Sh2d4a (SH2 domain containing 4A) - Rat Genome Database

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Gene: Sh2d4a (SH2 domain containing 4A) Rattus norvegicus
Analyze
Symbol: Sh2d4a
Name: SH2 domain containing 4A
RGD ID: 1307991
Description: Predicted to enable phosphatase binding activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SH2D4A (SH2 domain containing 4A); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC306376; SH2 domain-containing 4A; SH2 domain-containing protein 4A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81626,106,721 - 26,176,069 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1626,106,730 - 26,175,974 (-)EnsemblGRCr8
mRatBN7.21621,339,010 - 21,409,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1624,719,964 - 24,789,247 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01628,151,974 - 28,221,432 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01624,085,301 - 24,154,602 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01623,084,247 - 23,156,825 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)Ensemblrn6Rnor6.0
Rnor_5.01622,972,707 - 23,044,750 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41622,957,569 - 23,027,864 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1621,499,092 - 21,568,252 (-)NCBICelera
RGSC_v3.11622,957,570 - 23,027,862 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benomyl  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
DDE  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
flutamide  (EXP)
gentamycin  (EXP)
indometacin  (ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
N-ethyl-N-nitrosourea  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17251388   PMID:19389623   PMID:31904090  


Genomics

Comparative Map Data
Sh2d4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81626,106,721 - 26,176,069 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1626,106,730 - 26,175,974 (-)EnsemblGRCr8
mRatBN7.21621,339,010 - 21,409,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1624,719,964 - 24,789,247 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01628,151,974 - 28,221,432 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01624,085,301 - 24,154,602 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01623,084,247 - 23,156,825 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)Ensemblrn6Rnor6.0
Rnor_5.01622,972,707 - 23,044,750 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41622,957,569 - 23,027,864 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1621,499,092 - 21,568,252 (-)NCBICelera
RGSC_v3.11622,957,570 - 23,027,862 (-)NCBI
Cytogenetic Map16p14NCBI
SH2D4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38819,313,693 - 19,396,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl819,313,693 - 19,396,695 (+)Ensemblhg38GRCh38
GRCh37819,171,204 - 19,253,729 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36819,215,483 - 19,297,596 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34819,215,486 - 19,297,594NCBI
Celera818,134,620 - 18,217,068 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef817,711,708 - 17,794,051 (+)NCBIHuRef
CHM1_1819,372,569 - 19,455,187 (+)NCBICHM1_1
T2T-CHM13v2.0819,578,579 - 19,661,102 (+)NCBIT2T-CHM13v2.0
Sh2d4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39868,729,180 - 68,800,356 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl868,729,219 - 68,800,351 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38868,276,528 - 68,347,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl868,276,567 - 68,347,699 (+)Ensemblmm10GRCm38
MGSCv37870,800,427 - 70,871,603 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36871,205,517 - 71,277,048 (+)NCBIMGSCv36mm8
Celera870,819,013 - 70,892,695 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.76NCBI
Sh2d4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540343,111,804 - 43,170,397 (+)Ensembl
ChiLan1.0NW_00495540343,111,804 - 43,170,344 (+)NCBIChiLan1.0ChiLan1.0
SH2D4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2737,793,026 - 37,875,297 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1813,518,712 - 13,601,393 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0818,536,774 - 18,619,073 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1815,486,658 - 15,568,497 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl815,486,659 - 15,568,497 (+)EnsemblpanPan2panpan1.1
SH2D4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11622,138,555 - 22,209,326 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1622,143,602 - 22,209,341 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1622,644,579 - 22,715,648 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01623,878,894 - 23,950,089 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1623,879,595 - 23,951,068 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11622,237,393 - 22,308,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01622,822,486 - 22,893,799 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01622,875,425 - 22,946,531 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sh2d4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494314,934,352 - 14,997,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365553,572,694 - 3,636,161 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365553,572,723 - 3,634,484 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100518097
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11712,506,451 - 12,588,526 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21710,284,074 - 10,325,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH2D4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1817,401,254 - 17,484,141 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl817,406,951 - 17,484,839 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605224,765,241 - 24,848,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh2d4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475815,132,839 - 15,191,795 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475815,132,580 - 15,195,063 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sh2d4a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11321,038,619 - 21,100,994 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sh2d4a
613 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:102
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000018543
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat

Markers in Region
D16Rat76  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81626,128,129 - 26,128,267 (+)Marker Load Pipeline
mRatBN7.21621,361,414 - 21,361,552 (+)MAPPERmRatBN7.2
Rnor_6.01623,105,700 - 23,105,837NCBIRnor6.0
Rnor_5.01622,994,160 - 22,994,297UniSTSRnor5.0
RGSC_v3.41622,978,935 - 22,979,073RGDRGSC3.4
RGSC_v3.41622,978,936 - 22,979,073UniSTSRGSC3.4
Celera1621,520,505 - 21,520,642UniSTS
RGSC_v3.11622,978,933 - 22,979,071RGD
RH 3.4 Map16269.8UniSTS
RH 3.4 Map16269.8RGD
RH 2.0 Map16301.8RGD
SHRSP x BN Map169.04RGD
Cytogenetic Map16p14UniSTS
RH129030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21621,360,498 - 21,360,682 (+)MAPPERmRatBN7.2
Rnor_6.01623,104,784 - 23,104,967NCBIRnor6.0
Rnor_5.01622,993,244 - 22,993,427UniSTSRnor5.0
RGSC_v3.41622,978,020 - 22,978,203UniSTSRGSC3.4
Celera1621,519,589 - 21,519,772UniSTS
RH 3.4 Map16262.3UniSTS
Cytogenetic Map16p14UniSTS
AA925855  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21621,340,098 - 21,340,303 (+)MAPPERmRatBN7.2
Rnor_6.01623,084,340 - 23,084,544NCBIRnor6.0
Rnor_5.01622,972,800 - 22,973,004UniSTSRnor5.0
RGSC_v3.41622,957,662 - 22,957,866UniSTSRGSC3.4
Celera1621,499,185 - 21,499,389UniSTS
RH 3.4 Map16256.76UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 148 91 90 59 74 59 6 338 174 11 127 81 92 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000018543   ⟹   ENSRNOP00000018543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1626,106,730 - 26,175,974 (-)Ensembl
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)Ensembl
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112358   ⟹   ENSRNOP00000083552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1626,106,730 - 26,161,341 (-)Ensembl
mRatBN7.2 Ensembl1621,340,015 - 21,394,624 (-)Ensembl
RefSeq Acc Id: NM_001012048   ⟹   NP_001012048
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81626,106,721 - 26,175,974 (-)NCBI
mRatBN7.21621,340,006 - 21,409,260 (-)NCBI
Rnor_6.01623,084,247 - 23,156,825 (-)NCBI
Rnor_5.01622,972,707 - 23,044,750 (-)NCBI
RGSC_v3.41622,957,569 - 23,027,864 (-)RGD
Celera1621,499,092 - 21,568,252 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094496   ⟹   XP_038950424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81626,106,721 - 26,176,069 (-)NCBI
mRatBN7.21621,339,010 - 21,409,360 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012048 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950424 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79100 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018543
  ENSRNOP00000018543.3
GenBank Protein Q6AYC8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012048   ⟸   NM_001012048
- UniProtKB: Q6AYC8 (UniProtKB/Swiss-Prot),   A0A8I5ZXE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018543   ⟸   ENSRNOT00000018543
RefSeq Acc Id: XP_038950424   ⟸   XM_039094496
- Peptide Label: isoform X1
- UniProtKB: Q6AYC8 (UniProtKB/Swiss-Prot),   A0A8I5ZXE8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083552   ⟸   ENSRNOT00000112358
Protein Domains
SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYC8-F1-model_v2 AlphaFold Q6AYC8 1-422 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700060
Promoter ID:EPDNEW_R10583
Type:multiple initiation site
Name:Sh2d4a_1
Description:SH2 domain containing 4A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01623,156,928 - 23,156,988EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307991 AgrOrtholog
BioCyc Gene G2FUF-11687 BioCyc
Ensembl Genes ENSRNOG00000013541 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018543 ENTREZGENE
  ENSRNOT00000018543.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7124466 IMAGE-MGC_LOAD
InterPro SH2 UniProtKB/Swiss-Prot
  SH2_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:306376 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94080 IMAGE-MGC_LOAD
NCBI Gene 306376 ENTREZGENE
PANTHER SH2 DOMAIN-CONTAINING PROTEIN 4A UniProtKB/Swiss-Prot
  T CELL-SPECIFIC ADAPTER PROTEIN TSAD UniProtKB/Swiss-Prot
Pfam SH2 UniProtKB/Swiss-Prot
PhenoGen Sh2d4a PhenoGen
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot
PROSITE SH2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013541 RatGTEx
SMART SH2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF55550 UniProtKB/Swiss-Prot
UniProt A0A8I5ZXE8 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYC8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Sh2d4a  SH2 domain containing 4A  Sh2d4a_predicted  SH2 domain containing 4A (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sh2d4a_predicted  SH2 domain containing 4A (predicted)      Symbol and Name status set to approved 70820 APPROVED