Fign (fidgetin, microtubule severing factor) - Rat Genome Database

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Gene: Fign (fidgetin, microtubule severing factor) Rattus norvegicus
Analyze
Symbol: Fign
Name: fidgetin, microtubule severing factor
RGD ID: 1308174
Description: Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in microtubule severing. Predicted to act upstream of or within locomotory behavior. Predicted to be located in nuclear matrix. Predicted to be active in cytoplasm and nucleus. Orthologous to human FIGN (fidgetin, microtubule severing factor); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: fidgetin; LOC295649
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8369,045,918 - 69,169,148 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl369,045,050 - 69,169,988 (-)EnsemblGRCr8
mRatBN7.2348,637,510 - 48,760,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl348,642,496 - 48,760,787 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx351,971,883 - 52,089,709 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0360,555,393 - 60,673,211 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0358,345,891 - 58,463,522 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0349,992,250 - 50,120,601 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl349,992,397 - 50,120,392 (-)Ensemblrn6Rnor6.0
Rnor_5.0356,637,401 - 56,764,164 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4346,006,895 - 46,130,212 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera348,260,684 - 48,378,383 (-)NCBICelera
RGSC_v3.1345,903,265 - 46,026,612 (-)NCBI
Cytogenetic Map3q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
genistein  (EXP)
melphalan  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
pentanal  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA)
cytoplasm  (IBA)
microtubule  (IEA)
nuclear matrix  (IEA,ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16751186   PMID:36586551  


Genomics

Comparative Map Data
Fign
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8369,045,918 - 69,169,148 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl369,045,050 - 69,169,988 (-)EnsemblGRCr8
mRatBN7.2348,637,510 - 48,760,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl348,642,496 - 48,760,787 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx351,971,883 - 52,089,709 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0360,555,393 - 60,673,211 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0358,345,891 - 58,463,522 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0349,992,250 - 50,120,601 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl349,992,397 - 50,120,392 (-)Ensemblrn6Rnor6.0
Rnor_5.0356,637,401 - 56,764,164 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4346,006,895 - 46,130,212 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera348,260,684 - 48,378,383 (-)NCBICelera
RGSC_v3.1345,903,265 - 46,026,612 (-)NCBI
Cytogenetic Map3q21NCBI
FIGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382163,602,611 - 163,736,008 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2163,593,396 - 163,736,012 (-)Ensemblhg38GRCh38
GRCh372164,459,121 - 164,592,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362164,172,364 - 164,300,759 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342164,291,556 - 164,293,651NCBI
Celera2158,074,075 - 158,202,502 (-)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2156,346,627 - 156,474,914 (-)NCBIHuRef
CHM1_12164,470,008 - 164,598,433 (-)NCBICHM1_1
T2T-CHM13v2.02164,059,859 - 164,193,293 (-)NCBIT2T-CHM13v2.0
Fign
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39263,801,852 - 63,928,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl263,801,851 - 63,928,382 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38263,971,508 - 64,098,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl263,971,507 - 64,098,038 (-)Ensemblmm10GRCm38
MGSCv37263,815,418 - 63,936,064 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36263,778,670 - 63,898,827 (-)NCBIMGSCv36mm8
Celera265,662,900 - 65,783,578 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map237.19NCBI
Fign
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544910,271,014 - 10,393,859 (+)Ensembl
ChiLan1.0NW_00495544910,271,125 - 10,400,631 (+)NCBIChiLan1.0ChiLan1.0
FIGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21366,279,486 - 66,407,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B66,289,122 - 66,600,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B168,259,440 - 168,387,036 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B168,258,315 - 168,385,768 (-)EnsemblpanPan2panpan1.1
FIGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,914,023 - 9,045,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl368,920,224 - 8,922,977 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha369,049,767 - 9,190,855 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0369,038,947 - 9,180,410 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl369,039,164 - 9,180,469 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,048,565 - 9,189,817 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,106,216 - 9,231,397 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0369,220,027 - 9,345,231 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fign
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303126,059,464 - 126,183,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646915,434,127 - 15,553,438 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493646915,434,150 - 15,556,167 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1570,262,091 - 70,394,095 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11570,255,270 - 70,394,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21578,089,130 - 78,245,808 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11049,035,120 - 49,453,559 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1049,052,032 - 49,178,962 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040150,341,369 - 150,475,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fign
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247321,770,852 - 1,899,842 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247321,770,794 - 1,904,398 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fign
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1541,517,899 - 41,639,322 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fign
1093 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:61
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000006175
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)35986366373704481Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)34790417270710963Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)34790417270710963Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)35860129171157804Rat
10450813Scl74Serum cholesterol level QTL 745.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)35860129171157804Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)34790417270710963Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)34790417270710963Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)34790417270710963Rat
10450852Stl33Serum triglyceride level QTL 333.40.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)35860129171157804Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
4889975Bmd81Bone mineral density QTL 814.3tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)35911940270710963Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
AU022255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2348,686,905 - 48,687,125 (+)MAPPERmRatBN7.2
Rnor_6.0350,037,242 - 50,037,461NCBIRnor6.0
Rnor_5.0356,680,974 - 56,681,193UniSTSRnor5.0
RGSC_v3.4346,050,510 - 46,050,729UniSTSRGSC3.4
Celera348,304,760 - 48,304,979UniSTS
Cytogenetic Map3q21UniSTS
FIGN__6723  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2348,643,620 - 48,644,215 (+)MAPPERmRatBN7.2
Rnor_6.0349,993,126 - 49,993,720NCBIRnor6.0
Rnor_5.0356,637,905 - 56,638,499UniSTSRnor5.0
RGSC_v3.4346,007,561 - 46,008,155UniSTSRGSC3.4
Celera348,261,421 - 48,262,015UniSTS
Cytogenetic Map3q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 12 67 150 91 90 59 27 59 6 284 127 11 129 79 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000006175   ⟹   ENSRNOP00000006175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,050,817 - 69,055,430 (-)Ensembl
mRatBN7.2 Ensembl348,642,892 - 48,760,705 (-)Ensembl
Rnor_6.0 Ensembl349,992,397 - 50,120,392 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107158   ⟹   ENSRNOP00000081312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,050,817 - 69,055,430 (-)Ensembl
mRatBN7.2 Ensembl348,642,496 - 48,760,787 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124351   ⟹   ENSRNOP00000112450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,047,402 - 69,120,372 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129006   ⟹   ENSRNOP00000099831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,050,086 - 69,168,136 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000146492   ⟹   ENSRNOP00000099650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,045,691 - 69,169,988 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148803   ⟹   ENSRNOP00000102384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,045,050 - 69,169,330 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000154545   ⟹   ENSRNOP00000102300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,047,404 - 69,120,372 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000164879   ⟹   ENSRNOP00000104156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,047,402 - 69,120,372 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000166797   ⟹   ENSRNOP00000102928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,045,097 - 69,169,988 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000168413   ⟹   ENSRNOP00000104149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl369,045,097 - 69,169,988 (-)Ensembl
RefSeq Acc Id: NM_001106484   ⟹   NP_001099954
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8369,051,292 - 69,169,108 (-)NCBI
mRatBN7.2348,642,884 - 48,760,705 (-)NCBI
Rnor_6.0349,992,393 - 50,120,392 (-)NCBI
Rnor_5.0356,637,401 - 56,764,164 (-)NCBI
RGSC_v3.4346,006,895 - 46,130,212 (-)RGD
Celera348,260,684 - 48,378,383 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761888   ⟹   XP_008760110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8369,045,918 - 69,168,933 (-)NCBI
mRatBN7.2348,637,510 - 48,760,772 (-)NCBI
Rnor_6.0349,992,250 - 50,120,601 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761889   ⟹   XP_008760111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8369,045,918 - 69,168,933 (-)NCBI
mRatBN7.2348,637,510 - 48,713,087 (-)NCBI
Rnor_6.0349,992,250 - 50,049,778 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761890   ⟹   XP_008760112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8369,045,918 - 69,169,148 (-)NCBI
mRatBN7.2348,637,510 - 48,760,771 (-)NCBI
Rnor_6.0349,992,250 - 50,120,601 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063283273   ⟹   XP_063139343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8369,045,918 - 69,168,933 (-)NCBI
RefSeq Acc Id: NP_001099954   ⟸   NM_001106484
- UniProtKB: D3ZYS4 (UniProtKB/TrEMBL),   A6HLW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760112   ⟸   XM_008761890
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZRP0 (UniProtKB/TrEMBL),   A6HLW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760110   ⟸   XM_008761888
- Peptide Label: isoform X1
- UniProtKB: D3ZYS4 (UniProtKB/TrEMBL),   A6HLW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760111   ⟸   XM_008761889
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZRP0 (UniProtKB/TrEMBL),   A6HLW5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006175   ⟸   ENSRNOT00000006175
Ensembl Acc Id: ENSRNOP00000081312   ⟸   ENSRNOT00000107158
RefSeq Acc Id: XP_063139343   ⟸   XM_063283273
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZRP0 (UniProtKB/TrEMBL),   A6HLW5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104149   ⟸   ENSRNOT00000168413
Ensembl Acc Id: ENSRNOP00000099650   ⟸   ENSRNOT00000146492
Ensembl Acc Id: ENSRNOP00000102384   ⟸   ENSRNOT00000148803
Ensembl Acc Id: ENSRNOP00000102928   ⟸   ENSRNOT00000166797
Ensembl Acc Id: ENSRNOP00000102300   ⟸   ENSRNOT00000154545
Ensembl Acc Id: ENSRNOP00000104156   ⟸   ENSRNOT00000164879
Ensembl Acc Id: ENSRNOP00000099831   ⟸   ENSRNOT00000129006
Ensembl Acc Id: ENSRNOP00000112450   ⟸   ENSRNOT00000124351
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYS4-F1-model_v2 AlphaFold D3ZYS4 1-759 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308174 AgrOrtholog
BioCyc Gene G2FUF-49572 BioCyc
Ensembl Genes ENSRNOG00000004679 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006175.8 UniProtKB/TrEMBL
  ENSRNOT00000107158.2 UniProtKB/TrEMBL
  ENSRNOT00000124351.1 UniProtKB/TrEMBL
  ENSRNOT00000129006 ENTREZGENE
  ENSRNOT00000129006.1 UniProtKB/TrEMBL
  ENSRNOT00000146492.1 UniProtKB/TrEMBL
  ENSRNOT00000148803.1 UniProtKB/TrEMBL
  ENSRNOT00000154545.1 UniProtKB/TrEMBL
  ENSRNOT00000164879.1 UniProtKB/TrEMBL
  ENSRNOT00000166797 ENTREZGENE
  ENSRNOT00000166797.1 UniProtKB/TrEMBL
  ENSRNOT00000168413.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  Fidgetin_ATPase UniProtKB/TrEMBL
  MT-severing_AAA_ATPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
KEGG Report rno:295649 UniProtKB/TrEMBL
NCBI Gene 295649 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/TrEMBL
  FIDGETIN UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
PhenoGen Fign PhenoGen
PROSITE AAA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004679 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZRP0 ENTREZGENE
  A6HLW4 ENTREZGENE, UniProtKB/TrEMBL
  A6HLW5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYS4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8I5ZRP0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Fign  fidgetin, microtubule severing factor  Fign  fidgetin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fign  fidgetin   Fign_predicted  fidgetin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fign_predicted  fidgetin (predicted)      Symbol and Name status set to approved 70820 APPROVED