Tmem14a (transmembrane protein 14A)

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Gene: Tmem14a (transmembrane protein 14A) Rattus norvegicus

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Symbol:

Tmem14a

Name:

transmembrane protein 14A

RGD ID:

1307710

Description:

Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and regulation of heme biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in mitochondrial membrane. Orthologous to human TMEM14A (transmembrane protein 14A); INTERACTS WITH 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC103693210; LOC363206

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM14A (transmembrane protein 14A)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Tmem14a (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem14a (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM14A (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM14A (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem14a (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM14A (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM14A (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem14a (transmembrane protein 14A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TMEM14A (transmembrane protein 14A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem14a (transmembrane protein 14A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:163080	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG5532	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tmem14a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	31,137,011 - 31,148,794 (+)	NCBI		GRCr8
mRatBN7.2	9	23,640,594 - 23,652,379 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	23,640,594 - 23,652,379 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	9	23,733,039 - 23,734,463 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	32,131,886 - 32,145,560 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	37,252,577 - 37,266,255 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	35,567,818 - 35,581,496 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	27,333,956 - 27,345,612 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,333,956 - 27,351,295 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,343,853 - 27,345,070 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	26,187,241 - 26,198,598 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	19,986,826 - 19,999,299 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	19,984,156 - 19,996,628 (+)	NCBI
Celera	9	21,214,591 - 21,228,190 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (EXP)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

Didecyldimethylammonium (ISO)

dioxygen (ISO)

diquat (ISO)

doxorubicin (ISO)

folic acid (ISO)

furan (EXP)

hydrogen peroxide (ISO)

lead(0) (ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of apoptotic process (ISO)

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (ISO)

regulation of heme biosynthetic process (IBA)

Cellular Component

endoplasmic reticulum membrane (ISO)

mitochondrial membrane (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21723035	PMID:38054547

Genomics

Comparative Map Data

Tmem14a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	31,137,011 - 31,148,794 (+)	NCBI		GRCr8
mRatBN7.2	9	23,640,594 - 23,652,379 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	23,640,594 - 23,652,379 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	9	23,733,039 - 23,734,463 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	32,131,886 - 32,145,560 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	37,252,577 - 37,266,255 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	35,567,818 - 35,581,496 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	27,333,956 - 27,345,612 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,333,956 - 27,351,295 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,343,853 - 27,345,070 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	26,187,241 - 26,198,598 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	19,986,826 - 19,999,299 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	19,984,156 - 19,996,628 (+)	NCBI
Celera	9	21,214,591 - 21,228,190 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

TMEM14A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	52,671,113 - 52,686,588 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	52,671,113 - 52,686,588 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	52,535,911 - 52,551,386 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	52,643,843 - 52,659,345 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	52,643,863 - 52,659,342	NCBI
Celera	6	54,196,977 - 54,212,463 (+)	NCBI		Celera
Cytogenetic Map	6	p12.2	NCBI
HuRef	6	52,367,119 - 52,382,535 (+)	NCBI		HuRef
CHM1_1	6	52,538,093 - 52,553,590 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	52,509,853 - 52,525,372 (+)	NCBI		T2T-CHM13v2.0

Tmem14a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	21,236,609 - 21,300,391 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	21,288,799 - 21,300,391 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	21,166,436 - 21,230,167 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	21,218,575 - 21,230,167 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	21,208,712 - 21,220,248 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	21,203,813 - 21,215,315 (+)	NCBI		MGSCv36	mm8
Celera	1	21,087,828 - 21,099,400 (+)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.5	NCBI

Tmem14a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	5,373,251 - 5,379,767 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	5,372,713 - 5,380,033 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM14A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	67,135,737 - 67,157,973 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	63,018,973 - 63,034,401 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	52,226,416 - 52,241,846 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	53,492,943 - 53,508,340 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	53,492,943 - 53,508,340 (+)	Ensembl	panpan1.1		panPan2

TMEM14A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	20,303,724 - 20,318,336 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	20,198,868 - 20,213,473 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	20,801,318 - 20,815,838 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	12	20,307,098 - 20,321,683 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	20,410,701 - 20,425,306 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	20,549,342 - 20,563,953 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem14a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	55,761,976 - 55,780,517 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	8,180,141 - 8,185,884 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	8,179,949 - 8,198,204 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM14A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	46,509,777 - 46,517,732 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	46,509,724 - 46,517,735 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	134,211,575 - 134,218,991 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM14A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	19,819,918 - 19,835,919 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	19,820,458 - 19,829,781 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	52,574,544 - 52,590,827 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem14a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	3,388,847 - 3,394,990 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	3,388,292 - 3,411,943 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem14a
165 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	486
Count of miRNA genes:	253
Interacting mature miRNAs:	309
Transcripts:	ENSRNOT00000037489, ENSRNOT00000072794
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
724543	Cm20	Cardiac mass QTL 20	3.9		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	16961398	40594091	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	13533770	42791750	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	22133322	49968732	Rat

Markers in Region

RH137565

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	23,652,090 - 23,652,242 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	27,351,007 - 27,351,158	NCBI	Rnor6.0
Rnor_6.0	9	27,345,317 - 27,345,468	NCBI	Rnor6.0
Rnor_5.0	9	26,203,830 - 26,203,981	UniSTS	Rnor5.0
Rnor_5.0	9	26,198,310 - 26,198,461	UniSTS	Rnor5.0
RGSC_v3.4	9	19,999,011 - 19,999,162	UniSTS	RGSC3.4
Celera	9	21,227,902 - 21,228,053	UniSTS
RH 3.4 Map	9	229.6	UniSTS
Cytogenetic Map	9	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
15	11	55	139	119	114	71	31	71	12	269	121	107	54	78	43

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000037489 ⟹ ENSRNOP00000032359

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	23,640,594 - 23,652,379 (+)	Ensembl
Rnor_6.0 Ensembl	9	27,333,956 - 27,351,295 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000072794 ⟹ ENSRNOP00000066651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	23,733,039 - 23,734,463 (-)	Ensembl
Rnor_6.0 Ensembl	9	27,343,853 - 27,345,070 (+)	Ensembl

RefSeq Acc Id:

NM_001108790 ⟹ NP_001102260

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	31,137,011 - 31,148,794 (+)	NCBI
mRatBN7.2	9	23,640,594 - 23,652,379 (+)	NCBI
Rnor_6.0	9	27,333,956 - 27,345,605 (+)	NCBI
Rnor_5.0	9	26,187,241 - 26,198,598 (+)	NCBI
RGSC_v3.4	9	19,986,826 - 19,999,299 (+)	RGD
Celera	9	21,214,591 - 21,228,190 (+)	RGD

Sequence:

show sequence

TGCTGGCCCAGACCTGCACCTCCCTCCCAGGCTGTGAACGGCAGAAGGGTATGGGATCGAGGAC
TCCACCCCTCCCGAACCAGCTCCAGAAAGCACTTAGCTTTGTGTAGTTCGTTCGGGTCGCAGCT
AGGGAGTGCGCCTGCGCTGCACTGCTTCCGGATTGAGGGACTGCCCTTGCGCATCACCGCTTTT
TCCGCCTTCTCCAGCTGCTGCAAGGGCTCAAGGGTGCAGACTTGCGTCCTTATCAATGGACTTG
ATTGGTTTTGGTTATGCAGCCCTTGTGACAATTGGAAGTGTTTTGGGATATAAGCGAAGAGGTG
GAGTTCCATCTCTGATTGCTGGGCTCTCTGTAGGCCTTTTGGCTGGCTATGGAGCCTACCGTGT
CTCCAATGACAAACGGGATGTCAAAGTGTCACTGTTTACAGCTTTCTTCCTGGCCACCATAATG
GGTGTGAGATTTAAGAGGTCCAAGAAAGTAATGCCTGCTGGTCTAGTCGCAGGCTTAAGCCTCA
TGATGATCCTGAGACTTGTCCTGCTGCTGCTGTAGCATCCAGAGAAGCGGAGAGCCAAACTCCC
ACCATGCTGCTGGGCCTGGCAGAGCAGGCTCTTGCTTTAGAGTGATCAATTTAAATACATGGGA
AATGTCTTACATCGAAATGAAAATAATGTTGTCACCCTAATATTTAAGAATAATTGGCAATGTT
TATTCGTTCCCCCTGCAACGCCTTTTTATTTAATTTGATTTTAGATGTTTCCATTTGTAAATCC
CAGTCTTTCGTGAATTATGACATGCTTGTTTGCTTTGACTCACTTTGTATCTGGAAATTGGGGG
CTGGATATTTTCTGCCTTTGACAATCCCAGACACTTAGGACTAAAATAAGTTAACTGCAACCTG
TCAGAAGATGGGACTGCTGGAGGGGACCACAGGGAGTGTGAATGAGCTGTGTGTGACTTTGTCC
ATTAGGGGTTCTGTTTGCATTGTTGGGGGTGGAGTAAGTTTGCACTGAAGGGATTCTGTTCTCA
GTACATCAAATCCTGACCAAATGTAATCAGTGTTTAAATAAAATGCATCGTATTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102260	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM18638	(Get FASTA)	NCBI Sequence Viewer
	EDM18639	(Get FASTA)	NCBI Sequence Viewer
	EDM18640	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032359.4
	ENSRNOP00000066651.2

RefSeq Acc Id:	NP_001102260 ⟸ NM_001108790
- UniProtKB:	D3ZUB4 (UniProtKB/TrEMBL), A6JJ92 (UniProtKB/TrEMBL), A6JJ93 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLIGFGYAALVTIGSVLGYKRRGGVPSLIAGLSVGLLAGYGAYRVSNDKRDVKVSLFTAFFLA TIMGVRFKRSKKVMPAGLVAGLSLMMILRLVLLLL hide sequence

Ensembl Acc Id:

ENSRNOP00000066651 ⟸ ENSRNOT00000072794

Ensembl Acc Id:

ENSRNOP00000032359 ⟸ ENSRNOT00000037489

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZUB4-F1-model_v2	AlphaFold	D3ZUB4	1-99	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307710	AgrOrtholog
BioCyc Gene	G2FUF-28009	BioCyc
Ensembl Genes	ENSRNOG00000013238	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000046593	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000037489.5	UniProtKB/TrEMBL
	ENSRNOT00000072794.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.1740	UniProtKB/TrEMBL
	6.10.250.1330	UniProtKB/TrEMBL
InterPro	TMEM14_sf	UniProtKB/TrEMBL
	UPF0136_TM	UniProtKB/TrEMBL
KEGG Report	rno:363206	UniProtKB/TrEMBL
NCBI Gene	363206	ENTREZGENE
PANTHER	TRANSMEMBRANE PROTEIN 14A	UniProtKB/TrEMBL
	UPF0136_TM	UniProtKB/TrEMBL
Pfam	Tmemb_14	UniProtKB/TrEMBL
PhenoGen	Tmem14a	PhenoGen
RatGTEx	ENSRNOG00000013238	RatGTEx
	ENSRNOG00000046593	RatGTEx
UniProt	A6JJ92	ENTREZGENE, UniProtKB/TrEMBL
	A6JJ93	ENTREZGENE, UniProtKB/TrEMBL
	D3ZUB4	ENTREZGENE, UniProtKB/TrEMBL
	M0RAU2_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-06-07	Tmem14a	transmembrane protein 14A	LOC103693210	transmembrane protein 14A	Data merged from RGD:9417885	737654	PROVISIONAL
2014-08-25	LOC103693210	transmembrane protein 14A			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Tmem14a	transmembrane protein 14A	Tmem14a_predicted	transmembrane protein 14A (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tmem14a_predicted	transmembrane protein 14A (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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