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Gene: Nfkbid (NFKB inhibitor delta) Rattus norvegicus

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Symbol:

Nfkbid

Name:

NFKB inhibitor delta

RGD ID:

1308055

Description:

Predicted to enable NF-kappaB binding activity. Predicted to be involved in T cell receptor signaling pathway; positive regulation of T-helper 17 cell differentiation; and regulation of gene expression. Predicted to act upstream of or within negative regulation of T cell differentiation in thymus; negative regulation of canonical NF-kappaB signal transduction; and positive regulation of thymocyte apoptotic process. Predicted to be active in nucleus. Orthologous to human NFKBID (NFKB inhibitor delta); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC308496; NF-kappa-B inhibitor delta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; RGD1308055; similar to T-cell activation NFKB-like protein; T-cell activation NFKB-like protein; Ta-nfkbh

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NFKBID (NFKB inhibitor delta)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Nfkbid (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nfkbid (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NFKBID (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NFKBID (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nfkbid (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NFKBID (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NFKBID (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nfkbid (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nfkbid (NFKB inhibitor delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Nfkbid (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nfkbid (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NFKBID (NFKB inhibitor delta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NFKBID (NFKB inhibitor delta)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nfki-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector)
Xenopus tropicalis (tropical clawed frog):	nfkbid	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	94,808,459 - 94,824,726 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	94,808,453 - 94,817,861 (+)	Ensembl				GRCr8
mRatBN7.2	1	85,679,353 - 85,690,415 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	85,680,861 - 85,690,447 (+)	Ensembl				mRatBN7.2
Rnor_6.0	1	88,883,816 - 88,892,543 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	88,885,937 - 88,892,615 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	90,039,481 - 90,048,087 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	85,374,259 - 85,383,179 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	80,052,701 - 80,061,438 (+)	NCBI		Celera
RGSC_v3.1	1	85,451,333 - 85,461,546 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

common variable immunodeficiency 12 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-palmitoylglycerol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amosite asbestos (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

C.I. Natural Red 20 (ISO)

cadmium dichloride (ISO)

Calcimycin (ISO)

carbon nanotube (ISO)

casticin (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dieldrin (ISO)

fructose (ISO)

glucose (ISO)

glyphosate (ISO)

gold atom (ISO)

gold(0) (ISO)

Licochalcone B (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

nickel atom (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

serpentine asbestos (ISO)

Shikonin (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

testosterone (EXP)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

inflammatory response (IEA)

negative regulation of canonical NF-kappaB signal transduction (ISO)

negative regulation of T cell differentiation in thymus (ISO)

obsolete negative regulation of NF-kappaB transcription factor activity (ISO)

positive regulation of T-helper 17 cell differentiation (ISO)

positive regulation of thymocyte apoptotic process (ISO)

regulation of gene expression (IBA)

T cell receptor signaling pathway (ISO)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

NF-kappaB binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11931770	PMID:25282160

Genomics

Comparative Map Data

Nfkbid
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	94,808,459 - 94,824,726 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	94,808,453 - 94,817,861 (+)	Ensembl				GRCr8
mRatBN7.2	1	85,679,353 - 85,690,415 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	85,680,861 - 85,690,447 (+)	Ensembl				mRatBN7.2
Rnor_6.0	1	88,883,816 - 88,892,543 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	88,885,937 - 88,892,615 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	90,039,481 - 90,048,087 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	85,374,259 - 85,383,179 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	80,052,701 - 80,061,438 (+)	NCBI		Celera
RGSC_v3.1	1	85,451,333 - 85,461,546 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

NFKBID
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	35,887,952 - 35,902,303 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	35,887,630 - 35,902,303 (-)	Ensembl			hg38	GRCh38
GRCh37	19	36,378,854 - 36,393,205 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	41,070,983 - 41,083,392 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	33,093,331 - 33,105,743 (-)	NCBI		Celera
Cytogenetic Map	19	q13.12	NCBI
HuRef	19	32,884,386 - 32,896,797 (-)	NCBI		HuRef
CHM1_1	19	36,380,424 - 36,392,833 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	38,433,711 - 38,448,068 (-)	NCBI		T2T-CHM13v2.0

Nfkbid
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	30,121,156 - 30,128,173 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	30,121,157 - 30,128,171 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	30,421,731 - 30,428,749 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	30,421,732 - 30,428,746 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	31,208,323 - 31,213,765 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	30,132,064 - 30,137,506 (+)	NCBI		MGSCv36	mm8
Celera	7	25,015,002 - 25,020,443 (+)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	17.52	NCBI

Nfkbid
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	2,680,806 - 2,689,155 (+)	Ensembl
ChiLan1.0	NW_004955468	2,680,934 - 2,688,797 (+)	NCBI	ChiLan1.0	ChiLan1.0

NFKBID
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	41,887,097 - 41,900,701 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	43,864,145 - 43,883,737 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	32,805,772 - 32,817,778 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	41,553,727 - 41,565,216 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	41,553,727 - 41,568,555 (-)	Ensembl			panPan2	panpan1.1

NFKBID
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	116,763,371 - 116,770,683 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	116,757,289 - 116,772,325 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	116,168,829 - 116,176,249 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	117,366,444 - 117,373,869 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	117,366,573 - 117,374,251 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	116,930,000 - 116,937,419 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	116,553,532 - 116,560,938 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	117,609,295 - 117,616,723 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nfkbid
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	11,174,549 - 11,181,459 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936570	463,974 - 471,344 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936570	464,513 - 471,333 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NFKBID
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	45,298,288 - 45,306,316 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	45,298,289 - 45,307,471 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	40,700,968 - 40,708,833 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NFKBID
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	30,800,122 - 30,812,991 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	30,799,204 - 30,811,141 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	8,592,871 - 8,607,362 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nfkbid
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	10,168,792 - 10,179,510 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624794	10,172,789 - 10,180,693 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nfkbid
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	165,572,910 - 165,580,159 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nfkbid
44 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	26
Count of miRNA genes:	24
Interacting mature miRNAs:	26
Transcripts:	ENSRNOT00000029719
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	92963855	109494029	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	8	66	165	91	90	59	92	59	6	351	191	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001435836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003748825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029719 ⟹ ENSRNOP00000037384

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	94,808,453 - 94,817,861 (+)	Ensembl
mRatBN7.2 Ensembl	1	85,680,861 - 85,690,447 (+)	Ensembl
Rnor_6.0 Ensembl	1	88,885,937 - 88,892,615 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000142341 ⟹ ENSRNOP00000104633

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	94,809,134 - 94,817,861 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000157888 ⟹ ENSRNOP00000110642

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	94,809,120 - 94,817,861 (+)	Ensembl

RefSeq Acc Id:

XM_039093862 ⟹ XP_038949790

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,459 - 94,824,726 (+)	NCBI
mRatBN7.2	1	85,680,544 - 85,690,415 (+)	NCBI

RefSeq Acc Id:

XM_063277834 ⟹ XP_063133904

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,566 - 94,824,726 (+)	NCBI

RefSeq Acc Id:

XR_010059969

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,565 - 94,817,271 (+)	NCBI

RefSeq Acc Id:

XR_010059970

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,565 - 94,817,271 (+)	NCBI

RefSeq Acc Id:

XR_010059971

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,565 - 94,817,271 (+)	NCBI

RefSeq Acc Id:

XR_010059972

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,567 - 94,817,215 (+)	NCBI

RefSeq Acc Id:

XR_010059974

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	94,808,565 - 94,817,275 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001422765	(Get FASTA)	NCBI Sequence Viewer
	XP_038949790	(Get FASTA)	NCBI Sequence Viewer
	XP_063133904	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07761	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037384.5
	ENSRNOP00000104633
	ENSRNOP00000104633.1
	ENSRNOP00000110642.1

Ensembl Acc Id:

ENSRNOP00000037384 ⟸ ENSRNOT00000029719

RefSeq Acc Id:	XP_038949790 ⟸ XM_039093862
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063133904 ⟸ XM_063277834
- Peptide Label:	isoform X1
- UniProtKB:	A6J9X3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000110642 ⟸ ENSRNOT00000157888

Ensembl Acc Id:

ENSRNOP00000104633 ⟸ ENSRNOT00000142341

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M2B5-F1-model_v2	AlphaFold	F1M2B5	1-327	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689916

Promoter ID:

EPDNEW_R439

Type:

single initiation site

Name:

Nfkbid_1

Description:

NFKB inhibitor delta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	88,885,964 - 88,886,024	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308055	AgrOrtholog
BioCyc Gene	G2FUF-60111	BioCyc
Ensembl Genes	ENSRNOG00000025111	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000029719.6	UniProtKB/TrEMBL
	ENSRNOT00000142341	ENTREZGENE
	ENSRNOT00000142341.1	UniProtKB/TrEMBL
	ENSRNOT00000157888.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
NCBI Gene	308496	ENTREZGENE
PANTHER	ANKYRIN REPEAT FAMILY A	UniProtKB/TrEMBL
	NF-KAPPA-B INHIBITOR DELTA	UniProtKB/TrEMBL
Pfam	Ank_2	UniProtKB/TrEMBL
PhenoGen	Nfkbid	PhenoGen
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025111	RatGTEx
SMART	ANK	UniProtKB/TrEMBL
Superfamily-SCOP	ANK	UniProtKB/TrEMBL
UniProt	A0ABK0LJL5_RAT	UniProtKB/TrEMBL
	A0ABK0M804_RAT	UniProtKB/TrEMBL
	A6J9X3	ENTREZGENE, UniProtKB/TrEMBL
	F1M2B5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-01	Nfkbid	NFKB inhibitor delta	Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-02	Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	Ta-nfkbh	T-cell activation NFKB-like protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Ta-nfkbh	T-cell activation NFKB-like protein	RGD1308055_predicted	similar to T-cell activation NFKB-like protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1308055_predicted	similar to T-cell activation NFKB-like protein (predicted)	LOC308496_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC308496_predicted	similar to T-cell activation NFKB-like protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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