Ly9 (lymphocyte antigen 9) - Rat Genome Database

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Pathways
Gene: Ly9 (lymphocyte antigen 9) Rattus norvegicus
Analyze
Symbol: Ly9
Name: lymphocyte antigen 9
RGD ID: 1308341
Description: Predicted to be involved in T-helper 17 cell lineage commitment and positive regulation of interleukin-17 production. Predicted to be located in cell surface and plasma membrane. Predicted to be active in external side of plasma membrane. Orthologous to human LY9 (lymphocyte antigen 9); INTERACTS WITH 1-naphthyl isothiocyanate; acetamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289227; T-lymphocyte surface antigen Ly-9
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,610,762 - 86,633,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1386,611,784 - 86,657,293 (-)EnsemblGRCr8
mRatBN7.21384,079,345 - 84,100,783 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,079,458 - 84,100,823 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1386,587,072 - 86,606,550 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,984,908 - 88,004,379 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,184,633 - 85,203,854 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,002,779 - 90,022,346 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,002,783 - 90,022,269 (-)Ensemblrn6Rnor6.0
Rnor_5.01394,624,495 - 94,644,219 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41387,581,203 - 87,600,810 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1383,711,096 - 83,730,526 (-)NCBICelera
RGSC_v3.11387,769,871 - 87,789,694 (-)NCBI
Cytogenetic Map13q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1506686   PMID:22184727  


Genomics

Comparative Map Data
Ly9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,610,762 - 86,633,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1386,611,784 - 86,657,293 (-)EnsemblGRCr8
mRatBN7.21384,079,345 - 84,100,783 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,079,458 - 84,100,823 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1386,587,072 - 86,606,550 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,984,908 - 88,004,379 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,184,633 - 85,203,854 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,002,779 - 90,022,346 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,002,783 - 90,022,269 (-)Ensemblrn6Rnor6.0
Rnor_5.01394,624,495 - 94,644,219 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41387,581,203 - 87,600,810 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1383,711,096 - 83,730,526 (-)NCBICelera
RGSC_v3.11387,769,871 - 87,789,694 (-)NCBI
Cytogenetic Map13q24NCBI
LY9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,796,174 - 160,828,255 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,796,074 - 160,828,483 (+)Ensemblhg38GRCh38
GRCh371160,765,964 - 160,798,045 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,032,552 - 159,064,669 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341157,579,000 - 157,611,116NCBI
Celera1133,834,603 - 133,866,716 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,122,027 - 132,154,181 (+)NCBIHuRef
CHM1_11162,161,240 - 162,193,425 (+)NCBICHM1_1
T2T-CHM13v2.01159,933,205 - 159,965,298 (+)NCBIT2T-CHM13v2.0
Ly9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,416,172 - 171,434,917 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,416,192 - 171,434,978 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381171,588,613 - 171,607,410 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,588,624 - 171,607,410 (-)Ensemblmm10GRCm38
MGSCv371173,518,744 - 173,537,491 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361173,425,307 - 173,443,949 (-)NCBIMGSCv36mm8
Celera1174,446,275 - 174,464,989 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
LY9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,019,244 - 89,054,064 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,759,668 - 88,794,378 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,151,608 - 136,185,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,075,646 - 140,107,790 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,075,646 - 140,107,784 (+)EnsemblpanPan2panpan1.1
LY9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,522,898 - 21,554,652 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,523,637 - 21,554,579 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3821,595,867 - 21,627,680 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03821,640,415 - 21,671,866 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,640,585 - 21,671,783 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,527,340 - 21,559,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,941,122 - 21,972,926 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,351,067 - 22,382,513 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LY9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,701,359 - 89,729,855 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1489,701,806 - 89,728,848 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,518,786 - 97,545,794 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LY9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,140,059 - 3,145,818 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660382,180,473 - 2,209,597 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ly9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11050,759,699 - 50,778,878 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ly9
217 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:120
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000035498
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
G42060  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,099,761 - 84,099,910 (+)MAPPERmRatBN7.2
Rnor_6.01390,021,262 - 90,021,410NCBIRnor6.0
Rnor_5.01394,643,553 - 94,643,701UniSTSRnor5.0
RGSC_v3.41387,599,682 - 87,599,830UniSTSRGSC3.4
Celera1383,729,573 - 83,729,721UniSTS
Cytogenetic Map13q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 52 110 81 80 49 92 49 6 314 175 11 85 66 78 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000035498   ⟹   ENSRNOP00000036230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,615,234 - 86,633,190 (-)Ensembl
mRatBN7.2 Ensembl1384,082,824 - 84,100,823 (-)Ensembl
Rnor_6.0 Ensembl1390,002,783 - 90,022,269 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096361   ⟹   ENSRNOP00000087223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,611,784 - 86,633,190 (-)Ensembl
mRatBN7.2 Ensembl1384,079,458 - 84,100,823 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100394   ⟹   ENSRNOP00000088162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,611,784 - 86,633,164 (-)Ensembl
mRatBN7.2 Ensembl1384,079,458 - 84,100,757 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103580   ⟹   ENSRNOP00000092458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,611,784 - 86,633,190 (-)Ensembl
mRatBN7.2 Ensembl1384,079,458 - 84,100,823 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113721   ⟹   ENSRNOP00000081109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,611,784 - 86,657,293 (-)Ensembl
mRatBN7.2 Ensembl1384,079,458 - 84,100,823 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165565   ⟹   ENSRNOP00000103047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1386,612,692 - 86,633,190 (-)Ensembl
RefSeq Acc Id: NM_001191673   ⟹   NP_001178602
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,611,755 - 86,633,190 (-)NCBI
mRatBN7.21384,079,345 - 84,100,783 (-)NCBI
Rnor_6.01390,002,783 - 90,022,269 (-)NCBI
Rnor_5.01394,624,495 - 94,644,219 (-)NCBI
Celera1383,711,096 - 83,730,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272129   ⟹   XP_063128199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,610,762 - 86,633,314 (-)NCBI
RefSeq Acc Id: NP_001178602   ⟸   NM_001191673
- UniProtKB: A0A8I6GJS8 (UniProtKB/TrEMBL),   A0A8I5ZS62 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036230   ⟸   ENSRNOT00000035498
Ensembl Acc Id: ENSRNOP00000087223   ⟸   ENSRNOT00000096361
Ensembl Acc Id: ENSRNOP00000088162   ⟸   ENSRNOT00000100394
Ensembl Acc Id: ENSRNOP00000081109   ⟸   ENSRNOT00000113721
Ensembl Acc Id: ENSRNOP00000092458   ⟸   ENSRNOT00000103580
RefSeq Acc Id: XP_063128199   ⟸   XM_063272129
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A5H0 (UniProtKB/TrEMBL),   A0A8I5ZS62 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103047   ⟸   ENSRNOT00000165565
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEF7-F1-model_v2 AlphaFold D3ZEF7 1-655 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699012
Promoter ID:EPDNEW_R9537
Type:single initiation site
Name:Ly9_1
Description:lymphocyte antigen 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01390,022,295 - 90,022,355EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308341 AgrOrtholog
BioCyc Gene G2FUF-17356 BioCyc
Ensembl Genes ENSRNOG00000025069 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035498.7 UniProtKB/TrEMBL
  ENSRNOT00000096361 ENTREZGENE
  ENSRNOT00000096361.2 UniProtKB/TrEMBL
  ENSRNOT00000100394.2 UniProtKB/TrEMBL
  ENSRNOT00000103580 ENTREZGENE
  ENSRNOT00000103580.2 UniProtKB/TrEMBL
  ENSRNOT00000113721.2 UniProtKB/TrEMBL
  ENSRNOT00000165565.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD2/SLAM_rcpt UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report rno:289227 UniProtKB/TrEMBL
NCBI Gene 289227 ENTREZGENE
PANTHER SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE UniProtKB/TrEMBL
  T-LYMPHOCYTE SURFACE ANTIGEN LY-9 UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Ly9 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025069 RatGTEx
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZS62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4J1_RAT UniProtKB/TrEMBL
  A0A8I6A5H0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJS8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LC97_RAT UniProtKB/TrEMBL
  D3ZEF7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ly9  lymphocyte antigen 9   Ly9_predicted  lymphocyte antigen 9 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ly9_predicted  lymphocyte antigen 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED