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Gene: Prkd2 (protein kinase D2) Rattus norvegicus

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Symbol:

Prkd2

Name:

protein kinase D2

RGD ID:

1308054

Description:

Predicted to enable protein kinase C binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including positive regulation of endothelial cell migration; positive regulation of macromolecule biosynthetic process; and positive regulation of signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Orthologous to human PRKD2 (protein kinase D2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292658; nPKC-D2; RGD1308054; serine/threonine-protein kinase D2; similar to protein kinase D2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRKD2 (protein kinase D2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Prkd2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prkd2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRKD2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRKD2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prkd2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRKD2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRKD2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prkd2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Prkd2 (protein kinase D2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PRKD2 (protein kinase D2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Prkd2 (protein kinase D2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	prkd2 (protein kinase D2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	prkd2 (protein kinase D2)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	dkf-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	PKD	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dkf-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dkf-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,640,095 - 86,670,476 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,642,629 - 86,670,675 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,513,625 - 77,542,386 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,513,986 - 77,542,376 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	82,894,204 - 82,922,473 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,458,248 - 91,486,518 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,649,293 - 84,677,564 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,767,911 - 78,796,223 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,767,911 - 78,796,231 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,015,106 - 80,043,535 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,168,290 - 77,197,277 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	71,999,137 - 72,027,468 (+)	NCBI		Celera
RGSC_v3.1	1	77,246,400 - 77,275,388 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

B-Cell Chronic Lymphocytic Leukemia (ISO)

polycystic ovary syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

bafilomycin A1 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP)

C60 fullerene (EXP)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

carboplatin (ISO)

chloroquine (ISO)

cisplatin (ISO)

clotrimazole (EXP)

coumarin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

diazinon (ISO)

dicrotophos (ISO)

dioxygen (ISO)

diuron (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

erastin (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

fipronil (EXP)

FR900359 (ISO)

lipopolysaccharide (ISO)

malonaldehyde (ISO)

methamphetamine (EXP)

methidathion (ISO)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

motexafin gadolinium (ISO)

N-methyl-4-phenylpyridinium (ISO)

nitrates (ISO)

ozone (ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phorbol 13-acetate 12-myristate (ISO)

selenium atom (ISO)

sirolimus (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

sulfadimethoxine (EXP)

thimerosal (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc acetate (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adaptive immune response (IEA)

angiogenesis (IEA)

cell adhesion (IEA)

cellular response to vascular endothelial growth factor stimulus (IEA,ISO)

immune system process (IEA)

intracellular signal transduction (IBA,IEA,ISO)

phospholipase C-activating G protein-coupled receptor signaling pathway (IBA)

positive regulation of angiogenesis (IEA,ISO,ISS)

positive regulation of blood vessel endothelial cell migration (IEA,ISO)

positive regulation of cell adhesion (IEA,ISO,ISS)

positive regulation of cell communication (IEA)

positive regulation of DNA biosynthetic process (IEA,ISO,ISS)

positive regulation of endothelial cell chemotaxis (IEA,ISO)

positive regulation of endothelial cell migration (IEA,ISO,ISS)

positive regulation of endothelial cell proliferation (IEA,ISO,ISS)

positive regulation of ERK1 and ERK2 cascade (IEA,ISO,ISS)

positive regulation of fibroblast growth factor receptor signaling pathway (IEA,ISO,ISS)

positive regulation of interleukin-2 production (IEA,ISO,ISS)

positive regulation of interleukin-8 production (IEA,ISO,ISS)

positive regulation of signaling (IEA)

positive regulation of T cell receptor signaling pathway (IEA,ISO,ISS)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of vascular endothelial growth factor receptor signaling pathway (IEA,ISO,ISS)

protein phosphorylation (ISO)

regulation of T cell apoptotic process (IEA,ISO)

T cell receptor signaling pathway (IEA,ISO)

vascular endothelial growth factor receptor signaling pathway (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IBA,IEA,ISO)

Golgi apparatus (IEA)

membrane (IEA)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

plasma membrane (IEA)

Molecular Function

ATP binding (IEA)

diacylglycerol-dependent serine/threonine kinase activity (IEA)

kinase activity (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA,ISO)

protein kinase C binding (IEA,ISO)

protein serine kinase activity (IEA,ISO)

protein serine/threonine kinase activity (IBA,IEA,ISO)

transferase activity (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:15604256	PMID:16641100	PMID:16928771	PMID:17077180	PMID:17226786	PMID:17951978	PMID:18059339	PMID:18440775	PMID:19001381	PMID:19192391	PMID:20497126
PMID:20819079	PMID:22228765	PMID:27369082	PMID:28428613

Genomics

Comparative Map Data

Prkd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,640,095 - 86,670,476 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,642,629 - 86,670,675 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,513,625 - 77,542,386 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,513,986 - 77,542,376 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	82,894,204 - 82,922,473 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,458,248 - 91,486,518 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,649,293 - 84,677,564 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,767,911 - 78,796,223 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,767,911 - 78,796,231 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,015,106 - 80,043,535 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,168,290 - 77,197,277 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	71,999,137 - 72,027,468 (+)	NCBI		Celera
RGSC_v3.1	1	77,246,400 - 77,275,388 (+)	NCBI
Cytogenetic Map	1	q21	NCBI

PRKD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	46,674,316 - 46,717,114 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	46,674,275 - 46,717,127 (-)	Ensembl			hg38	GRCh38
GRCh37	19	47,177,573 - 47,220,371 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	51,869,413 - 51,912,224 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	51,869,412 - 51,911,506	NCBI
Celera	19	43,981,103 - 44,023,914 (-)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	43,602,696 - 43,645,312 (-)	NCBI		HuRef
CHM1_1	19	47,179,449 - 47,222,284 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	49,499,855 - 49,545,002 (-)	NCBI		T2T-CHM13v2.0

Prkd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	16,576,827 - 16,604,386 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	16,576,827 - 16,604,389 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	16,842,902 - 16,870,461 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	16,842,902 - 16,870,464 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	17,428,414 - 17,455,810 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	16,001,587 - 16,028,983 (+)	NCBI		MGSCv36	mm8
Celera	7	14,041,053 - 14,076,870 (+)	NCBI		Celera
Cytogenetic Map	7	A2	NCBI
cM Map	7	9.15	NCBI

Prkd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955574	723,933 - 750,793 (-)	Ensembl
ChiLan1.0	NW_004955574	723,933 - 750,794 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRKD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	52,824,032 - 52,868,739 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	54,694,894 - 54,739,621 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	43,666,591 - 43,710,858 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	52,195,096 - 52,238,758 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	52,195,303 - 52,237,731 (-)	Ensembl			panPan2	panpan1.1

PRKD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	109,206,400 - 109,241,529 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	109,207,067 - 109,330,007 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	108,686,213 - 108,721,121 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	109,732,886 - 109,767,802 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	109,732,806 - 109,767,767 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	109,410,008 - 109,444,923 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	109,044,199 - 109,079,115 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	109,912,894 - 109,947,820 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Prkd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	18,906,807 - 18,933,390 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	522,910 - 551,469 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	524,532 - 551,451 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRKD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	52,559,393 - 52,599,132 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	52,559,066 - 52,599,174 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	47,880,007 - 47,919,799 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRKD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	40,028,214 - 40,071,523 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	40,027,552 - 40,071,455 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	19,740,729 - 19,783,637 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prkd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	6,886,327 - 6,915,179 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624832	6,885,627 - 6,915,316 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Prkd2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	172,221,345 - 172,250,017 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Prkd2
169 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	278
Count of miRNA genes:	184
Interacting mature miRNAs:	207
Transcripts:	ENSRNOT00000022360
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022360 ⟹ ENSRNOP00000022360

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,642,629 - 86,670,470 (+)	Ensembl
mRatBN7.2 Ensembl	1	77,513,986 - 77,542,376 (+)	Ensembl
Rnor_6.0 Ensembl	1	78,767,911 - 78,796,231 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117563 ⟹ ENSRNOP00000096969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,642,629 - 86,670,470 (+)	Ensembl
mRatBN7.2 Ensembl	1	77,513,986 - 77,542,376 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000136993 ⟹ ENSRNOP00000101544

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,642,629 - 86,670,675 (+)	Ensembl

RefSeq Acc Id:

NM_001013895 ⟹ NP_001013917

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,642,174 - 86,670,462 (+)	NCBI
mRatBN7.2	1	77,514,077 - 77,542,368 (+)	NCBI
Rnor_6.0	1	78,767,911 - 78,796,223 (+)	NCBI
Rnor_5.0	1	80,015,106 - 80,043,535 (+)	NCBI
RGSC_v3.4	1	77,168,290 - 77,197,277 (+)	RGD
Celera	1	71,999,137 - 72,027,468 (+)	RGD

Sequence:

show sequence

CCGCCCCGCCTTCGGATCCCGCCATCCTCGAGTCTCTCAACCTGACAGATTTCTCTCTCAAATG
CCTGGGTTCTTACCACCACCGCGCGAGAGCTCTCGGATCTAGGTCCCAGGTTCCTCGGTGAGCT
CTGGGCGGCAGGTCGGGGTCTGGCCCCAATGGCCGCCGCCCCCTCCCATCCCGCCGGACTCCCC
TGCTCTCCGGGGCCCGGGTCTCCTCCGCCCCCCGGTGGCTCGGATCTCCAGTCTCTGCCACCTC
TGCTGCCTCAGATCCCTGCTCCGGGATCGGGGGTCTCCTTCCACATCCAGATCGGATTAACACG
AGAGTTTGTGCTGTTGCCGGCAGCTTCGGAGTTGGCTCATGTGAAGCAACTAGCCTGTTCTATC
GTGGACCAGAAGTTCCCAGAGTGTGGCTTCTACGGCCTGTACGACAAGATCCTGCTCTTCAAAC
ATGACCCAACATCAGCCAACCTCCTGCAGCTGGTGCGATCAGCTGCAGATATCCAGGAGGGCGA
CTTGGTGGAGGTGGTTCTGTCGGCCTCAGCCACCTTCGAGGATTTCCAGATCCGTCCGCATGCT
CTCACTGTGCACTCGTACCGCGCACCAGCTTTCTGTGACCACTGTGGGGAGATGCTGTTTGGCC
TTGTGCGCCAGGGCCTCAAGTGCGATGGCTGCGGGCTGAATTACCACAAACGCTGCGCCTTCAG
CATCCCGAACAACTGCAGTGGCGCTCGGAAGCGCAGACTGTCATCCACGTCTCTGGCCAGTGGC
CATTCTGTGCGTCTCGGCAGCTCCGAGTCCCTACCCTGCACCGCCGAAGAGCTGAGCCGTAGCA
CCACCGACCTCCTTCCTCGCCGACCACCCTCGTCGTCGTCCTCCTCCTCTTCCTCTTCCTTCTA
CACAGGCCGACCCATTGAGCTGGACAAGATGCTGATGTCCAAGGTCAAGGTGCCACACACCTTC
CTTATACATAGCTACACACGGCCCACCGTTTGCCAGGCTTGCAAGAAACTGCTCAAGGGTCTCT
TCCGCCAGGGCCTGCAGTGCAAAGACTGCAAGTTTAACTGTCACAAACGCTGTGCTACCCGAGT
CCCTAATGACTGCCTGGGGGAGGCGCTCATCAATGGAGATGTGCCCATGGAAGAAGCTGCTGAT
TACAGTGAGGCTGATAAGAGCTCCCTCTCAGATGAGTTGGAGGACTCTGGTGTCATCCCAGGCT
CCCATGCAGAGAATGCTCTCCATGCCAGTGAGGAAGAGGAAGGCGAGGGAGGCAAGGCCCAGAG
CTCGCTGGGCTACATCCCCCTGATGCGTGTGGTACAGTCTGTGCGACACACGACCCGGAAATCC
AGCACCACCCTGCGGGAGGGCTGGGTGGTCCATTACAGCAACAAGGACACACTGAGGAAGCGGC
ACTACTGGCGCCTAGACTGCAAATGCATTACCCTCTTCCAGAACAACACGACCAACAGATACTA
CAAGGAGATCCCGCTGTCTGAAATCCTCGCAGTGGAGCCGGCTCAGAACTTCAGCCTCGTACCT
CCGGGCACCAACCCACACTGCTTTGAGATCATCACCGCCAATGTCACCTACTTTGTGGGCGAGA
CACCTGGCGGGGCCCCGGGAGGGCCGAGCGGGCAGGGAACAGAGGCTGCCCGGGGTTGGGAGAC
AGCCATCCGCCAGGCACTGATGCCTGTTATCCTCCAAGATGCACCCAGTGCCCCAGGCCACACA
CCACACAGACAAGCTTCTCTGAGCATCTCTGTGTCCAACAGTCAGATCCAAGAGAACGTGGACA
TCGCCACTGTCTACCAGATCTTCCCCGATGAGGTGCTGGGCTCTGGACAGTTTGGAGTGGTCTA
TGGAGGAAAACACAGGAAGACTGGCAGAGATGTTGCAGTAAAGGTCATTGACAAACTACGCTTC
CCCACCAAGCAGGAGAGCCAGCTCAGGAATGAAGTGGCCATCCTCCAGAGCCTGCGGCACCCCG
GGATTGTGAACCTCGAGTGCATGTTTGAGACCCCTGAGAAGGTATTCGTGGTGATGGAGAAACT
GCATGGGGACATGTTGGAGATGATCCTCTCCAGTGAGAAGGGCCGGCTTCCTGAGCGCCTCACC
AAGTTCCTTATCACGCAGATTCTGGTGGCACTGAGACACCTACACTTCAAGAACATCGTCCACT
GTGACTTGAAACCAGAGAATGTGTTACTGGCATCAGCCGATCCGTTTCCTCAGGTGAAGCTATG
TGACTTCGGCTTCGCTCGCATCATCGGTGAGAAGTCCTTCCGGCGCTCAGTGGTGGGCACGCCC
GCCTACCTGGCACCTGAGGTACTGCTCAACCAGGGTTACAACCGCTCGCTGGACATGTGGTCCG
TGGGTGTGATCATGTATGTGAGCCTCAGTGGCACGTTTCCCTTCAATGAGGACGAGGACATCAA
TGACCAGATACAGAATGCAGCCTTTATGTACCCGGCCAGCCCCTGGAGCCACATCTCATCTGGA
GCCATCGACCTCATCAACAACCTGTTGCAGGTGAAGATGCGCAAGCGCTACAGCGTGGACAAGT
CTCTCAGCCACCCATGGTTACAGGAGTACCAGACGTGGCTTGACCTCCGAGAGCTAGAGGGAAA
GATGGGCGAGCGATATATCACCCATGAGAGCGACGACGCACGCTGGGATCAGTTTGTATCAGAG
CGCCATGGGACGCCTGCAGAAGGGGACCTGGGTGGCGCCTGTCTGCCACAGGACCATGAGATGC
AGGGGCTGGCTGAGCGGATCAGCATCCTCTGAGGCCAGTGTTCCCCGCTGGGCTGCTTGCTTTC
TTTGGAGTCCTGCACATCATCCTAAAAGTGAACTGTTCTAGAGGAAGCAGCTTTCTGCACAGAC
TGAATGAGGCATTATGCAGGAGGGCCAGGGCTCTCTCTCTTTCCCGTCACTGAAATAGACTGTT
CCCAGGGCAATGATTTTAGTCTCTGATGCCCCAATCTTGGAGTGATAAGGCTGGAGAGTTGGTT
CTGTGGGTAAAGGCGCTTGCCACCAAGCCTAACAAGTTGAGTTTGATTCCTGGGATGAACCTCT
TTGGAGAATTGACTGCCGTTTGCCCCCTGACCACCACATGTGCACACACAAACACAGACAATAA
ATGTATTT

hide sequence

RefSeq Acc Id:

XM_039103912 ⟹ XP_038959840

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,648,521 - 86,670,476 (+)	NCBI
mRatBN7.2	1	77,520,425 - 77,542,386 (+)	NCBI

RefSeq Acc Id:

XM_063283083 ⟹ XP_063139153

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,640,095 - 86,670,476 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013917	(Get FASTA)	NCBI Sequence Viewer
	XP_038959840	(Get FASTA)	NCBI Sequence Viewer
	XP_063139153	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83592	(Get FASTA)	NCBI Sequence Viewer
	EDM08302	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022360
	ENSRNOP00000022360.3
	ENSRNOP00000101544
GenBank Protein	Q5XIS9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013917 ⟸ NM_001013895

- UniProtKB:

Q5XIS9 (UniProtKB/Swiss-Prot), A0A8I6AR64 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAPSHPAGLPCSPGPGSPPPPGGSDLQSLPPLLPQIPAPGSGVSFHIQIGLTREFVLLPAAS
ELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSAS
ATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGAR
KRRLSSTSLASGHSVRLGSSESLPCTAEELSRSTTDLLPRRPPSSSSSSSSSSFYTGRPIELDK
MLMSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEAL
INGDVPMEEAADYSEADKSSLSDELEDSGVIPGSHAENALHASEEEEGEGGKAQSSLGYIPLMR
VVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEIL
AVEPAQNFSLVPPGTNPHCFEIITANVTYFVGETPGGAPGGPSGQGTEAARGWETAIRQALMPV
ILQDAPSAPGHTPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGR
DVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMIL
SSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIG
EKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFM
YPASPWSHISSGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHE
SDDARWDQFVSERHGTPAEGDLGGACLPQDHEMQGLAERISIL

hide sequence

Ensembl Acc Id:

ENSRNOP00000022360 ⟸ ENSRNOT00000022360

RefSeq Acc Id:	XP_038959840 ⟸ XM_039103912
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000096969 ⟸ ENSRNOT00000117563

RefSeq Acc Id:	XP_063139153 ⟸ XM_063283083
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIS9 (UniProtKB/Swiss-Prot), A0A8I6AR64 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000101544 ⟸ ENSRNOT00000136993

Protein Domains

PH Phorbol-ester/DAG-type Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIS9-F1-model_v2	AlphaFold	Q5XIS9	1-875	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689740

Promoter ID:

EPDNEW_R265

Type:

multiple initiation site

Name:

Prkd2_1

Description:

protein kinase D2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	78,767,818 - 78,767,878	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308054	AgrOrtholog
BioCyc Gene	G2FUF-60592	BioCyc
Ensembl Genes	ENSRNOG00000016434	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022360	ENTREZGENE
	ENSRNOT00000022360.6	UniProtKB/Swiss-Prot
	ENSRNOT00000136993	ENTREZGENE
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
	3.30.60.20	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7132731	IMAGE-MGC_LOAD
InterPro	C1-like_sf	UniProtKB/Swiss-Prot
	DAG/PE-bd	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	PE/DAG-bd	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Protein_Kinase_C_mu-related	UniProtKB/Swiss-Prot
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot
KEGG Report	rno:292658	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94325	IMAGE-MGC_LOAD
NCBI Gene	292658	ENTREZGENE
PANTHER	PTHR22968	UniProtKB/Swiss-Prot
	SERINE/THREONINE-PROTEIN KINASE D2	UniProtKB/Swiss-Prot
Pfam	C1_1	UniProtKB/Swiss-Prot
	PF00169	UniProtKB/Swiss-Prot
	Pkinase	UniProtKB/Swiss-Prot
PhenoGen	Prkd2	PhenoGen
PIRSF	PKC_mu_nu_D2	UniProtKB/Swiss-Prot
PRINTS	DAGPEDOMAIN	UniProtKB/Swiss-Prot
PROSITE	PH_DOMAIN	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot
	ZF_DAG_PE_1	UniProtKB/Swiss-Prot
	ZF_DAG_PE_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000016434	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot
	SM00109	UniProtKB/Swiss-Prot
	SM00233	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
	SSF56112	UniProtKB/Swiss-Prot
	SSF57889	UniProtKB/Swiss-Prot
UniProt	A0A8I6AR64	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LI79_RAT	UniProtKB/TrEMBL
	A6J8D2_RAT	UniProtKB/TrEMBL
	KPCD2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Prkd2	protein kinase D2	RGD1308054	similar to protein kinase D2	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1308054	similar to protein kinase D2	RGD1308054_predicted	similar to protein kinase D2 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1308054_predicted	similar to protein kinase D2 (predicted)	LOC292658_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC292658_predicted	similar to protein kinase D2 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD