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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kctd6 | Rat | 1,2-dichloroethane | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of KCTD6 mRNA | CTD | PMID:28960355 | Kctd6 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of KCTD6 mRNA | CTD | PMID:22206623 | Kctd6 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Kctd6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KCTD6 mRNA | CTD | PMID:22206623 | Kctd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KCTD6 mRNA | CTD | PMID:19770486 | Kctd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KCTD6 mRNA | CTD | PMID:33387578 | Kctd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of KCTD6 mRNA | CTD | PMID:22298810 | Kctd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KCTD6 mRNA | CTD | PMID:21215274 | Kctd6 | Rat | 2-methylcholine | affects expression | ISO | KCTD6 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of KCTD6 mRNA | CTD | PMID:21179406 | Kctd6 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Kctd6 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of KCTD6 exon | CTD | PMID:33297965 | Kctd6 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of KCTD6 mRNA | CTD | PMID:30047161 | Kctd6 | Rat | all-trans-retinoic acid | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of KCTD6 mRNA | CTD | PMID:33167477 | Kctd6 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of KCTD6 mRNA | CTD | PMID:38685447 | Kctd6 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of KCTD6 mRNA | CTD | PMID:30047161 | Kctd6 | Rat | arsane | affects methylation | ISO | KCTD6 (Homo sapiens) | 6480464 | Arsenic affects the methylation of KCTD6 gene | CTD | PMID:25304211 | Kctd6 | Rat | arsenic atom | affects methylation | ISO | KCTD6 (Homo sapiens) | 6480464 | Arsenic affects the methylation of KCTD6 gene | CTD | PMID:25304211 | Kctd6 | Rat | arsenite(3-) | multiple interactions | ISO | KCTD6 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to KCTD6 mRNA] | CTD | PMID:32406909 | Kctd6 | Rat | arsenous acid | increases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KCTD6 mRNA | CTD | PMID:20458559 | Kctd6 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of KCTD6 gene | CTD | PMID:28931070 | Kctd6 | Rat | benzo[a]pyrene | increases expression | ISO | Kctd6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of KCTD6 mRNA | CTD | PMID:22228805 | Kctd6 | Rat | benzo[a]pyrene | affects methylation | ISO | KCTD6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KCTD6 5' UTR | CTD | PMID:27901495 | Kctd6 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KCTD6 mRNA | CTD | PMID:25181051 | Kctd6 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KCTD6 mRNA | CTD | PMID:34973380 | Kctd6 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of KCTD6 gene | CTD | PMID:28505145 | Kctd6 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of KCTD6 mRNA | CTD | PMID:33453195 | Kctd6 | Rat | cadmium dichloride | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of KCTD6 mRNA | CTD | PMID:38568856 | Kctd6 | Rat | CGP 52608 | multiple interactions | ISO | KCTD6 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KCTD6 gene] | CTD | PMID:28238834 | Kctd6 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KCTD6 mRNA | CTD | PMID:17602206 | Kctd6 | Rat | copper(II) sulfate | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of KCTD6 mRNA | CTD | PMID:19549813 | Kctd6 | Rat | diarsenic trioxide | increases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KCTD6 mRNA | CTD | PMID:20458559 | Kctd6 | Rat | Dibutyl phosphate | affects expression | ISO | KCTD6 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of KCTD6 mRNA | CTD | PMID:37042841 | Kctd6 | Rat | dicrotophos | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of KCTD6 mRNA | CTD | PMID:28302478 | Kctd6 | Rat | doxorubicin | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of KCTD6 mRNA | CTD | PMID:29803840 | Kctd6 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of KCTD6 mRNA | CTD | PMID:29391264 | Kctd6 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of KCTD6 mRNA | CTD | PMID:23962444 | Kctd6 | Rat | folic acid | multiple interactions | ISO | Kctd6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KCTD6 mRNA | CTD | PMID:22206623 | Kctd6 | Rat | folic acid | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of KCTD6 mRNA | CTD | PMID:25629700 | Kctd6 | Rat | formaldehyde | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of KCTD6 mRNA | CTD | PMID:20655997 | Kctd6 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of KCTD6 mRNA | CTD | PMID:33387578 | Kctd6 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of KCTD6 mRNA | CTD | PMID:24136188 | Kctd6 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of KCTD6 mRNA | CTD | PMID:30047161 | Kctd6 | Rat | methylmercury chloride | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of KCTD6 mRNA | CTD | PMID:28001369 | Kctd6 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of KCTD6 gene | CTD | PMID:33148267 | Kctd6 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KCTD6 mRNA more ... | CTD | PMID:17602206 and PMID:25374375 | Kctd6 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of KCTD6 mRNA | CTD | PMID:33387578 | Kctd6 | Rat | parathion | increases expression | ISO | Kctd6 (Mus musculus) | 6480464 | Parathion results in increased expression of KCTD6 mRNA | CTD | PMID:34813904 | Kctd6 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of KCTD6 mRNA | CTD | PMID:37995155 | Kctd6 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of KCTD6 gene | CTD | PMID:33148267 | Kctd6 | Rat | phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KCTD6 mRNA and [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of KCTD6 promoter | CTD | PMID:25374375 | Kctd6 | Rat | pirinixic acid | increases expression | ISO | Kctd6 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of KCTD6 mRNA | CTD | PMID:16985257 | Kctd6 | Rat | quercetin | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of KCTD6 mRNA | CTD | PMID:21632981 | Kctd6 | Rat | sodium arsenite | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of KCTD6 mRNA | CTD | PMID:38568856 | Kctd6 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of KCTD6 mRNA | CTD | PMID:30047161 | Kctd6 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of KCTD6 mRNA | CTD | PMID:30690589 | Kctd6 | Rat | tetrachloromethane | increases methylation | EXP | | 6480464 | Carbon Tetrachloride results in increased methylation of KCTD6 promoter | CTD | PMID:30690589 | Kctd6 | Rat | troglitazone | decreases expression | ISO | Kctd6 (Mus musculus) | 6480464 | troglitazone results in decreased expression of KCTD6 mRNA | CTD | PMID:28973697 | Kctd6 | Rat | urethane | increases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Urethane results in increased expression of KCTD6 mRNA | CTD | PMID:28818685 | Kctd6 | Rat | valproic acid | affects expression | ISO | Kctd6 (Mus musculus) | 6480464 | Valproic Acid affects the expression of KCTD6 mRNA | CTD | PMID:17963808 | Kctd6 | Rat | valproic acid | increases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KCTD6 mRNA | CTD | PMID:29154799 | Kctd6 | Rat | vanadyl sulfate | decreases expression | ISO | KCTD6 (Homo sapiens) | 6480464 | vanadyl sulfate results in decreased expression of KCTD6 mRNA | CTD | PMID:16330358 | |