Gene: Supt20h (SPT20 homolog, SAGA complex component) Rattus norvegicus
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Symbol:
Supt20h
Name:
SPT20 homolog, SAGA complex component
RGD ID:
1307812
Description:
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Predicted to be part of SAGA complex. Orthologous to human SUPT20H (SPT20 homolog, SAGA complex component); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Fam48a; family with sequence similarity 48, member A; LOC361946; RGD1307812; similar to transcription factor (p38 interacting protein); suppressor of Ty 20; Supt20; transcription factor (p38 interacting protein); transcription factor SPT20 homolog
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SUPT20H (SPT20 homolog, SAGA complex component)
HGNC
Ensembl, NCBI, Panther
Mus musculus (house mouse):
Supt20 (SPT20 SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Supt20h (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SUPT20H (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SUPT20H (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Supt20h (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SUPT20H (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
SUPT20H (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Supt20h (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Supt20h (SPT20 homolog, SAGA complex component)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
SUPT20HL1 (SUPT20H like 1)
HGNC
Panther
Homo sapiens (human):
SUPT20HL2 (SUPT20H like 2)
HGNC
Panther
Alliance orthologs 3
Mus musculus (house mouse):
Supt20 (SPT20 SAGA complex component)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Supt20 (SPT20 SAGA complex component)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Homo sapiens (human):
SUPT20H (SPT20 homolog, SAGA complex component)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|SonicParanoid)
Homo sapiens (human):
SUPT20H (SPT20 homolog, SAGA complex component)
Alliance
DIOPT (HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
supt20 (SPT20 homolog, SAGA complex component)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Spt20
Alliance
DIOPT (Ensembl Compara|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Spt20
Alliance
DIOPT (Ensembl Compara|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
supt20h
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
supt20h
Alliance
DIOPT (OrthoFinder|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 141,047,479 - 141,080,656 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 141,047,477 - 141,081,361 (+) Ensembl GRCr8 mRatBN7.2 2 138,897,316 - 138,930,493 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 138,897,416 - 138,930,495 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 145,471,532 - 145,504,744 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 143,583,554 - 143,616,770 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 138,215,391 - 138,248,605 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 143,892,609 - 143,925,733 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 143,892,567 - 143,925,633 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 160,337,768 - 160,370,787 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 143,921,831 - 143,955,032 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 133,382,206 - 133,415,296 (+) NCBI Celera RGSC_v3.1 2 143,871,793 - 143,904,995 (+) NCBI Cytogenetic Map 2 q26 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Supt20h Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Supt20 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Supt20h Rat 1,2-dimethylhydrazine increases expression ISO Supt20 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of SUPT20 mRNA CTD PMID:22206623 Supt20h Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Supt20 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Supt20h Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Supt20 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Supt20h Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Supt20 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Supt20h Rat 2-methylcholine affects expression ISO SUPT20H (Homo sapiens) 6480464 beta-methylcholine affects the expression of SUPT20H mRNA CTD PMID:21179406 Supt20h Rat 3,4-methylenedioxymethamphetamine increases expression ISO Supt20 (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SUPT20 mRNA CTD PMID:20188158|PMID:26251327 Supt20h Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Supt20h Rat acrolein multiple interactions ISO SUPT20H (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268 Supt20h Rat alpha-pinene multiple interactions ISO SUPT20H (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268 Supt20h Rat antirheumatic drug increases expression ISO SUPT20H (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of SUPT20H mRNA CTD PMID:24449571 Supt20h Rat benzo[a]pyrene increases methylation ISO SUPT20H (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of SUPT20H promoter CTD PMID:27901495 Supt20h Rat benzo[a]pyrene diol epoxide I decreases expression ISO SUPT20H (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SUPT20H mRNA CTD PMID:19150397 Supt20h Rat beta-lapachone decreases expression ISO SUPT20H (Homo sapiens) 6480464 beta-lapachone results in decreased expression of SUPT20H mRNA CTD PMID:38218311 Supt20h Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SUPT20H mRNA CTD PMID:30816183 Supt20h Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Supt20h Rat bisphenol A decreases expression ISO Supt20 (Mus musculus) 6480464 bisphenol A results in decreased expression of SUPT20 mRNA CTD PMID:32156529 Supt20h Rat bisphenol A decreases methylation ISO SUPT20H (Homo sapiens) 6480464 bisphenol A results in decreased methylation of SUPT20H gene CTD PMID:31601247 Supt20h Rat bisphenol F decreases expression ISO Supt20 (Mus musculus) 6480464 bisphenol F results in decreased expression of SUPT20 mRNA CTD PMID:38685157 Supt20h Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Supt20h Rat cadmium atom multiple interactions ISO SUPT20H (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SUPT20H more ... CTD PMID:35301059 Supt20h Rat cadmium dichloride multiple interactions ISO SUPT20H (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SUPT20H more ... CTD PMID:35301059 Supt20h Rat caffeine decreases phosphorylation ISO SUPT20H (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of SUPT20H protein CTD PMID:35688186 Supt20h Rat copper atom increases expression EXP 6480464 Copper results in increased expression of SUPT20 mRNA CTD PMID:30556269 Supt20h Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of SUPT20 mRNA CTD PMID:30556269 Supt20h Rat crocidolite asbestos decreases expression ISO Supt20 (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of SUPT20 mRNA CTD PMID:29279043 Supt20h Rat dibutyl phthalate decreases expression ISO Supt20 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of SUPT20 mRNA CTD PMID:21266533 Supt20h Rat dioxygen multiple interactions ISO Supt20 (Mus musculus) 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of SUPT20 mRNA CTD PMID:30529165 Supt20h Rat doxorubicin decreases expression ISO SUPT20H (Homo sapiens) 6480464 Doxorubicin results in decreased expression of SUPT20H mRNA CTD PMID:29803840 Supt20h Rat emodin increases expression ISO SUPT20H (Homo sapiens) 6480464 Emodin results in increased expression of SUPT20H mRNA CTD PMID:16045814 Supt20h Rat folic acid decreases expression ISO Supt20 (Mus musculus) 6480464 Folic Acid results in decreased expression of SUPT20 mRNA CTD PMID:25629700 Supt20h Rat FR900359 decreases phosphorylation ISO SUPT20H (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of SUPT20H protein CTD PMID:37730182 Supt20h Rat methylmercury chloride decreases expression ISO SUPT20H (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of SUPT20H mRNA CTD PMID:28001369 Supt20h Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of SUPT20 mRNA CTD PMID:24136188 Supt20h Rat ozone multiple interactions ISO SUPT20H (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268 Supt20h Rat PCB138 multiple interactions ISO Supt20 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Supt20h Rat phenobarbital affects expression ISO Supt20 (Mus musculus) 6480464 Phenobarbital affects the expression of SUPT20 mRNA CTD PMID:23091169 Supt20h Rat silicon dioxide decreases expression ISO Supt20 (Mus musculus) 6480464 Silicon Dioxide results in decreased expression of SUPT20 mRNA CTD PMID:19073995 Supt20h Rat sodium arsenite increases expression ISO Supt20 (Mus musculus) 6480464 sodium arsenite results in increased expression of SUPT20 mRNA CTD PMID:36209798 Supt20h Rat sulforaphane multiple interactions ISO Supt20 (Mus musculus) 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of SUPT20 mRNA CTD PMID:30529165 Supt20h Rat sunitinib decreases expression ISO SUPT20H (Homo sapiens) 6480464 Sunitinib results in decreased expression of SUPT20H mRNA CTD PMID:31533062 Supt20h Rat titanium dioxide decreases methylation ISO Supt20 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of SUPT20 promoter CTD PMID:35295148 Supt20h Rat trichostatin A increases expression ISO SUPT20H (Homo sapiens) 6480464 trichostatin A results in increased expression of SUPT20H mRNA CTD PMID:24935251 Supt20h Rat triptonide increases expression ISO Supt20 (Mus musculus) 6480464 triptonide results in increased expression of SUPT20 mRNA CTD PMID:33045310 Supt20h Rat troglitazone decreases expression ISO Supt20 (Mus musculus) 6480464 troglitazone results in decreased expression of SUPT20 mRNA CTD PMID:28973697 Supt20h Rat valproic acid decreases expression ISO Supt20 (Mus musculus) 6480464 Valproic Acid results in decreased expression of SUPT20 mRNA CTD PMID:21427059 Supt20h Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of SUPT20 mRNA CTD PMID:23034163 Supt20h Rat vincristine increases expression ISO SUPT20H (Homo sapiens) 6480464 Vincristine results in increased expression of SUPT20H mRNA CTD PMID:23649840