C15h8orf58 (similar to human chromosome 8 open reading frame 58) - Rat Genome Database

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Gene: C15h8orf58 (similar to human chromosome 8 open reading frame 58) Rattus norvegicus
Analyze
Symbol: C15h8orf58
Name: similar to human chromosome 8 open reading frame 58
RGD ID: 1308117
Description: Orthologous to human C8orf58 (chromosome 8 open reading frame 58); INTERACTS WITH bisphenol A; gentamycin; methamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC361066; LOC361066; RGD1308117; similar to 9930012K11Rik protein; uncharacterized protein C8orf58 homolog; uncharacterized protein LOC361066
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,638,336 - 51,645,141 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1551,638,350 - 51,642,974 (-)EnsemblGRCr8
mRatBN7.21545,228,615 - 45,235,274 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,228,615 - 45,233,254 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1549,346,468 - 49,351,106 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,457,962 - 50,462,600 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,317,278 - 47,321,916 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01551,834,703 - 51,841,412 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,834,703 - 51,839,341 (-)Ensemblrn6Rnor6.0
Rnor_5.01555,560,857 - 55,568,826 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41550,555,250 - 50,559,887 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1544,908,257 - 44,912,742 (-)NCBICelera
RGSC_v3.11550,571,145 - 50,575,659 (-)NCBI
Cytogenetic Map15p11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C15h8orf58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,638,336 - 51,645,141 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1551,638,350 - 51,642,974 (-)EnsemblGRCr8
mRatBN7.21545,228,615 - 45,235,274 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,228,615 - 45,233,254 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1549,346,468 - 49,351,106 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,457,962 - 50,462,600 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,317,278 - 47,321,916 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01551,834,703 - 51,841,412 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,834,703 - 51,839,341 (-)Ensemblrn6Rnor6.0
Rnor_5.01555,560,857 - 55,568,826 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41550,555,250 - 50,559,887 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1544,908,257 - 44,912,742 (-)NCBICelera
RGSC_v3.11550,571,145 - 50,575,659 (-)NCBI
Cytogenetic Map15p11NCBI
C8orf58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,599,599 - 22,604,142 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,599,594 - 22,604,150 (+)Ensemblhg38GRCh38
GRCh37822,457,112 - 22,461,655 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,513,067 - 22,517,608 (+)NCBIBuild 36Build 36hg18NCBI36
Celera821,418,974 - 21,423,515 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,999,962 - 21,004,511 (+)NCBIHuRef
CHM1_1822,659,306 - 22,663,855 (+)NCBICHM1_1
T2T-CHM13v2.0822,873,482 - 22,878,025 (+)NCBIT2T-CHM13v2.0
9930012K11Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,391,854 - 70,396,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,391,854 - 70,396,951 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381470,154,405 - 70,159,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,154,405 - 70,159,502 (-)Ensemblmm10GRCm38
MGSCv371470,554,212 - 70,559,309 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361468,889,485 - 68,901,790 (-)NCBIMGSCv36mm8
Celera1467,695,147 - 67,700,244 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.25NCBI
CUNH8orf58
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540346,023,610 - 46,026,997 (+)Ensembl
ChiLan1.0NW_00495540346,024,484 - 46,027,834 (+)NCBIChiLan1.0ChiLan1.0
C7H8orf58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2741,106,581 - 41,111,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,831,594 - 16,836,326 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,849,622 - 21,854,234 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,783,605 - 18,792,394 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,783,612 - 18,792,386 (+)EnsemblpanPan2panpan1.1
C25H8orf58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12534,674,918 - 34,679,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2534,674,756 - 34,679,454 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2535,264,666 - 35,269,097 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02534,884,475 - 34,888,907 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2534,885,313 - 34,888,858 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12534,830,924 - 34,835,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02534,685,001 - 34,689,431 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02534,840,519 - 34,844,950 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH8orf58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,229,651 - 12,235,108 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365556,336,522 - 6,340,032 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365556,336,092 - 6,340,862 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C8H8orf58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,680,207 - 20,684,351 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,680,342 - 20,684,332 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605221,542,298 - 21,546,896 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH8orf58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475818,101,772 - 18,105,212 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475818,099,118 - 18,106,056 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C12H8orf58
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11254,188,555 - 54,193,472 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C15h8orf58
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:85
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000011277
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
2306968Anxrr23Anxiety related response QTL 234.83reflex trait (VT:0001961)amplitude of the acoustic startle response (CMO:0001520)154480677352597086Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
7411725Strs7Sensitivity to stroke QTL 73.8cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)154446544756583797Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
AU016692  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,228,955 - 45,229,100 (+)MAPPERmRatBN7.2
Rnor_6.01551,835,043 - 51,835,187NCBIRnor6.0
Rnor_5.01555,561,197 - 55,561,341UniSTSRnor5.0
RGSC_v3.41550,555,589 - 50,555,733UniSTSRGSC3.4
Celera1544,908,597 - 44,908,741UniSTS
Cytogenetic Map15p11UniSTS
RH143886  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,228,876 - 45,229,003 (+)MAPPERmRatBN7.2
Rnor_6.01551,834,964 - 51,835,090NCBIRnor6.0
Rnor_5.01555,561,118 - 55,561,244UniSTSRnor5.0
RGSC_v3.41550,555,510 - 50,555,636UniSTSRGSC3.4
Celera1544,908,518 - 44,908,644UniSTS
Cytogenetic Map15p11UniSTS
UniSTS:237223  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,228,690 - 45,228,901 (+)MAPPERmRatBN7.2
Rnor_6.01551,834,779 - 51,834,988NCBIRnor6.0
Rnor_5.01555,560,933 - 55,561,142UniSTSRnor5.0
RGSC_v3.41550,555,325 - 50,555,534UniSTSRGSC3.4
Celera1544,908,333 - 44,908,542UniSTS
Cytogenetic Map15p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011277   ⟹   ENSRNOP00000011277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1551,638,350 - 51,642,974 (-)Ensembl
mRatBN7.2 Ensembl1545,228,615 - 45,233,254 (-)Ensembl
Rnor_6.0 Ensembl1551,834,703 - 51,839,341 (-)Ensembl
RefSeq Acc Id: NM_001134571   ⟹   NP_001128043
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,638,336 - 51,642,974 (-)NCBI
mRatBN7.21545,228,615 - 45,233,254 (-)NCBI
Rnor_6.01551,834,703 - 51,839,341 (-)NCBI
Rnor_5.01555,560,857 - 55,568,826 (-)NCBI
RGSC_v3.41550,555,250 - 50,559,887 (-)RGD
Celera1544,908,257 - 44,912,742 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252278   ⟹   XP_006252340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,638,345 - 51,645,141 (-)NCBI
mRatBN7.21545,228,624 - 45,235,274 (-)NCBI
Rnor_6.01551,834,704 - 51,841,412 (-)NCBI
Rnor_5.01555,560,857 - 55,568,826 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063274431   ⟹   XP_063130501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,638,345 - 51,645,141 (-)NCBI
RefSeq Acc Id: XM_063274432   ⟹   XP_063130502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,638,345 - 51,645,141 (-)NCBI
RefSeq Acc Id: NP_001128043   ⟸   NM_001134571
- UniProtKB: A6HTJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252340   ⟸   XM_006252278
- Peptide Label: isoform X3
- UniProtKB: D4A3I2 (UniProtKB/TrEMBL),   A6HTJ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011277   ⟸   ENSRNOT00000011277
RefSeq Acc Id: XP_063130502   ⟸   XM_063274432
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130501   ⟸   XM_063274431
- Peptide Label: isoform X1
Protein Domains
DUF4657

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3I2-F1-model_v2 AlphaFold D4A3I2 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308117 AgrOrtholog
BioCyc Gene G2FUF-13236 BioCyc
Ensembl Genes ENSRNOG00000008351 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011277 ENTREZGENE
  ENSRNOT00000011277.9 UniProtKB/TrEMBL
InterPro DUF4657 UniProtKB/TrEMBL
NCBI Gene 361066 ENTREZGENE
PANTHER SIMILAR TO 9930012K11RIK PROTEIN UniProtKB/TrEMBL
  SIMILAR TO 9930012K11RIK PROTEIN UniProtKB/TrEMBL
Pfam DUF4657 UniProtKB/TrEMBL
PhenoGen C15h8orf58 PhenoGen
RatGTEx ENSRNOG00000008351 RatGTEx
UniProt A6HTJ0 ENTREZGENE, UniProtKB/TrEMBL
  D4A3I2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-21 C15h8orf58  similar to human chromosome 8 open reading frame 58  RGD1308117  similar to 9930012K11Rik protein  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1308117  similar to 9930012K11Rik protein   RGD1308117_predicted  similar to 9930012K11Rik protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308117_predicted  similar to 9930012K11Rik protein (predicted)  LOC361066_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361066_predicted  similar to 9930012K11Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL