UniProtKB/Swiss-Prot
Pfam Pkinase_Tyr UniProtKB/Swiss-Prot
  SH3_9 UniProtKB/Swiss-Prot
PhenoGen Map3k10 PhenoGen
PIRSF MAPKKK9_11 UniProtKB/Swiss-Prot
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot
  TYRKINASE UniProtKB/Swiss-Prot
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000023521 RatGTEx
  ENSRNOG00055033586 RatGTEx
  ENSRNOG00060027299 RatGTEx
  ENSRNOG00065033943 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
UniProt A6J9E6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZG83 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Map3k10  mitogen activated protein kinase kinase kinase 10  LOC102552215  mitogen-activated protein kinase kinase kinase 10-like  Data merged from RGD:7556707 737654 PROVISIONAL
2013-12-17 LOC102552215  mitogen-activated protein kinase kinase kinase 10-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Map3k10  mitogen activated protein kinase kinase kinase 10  Map3k10_predicted  mitogen activated protein kinase kinase kinase 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Map3k10_predicted  mitogen activated protein kinase kinase kinase 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED