Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Zfp346 | Rat | (-)-alpha-phellandrene | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of ZFP346 mRNA | CTD | PMID:25075043 | Zfp346 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ZFP346 mRNA | CTD | PMID:32145629 | Zfp346 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Zfp346 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP346 mRNA | CTD | PMID:21570461 | Zfp346 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZFP346 mRNA | CTD | PMID:33387578 | Zfp346 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of ZNF346 mRNA | CTD | PMID:27914987 | Zfp346 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ZFP346 mRNA | CTD | PMID:26251327 | Zfp346 | Rat | aflatoxin B1 | increases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ZFP346 mRNA | CTD | PMID:19770486 | Zfp346 | Rat | alpha-phellandrene | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of ZFP346 mRNA | CTD | PMID:25075043 | Zfp346 | Rat | antirheumatic drug | increases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ZNF346 mRNA | CTD | PMID:24449571 | Zfp346 | Rat | aristolochic acid A | increases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ZNF346 mRNA | CTD | PMID:33212167 | Zfp346 | Rat | arsane | affects methylation | ISO | ZNF346 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF346 gene | CTD | PMID:25304211 | Zfp346 | Rat | arsenic atom | affects methylation | ISO | ZNF346 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF346 gene | CTD | PMID:25304211 | Zfp346 | Rat | atrazine | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ZNF346 mRNA | CTD | PMID:22378314 | Zfp346 | Rat | benzo[a]pyrene | increases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ZFP346 mRNA | CTD | PMID:22228805 | Zfp346 | Rat | benzo[a]pyrene | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of ZFP346 mRNA | CTD | PMID:27858113 | Zfp346 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of ZFP346 mRNA | CTD | PMID:27858113 | Zfp346 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ZNF346 mRNA | CTD | PMID:25181051 | Zfp346 | Rat | bisphenol A | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ZNF346 gene | CTD | PMID:31601247 | Zfp346 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZFP346 mRNA | CTD | PMID:34947998 | Zfp346 | Rat | bisphenol A | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ZNF346 mRNA | CTD | PMID:29275510 | Zfp346 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of ZFP346 promoter | CTD | PMID:22457795 | Zfp346 | Rat | cannabidiol | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of ZNF346 mRNA | CTD | PMID:33244087 | Zfp346 | Rat | carbon nanotube | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of ZFP346 mRNA | CTD | PMID:25554681 | Zfp346 | Rat | chloroprene | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of ZFP346 mRNA | CTD | PMID:23125180 | Zfp346 | Rat | choline | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ZFP346 gene | CTD | PMID:20938992 | Zfp346 | Rat | chrysene | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of ZFP346 mRNA | CTD | PMID:27858113 | Zfp346 | Rat | Dibutyl phosphate | affects expression | ISO | ZNF346 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ZNF346 mRNA | CTD | PMID:37042841 | Zfp346 | Rat | dibutyl phthalate | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of ZFP346 mRNA | CTD | PMID:21266533 | Zfp346 | Rat | diclofenac | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Diclofenac results in decreased expression of ZFP346 mRNA | CTD | PMID:35537566 | Zfp346 | Rat | dorsomorphin | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF346 mRNA | CTD | PMID:27188386 | Zfp346 | Rat | enzyme inhibitor | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ZNF346 protein | CTD | PMID:23301498 | Zfp346 | Rat | folic acid | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ZFP346 gene | CTD | PMID:20938992 | Zfp346 | Rat | folic acid | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ZFP346 mRNA | CTD | PMID:25629700 | Zfp346 | Rat | fulvestrant | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ZNF346 gene | CTD | PMID:31601247 | Zfp346 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ZFP346 mRNA | CTD | PMID:33387578 | Zfp346 | Rat | inulin | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ZFP346 mRNA | CTD | PMID:36331819 | Zfp346 | Rat | isoprenaline | increases expression | ISO | Zfp346 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of ZFP346 mRNA | CTD | PMID:20003209 | Zfp346 | Rat | ivermectin | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ZNF346 protein | CTD | PMID:32959892 | Zfp346 | Rat | L-methionine | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ZFP346 gene | CTD | PMID:20938992 | Zfp346 | Rat | maneb | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ZFP346 mRNA | CTD | PMID:36117858 | Zfp346 | Rat | ozone | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ZFP346 mRNA | CTD | PMID:34911549 | Zfp346 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ZFP346 mRNA | CTD | PMID:33387578 | Zfp346 | Rat | paraquat | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ZFP346 mRNA | CTD | PMID:36117858 | Zfp346 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ZFP346 mRNA | CTD | PMID:36331819 | Zfp346 | Rat | SB 431542 | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF346 mRNA | CTD | PMID:27188386 | Zfp346 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ZFP346 mRNA | CTD | PMID:19281266 | Zfp346 | Rat | T-2 toxin | increases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | T-2 Toxin results in increased expression of ZNF346 mRNA | CTD | PMID:34581912 | Zfp346 | Rat | tetraphene | increases expression | ISO | Zfp346 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of ZFP346 mRNA | CTD | PMID:26377693 | Zfp346 | Rat | tetraphene | multiple interactions | ISO | Zfp346 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of ZFP346 mRNA | CTD | PMID:27858113 | Zfp346 | Rat | titanium dioxide | increases expression | ISO | Zfp346 (Mus musculus) | 6480464 | titanium dioxide analog results in increased expression of ZFP346 mRNA | CTD | PMID:25111187 | Zfp346 | Rat | triphenyl phosphate | affects expression | ISO | ZNF346 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ZNF346 mRNA | CTD | PMID:37042841 | Zfp346 | Rat | triptonide | affects expression | ISO | Zfp346 (Mus musculus) | 6480464 | triptonide affects the expression of ZFP346 mRNA | CTD | PMID:33045310 | Zfp346 | Rat | trovafloxacin | decreases expression | ISO | Zfp346 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ZFP346 mRNA | CTD | PMID:35537566 | Zfp346 | Rat | valproic acid | affects expression | ISO | Zfp346 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ZFP346 mRNA | CTD | PMID:17292431 | Zfp346 | Rat | valproic acid | multiple interactions | ISO | ZNF346 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF346 mRNA | CTD | PMID:27188386 | Zfp346 | Rat | valproic acid | decreases expression | ISO | ZNF346 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZNF346 mRNA | CTD | PMID:23179753 more ... | Zfp346 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of ZFP346 mRNA | CTD | PMID:20566332 | |