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Gene: Arih1 (ariadne RBR E3 ubiquitin protein ligase 1) Rattus norvegicus

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Symbol:

Arih1

Name:

ariadne RBR E3 ubiquitin protein ligase 1

RGD ID:

1308131

Description:

Predicted to enable enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in Lewy body and nuclear body. Predicted to be part of cullin-RING ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1; ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila); ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1; ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila); E3 ubiquitin-protein ligase ARIH1; LOC300756

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CUEDC2 (CUE domain containing 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	arih1l (ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	arih1l (ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	arih1 (ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12362	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG12362	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	HEL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HEL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ari-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ari-1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ari-1.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ari-1.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ari-1.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C17H11.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	arih1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	68,673,199 - 68,775,648 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	68,673,200 - 68,775,572 (-)	Ensembl				GRCr8
mRatBN7.2	8	59,777,378 - 59,879,762 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	59,777,379 - 59,880,245 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	65,301,933 - 65,403,940 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	63,574,949 - 63,676,955 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	61,444,284 - 61,546,293 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	64,166,359 - 64,268,555 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	64,166,360 - 64,268,555 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	63,928,309 - 64,030,505 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	63,201,871 - 63,305,302 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	59,219,248 - 59,321,584 (-)	NCBI		Celera
RGSC_v3.1	8	63,223,929 - 63,324,356 (-)	NCBI
Cytogenetic Map	8	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aortic aneurysm (ISO)

Marfan syndrome (ISO)

thoracic aortic aneurysm (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calciol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

dimethyl sulfoxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

etoposide (ISO)

fenofibrate (ISO)

fenvalerate (EXP)

flutamide (EXP)

FR900359 (ISO)

GSK-J4 (ISO)

hypochlorous acid (ISO)

ivermectin (ISO)

ketamine (EXP)

methamphetamine (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

Methylazoxymethanol acetate (EXP)

methylmercury chloride (ISO)

mitomycin C (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

ouabain (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rotenone (EXP)

SB 431542 (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

temozolomide (ISO)

tetrachloromethane (ISO)

tetrahydropalmatine (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trimellitic anhydride (ISO)

valproic acid (ISO)

vitamin E (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (IEA,ISO)

ubiquitin-dependent protein catabolic process (IBA,ISO)

Cellular Component

Cul2-RING ubiquitin ligase complex (ISO)

Cul3-RING ubiquitin ligase complex (ISO)

Cul4A-RING E3 ubiquitin ligase complex (ISO)

cytoplasm (IBA,ISO)

Lewy body (ISO)

nuclear body (ISO)

nucleoplasm (ISO)

nucleus (IBA)

SCF ubiquitin ligase complex (ISO)

ubiquitin ligase complex (IBA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

transferase activity (IEA)

ubiquitin conjugating enzyme binding (IBA,ISO)

ubiquitin protein ligase activity (IBA,IEA)

ubiquitin protein ligase binding (ISO)

ubiquitin-protein transferase activity (IEA,ISO)

zinc ion binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:8889548	PMID:10431818	PMID:11278816	PMID:14623119	PMID:15236971	PMID:21532592	PMID:21590270	PMID:23059369	PMID:23707686	PMID:24076655	PMID:27565346	PMID:28131823

Genomics

Comparative Map Data

Arih1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	68,673,199 - 68,775,648 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	68,673,200 - 68,775,572 (-)	Ensembl				GRCr8
mRatBN7.2	8	59,777,378 - 59,879,762 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	59,777,379 - 59,880,245 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	65,301,933 - 65,403,940 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	63,574,949 - 63,676,955 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	61,444,284 - 61,546,293 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	64,166,359 - 64,268,555 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	64,166,360 - 64,268,555 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	63,928,309 - 64,030,505 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	63,201,871 - 63,305,302 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	59,219,248 - 59,321,584 (-)	NCBI		Celera
RGSC_v3.1	8	63,223,929 - 63,324,356 (-)	NCBI
Cytogenetic Map	8	q24	NCBI

ARIH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	72,474,330 - 72,602,987 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	72,474,308 - 72,602,987 (+)	Ensembl			hg38	GRCh38
GRCh37	15	72,766,671 - 72,895,328 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	70,553,721 - 70,662,877 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	70,553,720 - 70,662,877	NCBI
Celera	15	49,652,768 - 49,763,614 (+)	NCBI		Celera
Cytogenetic Map	15	q24.1	NCBI
HuRef	15	49,597,019 - 49,709,554 (+)	NCBI		HuRef
CHM1_1	15	72,884,658 - 72,996,840 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	70,291,593 - 70,420,271 (+)	NCBI		T2T-CHM13v2.0

Arih1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	59,295,837 - 59,395,469 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	59,295,541 - 59,393,901 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	59,388,554 - 59,488,186 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	59,388,258 - 59,486,618 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	59,236,361 - 59,334,181 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	59,190,602 - 59,284,291 (-)	NCBI		MGSCv36	mm8
Celera	9	56,615,709 - 56,713,470 (-)	NCBI		Celera
Cytogenetic Map	9	B	NCBI
cM Map	9	32.01	NCBI

Arih1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	4,683,118 - 4,737,994 (-)	Ensembl
ChiLan1.0	NW_004955450	4,683,118 - 4,737,793 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARIH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	61,736,831 - 61,847,988 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	65,901,074 - 66,012,216 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	51,423,132 - 51,534,278 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1 Ensembl	15	70,187,722 - 70,297,226 (+)	Ensembl			panPan2	panpan1.1

ARIH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	35,927,277 - 36,040,168 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	35,927,233 - 36,108,381 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	35,863,589 - 35,988,001 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	36,133,344 - 36,257,840 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	36,133,366 - 36,246,243 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	36,084,559 - 36,202,242 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	36,112,246 - 36,236,422 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	36,367,971 - 36,492,251 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Arih1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	113,974,529 - 114,102,322 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	31,822,592 - 31,947,624 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	31,822,592 - 31,947,624 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARIH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	60,710,051 - 60,824,101 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	60,707,483 - 60,824,117 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	65,167,891 - 65,209,110 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARIH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	10,890,440 - 11,002,812 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	10,893,735 - 11,002,159 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	130,582,412 - 130,699,103 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arih1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624781	1,567,343 - 1,665,766 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Arih1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	53,221,123 - 53,321,098 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Arih1
464 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	507
Count of miRNA genes:	251
Interacting mature miRNAs:	329
Transcripts:	ENSRNOT00000013581
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	50763951	95763951	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	51589699	99045312	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	44477926	89477926	Rat
4889938	Bss89	Bone structure and strength QTL 89	3.8		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	8	58991697	91341052	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	63404444	108404444	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	47541419	92541419	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	44447837	89447837	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	49610204	94610204	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
1582254	Kidm31	Kidney mass QTL 31	3		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	8	49245178	94245178	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
10402857	Bp380	Blood pressure QTL 380		0.95	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1582243	Bw66	Body weight QTL 66	3.4	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	8	49245178	94245178	Rat
5684973	Bss100	Bone structure and strength QTL 100	4.7		tibia area (VT:1000281)	tibia area measurement (CMO:0001382)	8	58991697	91341052	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	44475043	89475043	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	62848139	107848139	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	58337123	103337123	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	62848139	107848139	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	62970527	107970527	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	62848139	107848139	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	62848139	107848139	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	62848139	107848139	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	62848139	107848139	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	60248093	105248093	Rat
2313086	Bss60	Bone structure and strength QTL 60	4.1	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	8	58991697	91341052	Rat
2293697	Bmd39	Bone mineral density QTL 39			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	8	62848139	107848139	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	55428416	107963099	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	62963099	107963099	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
2301402	Bp316	Blood pressure QTL 316		0.005	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
631664	Hcar3	Hepatocarcinoma resistance QTL 3	2.9	0.0005	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	8	62982864	107982864	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AW141789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CA339823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK478034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CN544531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV126532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN956151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DV714248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY312590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013581 ⟹ ENSRNOP00000013581

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	68,673,200 - 68,775,572 (-)	Ensembl
mRatBN7.2 Ensembl	8	59,777,379 - 59,879,762 (-)	Ensembl
Rnor_6.0 Ensembl	8	64,166,360 - 64,268,555 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084758 ⟹ ENSRNOP00000075350

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	68,676,211 - 68,775,572 (-)	Ensembl
mRatBN7.2 Ensembl	8	59,780,390 - 59,879,762 (-)	Ensembl
Rnor_6.0 Ensembl	8	64,169,371 - 64,268,555 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098010 ⟹ ENSRNOP00000081863

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	68,673,200 - 68,775,572 (-)	Ensembl
mRatBN7.2 Ensembl	8	59,777,379 - 59,880,245 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105064 ⟹ ENSRNOP00000091018

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	68,685,564 - 68,775,572 (-)	Ensembl
mRatBN7.2 Ensembl	8	59,789,746 - 59,879,762 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118605 ⟹ ENSRNOP00000083846

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	68,673,200 - 68,775,301 (-)	Ensembl
mRatBN7.2 Ensembl	8	59,777,379 - 59,879,491 (-)	Ensembl

RefSeq Acc Id:

NM_001013108 ⟹ NP_001013126

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	68,673,199 - 68,775,572 (-)	NCBI
mRatBN7.2	8	59,777,378 - 59,879,762 (-)	NCBI
Rnor_6.0	8	64,166,359 - 64,268,555 (-)	NCBI
Rnor_5.0	8	63,928,309 - 64,030,505 (-)	NCBI
RGSC_v3.4	8	63,201,871 - 63,305,302 (-)	RGD
Celera	8	59,219,248 - 59,321,584 (-)	RGD

Sequence:

show sequence

CTGTTTTCCGTCCGAGCCCGGAGCGGAGCGGCGTCTGATTGAGGCCGGCAGTAAGCGGCCCCCG
CGCTCCCTCCCGCTCTGCTCCGCGCCCTCCCGGCCGCCGCCGCCGCCCGCCTCCAACCGCCGCA
CCCGGGGAGCAGCCGCGGCCCACGGGGCCGGAACCAGGCCTGCGTCCGGACAGCAGCCGGAGCC
GGAGCGAGAGCCGGGGCCTCGGCGTCCCCGCCCTCTCCGCGCCGCGGCCAGCGTCTGCCAGGCC
CGCGCGCGTCGCGCCATGGACTCGGACGAGGGCTACAACTACGAGTTCGACGAGGACGAGGAGT
GCAGCGAGGAGGACAGCGGCGCCGAGGAGGAGGAGGACGACGACGAGGATGAGCCGGACGATGA
TAACCTGGATCTCGGCGAGGTGGAGCTGGTGGAGCCCGGGCTGGGCGTCGGCGGGGAGCGGGAC
GGACTGCTGTGCGGGGAGACTGGCGGCGGCGGCGGCAGCGCTCTGGGTCCCGGAGGCGGTGGCG
GCGGTGGCGGTGGCGGCGGCGGCCCGGGGCACGAGCAGGAGGAAGATTACCGCTACGAGGTGCT
CACGGCCGAACAGATCCTGCAGCACATGGTGGAATGTATCCGGGAGGTCAACGAGGTCATCCAG
AATCCAGCAACTATCACGAGAATACTCCTTAGCCACTTCAATTGGGATAAAGAGAAGCTAATGG
AAAGGTACTTTGATGGAAACCTGGAGAAGCTCTTTGCTGAGTGTCATGTAATTAATCCAAGTAA
AAAGTCTCGAACTCGCCAGATGAATACAAGGTCATCAGCACAGGATATGCCTTGTCAGATCTGC
TACTTGAATTACCCTAACTCGTATTTTACTGGCCTTGAATGTGGACATAAGTTTTGTATGCAGT
GCTGGAGTGAATATTTAACTACCAAAATAATGGAAGAAGGCATGGGGCAGACTATCTCGTGTCC
TGCGCATGGCTGTGATATCTTAGTGGATGACAACACAGTTATGCGCCTGATCACAGATTCAAAA
GTTAAATTAAAATATCAGCATTTAATAACAAATAGCTTTGTAGAGTGCAACCGACTGTTAAAAT
GGTGTCCTGCCCCCGATTGCCACCATGTTGTTAAAGTCCAGTATCCTGATGCAAAACCAGTTCG
CTGCAAGTGTGGCCGCCAGTTTTGCTTTAACTGTGGCGAAAATTGGCATGATCCAGTTAAATGT
AAGTGGTTGAAGAAGTGGATTAAAAAGTGTGATGATGACAGTGAAACTTCTAATTGGATTGCAG
CTAACACAAAGGAATGTCCCAAATGCCATGTCACAATTGAGAAGGATGGTGGTTGTAATCACAT
GGTCTGTCGTAACCAGAACTGTAAAGCAGAGTTTTGCTGGGTGTGTCTTGGCCCTTGGGAACCA
CATGGATCTGCCTGGTACAACTGTAACCGCTATAATGAGGATGATGCAAAGGCAGCAAGAGATG
CCCAAGAGCGATCTAGGGCAGCCCTGCAGAGGTACCTGTTCTACTGTAATCGCTATATGAACCA
CATGCAGAGTCTACGCTTTGAGCATAAGCTGTATGCTCAGGTGAAACAGAAGATGGAGGAAATG
CAGCAGCACAACATGTCCTGGATTGAGGTGCAGTTCCTGAAGAAAGCAGTTGATGTCCTCTGCC
AGTGTCGTGCCACACTCATGTACACTTATGTCTTCGCTTTCTACCTCAAAAAGAATAACCAGTC
CATTATCTTTGAGAATAATCAAGCAGATCTAGAAAATGCCACAGAGGTGCTTTCGGGCTACCTT
GAACGAGATATTTCCCAAGATTCTCTGCAAGATATAAAGCAGAAAGTCCAAGATAAGTACAGAT
ACTGTGAGAGTCGACGAAGGGTTTTGTTACAGCATGTGCATGAAGGCTATGAAAAAGATCTGTG
GGAGTACATTGAGGACTGAGCCTGGCCCTGCATAAAATGAACTCTGAAAACTTTACCATCTAGA
GTGCTCATGCAATTAAAACAAACACAAACAAGGAGGCACTAAGCCTGTTCTGACACCGCTGGTC
TCTAGTACCAGAATTCTGTTTTGTTAACGGAAAGTTTAAGTAAATTATATTGTAATAAAAAAGG
TAGATAAACCATTGTACAACAGTATTCTAGGCCGCCAACAGTGTGACAGACACACAAAAGCCCT
CCAACTCTAACTTGTAACGTAGCTTCATTCTCAAAGCTGACTTCCTTTTCTTCTTCCTGAGTGT
AGTACAGTTAAACATTCAGACAGCTCCTCGACACTGCTTTTCATGTCCAAACCAGCCATTTCGT
TGTACTTTGGTAAAGGACCTCTTCCCCTTCCTGCCCTGCACATACACACCTCCACACACAGTTT
CACTTTCTCTCATACCCTAAGGTCATGAGTGAATAATGATTATTAGCTACTTGTAAAGGAAATT
CTTGGGAGGGAGAAGGGGGTAGGCAGCAAGAGGATTAAACAAAAAACACAAAAACTTTGTATAT
GACTTTTAAAACAAGAGGACAACACAGTATTTTTCAAAATTGTATATAGCGCATATGCATGGAT
AAAGCAAGCGTGGCACGTGTTTGCATAATGTTTAATTACAAAAATATTTATTCTTTAAAAAGCT
TCAAGATTATGTCTATTTGCTGTGCATTTTCTTTCAGTTGGCTTTATCTTTCCAGGGTTGGGTT
GGGATAAAGGTGTTTGTTAAGCCCCTCTGCAAGACCTAACTAGAGTGCTTTCCCCTTCCTGAGG
TCAGTTTGCCCGCTGTGGTTTGGTTGTATCTTTTGCTGGCCATGGGCCTCATGCCTAGAATTCT
CAGCTTCTGGATCTAGATCCAGGAAGTCAAGTTCTAAGCAAATGGCTTGGTCTGTTAAAGGGTT
TAGTTGCTTCAATTCATGAATGATCCTATCCCAACCTACTCCTCAGTGGCCTTGATGTCCCCAT
TTTAGCCTGTGTGCCCATGCCATGCACACAGCGTAGGCTTTCTAGGATCCCCATCAAGTCTGGA
GGAGGCATTTCAAAATCTCCTGTTTTATTTTTCCTGAATTGCTGCTTTGAGCCTTTTAAGTTTT
TAGTTCTGGCTCGTCTTTCATCCCTTCTTTATGTTAGGGTGTTGAATACAATGTTTTCACTTTA
AATATAAATAAATAGCCATTCACTTAGTCTGAGATTGTGGATTAAAATGGTGGATACTGAAATT
ACTCGTGTGTGTTGCGGTGGGTTCAGTTTGAAGGCAAACACCACTAGAATATGATACTCCCATC
CAGTGCATTTGAGTAGGAATCACTGAGTTTGCTTCTTTTCTATTGTCAGCATATAGGAGAATAA
TGCATTTTAGCTGTGATGTCCATTTTTATGAAATTTCTACTAAAAGCTATGTTAAAAGTAAAGG
GTGGTGGTGGTTTTATTAACTATATACTTGTTTAGGCCATTCTGCCTGTGGTATTTTTCAACAG
GTCAGCATCCCTAAGACTGTCAGTTTTATATAAGAGTGCAGAGTGAACTAGGCAACTAGATCAA
GAGGTAAAACTGTTAAATGCCAGCTTTGGCTGAGGACCTCTTTGTCTTCCTTTAACTGTCTTGT
GCCTAGGGAGTGTTTACCATTTGTGAGGCAGCTGTGTCTGTTCTTGCATTGTACATCTTCTTAC
TCCATTGGGAAGTAGGCTCACTTTCCTCTGGCCTTTTGCCTAAGTTAGGCTTTGCTGAATCACC
CTACTTTTCCTTTTAGAAAGGTTGTTACATGAGATGCACTTGCAACTGTTCTTTTCCCATCAAA
AATCAGTGAATGTTTGCTGAGTATATTATGCTGCTTCCTTAAACCACTTGTCGCTTTAGGATCA
ACTTGTATTTTTTTTCTTCCCTTTCCTTGTCACCTCAGGTGGCAAATCTGAAGTCAAGTGTCTG
TTTTCCATCCTCTCTTTGTCCTATCATTCTCCATTATCCATTTGACTTTATTTCAAATAATTGC
ACCGATCTTAAGACATTTATCAAAACCAACGAGATTTCAAAGAAAGCTCAAGTATGTTCCTTTT
CCTGGTGACTTTGAAAAGCAACCAGAATTGTCACATAGACTTGTGGTCCCTTAAAATGCTTTGT
GTGTGTTGTTTAAAAAGAGTTAACTTCACATTATCTAGGTCTGAGTGTCATAAGTTCTCTTCAT
TCCCTGCCCTGCAACAAGCGTCTAAAAAGAGTGCATCTCATAGTCTCAGTCTCCCACCATGGAG
GGATAGTGTAGTTGGTGACACTTTCTAGTCCCAGTGCTCACATGGGACCTGAGGATATTGCACT
CACAATTTGTGTGGATCAAGGTGAACTGGCCCTTCTGCTACATCCAAGTTTTTAACAACCGTCT
CCATATCTGACAGCATTTCCAGAATTTACCTGCTTCTGTCAGTAGCTAGCTTCAGTGCTCCCAT
CTGGGACAGGCAAGCCATATTGTTAACAGCTTCCCTATTTGACCTACCTAAGTCTCTCAGAGGG
CTCTACTTACACATCAGGGTCTCCCTGTGGTGTTGAGATCAGTTACATTGTCAGTGCATGCATC
ATTTGAGCAATTCATTGAGCAACAGGTGAATTTTCAATGATTTACAATAAAATTTTGATCCAAA
GCTCAGGAGACATACCATAGTGGTAAATGGAGTAGCATATAACATTACCAGACTCTTAAATTCT
TTGTAATTTGCTGCAACCCAGATTGTATATGTTTTATGTGTGTTCAAATAAATATATTAAAGAC
ACACGTGTATCCATACACACAAATAGATCCAAGACTGACTTGATTTGAAATCGTTGAATCTGCA
GTGTAATGTGTGGTTCACCTGTAAGTAGGACTTGAAATTTAGAACAAGAAGAGTAAAAGGCTTA
AATGTAACAAATTCTTTTAGCTACATCCGGTATAGAGCACTTGGGGGATGGGATGGGGTGGGTT
GGTGAGACAATCAGATCGATAAATTGATTAAATGCTCCTAACCCTGTAATTTTGTGCATAGAGC
ACCTTGTGCTGTGGAAATAACTGTTCTTAGATTTTCATTGTAACTGGACTGTTCAGGTTGCCCA
GAGGGAAAGAACATTCCTAATTCTAATAAAATAAACTTTTATTTTGTTATTCCATTAAAAAAAA
AAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063265127 ⟹ XP_063121197

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	68,673,207 - 68,775,638 (-)	NCBI

RefSeq Acc Id:

XM_063265128 ⟹ XP_063121198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	68,679,724 - 68,775,648 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013126	(Get FASTA)	NCBI Sequence Viewer
	XP_063121197	(Get FASTA)	NCBI Sequence Viewer
	XP_063121198	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83881	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013581.6
	ENSRNOP00000075350
	ENSRNOP00000075350.1
	ENSRNOP00000081863
	ENSRNOP00000081863.2
	ENSRNOP00000083846.2
	ENSRNOP00000091018.1

RefSeq Acc Id:

NP_001013126 ⟸ NM_001013108

- UniProtKB:

D3ZXL1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDSDEGYNYEFDEDEECSEEDSGAEEEEDDDEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCG
ETGGGGGSALGPGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATI
TRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYP
NSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKY
QHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLKK
WIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAW
YNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNM
SWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED

hide sequence

Ensembl Acc Id:

ENSRNOP00000075350 ⟸ ENSRNOT00000084758

Ensembl Acc Id:

ENSRNOP00000013581 ⟸ ENSRNOT00000013581

Ensembl Acc Id:

ENSRNOP00000091018 ⟸ ENSRNOT00000105064

Ensembl Acc Id:

ENSRNOP00000081863 ⟸ ENSRNOT00000098010

Ensembl Acc Id:

ENSRNOP00000083846 ⟸ ENSRNOT00000118605

RefSeq Acc Id:	XP_063121197 ⟸ XM_063265127
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A015 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121198 ⟸ XM_063265128
- Peptide Label:	isoform X2
- UniProtKB:	Q5XI15 (UniProtKB/TrEMBL), A0A8I6AEU5 (UniProtKB/TrEMBL)

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZXL1-F1-model_v2	AlphaFold	D3ZXL1	1-555	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696039

Promoter ID:

EPDNEW_R6563

Type:

multiple initiation site

Name:

Arih1_1

Description:

ariadne RBR E3 ubiquitin protein ligase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	64,268,593 - 64,268,653	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308131	AgrOrtholog
BioCyc Gene	G2FUF-30247	BioCyc
Ensembl Genes	ENSRNOG00000009887	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013581.8	UniProtKB/TrEMBL
	ENSRNOT00000084758	ENTREZGENE
	ENSRNOT00000084758.3	UniProtKB/TrEMBL
	ENSRNOT00000098010	ENTREZGENE
	ENSRNOT00000098010.2	UniProtKB/TrEMBL
	ENSRNOT00000105064.2	UniProtKB/TrEMBL
	ENSRNOT00000118605.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.1750	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7131418	IMAGE-MGC_LOAD
InterPro	Ariadne	UniProtKB/TrEMBL
	ARIH1-like_UBL	UniProtKB/TrEMBL
	E3_UB_ligase_RBR	UniProtKB/TrEMBL
	Parkin-like_IBR	UniProtKB/TrEMBL
	TRIAD_supradom	UniProtKB/TrEMBL
	Znf_C3HC4_RING-type	UniProtKB/TrEMBL
	Znf_C6HC	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
KEGG Report	rno:300756	UniProtKB/TrEMBL
MGC_CLONE	MGC:95181	IMAGE-MGC_LOAD
NCBI Gene	300756	ENTREZGENE
PANTHER	PTHR11685	UniProtKB/TrEMBL
Pfam	ARI1_UBAl	UniProtKB/TrEMBL
	Ariadne	UniProtKB/TrEMBL
	IBR	UniProtKB/TrEMBL
	IBR_1	UniProtKB/TrEMBL
	IBR_2	UniProtKB/TrEMBL
	zf-C3HC4	UniProtKB/TrEMBL
	zf-C3HC4_2	UniProtKB/TrEMBL
PhenoGen	Arih1	PhenoGen
PROSITE	TRIAD	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009887	RatGTEx
SMART	IBR	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A8I5ZSJ6_RAT	UniProtKB/TrEMBL
	A0A8I6A015	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AEU5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZXL1	ENTREZGENE, UniProtKB/TrEMBL
	Q5XI15	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-11-11	Arih1	ariadne RBR E3 ubiquitin protein ligase 1	Arih1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-13	Arih1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	Arih1	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Arih1	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)	Arih1_predicted	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Arih1_predicted	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD