Adck1 (aarF domain containing kinase 1)

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Gene: Adck1 (aarF domain containing kinase 1) Rattus norvegicus

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Symbol:

Adck1

Name:

aarF domain containing kinase 1

RGD ID:

1308263

Description:

Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in lipid homeostasis; mitochondrion organization; and regulation of mitochondrion organization. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Orthologous to human ADCK1 (aarF domain containing kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

aarF domain-containing protein kinase 1; LOC366698; uncharacterized aarF domain-containing protein kinase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADCK1 (aarF domain containing kinase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Adck1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adck1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADCK1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADCK1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adck1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADCK1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADCK1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adck1 (aarF domain containing kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MVP (major vault protein)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ADCK1 (aarF domain containing kinase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Adck1 (aarF domain containing kinase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adck1 (aarF domain containing kinase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Adck	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	D2023.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MCP2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adck1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	113,005,333 - 113,107,960 (+)	NCBI		GRCr8
mRatBN7.2	6	107,277,170 - 107,377,057 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	107,277,244 - 107,377,055 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	107,447,792 - 107,547,603 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	107,746,614 - 107,846,436 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	107,116,306 - 107,216,119 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	111,640,652 - 111,741,418 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	111,642,411 - 111,740,481 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	120,923,362 - 121,020,830 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	111,872,315 - 111,992,613 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	111,883,788 - 111,995,600 (+)	NCBI
Celera	6	105,091,084 - 105,190,719 (+)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

chromium(6+) (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

folic acid (ISO)

genistein (ISO)

hydrogen peroxide (ISO)

methoxychlor (EXP)

paracetamol (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid homeostasis (IBA)

mitochondrion organization (IBA)

negative regulation of mitochondrial fusion (ISO)

positive regulation of cristae formation (ISO)

Cellular Component

mitochondrial inner membrane (IBA)

mitochondrion (ISO)

Molecular Function

ATP binding (IEA)

protein kinase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18614015	PMID:31125351

Genomics

Comparative Map Data

Adck1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	113,005,333 - 113,107,960 (+)	NCBI		GRCr8
mRatBN7.2	6	107,277,170 - 107,377,057 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	107,277,244 - 107,377,055 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	107,447,792 - 107,547,603 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	107,746,614 - 107,846,436 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	107,116,306 - 107,216,119 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	111,640,652 - 111,741,418 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	111,642,411 - 111,740,481 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	120,923,362 - 121,020,830 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	111,872,315 - 111,992,613 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	111,883,788 - 111,995,600 (+)	NCBI
Celera	6	105,091,084 - 105,190,719 (+)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

ADCK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	77,800,109 - 77,935,014 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	77,800,109 - 77,935,014 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	78,266,452 - 78,401,357 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	77,336,227 - 77,470,047 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	77,336,226 - 77,470,047	NCBI
Celera	14	58,304,590 - 58,438,453 (+)	NCBI		Celera
Cytogenetic Map	14	q24.3	NCBI
HuRef	14	58,432,570 - 58,566,242 (+)	NCBI		HuRef
CHM1_1	14	78,205,866 - 78,339,895 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	72,009,104 - 72,144,049 (+)	NCBI		T2T-CHM13v2.0

Adck1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	88,327,264 - 88,428,496 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	88,327,324 - 88,428,494 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	88,360,494 - 88,461,726 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	88,360,554 - 88,461,724 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	89,599,245 - 89,700,162 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	88,874,056 - 88,975,197 (+)	NCBI		MGSCv36	mm8
Celera	12	89,684,194 - 89,789,768 (+)	NCBI		Celera
Cytogenetic Map	12	D2- D3	NCBI
cM Map	12	42.55	NCBI

Adck1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	1,638,668 - 1,751,962 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	1,638,673 - 1,760,791 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADCK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	78,887,369 - 79,027,201 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	78,103,891 - 78,243,706 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	58,355,670 - 58,495,032 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	77,556,389 - 77,695,344 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	77,556,389 - 77,695,344 (+)	Ensembl	panpan1.1		panPan2

ADCK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	50,512,342 - 50,666,410 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	50,512,261 - 50,656,958 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	50,199,173 - 50,346,730 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	50,746,049 - 50,892,474 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	50,780,215 - 50,927,625 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	50,408,135 - 50,573,880 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	50,431,378 - 50,578,902 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	50,830,024 - 50,977,731 (+)	NCBI		UU_Cfam_GSD_1.0

Adck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	25,369,304 - 25,472,845 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	6,592,405 - 6,698,140 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	6,579,461 - 6,699,664 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADCK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	100,777,144 - 100,902,948 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	100,777,125 - 100,909,140 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	106,832,993 - 106,903,089 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADCK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	55,063,870 - 55,193,475 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	55,080,088 - 55,193,471 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	43,247,543 - 43,375,449 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adck1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	23,976,811 - 24,116,546 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	23,994,929 - 24,116,551 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Adck1
484 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	373
Count of miRNA genes:	215
Interacting mature miRNAs:	257
Transcripts:	ENSRNOT00000016962
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	72202632	115200186	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	73463459	109394713	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	82523650	110548006	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	67262953	112262953	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72202632	117202632	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	71201409	116201409	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
1300076	Glom8	Glomerulus QTL 8	7	9e-09	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat

Markers in Region

D6Rat57

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	107,366,652 - 107,366,874 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	111,730,516 - 111,730,737	NCBI	Rnor6.0
Rnor_5.0	6	121,009,928 - 121,010,149	UniSTS	Rnor5.0
RGSC_v3.4	6	111,983,108 - 111,983,329	UniSTS	RGSC3.4
RGSC_v3.4	6	111,983,107 - 111,983,328	RGD	RGSC3.4
RGSC_v3.1	6	111,986,638 - 111,986,859	RGD
Celera	6	105,181,252 - 105,181,473	UniSTS
RH 3.4 Map	6	744.5	UniSTS
RH 3.4 Map	6	744.5	RGD
RH 2.0 Map	6	992.3	RGD
FHH x ACI Map	6	69.11	RGD
Cytogenetic Map	6	q31	UniSTS

D6Rat81

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	107,351,142 - 107,351,382 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	111,715,478 - 111,715,717	NCBI	Rnor6.0
Rnor_5.0	6	120,994,890 - 120,995,129	UniSTS	Rnor5.0
RGSC_v3.4	6	111,967,597 - 111,967,837	RGD	RGSC3.4
RGSC_v3.4	6	111,967,598 - 111,967,837	UniSTS	RGSC3.4
RGSC_v3.1	6	111,971,129 - 111,971,368	RGD
Celera	6	105,165,742 - 105,165,981	UniSTS
RH 3.4 Map	6	744.5	RGD
RH 3.4 Map	6	744.5	UniSTS
RH 2.0 Map	6	991.2	RGD
SHRSP x BN Map	6	65.7398	RGD
FHH x ACI Map	6	69.11	RGD
Cytogenetic Map	6	q31	UniSTS

D6Rat162

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	6	120,961,921 - 120,962,177	NCBI	Rnor5.0
RGSC_v3.4	6	111,934,251 - 111,934,579	UniSTS	RGSC3.4
RGSC_v3.4	6	111,934,250 - 111,934,579	RGD	RGSC3.4
RGSC_v3.1	6	111,937,779 - 111,938,210	RGD
Celera	6	105,132,401 - 105,132,729	UniSTS
SHRSP x BN Map	6	65.7398	UniSTS
SHRSP x BN Map	6	65.7398	RGD
Cytogenetic Map	6	q31	UniSTS

AI169386

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	107,375,870 - 107,376,028 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	111,740,232 - 111,740,389	NCBI	Rnor6.0
Rnor_5.0	6	121,019,644 - 121,019,801	UniSTS	Rnor5.0
RGSC_v3.4	6	111,992,364 - 111,992,521	UniSTS	RGSC3.4
Celera	6	105,190,470 - 105,190,627	UniSTS
RH 3.4 Map	6	755.6	UniSTS
Cytogenetic Map	6	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016962 ⟹ ENSRNOP00000016962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	107,277,458 - 107,376,120 (+)	Ensembl
Rnor_6.0 Ensembl	6	111,642,411 - 111,740,481 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104832 ⟹ ENSRNOP00000078150

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	107,277,244 - 107,377,055 (+)	Ensembl

RefSeq Acc Id:

NM_001108985 ⟹ NP_001102455

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,386 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,474 - 107,377,057 (+)	NCBI
Rnor_6.0	6	111,642,411 - 111,740,481 (+)	NCBI
Rnor_5.0	6	120,923,362 - 121,020,830 (+)	NCBI
RGSC_v3.4	6	111,872,315 - 111,992,613 (+)	RGD
Celera	6	105,091,084 - 105,190,719 (+)	RGD

Sequence:

show sequence

GCCCCCTCCGCTGTGACTCTTCGCTCGGTGCCCTAGCGGTCGTTAGTGTGGACTGGCCACTTGG
GTGGCCCAACCTTGCGTGCCCCGGAGTAGGGTCTACGAGTGGCTCCGCCAGAAGCCTTCATACA
TCGGTGGCCTTGTGGGCTCCCACGCAGAGGGTCTGGGGACATGGCCAGAAAGGCTATCAAGCTT
GCTTCGTGGACCAGCATGGCTCTTGCTGCCTCCGGGGTCTACCTCTACAGCAACAGCTACTTGG
ACCCTAGTGACTTTGGCGCTGTCAGGGTGGGCAGAGCTGTTGCTACGACAGCTGTCATCAGCTA
TGACTACCTCACCTCCCTGAGGAGTGTCCCATATGGCTCAGAGGAGTATTTGCAGCGTCGATCC
CAGATCCATGATTTGTTCCTGAGCTTCGATGACACCCCTCTCGGGGCAGCCTCCCTGGCCCAGG
TCCACAAGGCAGTATTGCATGATGGCCGGACAGTGGCAGTGAAAGTCCAGCACCCAAAAGTTCA
GGCTCAAAGCTCCAAGGACATTCTCCTGATGGAGGTGCTTGTCCTGGCTGTGAAGCAACTTTTC
CCAGATTTTGAATTCATGTGGCTGGTGGATGAAGCCAAGAAGAACCTGCCTCTCGAGTTGGACT
TCCTAAACGAAGGGAGGAACGCTGAGAAAGTGGCCCACATGCTCAAGCACTTTGACTTCCTAAA
GGTCCCCCAGATCCACTGGGAGCTGTCTACCAAGAGGGTGCTCCTGATGGAATTTGTGGAGGGA
GGTCAGGTCAACGACAGGGCCTACATGGAGAAGAACCGGATCGATGTGAATGAGATCTCCTGCC
ACCTAGGCAAGATGTACAGTGAGATGATCTTTGTCAATGGCTTCGTACACTGTGACCCCCACCC
AGGCAATGTGCTGGTGCGGAAGCGTCCTGACACGGGCAAGGCTGAGATTGTCCTCTTGGATCAT
GGGCTCTACCAGGTGCTCACGGAGGAGTTCCGCCTGGACTACTGCAATCTATGGCAGTCTCTGA
TCTGGACCGACTTGGACAGAGTGAAATATTACAGCCAGCGCCTGGGGGCTGCAGACCTCTACCC
ACTGTTTGCCTGTATGCTGACCGCCCGGTCTTGGGCCTCAGTCAAACAGGGCATTGGGCAAGCT
CCAGTCTCTGCTACTGAGGACTCAGAGATTCGCAATAATGCAGCCTGCTACCTGCCTGAGATCA
GCCAGCTCCTTAACCATGTGCCTCGCCAGATGCTGCTCATCCTGAAGACCAACGATCTACTCCG
CAGCATCGAGACCACCCTGGGCACGCGGTCCAGCGCCAGTTCCTTCCTCAACATGTCTCGGTGT
TGTATCCGGGCGCTGGCTGAGCATCGGAAGAGGGATGCCGGCTCATTCTTCAGAAGGACCCAGA
TATCTTTCAGTGAGGCCTTCAGCCTGTGGCAGATTAGCCTTCATGAACTTCTGCTTCGAGTGAA
GGCCTTGAGGCTAGCTTGTTGGGTCTCAGCTCTCCTGGGCTGGCTGACTCGGGCTCCATACTGA
ATGTGACTGTCTTTCCCTGCCCCTTCCTAGTGTCTTTCCACACCTCATTTTTTCCTTCATGCTG
GGACTACCCACTGACCCATCCATGTCTGTCTAGGGTTGGCCTGTGGTCCCAGGGTGGACGTCCA
TGGCACCATCAGCCTCTGCCATTGGAGCCCTTGCCTCGTGGTGGCCTTGTCTGGGGGTCCTGGA
ATGACCTGGAGAGTGGTTTTCTTTCCTCCAGGGAGGGGATAAAACTACCTACCTCCCATCTCCT
GTATGTGCCATTGACTTGGTCATCCCTACTTTTATGAGGATTGTCAGAATGGACCAACCACATG
TGTCACAGGGTATGTTTAACCTGTATGGAGTAAGTAGAGTCTTAGAACTTGCTGAGAAGAGACT
GTAGTTTTGATGTATCACTCCCAAAGGGGCACTACCTCAGCGAGGCAGGCTGCATCAGAGAGTG
AATGATGCAGCTGTGGGCTCATGTTGTCATGGTGACACCTTCAGTGTTGTATTTATTGTATGTA
TTGTTTATTGTAATAAACCCTTTCAAGGTTGC

hide sequence

RefSeq Acc Id:

NM_001399747 ⟹ NP_001386676

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,134 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,222 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

NM_001399748 ⟹ NP_001386677

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,111 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,199 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

NM_001399749 ⟹ NP_001386678

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,111 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,199 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

NM_001399750 ⟹ NP_001386679

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,111 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,199 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_039112651 ⟹ XP_038968579

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,346 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,456 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_039112653 ⟹ XP_038968581

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,045,113 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,314,136 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_039112655 ⟹ XP_038968583

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,019,825 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,293,292 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_039112657 ⟹ XP_038968585

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,008,383 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,463 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_039112658 ⟹ XP_038968586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,005,333 - 113,107,960 (+)	NCBI
mRatBN7.2	6	107,277,259 - 107,377,057 (+)	NCBI

RefSeq Acc Id:

XM_063262230 ⟹ XP_063118300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,019,825 - 113,107,960 (+)	NCBI

RefSeq Acc Id:

XM_063262231 ⟹ XP_063118301

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	113,050,626 - 113,107,960 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102455	(Get FASTA)	NCBI Sequence Viewer
	NP_001386676	(Get FASTA)	NCBI Sequence Viewer
	NP_001386677	(Get FASTA)	NCBI Sequence Viewer
	NP_001386678	(Get FASTA)	NCBI Sequence Viewer
	NP_001386679	(Get FASTA)	NCBI Sequence Viewer
	XP_038968579	(Get FASTA)	NCBI Sequence Viewer
	XP_038968581	(Get FASTA)	NCBI Sequence Viewer
	XP_038968583	(Get FASTA)	NCBI Sequence Viewer
	XP_038968585	(Get FASTA)	NCBI Sequence Viewer
	XP_038968586	(Get FASTA)	NCBI Sequence Viewer
	XP_063118300	(Get FASTA)	NCBI Sequence Viewer
	XP_063118301	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL81658	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016962.4
	ENSRNOP00000078150.1

RefSeq Acc Id:	NP_001102455 ⟸ NM_001108985
- Peptide Label:	isoform 2
- UniProtKB:	D3ZRJ0 (UniProtKB/TrEMBL), A6JEB5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARKAIKLASWTSMALAASGVYLYSNSYLDPSDFGAVRVGRAVATTAVISYDYLTSLRSVPYGS EEYLQRRSQIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVL VLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLKHFDFLKVPQIHWELSTKRV LLMEFVEGGQVNDRAYMEKNRIDVNEISCHLGKMYSEMIFVNGFVHCDPHPGNVLVRKRPDTGK AEIVLLDHGLYQVLTEEFRLDYCNLWQSLIWTDLDRVKYYSQRLGAADLYPLFACMLTARSWAS VKQGIGQAPVSATEDSEIRNNAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLGTRSSAS SFLNMSRCCIRALAEHRKRDAGSFFRRTQISFSEAFSLWQISLHELLLRVKALRLACWVSALLG WLTRAPY hide sequence

Ensembl Acc Id:

ENSRNOP00000016962 ⟸ ENSRNOT00000016962

RefSeq Acc Id:	XP_038968586 ⟸ XM_039112658
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038968579 ⟸ XM_039112651
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y874 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968585 ⟸ XM_039112657
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038968583 ⟸ XM_039112655
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038968581 ⟸ XM_039112653
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000078150 ⟸ ENSRNOT00000104832

RefSeq Acc Id:	NP_001386677 ⟸ NM_001399748
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5Y874 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386678 ⟸ NM_001399749
- Peptide Label:	isoform 3

RefSeq Acc Id:	NP_001386679 ⟸ NM_001399750
- Peptide Label:	isoform 3

RefSeq Acc Id:	NP_001386676 ⟸ NM_001399747
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5Y874 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118300 ⟸ XM_063262230
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063118301 ⟸ XM_063262231
- Peptide Label:	isoform X4

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZRJ0-F1-model_v2	AlphaFold	D3ZRJ0	1-455	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694763

Promoter ID:

EPDNEW_R5287

Type:

single initiation site

Name:

Adck1_1

Description:

aarF domain containing kinase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	111,642,455 - 111,642,515	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308263	AgrOrtholog
BioCyc Gene	G2FUF-36688	BioCyc
Ensembl Genes	ENSRNOG00000012685	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000016962.6	UniProtKB/TrEMBL
	ENSRNOT00000104832.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	ABC_1	UniProtKB/TrEMBL
	ADCK1_dom	UniProtKB/TrEMBL
	Kinase-like_dom	UniProtKB/TrEMBL
	Mito_struct-func_regulator	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
KEGG Report	rno:366698	UniProtKB/TrEMBL
NCBI Gene	366698	ENTREZGENE
PANTHER	AARF DOMAIN-CONTAINING PROTEIN KINASE 1	UniProtKB/TrEMBL
	ABC1 FAMILY PROTEIN	UniProtKB/TrEMBL
Pfam	ABC1	UniProtKB/TrEMBL
PhenoGen	Adck1	PhenoGen
PROSITE	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000012685	RatGTEx
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A0A8I5Y874	ENTREZGENE, UniProtKB/TrEMBL
	A6JEB5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZRJ0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Adck1	aarF domain containing kinase 1	Adck1_predicted	aarF domain containing kinase 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Adck1_predicted	aarF domain containing kinase 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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