Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Metribolone results in increased expression of UBA6 protein | CTD | PMID:17152098 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | UBA6 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of UBA6 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBA6 mRNA | CTD | PMID:32109520 and PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-methylcholine | affects expression | ISO | UBA6 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of UBA6 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Uba6 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of UBA6 promoter | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Uba6 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of UBA6 mRNA | CTD | PMID:26251327 | 4-phenylbutyric acid | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | 4-phenylbutyric acid results in decreased expression of UBA6 mRNA | CTD | PMID:14583596 | aflatoxin B1 | decreases expression | ISO | Uba6 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of UBA6 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | UBA6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of UBA6 gene | CTD | PMID:27153756 | aristolochic acid A | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of UBA6 mRNA | CTD | PMID:33212167 | arsane | multiple interactions | ISO | UBA6 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UBA6 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | UBA6 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UBA6 mRNA | CTD | PMID:32525701 | benzo[a]pyrene | decreases expression | ISO | Uba6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of UBA6 mRNA | CTD | PMID:19770486 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of UBA6 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UBA6 mRNA | CTD | PMID:33296240 | cadmium atom | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Cadmium results in increased expression of UBA6 mRNA | CTD | PMID:23369406 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of UBA6 promoter | CTD | PMID:22457795 | caffeine | increases phosphorylation | ISO | UBA6 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of UBA6 protein | CTD | PMID:35688186 | chloropicrin | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of UBA6 mRNA | CTD | PMID:28476498 | cisplatin | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of UBA6 mRNA | CTD | PMID:27392435 | copper(II) sulfate | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of UBA6 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of UBA6 mRNA | CTD | PMID:20106945 | diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of UBA6 mRNA | CTD | PMID:29108742 | dicrotophos | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of UBA6 mRNA | CTD | PMID:28302478 | dieldrin | increases response to substance | ISO | UBA6 (Homo sapiens) | 6480464 | UBA6 gene mutant form results in increased susceptibility to Dieldrin | CTD | PMID:32421776 | enzyme inhibitor | multiple interactions | ISO | UBA6 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of UBA6 protein | CTD | PMID:23301498 | folic acid | decreases expression | ISO | Uba6 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of UBA6 mRNA | CTD | PMID:25629700 | ivermectin | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of UBA6 protein | CTD | PMID:32959892 | mercury dichloride | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of UBA6 mRNA | CTD | PMID:27188386 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of UBA6 mRNA | CTD | PMID:30467583 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of UBA6 gene | CTD | PMID:33148267 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of UBA6 mRNA | CTD | PMID:28801915 | nickel atom | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Nickel results in increased expression of UBA6 mRNA | CTD | PMID:25583101 | paracetamol | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of UBA6 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of UBA6 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Uba6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of UBA6 mRNA | CTD | PMID:36331819 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of UBA6 gene | CTD | PMID:33148267 | SB 431542 | multiple interactions | ISO | UBA6 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of UBA6 protein | CTD | PMID:37664457 | sodium arsenate | increases expression | ISO | Uba6 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of UBA6 mRNA | CTD | PMID:21795629 | sodium arsenate | multiple interactions | ISO | UBA6 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UBA6 mRNA | CTD | PMID:32525701 | sodium arsenite | increases expression | ISO | Uba6 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of UBA6 mRNA | CTD | PMID:33145626 | temozolomide | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of UBA6 mRNA | CTD | PMID:31758290 | testosterone | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of UBA6 mRNA | CTD | PMID:33359661 | thapsigargin | increases expression | ISO | Uba6 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of UBA6 protein | CTD | PMID:24648495 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of UBA6 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | decreases expression | ISO | Uba6 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of UBA6 mRNA | CTD | PMID:29264374 | torcetrapib | increases expression | ISO | UBA6 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of UBA6 mRNA | CTD | PMID:23228038 | valproic acid | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UBA6 mRNA | CTD | PMID:23179753 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of UBA6 mRNA | CTD | PMID:23034163 | vorinostat | decreases expression | ISO | UBA6 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of UBA6 mRNA | CTD | PMID:27188386 | |